| Title of Invention | AMYLOID B(1-42) OLIGOMERS, DERIVATIVES THEREOF AND ANTIBODIES THERETO, METHODS OF PREPARATION THEREOF |
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| Abstract | The invention relates to neuromodulatory oligomers of the amyloid-$g(b)(1-42) protein, a particular production method, by means of which the oligomer can be obtained in a reproducible manner at high yield, the use of the oligomers as diagnostic and therapeutics agents, for the generation of oligomer-specific antibodies and for the discovery of substances which can interact with the oligomers and in the formation thereof. Corresponding methods for the production of the antibodies and for discovery of the substances are also disclosed as are the antibodies themselves and the use of the antibodies or substances as diagnostic and therapeutic agents. The invention further relates to derivatives of the oligomers and oligomers based on abbreviated forms of the amyloid-beta(1-42) proteins, the production and use thereof. |
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1728-CHENP-2005 CORRESPONDENCE OTHERS.pdf
1728-CHENP-2005 CORRESPONDENCE PO.pdf
1728-CHENP-2005 DESCRIPTION (COMPLETE).pdf
1728-CHENP-2005 POWER OF ATTORNEY.pdf
| Patent Number | 238777 | ||||||||||||||||||
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| Indian Patent Application Number | 1728/CHENP/2005 | ||||||||||||||||||
| PG Journal Number | 9/2010 | ||||||||||||||||||
| Publication Date | 26-Feb-2010 | ||||||||||||||||||
| Grant Date | 19-Feb-2010 | ||||||||||||||||||
| Date of Filing | 28-Jul-2005 | ||||||||||||||||||
| Name of Patentee | ABBOTT GMBH & CO. KG | ||||||||||||||||||
| Applicant Address | Max-Planck-Ring 2, 65205 Wiesbaden | ||||||||||||||||||
Inventors:
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| PCT International Classification Number | C07K 14/47 | ||||||||||||||||||
| PCT International Application Number | PCT/EP2004/000927 | ||||||||||||||||||
| PCT International Filing date | 2004-02-02 | ||||||||||||||||||
PCT Conventions:
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