Title of Invention	"AN ANTI-INFLAMMATORY, ANTIARTHRITIC AND A VASCULODILATOR HERBAL OIL FROM MOMORDICA CHARANTIA L. (BITTER GOURD)"
Abstract	This invention relates to the manufacture of a herbal oil. This particularly relates to an effective inflammatory, antiarthritic, a vasculodilator and a pain relieving herbal oil from seeds of Various oils are commercially available in the market with their different therapeutical values. But there is a great dearth of an oil which is an antiinflammatory, antiarthritic and a vasculodilator. So far there is no mention in the literature of the efficacy of this herbal oil from bitter gourd.

Title of Invention

"AN ANTI-INFLAMMATORY, ANTIARTHRITIC AND A VASCULODILATOR HERBAL OIL FROM MOMORDICA CHARANTIA L. (BITTER GOURD)"

Abstract

Full Text	This invention relates to the manufacture of a herbal oil. This particularly relates to an effective inflammatory, antiarthritic, a vasculodilator and a pain relieving herbal oil from seeds of Momordica charantia L., (bitter gourd) Various oils are commercially available in the market with their different therapeutical values. But there is a great dearth of an oil which is an antiinflammatory, antiarthritic and a vasculodilator. So far there is no mention in the literature of the efficacy of this herbal oil from bitter gourd. Accordingly the present invention provides a method for manufacturing of an antiinflammatory, antiarthritic and vasculodilator herbal oil from the seeds of Momordica charantia L.. (bitter gourd) which comprises treating he dried seed powder with sulfuric acid, separating the residual mass containing the oil and then extracting this layer with hexane followed by ether to obtain the said herbal oil and if desired purifying the said herbal oil by conventional method. In another embodiment of this invention, the seeds of bitter gourd can be dried and powdered prior to sulfuric acid treatment which can be done by any known manner. The oil thus obtained by known method was put on a column of Gas liquid Chromatogram for analysis of its fatty acid contents. When this oil was externally applied on patients suffering from muscular pain, gangrene wounds or arthritic, gave great relief. The following typical example is given to illustrate the invention. EXAMPLE I The 100 g seeds of Momordica charantia L.. (bitter gourd) collected from the field were splitted, crushed and powdered. The seed powder was treated with 0.1 of 25 ml of sulfuric acid. The mixture after 5-10 min. was filtered and the residue was extracted with hexane and either in succession. The oil thus obtained measured to 20-25%. The oil was purified further for chemical analysis using Gas Liquid chromatogram which showed the presence of 7 fatty acids as: 1. Capric acid (0.9%) 2. Laurie acid (0.8%) 3. Palmitic acid (4.2%) 4. Stearic acid (60.90%) 5. Oleic acid (13.30%) 6. Archidic acid (3.20%) 7. Linoleic acid (9.80%) 8. Other undetected minor acids (6.90%) The Stearic acid was maximum in amount followed by Oleic acid, linoleic acid and others. When this oil was applied externally on about 100 patients suffering from muscular pain/ inflammation/ arthritis/ old wounds as gangrene, showed antiinflammatory, pain relieving and vasculodialatory properties and felt relieved. The invention as described above and particularly in Example I as nearly an illustrated in nature and in no way it should be construed to limit the scope of the invention. Further modifications are possible without departing from the soul of the invention. I CLAIM 1. An anti-inflammatory, ant arthritic and a vasculodilator herbal oil from seeds of Momordica charantia L., (bitter gourd) obtained by the process which comprises the treatment of seeds of Momordica charantia L., (bitter gourd) with dilute sulfuric acid followed by the extraction with hexane and either in succession. 2. An oil as claimed in claim I wherein the seeds are preferably crushed, powdered before treatment with sulfuric acid. 3. An oil, as claimed in claim I, is anti-inflammatory, antiarthritic, vasculodilator and a wound healer substantially as herein - before described with reference to any of the foregoing example. 4. JP 3092116 (9/04/1990) Method for producing bitter taste removed piece or powder of monostich charities. 5. IN S1887 (16/08/1995) A process for the isolation of blood sugar dowering active principle form the fricative of memories charantia .

Full Text

This invention relates to the manufacture of a herbal oil. This particularly relates to an effective inflammatory, antiarthritic, a vasculodilator and a pain relieving herbal oil from seeds of Momordica charantia L., (bitter gourd)
Various oils are commercially available in the market with their different therapeutical values. But there is a great dearth of an oil which is an antiinflammatory, antiarthritic and a vasculodilator. So far there is no mention in the literature of the efficacy of this herbal oil from bitter gourd.
Accordingly the present invention provides a method for manufacturing of an antiinflammatory, antiarthritic and vasculodilator herbal oil from the seeds of Momordica charantia L.. (bitter gourd) which comprises treating he dried seed powder with sulfuric acid, separating the residual mass containing the oil and then extracting this layer with hexane followed by ether to obtain the said herbal oil and if desired purifying the said herbal oil by conventional method.
In another embodiment of this invention, the seeds of bitter gourd can be dried and powdered prior to sulfuric acid treatment which can be done by any known manner.
The oil thus obtained by known method was put on a column of Gas liquid Chromatogram for analysis of its fatty acid contents.
When this oil was externally applied on patients suffering from muscular pain, gangrene wounds or arthritic, gave great relief. The following typical example is given to illustrate the invention.
EXAMPLE I
The 100 g seeds of Momordica charantia L.. (bitter gourd) collected from the field were splitted, crushed and powdered. The seed powder was treated with 0.1 of 25 ml of sulfuric acid. The mixture after 5-10 min. was filtered and the residue was extracted with hexane and either in succession. The oil thus obtained measured to 20-25%.
The oil was purified further for chemical analysis using Gas Liquid chromatogram which showed the presence of 7 fatty acids as:
1. Capric acid (0.9%)
2. Laurie acid (0.8%)
3. Palmitic acid (4.2%)
4. Stearic acid (60.90%)
5. Oleic acid (13.30%)
6. Archidic acid (3.20%)
7. Linoleic acid (9.80%)
8. Other undetected minor acids (6.90%)
The Stearic acid was maximum in amount followed by Oleic acid, linoleic acid and others.
When this oil was applied externally on about 100 patients suffering from muscular pain/ inflammation/ arthritis/ old wounds as gangrene, showed antiinflammatory, pain relieving and vasculodialatory properties and felt relieved.
The invention as described above and particularly in Example I as nearly an illustrated in nature and in no way it should be construed to limit the scope of the invention. Further modifications are possible without departing from the soul of the invention.

I CLAIM
1. An anti-inflammatory, ant arthritic and a vasculodilator herbal oil from seeds of
Momordica charantia L., (bitter gourd) obtained by the process which comprises
the treatment of seeds of Momordica charantia L., (bitter gourd) with dilute
sulfuric acid followed by the extraction with hexane and either in succession.
2. An oil as claimed in claim I wherein the seeds are preferably crushed, powdered
before treatment with sulfuric acid.
3. An oil, as claimed in claim I, is anti-inflammatory, antiarthritic, vasculodilator and a wound healer substantially as herein - before described with reference to any of the foregoing example.
4. JP 3092116 (9/04/1990) Method for producing bitter taste removed piece or powder of monostich charities.
5. IN S1887 (16/08/1995) A process for the isolation of blood sugar dowering active principle form the fricative of memories charantia .

Documents:

2191-del-1996-abstract.pdf

2191-del-1996-claims.pdf

2191-del-1996-correspondence-others.pdf

2191-del-1996-correspondence-po.pdf

2191-del-1996-description (complete).pdf

2191-del-1996-form-1.pdf

2191-del-1996-form-19.pdf

2191-del-1996-form-2.pdf

2191-del-1996-pct-search report.pdf

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Patent Number

234274

Indian Patent Application Number

2191/DEL/1996

PG Journal Number

22/2009

Publication Date

29-May-2009

Grant Date

15-May-2009

Date of Filing

08-Oct-1996

Name of Patentee

DR. PUSHPA KHANNA

Applicant Address

E-14/7 VASANT VIHAR, NEW DELHI-110057

Inventors:

#	Inventor's Name	Inventor's Address
1	PUSHPA KHANNA	E-14/7 VASANT VIHAR, NEW DELHI-110057

PCT International Classification Number

A61K 037/26

PCT International Application Number

N/A

PCT International Filing date

PCT Conventions:

#	PCT Application Number	Date of Convention	Priority Country
1			NA