| Title of Invention | A METHOD OF TESTING THE ABILITY OF A TEST COMPOUND TO MODULATE THE ACTIVITY OF A POLYPEPTIDE OF THE JMJD2 SUBFAMILY OF JUMONJI PROTEINS |
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| Abstract | The present invention provides a method of testing the ability of a test compound to bind to and optionally modulate the activity of a protein of the JMJD2 subfamily of Jumonji proteins. The method comprises incubating a test compound with a protein of the JMJD2 subfamily of Jumonji proteins, a co-factor of said protein and, optionally, a substrate for demethylation. The method of the invention can be used for screening large numbers of compounds to identify a group of compounds that are candidate compounds for clinical use for treatment of certain cancers especially prostate cancers. Other compounds that do not have activity in the screening assays can be eliminated from further consideration as candidate compounds. The method of the invention therefore has utility in the pharmaceutical industry. |
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1919-mumnp-2008-amended claims.pdf
1919-mumnp-2008-assignment(24-11-2008).pdf
1919-MUMNP-2008-CLAIMS(AMENDED)-(2-7-2012).pdf
1919-MUMNP-2008-CLAIMS(AMENDED)-(3-4-2012).pdf
1919-MUMNP-2008-CLAIMS(MARKED COPY)-(2-7-2012).pdf
1919-MUMNP-2008-CLAIMS(MARKED COPY)-(3-4-2012).pdf
1919-MUMNP-2008-CORRESPONDENC(25-02-2009).pdf
1919-MUMNP-2008-CORRESPONDENCE(19-1-2012).pdf
1919-MUMNP-2008-CORRESPONDENCE(19-7-2012).pdf
1919-mumnp-2008-correspondence(21-11-2008).pdf
1919-MUMNP-2008-CORRESPONDENCE(24-11-2008).pdf
1919-MUMNP-2008-CORRESPONDENCE(3-3-2010).pdf
1919-MUMNP-2008-CORRESPONDENCE(6-1-2011).pdf
1919-MUMNP-2008-CORRESPONDENCE(7-1-2011).pdf
1919-mumnp-2008-correspondence.pdf
1919-MUMNP-2008-DECLARATION(24-11-2008).pdf
1919-mumnp-2008-description(complete).doc
1919-mumnp-2008-description(complete).pdf
1919-MUMNP-2008-DRAWING(3-4-2012).pdf
1919-MUMNP-2008-EP DOCUMENT(19-7-2012).pdf
1919-MUMNP-2008-FORM 1(2-7-2012).pdf
1919-MUMNP-2008-FORM 1(24-11-2008).pdf
1919-mumnp-2008-form 1(8-9-2008).pdf
1919-mumnp-2008-form 18(3-3-2010).pdf
1919-MUMNP-2008-FORM 2(TITLE PAGE)-(2-7-2012).pdf
1919-mumnp-2008-form 2(title page).pdf
1919-MUMNP-2008-FORM 26(24-11-2008).pdf
1919-MUMNP-2008-FORM 3(19-1-2012).pdf
1919-MUMNP-2008-FORM 3(19-7-2012).pdf
1919-MUMNP-2008-FORM 3(24-11-2008).pdf
1919-MUMNP-2008-FORM 3(25-02-2009).pdf
1919-mumnp-2008-form 3(25-2-2009).pdf
1919-MUMNP-2008-FORM 3(6-1-2011).pdf
1919-mumnp-2008-form 3(8-9-2008).pdf
1919-MUMNP-2008-FORM 5(24-11-2008).pdf
1919-mumnp-2008-form 5(8-9-2008).pdf
1919-mumnp-2008-form 6(24-11-2008).pdf
1919-MUMNP-2008-OTHER DOCUMENT(7-1-2011).pdf
1919-mumnp-2008-pct-ib-304.pdf
1919-MUMNP-2008-PCT-IB-306(24-11-2008).pdf
1919-mumnp-2008-pct-ib-306.pdf
1919-mumnp-2008-pct-ipea-409.pdf
1919-mumnp-2008-pct-ipea-416.pdf
1919-MUMNP-2008-PETITION UNDER RULE 137(2-7-2012).pdf
1919-MUMNP-2008-REPLY TO EXAMINATION REPORT(2-7-2012).pdf
1919-MUMNP-2008-REPLY TO EXAMINATION REPORT(3-4-2012).pdf
1919-mumnp-2008-sequence listing.pdf
1919-mumnp-2008-wo international publication report a2.pdf
| Patent Number | 253672 | ||||||||||||||||||
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| Indian Patent Application Number | 1919/MUMNP/2008 | ||||||||||||||||||
| PG Journal Number | 33/2012 | ||||||||||||||||||
| Publication Date | 17-Aug-2012 | ||||||||||||||||||
| Grant Date | 10-Aug-2012 | ||||||||||||||||||
| Date of Filing | 08-Sep-2008 | ||||||||||||||||||
| Name of Patentee | Københavns Universitet | ||||||||||||||||||
| Applicant Address | Norregade 10 DK-1165 Knbenhavn K Denmark | ||||||||||||||||||
Inventors:
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| PCT International Classification Number | G01N33/68 | ||||||||||||||||||
| PCT International Application Number | PCT/DK2007/000128 | ||||||||||||||||||
| PCT International Filing date | 2007-03-14 | ||||||||||||||||||
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