Title of Invention	A PROCESS FOR THE PREPARATION OF AN AROMATIC POLYETHERKETONE
Abstract	The present invention relates to a process for the preparation of an aromatic polyetherketone which process comprises: a) self-condensing a compound of formula I in the presence of an alkyl or optionally substituted aryl sulphonic acid solvent and in the absence of phosphorous pentoxide; or b) condensing a compound of general formula II and a compound of general formula III in the presence of an alkyl or optionally substituted aryl sulphonic acid solvent and in the absence of phosphorous pentoxide; or c) a combination of a) and b).

Title of Invention

A PROCESS FOR THE PREPARATION OF AN AROMATIC POLYETHERKETONE

Abstract

The present invention relates to a process for the preparation of an aromatic polyetherketone which process comprises: a) self-condensing a compound of formula I in the presence of an alkyl or optionally substituted aryl sulphonic acid solvent and in the absence of phosphorous pentoxide; or b) condensing a compound of general formula II and a compound of general formula III in the presence of an alkyl or optionally substituted aryl sulphonic acid solvent and in the absence of phosphorous pentoxide; or c) a combination of a) and b).

Full Text	This invention relates to a process for the preparation of an aromatic polyetherketone and particularly, although not exclusively, relates to a process for the preparation of aromatic polyetherketones. Electrophilic routes for the preparation of aromatic polyetherketones are well known and these include direct polycondensation of aromatic discarboxylic acids with aromatic diethers or self-condensation of phenoxybenzoic acids. For example, Ueda and Sato in Macromolecules 1987, 20, 2675 and Ueda and Oda in Polymer Journal vol. 21, No. 9, 673 (1989) describe such condensation reactions using phosphorous pentoxide/methanesulphonic acid as a condensing agent and solvent. Although polyetherketones can be prepared as described, it has been found that, due to the use of phosphorous pentoxide, the polymer is relatively difficult to recover. Furthermore, phosphorous pentoxide is an unpleasant reagent. It is an object of the present invention to address the above-described problems. The invention is based on the discovery that aromatic polyetherketones can be prepared using certain solvents in the absence of phosphorous pentoxide. According to the invention, there is provided a process for the preparation of an aromatic polyetherketone which process comprises: a) self-condensing a compound of formula wherein n represents 0 or 1 in the presence of an alkyl or optionally substituted aryl sulphonic acid solvent and in the absence of phosphorous pentoxide; or b) condensing a compound of general formula III wherein p and q independently represent 0 or 1, in the presence of an alkyl or optionally substituted aryl sulphonic acid solvent and in the absence of phosphorous pentoxide; or c) a combination of a) and b). Except where otherwise stated throughout this specification, any alkyl moiety suitably has up to 8, especially up to 6, most preferably up to 4, carbon atoms and may be of straight chain or, where possible, of branched chain structure. Except where otherwise stated throughout this specification, optional substituents of an aryl, for example a phenyl group include halogen atoms especially fluorine, chlorine, bromine and iodine atoms, and nitro, cyano, alkoxy, hydroxy, amino, alkylamino, sulphinyl, alkylsulphinyl, sulphonyl, alkylsulphonyl, amido, alkylamido, alkoxycarbonyl, haloalkoxycarbonyl and haloalkyl groups. Preferred optional substituents are halogen atoms, especially fluorine and chlorine atoms. Said sulphonic acid solvent is suitably able to absorb water formed in the polycondensation. Other means for removing water and thereby driving the reaction towards polymer formation may be used in the process. For example, the process may be carried out at an elevated temperature. (Preferably, the process is carried out at a temperature of greater than 60°C, more preferably at greater than 80°C and, especially preferred, at greater than 100°C. ] In addition to an elevated temperature, an J azeotropic means for removing water may be utilised by adding a solvent, for example xylene or toluene or the like to the mixture and heating so that a mixture of water and solvent boil off. Another means for removing water may comprise directing an inert gas, for example nitrogen gas, into the reaction mixture in order to cause water formed in the reaction to be driven off. The process is preferably carried out in the absence of any phosphorous-containing reagent. This may ensure that no neutralisation step is required after the polycondensation reaction. The process is preferably carried out in the absence of any dehydrating agent other than the aforementioned sulphonic acid solvent. Said solvent is preferably adapted to stabilise the forming polymer, thereby to maintain it in solution so that relatively high molecular weight polymers can be obtained. Said solvent may be an alkyl or unsubstituted aryl sulphonic acid. Where said solvent is an alkyl sulphonic acid, it is preferably a Ci-4 alkyl, more preferably a C1-2 alkyl sulphonic acid. An especially preferred solvent is methanesulphonic acid. Where said solvent is an aryl sulphonic acid, it is preferably optionally substituted, more preferably unsubstituted, benzene sulphonic acid. Suitably, an aromatic polyetherketone of formula is prepared in processes a, b or c. In process a), n preferably represents l. In processes b) or c), p and q preferably represent 1. Preferably, said aromatic polyetherketone is prepared by process a) above. Said aromatic polyetherketone formed in the process is suitably a tough crystalline thermoplastic polymer. It may have an inherent viscosity (IV) of at least 0.7 dl/g, preferably at least 0.8 dl/g and, more preferably, at least 0. 9 dl/g. In the context of this specification IV is measured at 25°C on a solultion of polymer in concentrated sulphuric acid of density 1.84 g.cm"3, said solution containing O.lg of polymer per 100 cm3 of solution. In the process, said compound of general formula I and said solvent or said compounds of general formulae II and III and said solvent are suitably mixed together under a nitrogen atmosphere at a temperature of greater than 60°C for at least 10 hours and preferably at least 20 hours to form a viscous solution. A minor amount of an end-capping agent, for example an aromatic ether compound such as 1,4-diphenoxybenzene, is suitably included in the mixture. -^ The ratio of the number of moles of compound of general formula I or the sum of the number of moles of compounds of general formulae II and III to that of the end-capping agent may be in the range 100:1 to 20:1, preferably in the range 75:1 to 35:1. The viscous solution formed is suitably added in small amounts to water, suitably with stirring. The polymer precipitates and can then be recovered, purified and dried. Compounds of general formula I, II and III and said solvents are commercially available and/or can be prepared using standard techniques. The invention extends to an aromatic polyetherketone prepared according to the process described herein. The invention will now be described by way of example. Example 1 A 3-necked round-bottomed flask, fitted with a condenser arm, a stirrer, a nitrogen sparge and a thermometer, was charged with 4-(4-phenoxyphenoxy)benzoic acid (9.2 g, 30 mmole), 1,4-diphenyoxybenzene (0.157 g, 0.6 mmole) and methanesulphonic acid (100ml) and stirred under a nitrogen atmosphere at 120°C for 24 hours. The resulting viscous solution was added dropwise to vigorously stirred water (1 litre). The precipitated polymer was recovered by filtration, stirred in boiling water for 1 hour, filtered, washed with acetone and dried under vacuum at 12 0°C for 24 hours. The inherent viscosity (IV) of the polymer was 0.93 dl/g measured on a 0.1% solution of the polymer in 95% sulphuric acid at 25°C. Example 2 The process of Example 1 was repeated using benzenesulphonic acid instead of methanesulphonic acid. The resultant polymer had an IV of 0.86 dl/g. The reader's attention is directed to all papers and documents which are filed concurrently with or previous to this specification in connection with this application and which are open to public inspection with this specification, and the contents of all such papers and documents are incorporated herein by reference. All of the features disclosed in this specification (including any accompanying claims, abstract and drawings) , and/or all of the steps of any method or process so disclosed, may be combined in any combination, except combinations where at least some of such features and/or steps are mutually exclusive. Each feature disclosed in this specification (including any accompanying claims, abstract and drawings), may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise. Thus, unless expressly stated otherwise, each feature disclosed is one example only of a generic series of equivalent or similar features. The invention is not restricted to the details of the foregoing embodiment(s). The invention extend to any novel one, or any novel combination, of the features disclosed in this specification (including any accompanying claims, abstract and drawings) , or to any novel one, or any novel combination, of the steps of any method or process so disclosed. WE CLAIM: 1. A process for the preparation of an aromatic polyetherketone which process comprises: a) self-condensing a compound of formula wherein n represents 0 or 1 in the presence of an alkyl or optionally substituted aryl sulphonic acid solvent and in the absence of phosphorous pentoxide; or b) condensing a compound of general formula wherein p and q independently represent 0 or 1? in the presence of an alkyl or optionally substituted aryl sulphonic acid solvent and in the absence of phosphorous pentoxide; or c) a combination of a) and b). 2. The process as claimed in claim 1 wherein said sulphonic acid solvent is able to absorb water formed in the polycondensation. 3. The process as claimed in any one of the preceding claims wherein an azeotropic means for removing water is utilized by adding a solvent and heating so that a mixture of water and solvent boil off. 4. The process as claimed in any one of the preceding claims wherein an inert gas is directed into the reaction mixture in order to cause water formed in the reaction to be driven off. 5. The process as claimed in any one of the preceding claims wherein the process is carried out in the absence of any phosphorous - containing reagents. 6. The process as claimed in any one of the preceding claims wherein the process is carried out in the absence of any dehydrating agent other than the said sulphonic acid solvent. 7. The process as claimed in any one of the preceding claims wherein said solvent is adapted to stabilize the forming polymer, thereby to maintain it in solution so that high molecular weight polymers can be obtained. 8. The process as claimed in any one of the preceding claims wherein said solvent is an alkyl or unsubstituted aryl sulphonic acid. 9. The process as claimed in any one of the preceding claims wherein said solvent is a CM alkyl sulphonic acid. 10. The process as claimed in any one of the preceding claims wherein said solvent is methanesulphonic acid. 11. The process as claimed in any one of claims 1 to 8 wherein said solvent is benzene sulphonic acid. 12. The process as claimed in any one of the preceding claims wherein n represents 1. 13. The process as claimed in any one of the preceding claims wherein p and q represent 1. 14. The process as claimed in any one of claims 1 to 12 wherein said aromatic polyetherketone is prepared by process a). 15. The process as claimed in any one of the preceding claims wherein said aromatic polyetherketone formed in the process is a crystalline thermoplastic polymer. 16. The process as claimed in any one of the preceding claims wherein said aromatic polyetherketone has an inherent viscosity of at least 0.7 dl/g. 17. The process as claimed in any one of the preceding claims wherein an end-capping agent is included in the mixture and the ratio of the number of moles of compound of general formula I or the sum of the number of moles of compounds of general formulae II and III to that of the end capping agent is in the range 100:1 to 20:1. 18. The process as claimed in claim 17 wherein the end capping agent is an aromatic ether compound. 19. The process as claimed in claim 17 or claim 18 wherein the end-capping agent is 1,4-diphenoxybenzene. 20. The process as claimed in any one of the preceding claims wherein said polyetherketone polymer is precipitated from solution and recovered, purified and dried.

Full Text

This invention relates to a process for the preparation of an aromatic polyetherketone and particularly, although not exclusively, relates to a process for the preparation of aromatic polyetherketones.
Electrophilic routes for the preparation of aromatic polyetherketones are well known and these include direct polycondensation of aromatic discarboxylic acids with aromatic diethers or self-condensation of phenoxybenzoic acids. For example, Ueda and Sato in Macromolecules 1987, 20, 2675 and Ueda and Oda in Polymer Journal vol. 21, No. 9, 673 (1989) describe such condensation reactions using phosphorous pentoxide/methanesulphonic acid as a condensing agent and solvent. Although polyetherketones can be prepared as described, it has been found that, due to the use of phosphorous pentoxide, the polymer is relatively difficult to recover. Furthermore, phosphorous pentoxide is an unpleasant reagent.
It is an object of the present invention to address the above-described problems.
The invention is based on the discovery that aromatic polyetherketones can be prepared using certain solvents in the absence of phosphorous pentoxide.
According to the invention, there is provided a process for the preparation of an aromatic polyetherketone which process comprises:

a) self-condensing a compound of formula

wherein n represents 0 or 1 in the presence of an alkyl or optionally substituted aryl sulphonic acid solvent and in the absence of phosphorous pentoxide; or
b) condensing a compound of general formula

III
wherein p and q independently represent 0 or 1, in the presence of an alkyl or optionally substituted aryl sulphonic acid solvent and in the absence of phosphorous pentoxide; or

c) a combination of a) and b).
Except where otherwise stated throughout this specification, any alkyl moiety suitably has up to 8, especially up to 6, most preferably up to 4, carbon atoms and may be of straight chain or, where possible, of branched chain structure.
Except where otherwise stated throughout this specification, optional substituents of an aryl, for example a phenyl group include halogen atoms especially fluorine, chlorine, bromine and iodine atoms, and nitro, cyano, alkoxy, hydroxy, amino, alkylamino, sulphinyl, alkylsulphinyl, sulphonyl, alkylsulphonyl, amido, alkylamido, alkoxycarbonyl, haloalkoxycarbonyl and haloalkyl groups. Preferred optional substituents are halogen atoms, especially fluorine and chlorine atoms.
Said sulphonic acid solvent is suitably able to absorb
water formed in the polycondensation. Other means for
removing water and thereby driving the reaction towards
polymer formation may be used in the process. For
example, the process may be carried out at an elevated
temperature. (Preferably, the process is carried out at a
temperature of greater than 60°C, more preferably at
greater than 80°C and, especially preferred, at greater
than 100°C. ] In addition to an elevated temperature, an
J azeotropic means for removing water may be utilised by
adding a solvent, for example xylene or toluene or the
like to the mixture and heating so that a mixture of water
and solvent boil off.

Another means for removing water may comprise directing an inert gas, for example nitrogen gas, into the reaction mixture in order to cause water formed in the reaction to be driven off.
The process is preferably carried out in the absence of any phosphorous-containing reagent. This may ensure that no neutralisation step is required after the polycondensation reaction.
The process is preferably carried out in the absence of any dehydrating agent other than the aforementioned sulphonic acid solvent.
Said solvent is preferably adapted to stabilise the forming polymer, thereby to maintain it in solution so that relatively high molecular weight polymers can be obtained.
Said solvent may be an alkyl or unsubstituted aryl sulphonic acid.
Where said solvent is an alkyl sulphonic acid, it is preferably a Ci-4 alkyl, more preferably a C1-2 alkyl sulphonic acid. An especially preferred solvent is methanesulphonic acid.
Where said solvent is an aryl sulphonic acid, it is preferably optionally substituted, more preferably unsubstituted, benzene sulphonic acid.
Suitably, an aromatic polyetherketone of formula

is prepared in processes a, b or c.
In process a), n preferably represents l.
In processes b) or c), p and q preferably represent 1.
Preferably, said aromatic polyetherketone is prepared by process a) above.
Said aromatic polyetherketone formed in the process is suitably a tough crystalline thermoplastic polymer. It may have an inherent viscosity (IV) of at least 0.7 dl/g, preferably at least 0.8 dl/g and, more preferably, at least 0. 9 dl/g.
In the context of this specification IV is measured at 25°C on a solultion of polymer in concentrated sulphuric acid of density 1.84 g.cm"3, said solution containing O.lg of polymer per 100 cm3 of solution.

In the process, said compound of general formula I and said solvent or said compounds of general formulae II and III and said solvent are suitably mixed together under a nitrogen atmosphere at a temperature of greater than 60°C for at least 10 hours and preferably at least 20 hours to form a viscous solution. A minor amount of an end-capping agent, for example an aromatic ether compound such as 1,4-diphenoxybenzene, is suitably included in the mixture. -^
The ratio of the number of moles of compound of general formula I or the sum of the number of moles of compounds of general formulae II and III to that of the end-capping agent may be in the range 100:1 to 20:1, preferably in the range 75:1 to 35:1.
The viscous solution formed is suitably added in small amounts to water, suitably with stirring. The polymer precipitates and can then be recovered, purified and dried.
Compounds of general formula I, II and III and said solvents are commercially available and/or can be prepared using standard techniques.
The invention extends to an aromatic polyetherketone prepared according to the process described herein.
The invention will now be described by way of example.
Example 1
A 3-necked round-bottomed flask, fitted with a condenser arm, a stirrer, a nitrogen sparge and a thermometer, was

charged with 4-(4-phenoxyphenoxy)benzoic acid (9.2 g, 30 mmole), 1,4-diphenyoxybenzene (0.157 g, 0.6 mmole) and methanesulphonic acid (100ml) and stirred under a nitrogen atmosphere at 120°C for 24 hours. The resulting viscous solution was added dropwise to vigorously stirred water (1 litre). The precipitated polymer was recovered by filtration, stirred in boiling water for 1 hour, filtered, washed with acetone and dried under vacuum at 12 0°C for 24 hours. The inherent viscosity (IV) of the polymer was 0.93 dl/g measured on a 0.1% solution of the polymer in 95% sulphuric acid at 25°C.
Example 2
The process of Example 1 was repeated using benzenesulphonic acid instead of methanesulphonic acid. The resultant polymer had an IV of 0.86 dl/g.
The reader's attention is directed to all papers and documents which are filed concurrently with or previous to this specification in connection with this application and which are open to public inspection with this specification, and the contents of all such papers and documents are incorporated herein by reference.
All of the features disclosed in this specification (including any accompanying claims, abstract and drawings) , and/or all of the steps of any method or process so disclosed, may be combined in any combination, except combinations where at least some of such features and/or steps are mutually exclusive.

Each feature disclosed in this specification (including any accompanying claims, abstract and drawings), may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise. Thus, unless expressly stated otherwise, each feature disclosed is one example only of a generic series of equivalent or similar features.
The invention is not restricted to the details of the foregoing embodiment(s). The invention extend to any novel one, or any novel combination, of the features disclosed in this specification (including any accompanying claims, abstract and drawings) , or to any novel one, or any novel combination, of the steps of any method or process so disclosed.

WE CLAIM:
1. A process for the preparation of an aromatic polyetherketone which process
comprises:
a) self-condensing a compound of formula

wherein n represents 0 or 1 in the presence of an alkyl or optionally substituted aryl sulphonic acid solvent and in the absence of phosphorous pentoxide; or
b) condensing a compound of general formula
wherein p and q independently represent 0 or 1? in the presence of an alkyl or optionally substituted aryl sulphonic acid solvent and in the absence of phosphorous pentoxide; or
c) a combination of a) and b).
2. The process as claimed in claim 1 wherein said sulphonic acid solvent is able to
absorb water formed in the polycondensation.
3. The process as claimed in any one of the preceding claims wherein an azeotropic means for removing water is utilized by adding a solvent and heating so that a mixture of water and solvent boil off.
4. The process as claimed in any one of the preceding claims wherein an inert gas is directed into the reaction mixture in order to cause water formed in the reaction to be driven off.
5. The process as claimed in any one of the preceding claims wherein the process is carried out in the absence of any phosphorous - containing reagents.
6. The process as claimed in any one of the preceding claims wherein the process is carried out in the absence of any dehydrating agent other than the said sulphonic acid solvent.
7. The process as claimed in any one of the preceding claims wherein said solvent is adapted to stabilize the forming polymer, thereby to maintain it in solution so that high molecular weight polymers can be obtained.
8. The process as claimed in any one of the preceding claims wherein said solvent is an alkyl or unsubstituted aryl sulphonic acid.
9. The process as claimed in any one of the preceding claims wherein said solvent is a CM alkyl sulphonic acid.
10. The process as claimed in any one of the preceding claims wherein said solvent is
methanesulphonic acid.
11. The process as claimed in any one of claims 1 to 8 wherein said solvent is benzene sulphonic acid.
12. The process as claimed in any one of the preceding claims wherein n represents 1.
13. The process as claimed in any one of the preceding claims wherein p and q represent 1.
14. The process as claimed in any one of claims 1 to 12 wherein said aromatic polyetherketone is prepared by process a).
15. The process as claimed in any one of the preceding claims wherein said aromatic polyetherketone formed in the process is a crystalline thermoplastic polymer.
16. The process as claimed in any one of the preceding claims wherein said aromatic polyetherketone has an inherent viscosity of at least 0.7 dl/g.
17. The process as claimed in any one of the preceding claims wherein an end-capping agent is included in the mixture and the ratio of the number of moles of compound of general formula I or the sum of the number of moles of compounds of general formulae II and III to that of the end capping agent is in the range 100:1 to 20:1.
18. The process as claimed in claim 17 wherein the end capping agent is an aromatic ether compound.
19. The process as claimed in claim 17 or claim 18 wherein the end-capping agent is
1,4-diphenoxybenzene.
20. The process as claimed in any one of the preceding claims wherein said
polyetherketone polymer is precipitated from solution and recovered, purified and
dried.

Documents:

0128-mas-2001 abstract duplicate.pdf

0128-mas-2001 claims duplicate.pdf

0128-mas-2001 description (complete) duplicate.pdf

128-mas-2001-abstract.pdf

128-mas-2001-claims.pdf

128-mas-2001-correspondence others.pdf

128-mas-2001-correspondence po.pdf

128-mas-2001-descrption complete.pdf

128-mas-2001-form 1.pdf

128-mas-2001-form 18.pdf

128-mas-2001-form 26.pdf

128-mas-2001-form 3.pdf

128-mas-2001-form 5.pdf

128-mas-2001-pct.pdf

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Patent Number

222506

Indian Patent Application Number

128/MAS/2001

PG Journal Number

47/2008

Publication Date

21-Nov-2008

Grant Date

14-Aug-2008

Date of Filing

12-Feb-2001

Name of Patentee

VICTREX MANUFACTURING LIMITED

Applicant Address

VICTREX TECHNOLOGY CENTRE, HILLHOUSE INTERNATIONAL, PO BOX 4 THORNTON CLEVELEYS, LANCASHIRE FY5 4QD,

Inventors:

#	Inventor's Name	Inventor's Address
1	DAVID JOHN KEMMISH	10 WHITTLE GREEN, WOODPLUMPTON, PRESTON, LANCASHIRE, PR4 0WG,
2	BRIAN WILSON	1 WHITE LEA, CABUS, GARSTANG, LANCASHIRE, PR3 1JG,

PCT International Classification Number

C08G65/40

PCT International Application Number

N/A

PCT International Filing date

PCT Conventions:

#	PCT Application Number	Date of Convention	Priority Country
1	0003011.4	2000-02-11	U.K.