Title of Invention | FLUOROALKYLOXYCOMBRETASTATIN DERIVATIVES, METHODS FOR PRODUCING SAME |
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Abstract | Combretastatin derivatives of formula (I) , preparation and use thereof are disclosed, wherein: R,is alkyl with 1-8 carbon atoms and 1-17 fluorine atoms , R is amino, substituted amino, hydroxyl, nitro, halo, alkyloxy, phosphate or amino acid side chain. Said derivatives have a capability to inhibit the polymerization of microtubules and are useful in treatment against tumor and neovascularization. |
Full Text | PLEASE SEE THE SPECIFICATION ATTACHED. |
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2792-MUMNP-2008-ABSTRACT(12-9-2012).pdf
2792-MUMNP-2008-ABSTRACT(30-12-2008).pdf
2792-MUMNP-2008-CLAIMS(30-12-2008).pdf
2792-MUMNP-2008-CLAIMS(AMENDED)-(12-9-2012).pdf
2792-MUMNP-2008-CLAIMS(MARKED COPY)- (12-9-2012).pdf
2792-MUMNP-2008-CLAIMS(MARKED COPY)-(12-9-2012).pdf
2792-MUMNP-2008-CORRESONDENCE(8-9-2009).pdf
2792-MUMNP-2008-CORRESPONDENCE(10-8-2009).pdf
2792-MUMNP-2008-CORRESPONDENCE(5-3-2010).pdf
2792-MUMNP-2008-CORRESPONDENCE(7-8-2009).pdf
2792-MUMNP-2008-DESCRIPTION(COMPLETE)-(30-12-2008).pdf
2792-MUMNP-2008-DRAWING(12-9-2012).pdf
2792-MUMNP-2008-DRAWING(30-12-2008).pdf
2792-MUMNP-2008-EP DOCUMENT(12-9-2012).pdf
2792-MUMNP-2008-FORM 1(10-8-2009).pdf
2792-MUMNP-2008-FORM 1(30-12-2008).pdf
2792-MUMNP-2008-FORM 18(5-3-2010).pdf
2792-MUMNP-2008-FORM 2(COMPLETE)-(30-12-2008).pdf
2792-MUMNP-2008-FORM 2(TITLE PAGE)-(30-12-2008).pdf
2792-MUMNP-2008-FORM 26(10-8-2009).pdf
2792-MUMNP-2008-FORM 3(12-9-2012).pdf
2792-MUMNP-2008-FORM 3(30-12-2008).pdf
2792-MUMNP-2008-FORM 3(9-9-2009).pdf
2792-MUMNP-2008-FORM 5(30-12-2008).pdf
2792-MUMNP-2008-MARKED COPY(12-9-2012).pdf
2792-MUMNP-2008-OTHER DOCUMENT(12-9-2012).pdf
2792-MUMNP-2008-PETITION UNDER RULE 137(9-9-2009).pdf
2792-MUMNP-2008-REPLY TO EXAMINATION REPORT(12-9-2012).pdf
2792-MUMNP-2008-US DOCUMENT(12-9-2012).pdf
Patent Number | 255273 | |||||||||||||||||||||
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Indian Patent Application Number | 2792/MUMNP/2008 | |||||||||||||||||||||
PG Journal Number | 06/2013 | |||||||||||||||||||||
Publication Date | 08-Feb-2013 | |||||||||||||||||||||
Grant Date | 08-Feb-2013 | |||||||||||||||||||||
Date of Filing | 30-Dec-2008 | |||||||||||||||||||||
Name of Patentee | ZHEJIANG DADE PHARMACEUTICAL GROUP CO. LTD. | |||||||||||||||||||||
Applicant Address | 289 West Jiangbin Road Yiwu Zhejiang 322000, | |||||||||||||||||||||
Inventors:
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PCT International Classification Number | C07C43/23 | |||||||||||||||||||||
PCT International Application Number | PCT/CN2006/003149 | |||||||||||||||||||||
PCT International Filing date | 2006-11-22 | |||||||||||||||||||||
PCT Conventions:
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