Title of Invention

A PROCESS FOR PREPARATION OF RABIES VACCINE

Abstract The present invention discloses a novel process of preparation of rabies vaccine. The process includes multiplying Rabies virus on Human diploid cells such as MRC-5. The Human diploid cells were grown on microcarriers and grown cells infected on with rabies virus seed. The multiplication of rabies virus is effected in serum free medium and thus released virus into the medium is harvested and purified by two step column chromatography to effect concentration, purification of virus. The purifies virus suspended in a suitable buffer is then inactivated by beta-propiolactone. The inactivated virus retains antigenic properties for eliciting immune response against rabies virus. This process result in high concentration and purity. The In-process quantification of Virus and antigen are done by analytical gel filtration chromatography.
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Documents:

46-MUM-2005-ABSTRACT(16-1-2006).pdf

46-MUM-2005-ABSTRACT(21-4-2009).pdf

46-mum-2005-abstract(complete)-(21-4-2009).pdf

46-mum-2005-abstract(granted)-(25-8-2009).pdf

46-mum-2005-abstract(provisional)-(17-1-2005).pdf

46-MUM-2005-CLAIMS(17-12-2008).pdf

46-MUM-2005-CLAIMS(21-4-2009).pdf

46-mum-2005-claims(amanded)-(21-4-2009).pdf

46-MUM-2005-CLAIMS(CANCELLED PAGE)-(17-12-2008).pdf

46-MUM-2005-CLAIMS(CANCELLED PAGES)-(21-4-2009).pdf

46-mum-2005-claims(complete)-(21-4-2009).pdf

46-mum-2005-claims(granted)-(25-8-2009).pdf

46-MUM-2005-CLAIMS(MARKED COPY)-(17-12-2008).pdf

46-MUM-2005-CORRESPONDENCE (18-08-2008).pdf

46-mum-2005-correspondence(10-8-2005).pdf

46-mum-2005-correspondence(13-4-2009).pdf

46-MUM-2005-CORRESPONDENCE(17-12-2008).pdf

46-MUM-2005-CORRESPONDENCE(21-4-2009).pdf

46-mum-2005-correspondence(ipo)-(26-8-2009).pdf

46-MUM-2005-DESCRIPTION(COMPLETE)-(17-12-2008).pdf

46-MUM-2005-DESCRIPTION(COMPLETE)-(21-4-2009).pdf

46-mum-2005-description(granted)-(25-8-2009).pdf

46-mum-2005-description(provisional)-(17-1-2005).pdf

46-MUM-2005-DRAWING(16-1-2006).pdf

46-MUM-2005-DRAWING(21-4-2009).pdf

46-mum-2005-drawing(complete)-(21-4-2009).pdf

46-mum-2005-drawing(granted)-(25-8-2009).pdf

46-MUM-2005-FORM 1(17-1-2005).pdf

46-MUM-2005-FORM 1(21-4-2009).pdf

46-mum-2005-form 18(10-8-2006).pdf

46-mum-2005-form 2(17-12-2008).pdf

46-mum-2005-form 2(21-4-2009).pdf

46-mum-2005-form 2(complete)-(21-4-2009).pdf

46-mum-2005-form 2(granted)-(25-8-2009).pdf

46-mum-2005-form 2(provisional)-(17-1-2005).pdf

46-MUM-2005-FORM 2(TITLE PAGE)-(17-12-2008).pdf

46-MUM-2005-FORM 2(TITLE PAGE)-(21-4-2009).pdf

46-mum-2005-form 2(title page)-(complete)-(21-4-2009).pdf

46-mum-2005-form 2(title page)-(granted)-(25-8-2009).pdf

46-mum-2005-form 2(title page)-(provisional)-(17-1-2005).pdf

46-mum-2005-form 3(17-1-2005).pdf

46-mum-2005-form 5(16-1-2006).pdf

46-mum-2005-form 5(17-1-2005).pdf

46-mum-2005-marked copy(21-4-2009).pdf

46-MUM-2005-POWER OF ATTORNEY (18-08-2008).pdf

46-MUM-2005-POWER OF ATTORNEY(17-12-2008).pdf


Patent Number 235769
Indian Patent Application Number 46/MUM/2005
PG Journal Number 36/2009
Publication Date 04-Sep-2009
Grant Date 25-Aug-2009
Date of Filing 17-Jan-2005
Name of Patentee SERUM INSTITUTE OF INDIA LIMITED
Applicant Address SAROSH BHAVAN, 16-B/1, DR. AMBEDKAR ROAD, PUNE-411001.
Inventors:
# Inventor's Name Inventor's Address
1 CYRUS S POONAWALLA 11, GIDNEY PARK, PUNE 411037.
2 SUBHASH V. KAPRE GOLDEN BLOSSOM, FLAT NO.7, 8&9, 3rd FLOOR, KANCHAN GALLI, OFF LAW COLLEGE ROAD, PUNE-411004.
PCT International Classification Number C07K14/145A61K39/20
PCT International Application Number N/A
PCT International Filing date
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 NA