| Title of Invention | COMPOSITION AND METHODS FOR THE PREPARATION OF HUMAN GROWTH HORMONE GLYCOSYLATION MUTANTS |
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| Abstract | The present invention relates to mutants of human growth hormone, which contain newly introduced N-linked or O-linked glycosylation site(s), such that these recombinantly produced polypeptides have glycosylation patterns distinctly different from that of the naturally occurring human growth hormone. The polynucleotide coding sequences for the mutants, expression cassettes comprising the coding sequences, cells expressing the mutants, and methods for producing the mutants are also disclosed. Further disclosed are pharmaceutical compositions comprising the mutants and method for using the mutants. |
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02351-kolnp-2005-description complete.pdf
02351-kolnp-2005-international publication.pdf
| Patent Number | 219939 | ||||||||||||||||||||
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| Indian Patent Application Number | 02351/KOLNP/2005 | ||||||||||||||||||||
| PG Journal Number | 20/2008 | ||||||||||||||||||||
| Publication Date | 16-May-2008 | ||||||||||||||||||||
| Grant Date | 14-May-2008 | ||||||||||||||||||||
| Date of Filing | 23-Nov-2005 | ||||||||||||||||||||
| Name of Patentee | NEOSE TECHNOLOGIES, INC | ||||||||||||||||||||
| Applicant Address | 102 WITMER ROAD, HORSHAM PA 19044, U.S.A. | ||||||||||||||||||||
Inventors:
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| PCT International Classification Number | A61K | ||||||||||||||||||||
| PCT International Application Number | PCT/US2004/014254 | ||||||||||||||||||||
| PCT International Filing date | 2004-05-07 | ||||||||||||||||||||
PCT Conventions:
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