Title of Invention

FLUOROALKYLOXYCOMBRETASTATIN DERIVATIVES, METHODS FOR PRODUCING SAME

Abstract Combretastatin derivatives of formula (I) , preparation and use thereof are disclosed, wherein: R,is alkyl with 1-8 carbon atoms and 1-17 fluorine atoms , R is amino, substituted amino, hydroxyl, nitro, halo, alkyloxy, phosphate or amino acid side chain. Said derivatives have a capability to inhibit the polymerization of microtubules and are useful in treatment against tumor and neovascularization.
Full Text PLEASE SEE THE SPECIFICATION ATTACHED.

Documents:

2792-MUMNP-2008-ABSTRACT(12-9-2012).pdf

2792-MUMNP-2008-ABSTRACT(30-12-2008).pdf

2792-MUMNP-2008-CLAIMS(30-12-2008).pdf

2792-MUMNP-2008-CLAIMS(AMENDED)-(12-9-2012).pdf

2792-MUMNP-2008-CLAIMS(MARKED COPY)- (12-9-2012).pdf

2792-MUMNP-2008-CLAIMS(MARKED COPY)-(12-9-2012).pdf

2792-MUMNP-2008-CORRESONDENCE(8-9-2009).pdf

2792-MUMNP-2008-CORRESPONDENCE(10-8-2009).pdf

2792-MUMNP-2008-CORRESPONDENCE(5-3-2010).pdf

2792-MUMNP-2008-CORRESPONDENCE(7-8-2009).pdf

2792-MUMNP-2008-DESCRIPTION(COMPLETE)-(30-12-2008).pdf

2792-MUMNP-2008-DRAWING(12-9-2012).pdf

2792-MUMNP-2008-DRAWING(30-12-2008).pdf

2792-MUMNP-2008-EP DOCUMENT(12-9-2012).pdf

2792-MUMNP-2008-FORM 1(10-8-2009).pdf

2792-MUMNP-2008-FORM 1(30-12-2008).pdf

2792-MUMNP-2008-FORM 18(5-3-2010).pdf

2792-MUMNP-2008-FORM 2(COMPLETE)-(30-12-2008).pdf

2792-MUMNP-2008-FORM 2(TITLE PAGE)-(30-12-2008).pdf

2792-MUMNP-2008-FORM 26(10-8-2009).pdf

2792-MUMNP-2008-FORM 3(12-9-2012).pdf

2792-MUMNP-2008-FORM 3(30-12-2008).pdf

2792-MUMNP-2008-FORM 3(9-9-2009).pdf

2792-MUMNP-2008-FORM 5(30-12-2008).pdf

2792-MUMNP-2008-MARKED COPY(12-9-2012).pdf

2792-MUMNP-2008-OTHER DOCUMENT(12-9-2012).pdf

2792-MUMNP-2008-PETITION UNDER RULE 137(9-9-2009).pdf

2792-MUMNP-2008-REPLY TO EXAMINATION REPORT(12-9-2012).pdf

2792-MUMNP-2008-US DOCUMENT(12-9-2012).pdf

abstract1.jpg

Drawings.PDF

Form-1.pdf

Form-3.pdf

Form-5.pdf


Patent Number 255273
Indian Patent Application Number 2792/MUMNP/2008
PG Journal Number 06/2013
Publication Date 08-Feb-2013
Grant Date 08-Feb-2013
Date of Filing 30-Dec-2008
Name of Patentee ZHEJIANG DADE PHARMACEUTICAL GROUP CO. LTD.
Applicant Address 289 West Jiangbin Road Yiwu Zhejiang 322000,
Inventors:
# Inventor's Name Inventor's Address
1 SHEN Weiping Room 101 No. 28 Lane 699 North Huangzhen Road Shanghai 200436 China
2 WANG Jianping 289 West Jiangbin Road Yiwu Zhejiang 322000 China
3 WANG Jianguo 289 West Jiangbin Road Yiwu Zhejiang 322000 China
4 JIN Hongmei 99 Shangda Road SHANGHAI 200444 China
5 QIAN Feng 99 Shangda Road SHANGHAI 200444 China
6 WANG Fei 99 Shangda Road SHANGHAI 200444 China
PCT International Classification Number C07C43/23
PCT International Application Number PCT/CN2006/003149
PCT International Filing date 2006-11-22
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 200610027307.6 2006-06-06 China