Title of Invention | METHODS FOR PRODUCING HYALURONIC ACID IN A RECOMBINANT HOST CELL |
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Abstract | A method producing a hyaluronIc add, comprislng: (I) cultivating a bacillus host. under wndilions suitable for productiOn of the hyaluronit add, wherein the 8BcIIJtJS host (211 Q)tnprileS nucleic add prtsing a synthelic on for produdng the hyaluronic add in Ute SIdl/u$ cell, wtrereJn the synttIetk: operon CQlnptises a promoter sequence operably acuve in the bacillus tell and operably linked to e hyaluron&n synttIase encoding sequence, a UDP-gl~ 6-dehydrogenase encoding sequence, and a UDP glucose pyrar(lase encoding sequence, and wherein the promoter sequence is foreign to ead} of the erklXIing seque of the synt21etIc operon, directs tanscrirtion of the encoding sequences, and is a "consensus" promoter having the sequence TTGACA f()( the ". 35" region and TATAAT for the "-10" region; and (b) recovering the hyaluronic add !rum the cultivation medium. |
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1389-chenp-2004 assignment 30-07-2009.pdf
1389-chenp-2004 claims granted.pdf
1389-chenp-2004 correspondence others 30-07-2009.pdf
1389-chenp-2004 correspondence others.pdf
1389-chenp-2004 correspondence po.pdf
1389-chenp-2004 description (complete) granted.pdf
1389-chenp-2004 form-16 30-07-2009.pdf
1389-chenp-2004 form-26 30-07-2009.pdf
1389-chenp-2004 power of attorney.pdf
Patent Number | 228623 | |||||||||||||||||||||
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Indian Patent Application Number | 1389/CHENP/2004 | |||||||||||||||||||||
PG Journal Number | 12/2009 | |||||||||||||||||||||
Publication Date | 20-Mar-2009 | |||||||||||||||||||||
Grant Date | 05-Feb-2009 | |||||||||||||||||||||
Date of Filing | 21-Jun-2004 | |||||||||||||||||||||
Name of Patentee | NOVOZYMES BIOPOLYMER A/S | |||||||||||||||||||||
Applicant Address | KROGSHOJVEJ 36, DK-2880 BAGSVAERD, | |||||||||||||||||||||
Inventors:
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PCT International Classification Number | C12N | |||||||||||||||||||||
PCT International Application Number | PCT/US02/41067 | |||||||||||||||||||||
PCT International Filing date | 2002-12-20 | |||||||||||||||||||||
PCT Conventions:
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