Title of Invention | PYRIDAZINYL PHENYL HYDRAZONE COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME. |
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Abstract | Therapeutically active compounds of formula (I) in which R1 to R4 means hydrogen, alkyl, alkenyl, aryl, arylalkyl, carboxyalkyl, hydroxyalkyl or halogenalkyl, or R2 and R3 form a ring of 5-7 carbon atoms, R5 to R9 means hydrogen, alkyl, alkenyl, aryl, arylalkyl, acyl, hydroxy, alkoxy, alkoxycarbonyl, amino, acylamino, alkylamino, aryloxy, halogen, cyano, nitro, carboxy, alkylsulfonyl, sulfonamido or trifluoromethyl, wherein each aryl residue defined above by itself or as a part of another group may be substituted, and pharmaceutically acceptable salts and esters thereof. The compounds increase the calcium sensitivity of contractile proteins of the cardiac muscle and are thus useful in the treatment of congestive heart failure. |
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IN-PCT-2002-1121-KOL-CORRESPONDENCE.pdf
IN-PCT-2002-1121-KOL-FORM 27.pdf
in-pct-2002-1121-kol-granted-abstract.pdf
in-pct-2002-1121-kol-granted-assignment.pdf
in-pct-2002-1121-kol-granted-claims.pdf
in-pct-2002-1121-kol-granted-correspondence.pdf
in-pct-2002-1121-kol-granted-description (complete).pdf
in-pct-2002-1121-kol-granted-examination report.pdf
in-pct-2002-1121-kol-granted-form 1.pdf
in-pct-2002-1121-kol-granted-form 18.pdf
in-pct-2002-1121-kol-granted-form 3.pdf
in-pct-2002-1121-kol-granted-form 5.pdf
in-pct-2002-1121-kol-granted-gpa.pdf
in-pct-2002-1121-kol-granted-letter patent.pdf
in-pct-2002-1121-kol-granted-reply to examination report.pdf
in-pct-2002-1121-kol-granted-specification.pdf
in-pct-2002-1121-kol-granted-translated copy of priority document.pdf
Patent Number | 222462 | |||||||||||||||||||||||||||||||||
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Indian Patent Application Number | IN/PCT/2002/1121/KOL | |||||||||||||||||||||||||||||||||
PG Journal Number | 33/2008 | |||||||||||||||||||||||||||||||||
Publication Date | 15-Aug-2008 | |||||||||||||||||||||||||||||||||
Grant Date | 13-Aug-2008 | |||||||||||||||||||||||||||||||||
Date of Filing | 02-Sep-2002 | |||||||||||||||||||||||||||||||||
Name of Patentee | ORION CORPORATION | |||||||||||||||||||||||||||||||||
Applicant Address | ORIONINTIE 1, FIN-02200 ESPOO, | |||||||||||||||||||||||||||||||||
Inventors:
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PCT International Classification Number | C07D 237/04 | |||||||||||||||||||||||||||||||||
PCT International Application Number | PCT/FI0100241 | |||||||||||||||||||||||||||||||||
PCT International Filing date | 2001-03-12 | |||||||||||||||||||||||||||||||||
PCT Conventions:
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