| Title of Invention | S-NITROSOTHIOLS AS AGENTS FOR THE TREATMENT OF CIRCULATORY DYSFUNCTIONS. |
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| Abstract | The invention relates to novel S-nitrosothiols derived from penicillamine or glutathione of general formula (I), wherein A and B are phenyl groups or together represent a -CH2-Q-CH2- radical forming a six-membered ring in which Q represents an oxygen or sulfur atom or an N-R 3 radical , wherein R3 is hydrogen or an C1-C4 alkyl group; R1 is an acyl radical which may be a C1 -C5 aliphatic acyl radical or a glutamic acid radical bonded by its non-amino acid carboxyl ; R2 is a hydroxyl group or a glycine radical bonded by peptidic linkage in such a way that R2 is an hydroxyl group when R1 is an aliphatic acyl radical and R2 is a glycine radical when R1 is a glutamic acid radical . Said novel compounds exhibit vasodilating and blood platelet aggregation inhibiting activity and are useful in the treatment of circulatory system dysfunctions, especially cardiovascular dysfunctions . |
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in-pct-2001-00742-kol-granted-abstract.pdf
in-pct-2001-00742-kol-granted-assignment.pdf
in-pct-2001-00742-kol-granted-claims.pdf
in-pct-2001-00742-kol-granted-correspondence.pdf
in-pct-2001-00742-kol-granted-description (complete).pdf
in-pct-2001-00742-kol-granted-form 1.pdf
in-pct-2001-00742-kol-granted-form 18.pdf
in-pct-2001-00742-kol-granted-form 3.pdf
in-pct-2001-00742-kol-granted-form 5.pdf
in-pct-2001-00742-kol-granted-gpa.pdf
in-pct-2001-00742-kol-granted-letter patent.pdf
in-pct-2001-00742-kol-granted-reply to examination report.pdf
in-pct-2001-00742-kol-granted-specification.pdf
in-pct-2001-00742-kol-granted-translated copy of priority document.pdf
IN-PCT-2001-742-kol-CORRESPONDENCE.pdf
IN-PCT-2001-742-kol-FORM 27.pdf
| Patent Number | 218716 | ||||||||||||||||||||||||||||||||||||
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| Indian Patent Application Number | IN/PCT/2001/742/KOL | ||||||||||||||||||||||||||||||||||||
| PG Journal Number | 15/2008 | ||||||||||||||||||||||||||||||||||||
| Publication Date | 11-Apr-2008 | ||||||||||||||||||||||||||||||||||||
| Grant Date | 09-Apr-2008 | ||||||||||||||||||||||||||||||||||||
| Date of Filing | 16-Jul-2001 | ||||||||||||||||||||||||||||||||||||
| Name of Patentee | LACER S.A. | ||||||||||||||||||||||||||||||||||||
| Applicant Address | CALLE CERDENA, 350, E-08025, BARCELONA, | ||||||||||||||||||||||||||||||||||||
Inventors:
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| PCT International Classification Number | C07D 309/08 | ||||||||||||||||||||||||||||||||||||
| PCT International Application Number | PCT/ES00/00019 | ||||||||||||||||||||||||||||||||||||
| PCT International Filing date | 2000-01-19 | ||||||||||||||||||||||||||||||||||||
PCT Conventions:
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