| Title of Invention |
BENZIMIDAZOLE-2-CARBOXYLIC AMIDES AS FACTOR Xa INHIBITORS |
| Abstract |
The present invention relates to compounds of the formula (I), wherein R<0,>, R<1> , R<2>, Q, V, G and M have the meanings indicated in the claims. The compounds of the formula I are valuable pharmacologically active compounds. They exhibit a strong antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses. They are reversible inhibitors of the blood clotting enzymes factor Xa (FXa) and/or factor VIIa (FVIIa), and can in general be applied in conditions in which an undesired activity of factor Xa and/or factor VIIa is present or for the cure or prevention of which an inhibition of factor Xa and/or factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of the formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations. |
Documents:
3058-CHENP-2005 ABSTRACT.pdf
3058-CHENP-2005 CLAIMS.pdf
3058-CHENP-2005 CORRESPONDENCE OTHERS.pdf
3058-CHENP-2005 CORRESPONDENCE PO.pdf
3058-CHENP-2005 DESCRIPTION (COMPLETE).pdf
3058-CHENP-2005 FORM 1.pdf
3058-CHENP-2005 FORM 18.pdf
3058-CHENP-2005 FORM 3.pdf
3058-CHENP-2005 FORM 5.pdf
3058-CHENP-2005 PCT.pdf
3058-CHENP-2005 PETITIONS.pdf
3058-CHENP-2005 POWER OF ATTORNEY.pdf