Title of Invention

METHODS FOR PRODUCING HYALURONIC ACID IN A RECOMBINANT HOST CELL

Abstract A method producing a hyaluronIc add, comprislng: (I) cultivating a bacillus host. under wndilions suitable for productiOn of the hyaluronit add, wherein the 8BcIIJtJS host (211 Q)tnprileS nucleic add prtsing a synthelic on for produdng the hyaluronic add in Ute SIdl/u$ cell, wtrereJn the synttIetk: operon CQlnptises a promoter sequence operably acuve in the bacillus tell and operably linked to e hyaluron&n synttIase encoding sequence, a UDP-gl~ 6-dehydrogenase encoding sequence, and a UDP glucose pyrar(lase encoding sequence, and wherein the promoter sequence is foreign to ead} of the erklXIing seque of the synt21etIc operon, directs tanscrirtion of the encoding sequences, and is a "consensus" promoter having the sequence TTGACA f()( the ". 35" region and TATAAT for the "-10" region; and (b) recovering the hyaluronic add !rum the cultivation medium.
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Documents:

1389-chenp-2004 abstract.pdf

1389-chenp-2004 assignment 30-07-2009.pdf

1389-chenp-2004 claims granted.pdf

1389-chenp-2004 correspondence others 30-07-2009.pdf

1389-chenp-2004 correspondence others.pdf

1389-chenp-2004 correspondence po.pdf

1389-chenp-2004 description (complete) granted.pdf

1389-chenp-2004 drawings.pdf

1389-chenp-2004 form 1.pdf

1389-chenp-2004 form 18.pdf

1389-chenp-2004 form 3.pdf

1389-chenp-2004 form 5.pdf

1389-chenp-2004 form-16 30-07-2009.pdf

1389-chenp-2004 form-26 30-07-2009.pdf

1389-chenp-2004 pct.pdf

1389-chenp-2004 petition.pdf

1389-chenp-2004 power of attorney.pdf


Patent Number 228623
Indian Patent Application Number 1389/CHENP/2004
PG Journal Number 12/2009
Publication Date 20-Mar-2009
Grant Date 05-Feb-2009
Date of Filing 21-Jun-2004
Name of Patentee NOVOZYMES BIOPOLYMER A/S
Applicant Address KROGSHOJVEJ 36, DK-2880 BAGSVAERD,
Inventors:
# Inventor's Name Inventor's Address
1 SLOMA, ALSN 849 DONOVAN COURT, DAVIS, CA 95616,
2 BEHR, REGINE 1017 DANIELLE DRIVE, ROSEVILLE, CA 95747,
3 WIDNER, WILLIAM 804 E. 9TH STREET, APT. 107, DAVIS, CA 95616,
4 TANG, MARIA 2043 CLIFFWOOD DRIVE, FAIRFIELD, CA 94033,
5 STERNBERG, DAVID 3205 BRETON AVENUE, DAVIS, CA 95616,
6 BROWN, STEPHEN 3708 MIWOK PLACE, DAVIS, CA 95616,
PCT International Classification Number C12N
PCT International Application Number PCT/US02/41067
PCT International Filing date 2002-12-20
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 60/342,644 2001-12-21 U.S.A.