Title of Invention | A PROCESS FOR PREPARATION OF RABIES VACCINE |
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Abstract | The present invention discloses a novel process of preparation of rabies vaccine. The process includes multiplying Rabies virus on Human diploid cells such as MRC-5. The Human diploid cells were grown on microcarriers and grown cells infected on with rabies virus seed. The multiplication of rabies virus is effected in serum free medium and thus released virus into the medium is harvested and purified by two step column chromatography to effect concentration, purification of virus. The purifies virus suspended in a suitable buffer is then inactivated by beta-propiolactone. The inactivated virus retains antigenic properties for eliciting immune response against rabies virus. This process result in high concentration and purity. The In-process quantification of Virus and antigen are done by analytical gel filtration chromatography. |
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46-MUM-2005-ABSTRACT(16-1-2006).pdf
46-MUM-2005-ABSTRACT(21-4-2009).pdf
46-mum-2005-abstract(complete)-(21-4-2009).pdf
46-mum-2005-abstract(granted)-(25-8-2009).pdf
46-mum-2005-abstract(provisional)-(17-1-2005).pdf
46-MUM-2005-CLAIMS(17-12-2008).pdf
46-MUM-2005-CLAIMS(21-4-2009).pdf
46-mum-2005-claims(amanded)-(21-4-2009).pdf
46-MUM-2005-CLAIMS(CANCELLED PAGE)-(17-12-2008).pdf
46-MUM-2005-CLAIMS(CANCELLED PAGES)-(21-4-2009).pdf
46-mum-2005-claims(complete)-(21-4-2009).pdf
46-mum-2005-claims(granted)-(25-8-2009).pdf
46-MUM-2005-CLAIMS(MARKED COPY)-(17-12-2008).pdf
46-MUM-2005-CORRESPONDENCE (18-08-2008).pdf
46-mum-2005-correspondence(10-8-2005).pdf
46-mum-2005-correspondence(13-4-2009).pdf
46-MUM-2005-CORRESPONDENCE(17-12-2008).pdf
46-MUM-2005-CORRESPONDENCE(21-4-2009).pdf
46-mum-2005-correspondence(ipo)-(26-8-2009).pdf
46-MUM-2005-DESCRIPTION(COMPLETE)-(17-12-2008).pdf
46-MUM-2005-DESCRIPTION(COMPLETE)-(21-4-2009).pdf
46-mum-2005-description(granted)-(25-8-2009).pdf
46-mum-2005-description(provisional)-(17-1-2005).pdf
46-MUM-2005-DRAWING(16-1-2006).pdf
46-MUM-2005-DRAWING(21-4-2009).pdf
46-mum-2005-drawing(complete)-(21-4-2009).pdf
46-mum-2005-drawing(granted)-(25-8-2009).pdf
46-MUM-2005-FORM 1(17-1-2005).pdf
46-MUM-2005-FORM 1(21-4-2009).pdf
46-mum-2005-form 18(10-8-2006).pdf
46-mum-2005-form 2(17-12-2008).pdf
46-mum-2005-form 2(21-4-2009).pdf
46-mum-2005-form 2(complete)-(21-4-2009).pdf
46-mum-2005-form 2(granted)-(25-8-2009).pdf
46-mum-2005-form 2(provisional)-(17-1-2005).pdf
46-MUM-2005-FORM 2(TITLE PAGE)-(17-12-2008).pdf
46-MUM-2005-FORM 2(TITLE PAGE)-(21-4-2009).pdf
46-mum-2005-form 2(title page)-(complete)-(21-4-2009).pdf
46-mum-2005-form 2(title page)-(granted)-(25-8-2009).pdf
46-mum-2005-form 2(title page)-(provisional)-(17-1-2005).pdf
46-mum-2005-form 3(17-1-2005).pdf
46-mum-2005-form 5(16-1-2006).pdf
46-mum-2005-form 5(17-1-2005).pdf
46-mum-2005-marked copy(21-4-2009).pdf
46-MUM-2005-POWER OF ATTORNEY (18-08-2008).pdf
46-MUM-2005-POWER OF ATTORNEY(17-12-2008).pdf
Patent Number | 235769 | |||||||||
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Indian Patent Application Number | 46/MUM/2005 | |||||||||
PG Journal Number | 36/2009 | |||||||||
Publication Date | 04-Sep-2009 | |||||||||
Grant Date | 25-Aug-2009 | |||||||||
Date of Filing | 17-Jan-2005 | |||||||||
Name of Patentee | SERUM INSTITUTE OF INDIA LIMITED | |||||||||
Applicant Address | SAROSH BHAVAN, 16-B/1, DR. AMBEDKAR ROAD, PUNE-411001. | |||||||||
Inventors:
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PCT International Classification Number | C07K14/145A61K39/20 | |||||||||
PCT International Application Number | N/A | |||||||||
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PCT Conventions:
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