Title of Invention | FUNGICIDAL MIXTURES |
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Abstract | Fungicidal mixtures, comprising as active components 1) carbamate oxime ethers of the formula I, in which X is N or CH, and 2) at least one active compound II selected from the group of the azoles, stro- bilurins, carboxamides, heterocyclic compounds, carbamates, guanidines, antibiotics, nitrophenyl derivatives, sulfur-containing heterocyclyl com- pounds, organometallic compounds, organophosphorus compounds, or- ganochlorine compounds, inorganic active compounds, cyflufenamid, cy- moxanil, dimethirimol, ethirimol, furalaxyl, metrafenone and spiroxamine, in a synergistically effective amount, methods for controlling harmful fungi using mix- tures of the compound I with active compounds II, the use of the compound I with ac- tive compounds II for preparing such mixtures and compositions comprising these mix- tures. |
Full Text | PF 56210 1 Fungicidal mixtures Description The present invention relates to fungicidal mixtures comprising, as active components, 1) carbamate oxime ethers of the formula I, in which X is N or CH, and 2) at least one active compound II selected from the following groups: A) azoles, such as bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, enilconazole, epoxiconazole, fluquinconazole, fenbuconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simeconazole, triadimefon, triadimenol, tebuconazole, tetraconazole, triticonazole, prochloraz, pefurazoate, imazalil, triflumizole, cyazofamid, benomyl, carbendazim, thiabendazole, fuberidazole, ethaboxam, etridiazole, hymexazole, B) strobilurins, such as azoxystrobin, dimoxystrobin, enestroburin, fluoxa- strobin, kresoxim-methyl, metominostrobin, orysastrobin, picoxystrobin, pyraclostrobin, trifloxystrobin; C) carboxamides, such as carboxin, benalaxyl, boscalid, fenhexamid, flutolanil, furametpyr, mepronil, metalaxyl, mefenoxam, ofurace, oxadixyl, oxycarboxin, penthiopyrad, thifluzamide, tiadinil, 3,4-dichloro-N-(2-cyanophenyl)isothiazole-5-carboxamide, dimethomorph, flumorph, flumetover, fluopicolide (picobenzamid), zoxamide, carpropamid, diclocymet, mandipropamid, N-(2-{4-[3-(4-chlorophenyl)prop-2-ynyloxy]-3-methoxyphenyl}ethyl)-2- methanesulfonylamino-3-methylbutyramide, N-(2-{4-[3-(4-chlorophenyl)prop-2-ynyloxy]-3-methoxyphenyl}ethyl)-2- ethanesulfonylamino-3-methylbutyramide, amides of the formula III, PF 56210 2 in which the variables and the index are as defined below: R1 and R2 independently of one another are hydrogen, halogen, C1-C6-alkyl or C1-C6 haloalkyl, cyano, nitro, methoxy or trifluoromethoxy, with the proviso that R1 and R2 are not simultaneously hydrogen, and R3 is CF3 or CHF2; D) heterocyclic compounds, such as fluazinam, pyrifenox, bupirimate, cyprodinil, fenarimol, ferimzone, mepanipyrim, nuarimol, pyrimethanil, triforine, fenpiclonil, fludioxonil, aldimorph, dodemorph, fenpropimorph, tridemorph, fenpropidin, iprodione, procymidone, vinclozolin, famoxadone, fenamidone, octhilinone, probenazole, 5-chloro-7-(4-methylpiperidin-1-yl)-6-(2,4,6-trifluorophenyl)-[1,2,4]tri- azolo[1,5-a]pyrimidine, anilazine, diclomezine, pyroquilon, proquinazid, tricyclazole, 2-butoxy-6-iodo-3-propylchromen-4-one acibenzolar-S-methyl, captafol, captan, dazomet, folpet, fenoxanil, quin- oxyfen, or N,N-dimethyl-3-(3-bromo-6-fluoro-2-methylindole-1-sulfonyl)-[1,2,4]triazole- 1-sulfonamide; E) carbamates, such as mancozeb, maneb, metam, metiram, ferbam, propineb, thiram, zineb, ziram, diethofencarb, iprovalicarb, flubenthiavalicarb, propamocarb, methyl 3-(4-chlorophenyl)-3-(2-isopropoxycarbonylamino-3-methyl-butyryl- amino)propanoate, PF 56210 3 and F) other fungicides, selected from the group consisting of guanidines: dodine, iminoctadine, guazatine, antibiotics: kasugamycin, streptomycin, polyoxine, validamycin A, nitrophenyl derivatives: binapacryl, dinocap, dinobuton, sulfur-containing heterocyclyl compounds: dithianon, isoprothiolane, organometallic compounds: fentin salts, such as fentin acetate, organophosphorus compounds: edifenphos, iprobenfos, fosetyl, fosetyl aluminum, phosphorous acid and its salts, pyrazophos, tolclofos-methyl, organochlorine compounds: chlorothalonil, dichlofluanid, flusulfamide, hexachlorobenzene, phthalide, pencycuron, quintozene, thiophanate- methyl, tolylfluanid, inorganic active compounds: Bordeaux mixture, copper acetate, copper hydroxide, copper oxychloride, basic copper sulfate, sulfur, others: cyflufenamid, cymoxanil, dimethirimol, ethirimol, furalaxyl, metrafenone and spiroxamine, in a synergistically effective amount. In addition, the invention relates to a method for controlling harmful fungi using mixtures of the compound I with active compounds II, to the use of the compound I with active compounds II for preparing such mixtures and to compositions comprising these mixtures. The oxime ethers, referred to above as component 1, of the formula I, their preparation and their action against harmful fungi are known from the literature (EP-A 12 01 648). The active compounds II, mentioned above as component 2, their preparation and their action against harmful fungi are generally known (cf.: http://www.hclrss.demon.co.uk/index.html); they are commercially available. Bitertanol, P-([1,1 '-biphenyl]-4-yloxy)-a-(1,1 -dimethylethy!)-1 H-1,2,4-triazole-1 -ethanol (DE 23 24 020), bromuconazole, 1-[[4-bromo-2-(2,4-dichlorophenyl)tetrahydro-2-furanyl]methyl]-1H- 1,2,4-triazole (Proc. 1990 Br. Crop. Prot. Conf. -Pests Dis. Vol. 1, p. 459), cyproconazole, 2-(4-chlorophenyl)-3-cyclopropyl-1 -[1,2,4]triazol-1 -ylbutan-2-ol (US 4 664 696); difenoconazole, 1-{2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-[1,3]dioxolan-2- ylmethyl}-1H-[1,2,4]triazole (GB-A 2 098 607); diniconazole, (bE)-p-[(2,4-dichlorophenyl)methylene]-a-(1,1-dimethylethyl)-1H-1,2,4- triazole-1 -ethanol (Noyaku Kagaku, 1983, Vol. 8, p. 575), PF 56210 4 enilconazole (imazalil), 1 -[2-(2,4-dichlorophenyl)-2-(2-propenyloxy)ethyl]-1 H-imidazole (Fruits, 1973, Vol. 28, p. 545), epoxiconazole, (2RS,3SR)-1-[3-(2-chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]- 1H-1,2,4-triazole (EP-A 196 038); fluquiconazole, 3-(2,4-dichlorophenyl)-6-fluoro-2-[1,2,4]-triazol-1-yl-3H-quinazolin-4- one (Proc. Br. Crop Prot. Conf.-Pests Dis., 5-3, 411 (1992)); fenbuconazole, a-[2-(4-chlorophenyl)ethyl]-a-phenyl-1H-1,2,4-triazole-1-propannitrile (Proc. 1988 Br. Crop Prot. Conf. - Pests Dis. Vol. 1, p. 33), flusilazole, 1-{[bis-(4-fluorophenyl)methylsilanyl]methyl}-1H-[1,2,4]triazole (Proc. Br. Crop Prot. Conf.-Pests Dis., 1, 413 (1984)); flutriafol, a-(2-fluorophenyl)-a-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol (EP 15 756), hexaconazole, 2-(2,4-dichlorophenyl)-1-[1,2,4]triazo!-1-ylhexan-2-ol (CAS RN [79983-71-4]); imibenconazole, (4-chlorophenyl)methyl N-(2,4-dichlorophenyl)-1 H-1,2,4-triazole-1 - ethaneimidothioate ((Proc. 1988 Br. Crop Prot. Conf. - Pests Dis. Vol. 2, p. 519), ipconazole, 2-[(4-chlorophenyl)methyl]-5-(1-methylethyl)-1-(1H-1,2,4-triazol-1-yl- methyl)cydopentanol (EP 267 778), metconazole, 5-(4-chlorobenzyl)-2,2-dimethyl-1 -[1,2,4]triazol-1 -ylmethylcyclopentanol (GB 857 383); myclobutanil, 2-(4-chlorophenyl)-2-[1,2,4]triazol-1-ylmethylpentanenitrile (CAS RN [88671-89-0]); penconazole, 1-[2-(2,4-dichlorophenyl)pentyl]-1H-[1,2,4]triazole (Pesticide Manual, 12th Ed. (2000), page 712); propiconazole, 1 -[[2-(2,4-dichlorphenyl)-4-propyl-1,3-dioxolan-2-yl]methyl]-1 H-1,2,4- triazole (BE 835 579), prothioconazole, 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4- dihydro[1,2,4]triazol-3-thione (WO 96/16048); simeconazole, a-(4-fluorophenyl)-a-[(trimethylsilyl)methyl]-1 H-1,2,4-triazole-1 -ethanol [CAS RN 149508-90-7], triadimefon, 1 -(4-chlorophenoxy)-3,3-dimethyl-1 -(1 H-1,2,4-triazol-1 -yl)-2-butanone; triadimenol, b-(4-chlorophenoxy)-a-(1,1-dimethylethyl)-1 H-1,2,4-triazole-1-ethanol; tebuconazole, 1 -(4-chlorophenyl)-4,4-dimethyl-3-[1,2,4]triazol-1 -ylmethylpentan-3-o! (EP-A 40 345); tetraconazole, 1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1H-1,2,4- triazole (EP 234 242), triticonazole, (5E)-5-[(4-chlorophenyl)methylene]-2,2-dimethyl-1 -(1 H-1,2,4-triazol-1 - ylmethyl)cyclopentanol (FR 26 41 277), prochloraz, N-{propyl-[2-(2,4,6-trichlorophenoxy)ethyl]}imidazole-1-carboxamide (US 3 991 071); PF 56210 5 pefurazoate,4-pentenyl2-[(2-furanylmethyl)(1H-imidazol-1-ylcarbonyl)amino]butanoate [CAS RN 101903-30-4], triflumizole, (4-chloro-2-trifluoromethylphenyl)-(2-propoxy-1-[1,2,4]triazol-1-ylethyli- dene)amine (JP-A 79/119 462) cyazofamid, 4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1 H-imidazole-1 -sulfon- amide (CAS RN 120116-88-3], benomyl, N-butyl-2-acetylaminobenzoimidazole-1-carboxamide (US 3 631 176); carbendazim, methyl (1H-benzoimidazol-2-yl)-carbamate (US 3 657 443); thiabendazole, 2-(1,3-thiazol-4-yl)benzimidazole (US 3 017 415), fuberidazole, 2-(2-furanyl)-1H-benzimidazole (DE 12 09 799), ethaboxam, N-(cyano-2-thienylmethyl)-4-ethyl-2-(ethylamino)-5-thiazolecarboxamide (EP-A 639 574), etridiazole, hymexazole, 5-methyl-1,2-oxazol-3-ol (JP 518249, JP 532202), azoxystrobin, methyl 2-{2-[6-(2-cyano-1-vinylpenta-1,3-dienyloxy)pyrimidin-4- yloxy]phenyl}-3-methoxyacrylate (EP-A 382 375), dimoxystrobin, (E)-2-(methoxyimino)-N-methyl-2-[a-(2,5-xylyloxy)-o-tolyl]acetamide (EP-A 477 631); fluoxastrobin, (E)-{2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yloxy]phenyl}(5,6- dihydro-1,4,2-dioxazin-3-yl)methanone O-methyloxime (WO 97/27189); kresoxim-methyl, methyl (E)-methoxyimino[a-(o-tolyloxy)-o-tolyl]acetate (EP-A 253 213); metominostrobin, (E)-2-(methoxyimino)-N-methyl-2-(2-phenoxyphenyl)acetamide (EP- A 398 692); orysastrobin, (2E)-2-(methoxyimino)-2-{2-[(3E,5E,6E)-5-(methoxyimino)-4,6-dimethyl- 2,8-dioxa-3,7-diazanona-3,6-dien-1 -yl]phenyl}-N-methylacetamide (WO 97/15552); picoxystrobin, methyl 3-methoxy-2-[2-(6-trifluoromethylpyridin-2-yloxymethyl)phenyl]- acrylate (EP-A 278 595); pyraclostrobin, methyl N-{2-[1-(4-chlorophenyl)-1H-pyrazol-3-yloxymethyl]phenyl}(N- methoxy)carbamate (WO-A 96/01256); trifloxystrobin, methyl (E)-methoxyimino-{(E)-a-[1-(a,a,a-trifluoro-m-tolyl)ethylidene- aminooxy]-o-tolyl}acetate (EP-A 460 575); carboxin, 5,6-dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide (US 3 249 499), benalaxyl, methyl N-(phenylacetyl)-N-(2,6-xylyl)-DL-alaninate (DE 29 03 612), boscalid, 2-chloro-N-(4'-chlorbiphenyl-2-yl)nicotinamide (EP-A 545 099); fenhexamid, N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide (Proc. Br. Crop Prot. Conf. - Pests Dis., 1998, Vol. 2, p. 327); flutolanil, a,a,a-trifluoro-3'-isopropoxy-o-toluanilide (JP 1104514), furametpyr, 5-chloro-N-(1,3-dihydro-1,1,3-trimethyl-4-isobenzofuranyl)-1,3-dimethyl-1 H- pyrazole-4-carboxamide [CAS RN 123572-88-3], PF 56210 6 mepronil, 3'-isopropoxy-o-toluanilide (US 3 937 840), metalaxyl, methyl N-(methoxyacetyl)-N-(2,6-xylyl)-DL-alaninate (GB 15 00 581); mefenoxam, methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)-D-alaninate; ofurace, (RS)-a-(2-chloro-N-2,6-xylylacetamido)-Y-butyrolactone [CAS RN 58810-48-3]; oxadixyl; N-(2,6-dimethylphenyl)-2-methoxy-N-(2-oxo-3-oxazolidinyl)acetamide (GB 20 58 059), oxycarboxin, 5,6-dihydro-2-methyl-1,4-oxathiin-3-carboxanilide 4,4-dioxide (US 3 399 214), penthiopyrad, N-[2-(1,3-dimethylbutyl)-3-thienyl]-1-methyl-3-(trifluoromethyl)-1H- pyrazole-4-carboxamide (JP 10130268), thifluzamide, tiadinil, 3'-chloro-4,4'-dimethyl-1,2,3-thiadiazole-5-carboxanilide [CAS RN 223580-51- 6], dimethomorph, 3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylpropenone (EP-A120 321); flumorph, 3-(4-fluorophenyl)-3-(3,4-dimethoxyphenyl)-1 -morpholin-4-ylpropenone (EP- A 860 438); flumetover, 2-(3,4-dimethoxyphenyl)-N-ethyl-a,a,a-trifluoro-N-methyl-p-toluamide [AGROW No. 243, 22 (1995)], fluopicolide (picobenzamid), 2,6-dichloro-N-(3-chloro-5-trifluoromethylpyridin-2- ylmethyl)benzamide (WO 99/42447); zoxamide, (RS)-3,5-dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-p-toluamide [CAS RN 156052-68-5]; carpropamid, 2,2-dichloro-N-[1-(4-chlorophenyl)ethyl]-1-ethyl-3-methylcyclopropane- carboxamide [CAS RN 104030-54-8], diclocymet, 2-cyano-N-[(1R)-1-(2,4-dichlorophenyl)ethyl]-3,3-dimethylbutanamide; mandipropamid, (RS)-2-(4-chlorophenyl)-N-[3-methoxy-4-(prop-2-ynyloxy)phenethyl]-2- (prop-2-ynyloxy)acetamide [CAS RN 374726-62-2]; fluazinam, 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)- 2-pyridinamine (The Pesticide Manual, publ. The British Crop Protection Council, 10th ed. (1995), p. 474); pyrifenox, 1-(2,4-dichlorophenyl)-2-(3-pyridinyl)ethanone O-methyloxime (EP-A 49 854); bupirimate, cyprodinil, (4-cyclopropyl-6-methylpyrimidin-2-yl)phenylamine (EP-A 310 550); fenarimol, (4-chlorophenyl)-(2-chlorophenyl)pyrimidin-5-ylmethanol (GB 12 18 623); ferimzone, (Z)-2'-methylacetophenone 4,6-dimethylpyrimidin-2-ylhydrazone; mepanipyrim, (4-methyl-6-prop-1-ynylpyrimidin-2-yl)phenylamine (EP-A224 339); nuarimol, a-(2-chlorophenyl)-a-(4-fluorophenyl)-5-pyrimidinemethanol (GB 12 18 623); pyrimethanil, 4,6-dimethylpyrimidin-2-ylphenylamine (DD-A 151 404); PF 56210 7 triforine, N,N'-{piperazine-1,4-diylbis[(trichloromethyl)methylene]}diformamide (DE 19 01 421); fenpiclonil, 4-(2,3-dichlorophenyl)-1H-pyrrole-3-carbonitrile (Proc. 1988 Br. Crop Prot. Conf. - Pests Dis., Vol. 1, p. 65); fludioxonil, 4-(2,2-difIuorobenzo[1,3]dioxol-4-yl)-1H-pyrrole-3-carbonitrile (The Pesticide Manual, publ. The British Crop Protection Council, 10th ed. (1995), p. 482); aldimorph, 4-alkyl-2,5(or 2,6)-dimethylmorpholine, comprising 65-75% of 2,6-dimethyl- morpholine and 25-35% of 2,5-dimethylmorpholine, comprising more than 85% of 4- dodecyl-2,5(or 2,6)-dimethylmorpholine, where "alkyl" may also include octyl, decyl, tetradecyl and hexadecyl and where the cis/trans ratio is 1:1; dodemorph, 4-cyclododecyl-2,6-dimethylmorpholine (DE 1198125); fenpropimorph, (RS)-cis-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethyl- morpholine (DE 27 52 096); tridemorph, 2,6-dimethyl-4-tridecylmorpholine (DE 11 64 152); fenpropidin, (RS)-1-[3-(4-ferf-butylphenyl)-2-methylpropyl]piperidine (DE 27 52 096); iprodione, N-isopropyl-3-(3,5-dichlorophenyl)-2,4-dioxoimidazoNdine-1-carboxamide (GB 13 12 536); procymidone, A/-(3,5-dichlorophenyl)-1,2-dimethylcyclopropane-1,2-dicarboximide (US 3 903 090); vinclozolin, 3-(3,5-dichlorophenyl)-5-methyl-5-vinyloxazolidine-2,4-dione (DE-OS 22 07 576); famoxadone, (RS)-3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione; fenamidone, (S)-1-anilino-4-methyl-2-methylthio-4-phenylimidazolin-5-one; octhilinone, probenazole, 3-allyloxy-1,2-benzothiazole 1,1-dioxide [CAS RN 27605-76-1]; anilazine, 4,6-dichloro-A/-(2-chlorophenyl)-1,3,5-triazine-2-amine (US 2 720 480); diclomezine, 6-(3,5-dichlorophenyl-p-tolyl)pyridazin-3(2H)-one; pyroquilone, 1,2,5,6-tetrahydropyrrolo[3,2,1-ij]quinolin-4-one (GB 13 94 373); proquinazid, 6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one (WO 97/48684); tricyclazole, 5-methyl-1,2,4-triazolo[3,4-jb]benzothiazole (GB 14 19 121); acibenzolar-S-methyl, methyl benzo[1,2,3]thiadiazole-7-carbothionate; captafol, N-(1,1,2,2-tetrachloroethylthio)cyclohex-4-ene-1,2-dicarboximide; captan, 2-trichloromethylsulfanyl-3a,4,7,7a-tetrahydroisoindole-1,3-dione (US 2 553 770); dazomet, 3,5-dimethyl-1,3,5-thiadiazinane-2-thione; folpet, 2-trichloromethylsulfanylisoindole-1,3-dione (US 2 553 770); fenoxanil, N-(1-cyano-1,2-dimethylpropyl)-2-(2,4-dichlorophenoxy)propanamide (EP-A 262 393); quinoxyfen, 5,7-dichloro-4-(4-fluorophenoxy)quinoline (US 5 240 940); PF 56210 8 mancozeb, manganese-ethylenebis(dithiocarbamate) zinc complex (US 3 379 610); maneb, manganese ethylenebis(dithiocarbamate) (US 2 504 404); metam, methyldithiocarbaminic acid (US 2 791 605); metiram, zinc ammoniate ethylenebis(dithiocarbamate) (US 3 248 400); propineb, zinc propylenebis(dithiocarbamate) polymer (BE 611 960); ferbam, iron(3+) dimethyldithiocarbamate (US 1 972 961); thiram, bis(dimethylthiocarbamoyl) disulfide (DE 642 532); ziram, dimethyldithiocarbamate [CAS RN 137-30-4]; zineb, zinc ethylenebis(dithiocarbamate) (US 2 457 674); diethofencarb, isopropyl 3,4-diethoxycarbanilate; iprovalicarb, isopropyl [(1S)-2-methyl-1-(1-p-tolylethylcarbamoyl)propyl]carbamate (EP-A 472 996); flubenthiavalicarb (benthiavalicarb), isopropyl {(S)-1 -[(1 R)-1 -(6-fluorobenzothiazol-2-yl)- ethylcarbamoyl]-2-methylpropyl}carbamate (JP-A 09/323 984); propamocarb, propyl 3-(dimethylamino)propylcarbamate (DE 16 43 040); dodine, (2,4-dichlorophenoxy)acetic acid (US 2 867 562); guazatine, mixture comprising iminoctadine, bis(8-guanidinooctyl)amine (GB 11 14 155); kasugamycin, 1L-1,3,4/2,5,6-1 -deoxy-2,3,4,5,6-pentahydroxycyclohexyl-2-amino- 2,3,4,6-tetradeoxy-4-(a-iminoglycino)-a-D-arabino-hexopyranoside; streptomycin, 0-2-deoxy-2-methylamino-a-L-glucopyranosyl-(1→2)-0-5-deoxy-3-C- formyl-a-L-lyxofuranosyl-(1 →4)-N1,N3-diamidino-D-streptamine; polyoxins, 5-(2-amino-5-O-carbamoyl-2-deoxy-L-xylonamido)-1 -(5-carboxy-1,2,3,4- tetrahydro-2,4-dioxopyrimidin-1-yl)-1,5-dideoxy-b-D-allofuranuronicacid and the salts thereof; validamycin A, binapacryl, (RS)-2-sec-butyl-4,6-dinitrophenyl 3-methylcrotonate; dinocap, the mixture of 2,6-dinitro-4-octy!phenyl crotonate and 2,4-dinitro-6-octylphenyl crotonate, wherein "octyl" is a mixture of 1-methylheptyl, 1-ethylhexyl and 1- propylpentyl (US 2 526 660); dinobuton, (RS)-2-sec-butyl-4,6-dinitrophenyl isopropyl carbonate; dithianon, 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiin-2,3-dicarbonitrile (GB 857 383); isoprothiolane, indol-3-ylacetic acid [CAS RN 50512-35-1]; fentin acetate, triphenyl tin acetate; edifenphos, O-ethyl S,S-diphenylphosphorodithioate; iprobenfos, fosetyl, fosetyl aluminum, ethylphosphonate, aluminum salt (FR 22 54 276); pyrazophos, PF 56210 9 tolclofos-methyl, 0-2,6-dichloro-p-tolyl O,O-dimethyl phosphorothioate (GB 14 67 561); chlorothalonil, 2,4,5,6-tetrachloroisophthalonitrile (US 3 290 353); dichlofluanid, N-dichlorofluoromethylthio-N',N'-dimethyl-N-phenylsulfamide (DE 11 93 498); flusulfamide, hexachlorobenzene, phthalide, pencycuron, 1-(4-chloroben2yl)-1-cyclopentyl-3-phenylurea (DE 27 32 257); quintozene, pentachloronitrobenzene (DE 682 048); thiophanate-methyl, 1,2-phenylenebis(iminocarbonothioyl)bis(dimethylcarbamate) (DE- OS 19 30 540); tolylfluanid, N-dichlorofluoromethylthio-N,N'-dimethyl-N-p-tolylsulfamide (DE 11 93 498); cyflufenamid, (Z)-N-[a-(cyclopropylmethoxyimino)-2,3-difluoro-6-(trifluoromethyl)ben- zyl]-2-phenylacetamide (WO 96/19442); cymoxanil, 1-(2-cyano-2-methoxyiminoacetyl)-3-ethylurea (US 3 957 847); dimethirimol, ethirimol, furalaxyl, metrafenone, 3'-bromo-2,3,4,6'-tetramethoxy-2',6-dimethylbenzophenone (US 5 945 567); spiroxamine, (8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)diethylamine (EP-A281 842). The compounds named according to IUPAC, their preparation and their fungicidal action are likewise known: 5-chloro-7-(4-methylpiperidin-1 -yl)-6-(2,4,6-trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyri- midine (WO 98/46608), R methyl (Il-A) or ethyl (Il-B); amides of the formula III (WO 03/066609), 2-butoxy-6-iodo-3-propylchromen-4-one of the formula IV (WO 03/14103), 3,4-dichloro-N-(2-cyanophenyl)isothiazole-5-carboxamide (WO 99/24413), N-(2-{4-[3-(4-chlorophenyl)prop-2-ynyloxy]-3-methoxyphenyl}ethyl)-2-methanesulfonyl- amino-3-methylbutyramide, N-(2-{4-[3-(4-chlorophenyl)prop-2-ynyloxy]-3- methoxyphenyl}ethyl)-2-ethanesuifonylamino-3-methylbutyramide (WO 04/049804), PF 56210 10 N,N-dimethyl-3-(3-bromo-6-fluoro-2-methylindole-1-sulfonyl)-[1,2,4]tria2ole-1- sulfonamide of the formula V (WO 03/053145), methyl 3-(4-chlorophenyl)-3-(2-isopropoxycarbonylamino-3-methylbutyrylamino)- propanoate of the formula VI (EP-A 1028125). It is an object of the present invention, with a view to reducing the application rates and broadening the activity spectrum of the known compounds, to provide mixtures which, at a reduced total amount of active compounds applied, have improved activity against harmful fungi, in particular for certain indications. We have found that this object is achieved by the mixtures defined at the outset. In addition, we have found that simultaneous, that is joint or separate, application of the compound I and an active compound II or successive application of the compound I and an active compound II allows better control of harmful fungi than is possible with the individual compounds (synergistic mixtures). The compound I can be used as a synergist for a large number of different active compounds. The simultaneous, that is joint or separate, application of the compound I with an active compound II increases the fungicidal activity in a superadditive manner. The mixtures of the compound I and an active compound II or the simultaneous, that is joint or separate, use of the compound I and an active compound II are distinguished by being highly active against a wide range of phytopathogenic fungi, in particular from the classes of the Ascomycetes, Deuteromycetes, Oomycetes and Basidiomycetes. Some of them act systemically and can be used in crop protection as foliar- and soil- acting fungicides. PF 56210 11 They are particularly important for controlling a multitude of fungi on various crop plants, such as bananas, cotton, vegetable species (for example cucumbers, beans and cucurbits), barley, grass, oats, coffee, potatoes, corn, fruit species, rice, rye, soybeans, tomatoes, grapevines, wheat, ornamental plants, sugar cane and on a large number of seeds. They are advantageously suitable for the control of the following phytopathogenic fungi: Blumeria graminis (powdery mildew) on cereals, Erysiphe cichoracearum and Sphaerotheca fuliginea on cucurbits, Podosphaera leucotricha on apples, Uncinula necatoron grapevines, Puccinia species on cereals, Rhizoctonia species on cotton, rice and lawns, Ustilago species on cereals and sugar cane, Venturia inaequalis on apples, Bipolaris and Drechslera species on cereals, rice and lawns, Septoria species on wheat, Botrytis cinerea on strawberries, vegetables, ornamental plants and grapevines, Mycosphaerella species on bananas, peanuts and cereals, Pseudocercosporella herpotrichoides on wheat and barley, Pyricularia oryzae on rice, Phytophthora infestans on potatoes and tomatoes, Pseudoperonospora species on cucurbits and hops, Plasmopara viticola on grapevines, Alternaria species on fruit and vegetables and also Fusarium and Verticillium species. The mixtures of the compound I and an active compound II are especially suitable for controlling Botrytis species. The compound I and active compounds II can be applied simultaneously, that is jointly or separately, or in succession, the sequence, in the case of separate application, generally not having any effect on the result of the control measures. In the definitions of the symbols given for formula III, collective terms were used which denote the following substituents: halogen: fluorine, chlorine, bromine and iodine; alkyl: saturated straight-chain or branched hydrocarbon radicals having 1 to 6 carbon atoms, for example C1-C4alkyl, such as methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1,1-dimethylethyl; haloalkyl: straight-chain or branched alkyl groups having 1 to 6 carbon atoms, where some or all of the hydrogen atoms in these groups may be replaced by halogen atoms as mentioned above: in particular C1-C2-haloalkyl, such as chloromethyl, bromomethyl, dichloromethyl, trichloromethyl, fluoromethyl, difluoromethyl, trifluoromethyl, chlorofluoromethyl, dichlorofluoromethyl, chlorodifluoromethyl, 1-chloroethyl, 1- PF 56210 12 bromoethyl, 1-fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, 2-chloro- 2-fluoroethyl, 2-chloro-2,2-difluoroethyl, 2,2-dichloro-2-fluoroethyl, 2,2,2-trichloroethyl or pentafluoroethyl. The formula I denotes compounds in which X is N (I-A) or CH (I-B). One embodiment of the invention relates to mixtures of the compound I-A with an active compound II. Another embodiment of the invention relates to mixtures of the compound I-B with an active compound II. With a view to the use of the amides of the formula III in the mixtures according to the invention, the following compounds of the formulae IlIa to Illf are particularly suitable: PF 56210 13 Among these, particular preference is given to the compounds of the formula IIId. Especially preferred are the compounds compiled in the tables below: Table 1 Compound 1.1-1.22: compounds of the formula IlIa in which R1 is fluorine and the combination of R2 and R3 is in each case one row of table A Table 2 Compound 2.1 - 2.22: compounds of the formula IlIa in which R1 is chlorine and the combination of R2 and R3 is in each case one row of table A Table 3 Compound 3.1 - 3.22: compounds of the formula IlIa in which R1 is bromine and the combination of R2 and R3 is in each case one row of table A Table 4 Compound 4.1 - 4.22: compounds of the formula IlIa in which R1 is iodine and the combination of R2 and R3 is in each case one row of table A Table 5 Compound 5.1 -5.22: compounds of the formula IlIa in which R1 is methyl and the combination of R2 and R3 is in each case one row of table A Table 6 Compound 6.1 - 6.22: compounds of the formula Ilia in which R1 is methoxy and the combination of R2 and R3 is in each case one row of table A PF 56210 14 Table 7 Compound 7.1 - 7.22: compounds of the formula IlIa in which R1 is trifluoromethyl and the combination of R2 and R3 is in each case one row of table A Table 8 Compound 8.1 - 8.22: compounds of the formula IlIa in which R1 is trifluoromethoxy and the combination of R2 and R3 is in each case one row of table A Table 9 Compound 9.1 - 9.22: compounds of the formula IlIa in which R1 is cyano and the combination of R2 and R3 is in each case one row of table A Table 10 Compound 10.1 - 10.22: compounds of the formula IlIa in which R1 is nitro and R2 is in each case one row of table A Table 11 Compound 11.1 - 11.20: compounds of the formula IlIa in which R1 is hydrogen and the combination of R2 and R3 is in each case one of rows 2 to 21 of table A Table 12 Compound 12.1 - 12.22: compounds of the formula Illb in which R1 is fluorine and the combination of R2 and R3 is in each case one row of table A Table 13 Compound 13.1 - 13.22: compounds of the formula Illb in which R1 is chlorine and the combination of R2 and R3 is in each case one row of table A Table 14 Compound 14.1 - 14.22: compounds of the formula Illb in which R1 is bromine and the combination of R2 and R3 is in each case one row of table A Table 15 Compound 15.1 - 15.22: compounds of the formula Illb in which R1 is iodine and the combination of R2 and R3 is in each case one row of table A Table 16 Compound 16.1 - 16.22: compounds of the formula Illb in which R1 is methyl and the combination of R2 and R3 is in each case one row of table A PF 56210 15 Table 17 Compound 17.1 - 17.22: compounds of the formula Illb in which R1 is methoxy and the combination of R2 and R3 is in each case one row of table A Table 18 Compound 18.1 - 18.22: compounds of the formula Illb in which R1 is trifluoromethyl and the combination of R2 and R3 is in each case one row of table A Table 19 Compound 19.1 - 19.22: compounds of the formula Illb in which R1 is trifluoromethoxy and the combination of R2 and R3 is in each case one row of table A Table 20 Compound 20.1 -20.22: compounds of the formula Illb in which R1 is cyano and the combination of R2 and R3 is in each case one row of table A Table 21 Compound 21.1 -21.22: compounds of the formula Illb in which R1 is nitro and the combination of R2 and R3 is in each case one row of table A Table 22 Compound 22.1 - 22.20: compounds of the formula Illb in which R1 is hydrogen and the combination of R2 and R3 is in each case one of rows 2 to 21 of table A Table 23 Compound 23.1 - 23.22: compounds of the formula Illc in which R1 is fluorine and the combination of R2 and R3 is in each case one row of table A Table 24 Compound 24.1 - 24.22: compounds of the formula Illc in which R1 is chlorine and the combination of R2 and R3 is in each case one row of table A Table 25 Compound 25.1 - 25.22: compounds of the formula Illc in which R1 is bromine and the combination of R2 and R3 is in each case one row of table A Table 26 Compound 26.1 -26.22: compounds of the formula Illc in which R1 is iodine and the combination of R2 and R3 is in each case one row of table A PF 56210 16 Table 27 Compound 25.1 - 25.22: compounds of the formula Illc in which R1 is methyl and the combination of R2 and R3 is in each case one row of table A Table 28 Compound 28.1 -28.22: compounds of the formula Illc in which R1 is methoxy and the combination of R2 and R3 is in each case one row of table A Table 29 Compound 29.1 - 29.22: compounds of the formula Illc in which R1 is trifluoromethyl and the combination of R2 and R3 is in each case one row of table A Table 30 Compound 30.1 - 30.22: compounds of the formula Illc in which R1 is trifluoromethoxy and the combination of R2 and R3 is in each case one row of table A Table 31 Compound 31.1 -31.22: compounds of the formula Illc in which R1 is cyano and the combination of R2 and R3 is in each case one row of table A Table 32 Compound 32.1 - 32.22: compounds of the formula Illc in which R1 is nitro and the combination of R2 and R3 is in each case one row of table A Table 34 Compound 34.1 - 34.22: compounds of the formula IIId in which R1 is fluorine and the combination of R2 and R3 is in each case one row of table A Table 35 Compound 35.1 -35.22: compounds of the formula IIId in which R1 is chlorine and the combination of R2 and R3 is in each case one row of table A Table 36 Compound 36.1 - 36.22: compounds of the formula IIId in which R1 is bromine and the combination of R2 and R3 is in each case one row of table A Table 37 Compound 37.1 -37.22: compounds of the formula IIId in which R1 is iodine and the combination of R2 and R3 is in each case one row of table A PF 56210 17 Table 38 Compound 38.1 -38.22: compounds of the formula IIId in which R1 is methyl and the combination of R2 and R3 is in each case one row of table A Table 39 Compound 39.1 - 39.22: compounds of the formula IIId in which R1 is methoxy and the combination of R2 and R3 is in each case one row of table A Table 40 Compound 40.1 -40.22: compounds of the formula IIId in which R1 is trifluoromethyl and the combination of R2 and R3 is in each case one row of table A Table 41 Compound 41.1 -41.22: compounds of the formula IIId in which R1 is trifluoromethoxy and the combination of R2 and R3 is in each case one row of table A Table 42 Compound 42.1 -42.22: compounds of the formula IIId in which R1 is cyano and the combination of R2 and R3 is in each case one row of table A Table 43 Compound 43.1 -43.22: compounds of the formula IIId in which R1 is nitro and the combination of R2 and R3 is in each case one row of table A Table 44 Compound 44.1 -44.20: compounds of the formula IIId in which R1 is hydrogen and the combination of R2 and R3 is in each case one of rows 2 to 21 of table A Table 45 Compound 45.1 -45.22: compounds of the formula Ille in which R1 is fluorine and the combination of R2 and R3 is in each case one row of table A Table 46 Compound 46.1 -46.22: compounds of the formula Ille in which R1 is chlorine and the combination of R2 and R3 is in each case one row of table A Table 47 Compound 47.1 -47.22: compounds of the formula Ille in which R1 is bromine and the combination of R2 and R3 is in each case one row of table A PF 56210 18 Table 48 Compound 48.1 -48.22: compounds of the formula Ille in which R1 is iodine and the combination of R2 and R3 is in each case one row of table A Table 49 Compound 49.1 -49.22: compounds of the formula Ille in which R1 is methyl and the combination of R2 and R3 is in each case one row of table A Table 50 Compound 50.1 - 50.22: compounds of the formula Ille in which R1 is methoxy and the combination of R2 and R3 is in each case one row of table A Table 51 Compound 51.1 - 51.22: compounds of the formula Ille in which R1 is trifluoromethyl and the combination of R2 and R3 is in each case one row of table A Table 52 Compound 52.1 - 52.22: compounds of the formula Ille in which R1 is trifluoromethoxy and the combination of R2 and R3 is in each case one row of table A Table 53 Compound 53.1 - 53.22: compounds of the formula Ille in which R1 is cyano and the combination of R2 and R3 is in each case one row of table A Table 54 Compound 54.1 - 54.22: compounds of the formula Ille in which R1 is nitro and the combination of R2 and R3 is in each case one row of table A Table 56 Compound 56.1 -56.22: compounds of the formula Illf in which R1 is fluorine and the combination of R2 and R3 is in each case one row of table A Table 57 Compound 57.1 -57.22: compounds of the formula Illf in which R1 is chlorine and the combination of R2 and R3 is in each case one row of table A Table 58 Compound 58.1 - 58.22: compounds of the formula Illf in which R1 is bromine and the combination of R2 and R3 is in each case one row of table A PF 56210 19 Table 59 Compound 59.1 -59.22: compounds of the formula Illf in which R1 is iodine and the combination of R2 and R3 is in each case one row of table A Table 60 Compound 60.1 - 60.22: compounds of the formula Illf in which R1 is methyl and the combination of R2 and R3 is in each case one row of table A Table 61 Compound 61.1 -61.22: compounds of the formula Illf in which R1 is methoxy and the combination of R2 and R3 is in each case one row of table A Table 62 Compound 62.1 - 62.22: compounds of the formula Illf in which R1 is trifluoromethyl and the combination of R2 and R3 is in each case one row of table A Table 63 Compound 63.1 - 63.22: compounds of the formula Illf in which R1 is trifluoromethoxy and the combination of R2 and R3 is in each case one row of table A Table 64 Compound 64.1 - 64.22: compounds of the formula Illf in which R1 is cyano and the combination of R2 and R3 is in each case one row of table A Table 65 Compound 65.1 -65.22: compounds of the formula Illf in which R1 is nitro and the combination of R2 and R3 is in each case one row of table A Table 66 Compound 66.1 - 66.20: compounds of the formula Illf in which R1 is hydrogen and the combination of R2 and R3 is in each case one of rows 2 to 21 of table A Table A No. R2 R3 1 H CF3 2 F CF3 3 Cl CF3 4 Br CF3 5 I CF3 6 CH3 CF3 PF 56210 20 7 OCH3 CF3 8 CF3 CF3 9 OCF3 CF3 10 CN CF3 11 NO2 CF3 12 F CHF2 13 Cl CHF2 14 Br CHF2 15 I CHF2 16 CH3 CHF2 17 OCH3 CHF2 18 CF3 CHF2 19 OCF3 CHF2 20 CN CHF2 21 NO2 CHF2 22 H CHF2 A preferred embodiment of the mixtures according to the invention relates to the combination of the compound of the formula I and an active compound from the following groups: dithiocarbamates, in particular mancozeb, propineb, thiram, benzimidazole, in particular benomyl, thiophanate, carbendazim, dicarboximides, in particular iprodione, procymidone, vinclozolin, chlozolinate, phthalimides, in particular captan, chlorothalonil, folpet, anilinopyrimidines, in particular cyprodinil, pyrimethanil, mepanipyrim, triazoles, in particular tebuconazole, difenoconazole, cyproconazole, myclobutanil, carboxanilides, in particular fenhexamid, benalaxyl, boscalid, penthiopyrad, an anilide of the formula III, the compound of the formula IV, organochlorine compounds, in particular dichlofluanid, chlorothalonil, tolyfluanid, carbamate, in particular diethofencarb, nitrogen-containing heterocyclyl compounds, in particular fludioxonil, fluazinam, strobilurins, in particular kresoxim-methyl, pyraclostrobin, azoxystrobin, trifloxystrobin, enestroburin, picoxystrobin, fluoxastrobin, organotin compounds, in particular fentin acetyl, and, in particular 5-chloro-7-(4-methylpiperidin-1 -yl)-6-(2,4,6-trifluorophenyl)-[1,2,4]triazolo[1,5-a]pyri- midine. When preparing the mixtures, it is preferred to employ the pure active compounds, to which further active compounds against harmful fungi or against other pests, such as PF 56210 21 insects, arachnids or nematodes, or else herbicidal or growth-regulating active compounds or fertilizers can be added according to need as further active components. What is usually used are mixtures of the compound I with one active compound II. However, in certain cases, mixtures of the compound I with two or, if appropriate, a plurality of active components may be advantageous. Suitable further active components in the above sense are in particular the active compounds II mentioned at the outset and especially the preferred active compounds mentioned above. The compound I and the active compound II are usually applied in a weight ratio of from 100:1 to 1:100, preferably from 20:1 to 1:20, in particular from 10:1 to 1:10. The further active components are, if desired, added in a ratio of from 20:1 to 1:20 to the compound I. Depending on the type of compound and the desired effect, the application rates of the mixtures according to the invention are from 5 g/ha to 2000 g/ha, preferably from 50 to 900 g/ha, in particular from 50 to 750 g/ha. Correspondingly, the application rates for the compound I are generally from 1 to 1000 g/ha, preferably from 10 to 900 g/ha, in particular from 20 to 750 g/ha. Correspondingly, the application rates for the active compound II are generally from 1 to 2000 g/ha, preferably from 10 to 900 g/ha, in particular from 40 to 500 g/ha. In the treatment of seed, application rates of mixture are generally from 1 to 1000 g/100 kg of seed, preferably from 1 to 750 g/100 kg, in particular from 5 to 500g/100kg. The method for controlling harmful fungi is carried out by the separate or joint application of the compound I and the active compound II or of the mixtures of the compound I and the active compound II by spraying or dusting the seeds, the plants or the soil before or after sowing of the plants or before or after emergence of the plants. The mixtures according to the invention, or the compound I and the active compound II, can be converted into the customary formulations, for example solutions, emulsions, suspensions, dusts, powders, pastes and granules. The use form depends on the PF 56210 22 particular intended purpose; in each case, it should ensure a fine and even distribution of the compound according to the invention. The formulations are prepared in a known manner, for example by extending the active compound with solvents and/or carriers, if desired using emulsifiers and dispersants. Solvents/auxiliaries suitable for this purpose are essentially: water, aromatic solvents (for example Solvesso products, xylene), paraffins (for example mineral oil fractions), alcohols (for example methanol, butanol, pentanol, benzyl alcohol), ketones (for example cyclohexanone, gamma-butyrolactone), pyrrolidones (NMP, NOP), acetates (glycol diacetate), glycols, fatty acid dimethylamides, fatty acids and fatty acid esters. In principle, solvent mixtures may also be used, carriers such as ground natural minerals (for example kaolins, clays, talc, chalk) and ground synthetic minerals (for example highly disperse silicic acid, silicates); emulsifiers such as nonionogenic and anionic emulsifiers (for example polyoxyethylene fatty alcohol ethers, alkylsulfonates and arylsulfonates) and dispersants such as lignosulfite waste liquors and methylcellulose. Suitable for use as surfactants are alkali metal, alkaline earth metal and ammonium salts of lignosulfonic acid, naphthalenesulfonic acid, phenolsulfonic acid, dibutylnaphthalenesulfonic acid, alkylarylsulfonates, alkyl sulfates, alkylsulfonates, fatty alcohol sulfates, fatty acids and sulfated fatty alcohol glycol ethers, furthermore condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, condensates of naphthalene or of naphthalenesulfonic acid with phenol and formaldehyde, polyoxyethylene octylphenyl ether, ethoxylated isooctylphenol, octylphenol, nonylphenol, alkylphenyl polyglycol ethers, tributylphenyl polyglycol ether, tristearylphenyl polyglycol ether, alkylaryl polyether alcohols, alcohol and fatty alcohol ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ether acetal, sorbitol esters, lignosulfite waste liquors and methylcellulose. Substances which are suitable for the preparation of directly sprayable solutions, emulsions, pastes or oil dispersions are mineral oil fractions of medium to high boiling point, such as kerosene or diesel oil, furthermore coal tar oils and oils of vegetable or animal origin, aliphatic, cyclic and aromatic hydrocarbons, for example toluene, xylene, paraffin, tetrahydronaphthalene, alkylated naphthalenes or their derivatives, methanol, ethanol, propanol, butanol, cyclohexanol, cyclohexanone, isophorone, highly polar solvents, for example dimethyl sulfoxide, N-methylpyrrolidone and water. Powders, materials for spreading and dustable products can be prepared by mixing or PF 56210 23 concomitantly grinding the active substances with a solid carrier. Granules, for example coated granules, impregnated granules and homogeneous granules, can be prepared by binding the active compounds to solid carriers. Examples of solid carriers are mineral earths such as silica gels, silicates, talc, kaolin, attaclay, limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers, such as, for example, ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas, and products of vegetable origin, such as cereal meal, tree bark meal, wood meal and nutshell meal, cellulose powders and other solid carriers. In general, the formulations comprise from 0.01 to 95% by weight, preferably from 0.1 to 90% by weight, of the active compounds. The active compounds are employed in a purity of from 90% to 100%, preferably 95% to 100% (according to NMR spectrum). For the treatment of seed, the formulations in question give, after two- to ten-fold dilution, active compound concentrations of from 0.01 to 60% by weight, preferably from 0.1 to 40% by weight, in the ready-to-use preparations. The following are examples of formulations of the invention: 1. Products for dilution with water A Water-soluble concentrates (SL, LS) 10 parts by weight of the active compounds are dissolved with 90 parts by weight of water or a water-soluble solvent. As an alternative, wetters or other auxiliaries are added. The active compound dissolves upon dilution with water. In this way, a formulation having an active compound content of 10% by weight is obtained. B Dispersible concentrates (DC) 20 parts by weight of the active compounds are dissolved in 70 parts by weight of cyclohexanone with addition of 10 parts by weight of a dispersant, for example polyvinylpyrrolidone. Dilution with water gives a dispersion. The active compound content is 20% by weight. C Emulsifiable concentrates (EC) 15 parts by weight of the active compounds are dissolved in 75 parts by weight of xylene with addition of calcium dodecylbenzenesulfonate and castor oil ethoxylate (in each case 5 parts by weight). Dilution with water gives an emulsion. The formulation has an active compound content of 15% by weight. PF 56210 24 D Emulsions (EW, EO, ES) 25 parts by weight of the active compounds are dissolved in 35 parts by weight of xylene with addition of calcium dodecylbenzenesulfonate and castor oil ethoxylate (in each case 5 parts by weight). This mixture is added to 30 parts by weight of water by means of an emulsifying machine (for example Ultraturrax) and made into a homogeneous emulsion. Dilution with water gives an emulsion. The formulation has an active compound content of 25% by weight. E Suspensions (SC, OD, FS) In an agitated ball mill, 20 parts by weight of the active compounds are comminuted with addition of 10 parts by weight of dispersants and wetters and 70 parts by weight of water or an organic solvent to give a fine active compound suspension. Dilution with water gives a stable suspension of the active compound. The active compound content in the formulation is 20% by weight. F Water-dispersible granules and water-soluble granules (WG, SG) 50 parts by weight of the active compounds are ground finely with addition of 50 parts by weight of dispersants and wetters and prepared as water-dispersible or water- soluble granules by means of technical appliances (for example extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active compound. The formulation has an active compound content of 50% by weight. G Water-dispersible powders and water-soluble powders (WP, SP, SS, WS) 75 parts by weight of the active compounds are ground in a rotor-stator mill with addition of 25 parts by weight of dispersants, wetters and silica gel. Dilution with water gives a stable dispersion or solution of the active compound. The active compound content of the formulation is 75% by weight. H Gel formulations In a bead mill, 20 parts by weight of the active compounds, 10 parts by weight of dispersant, 1 part by weight of gelling agent and 70 parts by weight of water or an organic solvent are ground to give a fine suspension. Dilution with water gives a stable suspension having an active compound content of 20% by weight. 2. Products to be applied undiluted I Dusts (DP, DS) 5 parts by weight of the active compounds are ground finely and mixed intimately with 95 parts by weight of finely divided kaolin. This gives a dustable product having an active compound content of 5% by weight. PF 56210 25 J Granules (GR, FG, GG, MG) 0.5 part by weight of the active compounds is ground finely and associated with 99.5 parts by weight of carriers. Current methods are extrusion, spray-drying or the fluidized bed. This gives granules to be applied undiluted having an active compound content of 0.5% by weight. K ULV solutions (UL) 10 parts by weight of the active compounds are dissolved in 90 parts by weight of an organic solvent, for example xylene. This gives a product to be applied undiluted having an active compound content of 10% by weight. For seed treatment, it is customary to employ water-soluble concentrates (LS), suspensions (FS), dusts (DS), water-dispersible and water-soluble powders (WS, SS), emulsions (ES), emulsifiable concentrates (EC) and gel formulations (GF). These formulations can be applied to the seed undiluted or, preferably, diluted. Application can be prior to sowing. Preference is given to using FS formulations for seed treatment. Usually, such formulations comprise from 1 to 800 g of active compound/I, from 1 to 200 g of surfactants/I, from 0 to 200 g of antifreeze agents/I, from 0 to 400 g of binders/I, from 0 to 200 g of colorants/I and solvents, preferably water. The active compounds can be used as such, in the form of their formulations or the use forms prepared therefrom, for example in the form of directly sprayable solutions, powders, suspensions or dispersions, emulsions, oil dispersions, pastes, dustable products, materials for spreading, or granules, by means of spraying, atomizing, dusting, spreading or pouring. The use forms depend entirely on the intended purposes; they are intended to ensure in each case the finest possible distribution of the active compounds according to the invention. Aqueous use forms can be prepared from emulsion concentrates, pastes or wettable powders (sprayable powders, oil dispersions) by adding water. To prepare emulsions, pastes or oil dispersions, the substances, as such or dissolved in an oil or solvent, can be homogenized in water by means of a wetter, tackifier, dispersant or emulsifier. However, it is also possible to prepare concentrates composed of active substance, wetter, tackifier, dispersant or emulsifier and, if appropriate, solvent or oil, with these concentrates being suitable for dilution with water. The active compound concentrations in the ready-to-use preparations can be varied PF 56210 26 within relatively wide ranges. In general, they are from 0.0001 to 10%, preferably from 0.01 to 1%. The active compounds may also be used successfully in the ultra-low-volume process (ULV), it being possible to apply formulations comprising over 95% by weight of active compound, or even to apply the active compound without additives. Oils of various types, wetters, adjuvants, herbicides, fungicides, other pesticides, or bactericides may be added to the active compounds even, if appropriate, not until immediately prior to use (tank mix). These agents can be admixed with the compositions according to the invention in a weight ratio of from 1:100 to 100:1, preferably from 1:10 to 10:1. Suitable adjuvants in this context are in particular: organic modified polysiloxanes, for example Break Thru S 240®; alcohol alkoxylates, for example Atplus 245®, Atplus MBA 1303®, Plurafac LF 300® and Lutensol ON 30®; EO/PO block polymers, for example Pluronic RPE 2035® and Genapol B®; alcohol ethoxylates, for example Lutensol XP 80®; and sodium dioctylsulfosuccinate, for example Leophen RA®. The compounds I and II or the mixtures or the corresponding formulations are applied by treating the harmful fungi, and the plants, seeds, soils, areas, materials or spaces to be kept free from them, with a fungicidally effective amount of the mixture or, in the case of separate application, of the compounds I and II. Application can be carried out before or after infection by the harmful fungi. The fungicidal effect of the compound and the mixtures can be demonstrated by the following tests: The active compounds were separately or jointly prepared as a stock solution comprising 25 mg of active compound which was made up to 10 ml using a mixture of acetone and/or DMSO and the emulsifier Uniperol® EL (wetting agent having emulsifying and dispersing action based on ethoxylated alkylphenols) in a volume ratio of soivent/emulsifier of 99 to 1. The mixture was then made up with water to 100 ml. This stock solution was diluted with the solvent/emulsifier/water mixture described to the concentration of active compounds stated below. The visually determined percentages of infected leaf areas were converted into efficacies in % of the untreated control: The efficacy (E) is calculated as follows using Abbot's formula: PF 56210 27 E = (1 -a/b) • 100 a corresponds to the fungal infection of the treated plants in % and P corresponds to the fungal infection of the untreated (control) plants in % An efficacy of 0 means that the infection level of the treated plants corresponds to that of the untreated control plants; an efficacy of 100 means that the treated plants were not infected. The expected efficacies of combinations of active compounds were determined using Colby's formula (Colby, S.R. "Calculating synergistic and antagonistic responses of herbicide combinations", Weeds, 15, 20-22, 1967) and compared with the observed efficacies. Colby's formula: E = x + y-x-y/100 E expected efficacy, expressed in % of the untreated control, when using the mixture of the active compounds A and B at the concentrations a and b x efficacy, expressed in % of the untreated control, when using the active compound A at the concentration a y efficacy, expressed in % of the untreated control, when using the active compound B at the concentration b Greenhouse experiments Use example 1 - activity against Botrytis cinerea on bell peppers Bell pepper seedlings of the cultivar "Neusiedler Ideal Elite" were, after 2-3 leaves were well developed, sprayed to runoff point with an aqueous suspension in the active compound concentration stated below. The next day, the treated plants were inoculated with a spore suspension of Botrytis cinerea which comprised 1.7 x 106 spores/ml in a 2% strength biomalt solution. The test plants were then placed in a dark climatized chamber at 22 to 24°C and high atmospheric humidity. After 5 days, the extent of the fungal infection on the leaves could be determined visually in %. PF 56210 28 No. Activecompound Cone,[ppm] Ratio Observedactivity (%) Activity calculatedaccording to Colby (%) 1 - (control) - 0(100%infection) 2 I-B 6316 2010 3 dithianon (F11) 63 10 4 I-B + F11 63 + 63 1 :1 60 28 5 I-B + F11 16 + 63 1 :4 50 19 Use example 2 - curative activity against brown rust of wheat caused by Puccinia recondita Leaves of wheat seedlings of the cultivar "Kanzler" cultivated in pots were inoculated with a spore suspension of brown rust (Puccinia recondita). The pots were then placed in a chamber with high atmospheric humidity (90 to 95%) and at 20 to 22°C for 24 hours. During this time, the spores germinated and the germ tubes penetrated into leaf tissue. The next day, the infected plants were sprayed to runoff point with the solution of active compound described above having the active compound concentration stated below. After the spray coating had dried on, the test plants were cultivated in a greenhouse at temperatures between 20 and 22°C and at 65 to 70% relative atmospheric humidity for 7 days. The extent of the rust fungus development on the leaves was then determined. No. Activecompound Cone,[ppm] Ratio Observedactivity (%) Activity calculatedaccording to Colby(%) 6 - (control) - 0 (85%infection) 7 I-B 16 6 8 kresoxim-methyl (B5) 634 180 9 boscalid (C3) 16 0 10 metalaxyl (C8) 16 0 11 dimethomorph(C17) 82 00 12 I-B + B5 16 + 63 1 :4 99 22 13 I-B + C3 16 + 16 1 : 1 82 6 14 I-B + C8 16 + 16 1 : 1 94 6 15 I-B + C17 16 + 8 2: 1 92 6 16 I-B + C17 16+2 8 : 1 76 6 PF 56210 29 Microtiter tests The active compounds were formulated separately in DMSO as a stock solution having a concentration of 10 000 ppm. Fluazinam and epoxiconazole were used as commercial formulations and diluted with water to give a 10 000 ppm stock solution. The measured parameters were compared to the growth of the active compound-free control variant and the fungus- and active compound-free blank value to determine the relative growth in % of the pathogens in the individual active compounds. Use example 3 - activity against the late blight pathogen Phytophthora infestans in the microtiter test The stock solution is pipetted into a microtiter piate (MTP) and diluted with a pea juice- based aqueous fungus nutrient medium to the stated active compound concentration. An aqueous zoospore suspension of Phytophthora infestans was then added. The plates were placed in a water vapor-saturated chamber at temperatures of 18°C. Using an absorption photometer, the MTPs were measured at 405 nm on day 7 after the inoculation. No. Activecompound Cone,[ppm] Ratio Observedactivity (%) Activity calculatedaccording to Colby(%) 17 I-B 12532840.25 57352754 18 epoxiconazole(A7) 12532 319 19 prothioconazole(A19) 328 460 20 kresoxim-methyl (B5) 1 36 21 fluazinam (D1) 1 0 22 I-B + A7 125 + 32 4: 1 73 61 23 I-B + A7 32 + 125 1 :4 88 55 24 I-B + A19 32 + 8 4: 1 47 35 25 I-B + A19 8 + 32 1 :4 77 60 26 I-B + B5 4 + 1 4:1 65 39 PF 56210 30 No. Activecompound Cone.[PPm] Ratio Observedactivity (%) Activity calculatedaccording to Colby(%) 27 I-B + B5 0.25 + 1 1 :4 53 38 28 I-B + D1 4 + 1 4:1 92 5 29 I-B + D1 0.25 + 1 1 :4 41 5 Use example 4 - activity against the gray mold pathogen Botrytis cinerea in the microtiter test The stock solution was pipetted into a microtiter plate (MTP) and diluted with a malt- based aqueous fungus nutrient medium to the stated active compound concentration. An aqueous spore suspension of Botrytis cinerea was then added. The plates were placed in a water vapor-saturated chamber at temperatures of 18°C. Using an absorption photometer, the MTPs were measured at 405 nm on day 7 after the inoculation. No. Activecompound Cone,[ppm] Ratio Observedactivity (%) Activity calculatedaccording to Colby(%) 30 I-B 410.25 67402 31 epoxiconazole(A7) 1 2 32 cyazofamid(A30) 1 00 33 pyraclostrobin(B8) 0.25 20 34 mancozeb (E1) 4 9 35 I-B + A7 1 + 1 1 :1 67 41 36 I-B + A30 1 + 0.25 4:1 58 40 37 I-B + A30 1 +4 1 :4 100 40 38 I-B + B8 0.25 + 0.25 1 :1 55 22 39 I-B + E1 4 + 4 1 :1 97 70 The test results show that, by virtue of the synergism, the mixtures according to the invention are considerably more active than had been predicted using Colby's formula. PF 56210 31 We claim: 1. A fungicidal mixture for controlling phytopathogenic harmful fungi, which mixture comprises two active components: 1) carbamate oxime ethers of the formula I. 2) at least one active compound II selected from the following groups: A) azoles, such as bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, enilconazol, epoxiconazole, fluquinconazole, fenbuconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, metconazole, myclobutanil, penconazole, propiconazole, prothioconazole, simeconazoie, triadi- mefon, triadimenol, tebuconazole, tetraconazole, triticonazole, prochloraz, pefurazoate, imazalil, triflumizole, cyazofamid, benomyl, carbendazim, thiabendazole, fuberidazole, ethaboxam, etridiazole, hymexazole, B) strobilurins, such as azoxystrobin, dimoxystrobin, enestroburin, fluoxastrobin, kresoxim-methyl, metominostrobin, orysastrobin, picoxystrobin, pyraclostrobin, trifloxystrobin; C) carboxamides, such as carboxin, benalaxyl, boscalid, fenhexamid, flutolanil, furametpyr, mepronil, metalaxyl, mefenoxam, ofurace, oxadixyl, oxycarboxin, penthiopyrad, thifluzamide, tiadinil, 3,4-dichloro-N-(2-cyanophenyl)isothiazole-5-carboxamide, dimethomorph, flumorph, flumetover, fluopicolide (picobenzamid), zoxamide, carpropamid, diclocymet, mandipropamid, N-(2-{4-[3-(4-chlorophenyl)prop-2-ynyloxy]-3-methoxyphenyl}ethyl)-2- methanesulfonylamino-3-methylbutyramide, N-(2-{4-[3-(4-chlorophenyl)prop-2-ynyloxy]-3-methoxyphenyl}ethyl)-2- ethanesulfonylamino-3-methylbutyramide, PF 56210 32 amides of the formula III, in which the variables and the index are as defined below: R1 and R2 independently of one another are hydrogen, halogen, d- C6-alkyl or d-C6 haloalkyl, cyano, nitro, methoxy or trifluoromethoxy, with the proviso that R1 and R2 are not simultaneously hydrogen, and R3 is CF3 or CHF2; D) heterocyclic compounds, such as fluazinam, pyrifenox, bupirimate, cyprodinil, fenarimol, ferimzone, mepanipyrim, nuarimol, pyrimethanil, triforine, fenpiclonil, fludioxonil, aldimorph, dodemorph, fenpropimorph, tridemorph, fenpropidin, iprodione, procymidone, vinclozolin, famoxadone, fenamidone, octhilinone, probenazole, 5-chloro-7-(4-methylpiperidin-1-yl)-6-(2,4,6-trifluorophenyl)-[1,2,4]tri- azolo[1,5-a]pyrimidine, anilazine, diclomezine, pyroquilon, proquinazid, tricyclazole, 2-butoxy-6-iodo-3-propylchromen-4-one acibenzolar-S-methyl, captafol, captan, dazomet, folpet, fenoxanil, quinoxyfen, or N,N-dimethyl-3-(3-bromo-6-fluoro-2-methylindole-1-sulfonyl)- [1,2,4]triazole-1-sulfonamide; E) carbamates, such as mancozeb, maneb, metam, metiram, ferbam, propineb, thiram, zineb, ziram, diethofencarb, iprovalicarb, flubenthiavalicarb, propamocarb, methyl 3-(4-chlorophenyl)-3-(2-isopropoxycarbonylamino-3-methyl- butyrylamino)propanoate, F) other fungicides, selected from the group consisting of guanidines: dodine, iminoctadine, guazatine, PF 56210 33 antibiotics: kasugamycin, streptomycin, polyoxine, validamycin A, nitrophenyl derivatives: binapacryl, dinocap, dinobuton, sulfur-containing heterocyclyl compounds: dithianon, isoprothiolane, organometallic compounds: fentin salts, such as fentin acetate, organophosphorus compounds: edifenphos, iprobenfos, fosetyl, fosetyl aluminum, phosphorous acid and its salts, pyrazophos, tolclofos-methyl, organochlorine compounds: chlorothalonil, dichlofluanid, flusulfamide, hexachlorobenzene, phthalide, pencycuron, quintozene, thiophanate- methyl, tolylfluanid, inorganic active compounds: Bordeaux mixture, copper acetate, copper hydroxide, copper oxychloride, basic copper sulfate, sulfur, others: cyflufenamid, cymoxanil, dimethirimol, ethirimol, furalaxyl, metrafenone and spiroxamine, in a synergistically effective amount. The fungicidal mixture according to claim 1, which comprises, as carbamate oxime ether of the formula I, the compound I-B 2. The fungicidal mixture according to claim 1, which comprises, as carbamate oxime ether of the formula I, the compound I-A 4. The fungicidal mixture according to any of claims 1 to 3 which comprises the compound of the formula I and the compound of the formula II in a weight ratio of from 100:1 to 1:100. 5. A composition comprising a liquid or solid carrier and a mixture according to any of claims 1 to 4. 6. A method for controlling phytopathogenic harmful fungi which comprises treating the fungi, their habitat or the seed, the soil or the plants to be protected against PF 56210 34 fungal attack with an effective amount of the compound I and the compound II according to claim 1. 7. The method according to claim 6, wherein the compounds I and II according to claim 1 are applied simultaneously, that is jointly or separately, or in succession. 8. The method according to claim 6 or 7, wherein the compounds I and II according to claim 1 or the mixture according to any of claims 1 to 3 are/is applied in an amount of from 5 g/ha to 2000 g/ha. 9. The method according to claim 6 or 7, wherein the compounds I and II according to claim 1 or the mixture according to any of claims 1 to 4 are/is applied in an amount of from 1 to 1000 g/100 kg of seed. 10. Seed comprising the mixture according to any of claims 1 to 4 in an amount of from 1 to 1000 g/100 kg. 11. The use of the compounds I and II according to claim 1 for preparing a composition suitable for controlling harmful fungi. Fungicidal mixtures, comprising as active components 1) carbamate oxime ethers of the formula I, in which X is N or CH, and 2) at least one active compound II selected from the group of the azoles, stro- bilurins, carboxamides, heterocyclic compounds, carbamates, guanidines, antibiotics, nitrophenyl derivatives, sulfur-containing heterocyclyl com- pounds, organometallic compounds, organophosphorus compounds, or- ganochlorine compounds, inorganic active compounds, cyflufenamid, cy- moxanil, dimethirimol, ethirimol, furalaxyl, metrafenone and spiroxamine, in a synergistically effective amount, methods for controlling harmful fungi using mix- tures of the compound I with active compounds II, the use of the compound I with ac- tive compounds II for preparing such mixtures and compositions comprising these mix- tures. |
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02040-kolnp-2007-correspondence others 1.1.pdf
02040-kolnp-2007-correspondence others 1.2.pdf
02040-kolnp-2007-correspondence others.pdf
02040-kolnp-2007-description complete.pdf
02040-kolnp-2007-form 3 1.1.pdf
02040-kolnp-2007-form 5 1.1.pdf
02040-kolnp-2007-pct request form.pdf
02040-kolnp-2007-priority document.pdf
2040-KOLNP-2007-AMANDED CLAIMS.pdf
2040-KOLNP-2007-CANCELLED PAGES.pdf
2040-KOLNP-2007-CORRESPONDENCE OTHERS 1.3.pdf
2040-KOLNP-2007-DESCRIPTION (COMPLETE).pdf
2040-KOLNP-2007-FORM 3-1.2.pdf
2040-KOLNP-2007-FORM 5-1.2.pdf
2040-KOLNP-2007-PETITION UNDER RULE 137.pdf
2040-KOLNP-2007-REPLY TO EXAMINATION REPORT.pdf
Patent Number | 242543 | ||||||||||||
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Indian Patent Application Number | 2040/KOLNP/2007 | ||||||||||||
PG Journal Number | 36/2010 | ||||||||||||
Publication Date | 03-Sep-2010 | ||||||||||||
Grant Date | 31-Aug-2010 | ||||||||||||
Date of Filing | 05-Jun-2007 | ||||||||||||
Name of Patentee | BASF AKTIENGESELLSCHAFT | ||||||||||||
Applicant Address | 67056 LUDWIGSHAFEN | ||||||||||||
Inventors:
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PCT International Classification Number | A01N 47/12 | ||||||||||||
PCT International Application Number | PCT/EP2005/013816 | ||||||||||||
PCT International Filing date | 2005-12-21 | ||||||||||||
PCT Conventions:
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