Title of Invention

HUMAN MONOCLONAL ANTIBODIES TO PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA)

Abstract This invention relates to recombinant human monoclonal antibodies which bind to PSMA and related antibody-based compositions aqnd molecules, are disclosed. The human antibodies can be produced in a nonhuman transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, nonhuman transgenic animals and hybridomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies
Full Text

Documents:

1908-chenp-2004 abstract.pdf

1908-chenp-2004 claims.pdf

1908-chenp-2004 correspondence others.pdf

1908-chenp-2004 correspondence po.pdf

1908-chenp-2004 description (complete).pdf

1908-chenp-2004 drawings.pdf

1908-chenp-2004 form 1.pdf

1908-chenp-2004 form 13.pdf

1908-chenp-2004 form 18.pdf

1908-chenp-2004 form 3.pdf

1908-chenp-2004 form 5.pdf

1908-chenp-2004 pct.pdf

1908-chenp-2004 petition.pdf

1908-chenp-2004 power of attorney.pdf


Patent Number 234659
Indian Patent Application Number 1908/CHENP/2004
PG Journal Number 29/2009
Publication Date 17-Jul-2009
Grant Date 10-Jun-2009
Date of Filing 26-Aug-2004
Name of Patentee MEDAREX, INC.
Applicant Address 707 State Road, Princeton, NJ 08540
Inventors:
# Inventor's Name Inventor's Address
1 DEO, Yashwant, M. 35 Cortland Drive, East Brunswick, NJ 08816
2 GRAZIANO, Robert 26 Kingsridge Road, Frenchtown, NJ 08825
3 HUDSON, Debra 2380 Tuscany Circle, Livermore, CA 94550
4 HOLMES, Eric, H. 4116 212th Street SE, Bothell, WA 98021
5 TINO, William, T. 16115 NE 106th Street, Redmond, WA 98052
6 BLACK, Amelia 124 Capistrano Place, Los Gatos, CA 95035
PCT International Classification Number C12N
PCT International Application Number PCT/US2003/02448
PCT International Filing date 2003-01-28
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 10/059,989 2002-01-28 U.S.A.