Title of Invention

"ESTER SYNTHESIS".

Abstract

1. A process for the production of lower aliphatic esters said process comprising reacting a lower olefin selected from ethylene, propylene or mixtures thereof with a saturated lower aliphatic mono-carboxylic acid selected from Cl to C4 carboxylic acid in the vapour phase in the presence of a heteropolyacid catalyst of the kind such as herein described supported on a siliceous support which is in the form of extrudates or pellets wherein an amount of water is present in the reaction mixture in the range from 1-10 mole % based on the total weight of the olefm, aliphatic mono-carboxylic acid and water, and water is added to the reaction mixture during the reaction; and wherein the mole ratio of the olefin to the lower carboxylic acid in the reaction mixture is in the range from 1:1 to 15:1, the reaction mixture suitably having a molar excess of the olefin reactant with respect to the aliphatic mono-carboxylic acid reactant, and the reaction being carried out at a temperature in the range from 150-200oC and at a reaction pressure of at least 400 KPa, and the reaction mixture being optionally dosed with a di-ether suitably in the range from 1 to 6 mole% based on the total reaction mixture comprising the olefin, the aliphatic carboxylic acid, water and di-ether.

Full Text

The present invention relates to a process for the production of lower aliphatic esters and generally to a process for the synthesis of esters by reacting an olefin with a lower carboxylic acid in the presence of an acidic catalyst. It is well known that olefins can be reacted with lower aliphatic carboxylic acids to form the corresponding esters. One such method is described in GB-A-1259390 in which an ethylenically unsaturated compound is contacted with a liquid medium comprising a carboxylic acid and a free heteropolyacid of molybdenum or tungsten. This process is a homogeneous process in which the heteropolyacid catalyst is unsupported. A further process for producing esters is described in JP-A-05294894 in which a lower fatty acid is esterified with a lower olefm to form a lower fatty acid ester. In this document, the esterification reaction is carried out in the gaseous phase in the presence of a catalyst consisting of at least one heteropolyacid salt of a metal eg Li, Cu, Mg or K, being supported on a carrier. The heteropolyacid used is phosphotungstic acid and the carrier described is silica. It has now been found that the process efficiency can be improved significantly by co-feeding water to the reaction mixture. Accordingly, there is provided a process for the production of lower aliphatic esters said process comprising reacting a lower olefin selected from ethylene, propylene or mixtures thereof with a saturated lower aliphatic mono-carboxylic acid selected from Cl to C4 carboxylic acid in the vapour phase in the presence of a heteropolyacid catalyst of the kind such as herein described supported on a siliceous support which is in the form of extrudates or pellets wherein an amount of water is present in the reaction mixture in the range from 1-10 mole % based on the total weight of the olefin, aliphatic mono-carboxylic acid and water, and water is added to the reaction mixture during the reaction; and wherein the mole ratio of the olefin to the lower carboxylic acid in the reaction mixture is in the range from 1:1 to 15:1, the reaction mixture suitably having a molar excess of the olefin reactant with respect to the aliphatic mono-carboxylic acid reactant, and the reaction being carried out at a temperature in the range from 150-200°C and at a reaction pressure of at least 400 KPa, and the reaction mixture being optionally dosed with a di-ether suitably in the range from 1 to 6 mole% based on the total reaction mixture comprising the olefin, the aliphatic carboxylic acid, water and di-ether. Accordingly, the present invention is a process for the production of lower aliphatic esters said process comprising reacting a lower olefin with a saturated lower aliphatic mono-carboxylic acid in the vapour phase in the presence of a heteropolyacid catalyst characterised in that an amount of water in the range from 1-10 mole % based on the total of the olefin, aliphatic mono-carboxylic acid and water is added to the reaction mixture during the reaction. A feature of the invention is the addition of water as a component of the reaction mixture. Surprisingly, it has been found that the presence of water in the reaction mixture in an amount of 1-10 mole %, preferably from 1 to 7 mole %, eg 1 to 5 mole %, based on the total feed enhances the stability of the catalyst and thereby enhances the efficiency of the process. Furthermore, the presence of water also reduces the selectivity of the process to undesired by-products such as eg oligomers and other unknowns, excluding diethyl ether and ethanol. It has further been found that dosing the reaction mixture with amounts of di-ether such as eg diethyl ether, as a co-feed also reduces the formation of undesirable by-products. The amount of di-ether co-fed is suitably in the range from 1 to 6 mole %, preferably in the range from 1 to 3 mole % based on the total reaction mixture comprising the olefin, the aliphatic carboxylic acid, water and diethyl ether. The di-ether co-fed may correspond to the by product di-ether from the reaction generated from the reactant olefin. Where a mixture of olefins is used, eg a mixture of ethylene and propylene, the di-ether may in turn be an unsymmetrical di-ether. The di-ether co-feed may thus be the by-product of the reaction which by-product is recycled to the reaction mixture. The term "heteropolyacids" as used herein and throughout the specification is meant to include the free acids. The heteropolyacids used to prepare the esterification catalysts of the present invention therefore include inter alia the free acids and coordination type salts thereof in which the anion is a complex, high molecular weight entity. Typically, the anion is comprises 2-18 oxygen-linked polyvalent metal atoms, which are called peripheral atoms. These peripheral atoms surround one or more central atoms in a symmetrical manner. The peripheral atoms are usually one or more of molybdenum, tungsten, vanadium, niobium, tantalum and other metals. The central atoms are usually silicon or phosphorus but can comprise any one of a large variety of atoms from Groups I-VIII in the Periodic Table of elements. These include, for instance, cupric ions; divalent beryllium, zinc, cobalt or nickel ions; trivalent boron, aluminium, gallium, iron, cerium, arsenic, antimony, phosphorus, bismuth, chromium or rhodium ions; tetravalent silicon, germanium, tin, titanium, zirconium, vanadium, sulphur, tellurium, manganese nickel, platinum, thorium, hafnium, cerium ions and other rare earth ions; pentavalent phosphorus, arsenic, vanadium, antimony ions; hexavalent tellurium ions; and heptavalent iodine ions. Such heteropolyacids are also known as "polyoxoanions", "polyoxometallates" or "metal oxide clusters". The structures of some of the well known anions are named after the original researchers in this field and are known eg as Keggin, Wells-Dawson and Anderson-Evans-Perloff structures. Heteropolyacids usually have a high molecular weight eg in the range from 700-8500 and include dimeric complexes. They have a relatively high solubility in polar solvents such as water or other oxygenated solvents, especially if they are free acids and in the case of several salts, and their solubility can be controlled by choosing the appropriate counter-ions. Specific examples of heteropolyacids that may be used as the catalysts in the present invention include: 12-tungstophosphoric acid - H3[PW12O40].xH20 12-molybdophosphoric acid - H3[PMo12O40].xH2O 12-tungstosilicic acid - H4[SiW12O40]xH2O 12-molybdosilicic acid - H4SiMo12O40].xH2O Potassium tungstophosphate - K6[P2W18O62].xH2O Sodium molybdophosphate - Na3[PMo12O40].xH2O Ammonium molybdodiphosphate - (NH4)6[P2Mo18O62].xH2O Sodium tungstonickelate - Na4[NiW6O24H6].xH2O Ammonium molybdodicobaltate - (NH4)[Co2Mo10O36].xH2O Cesium hydrogen tungstosilicate - Cs3H[SiWi2O40].xH2O Potassium molybdodivanado phosphate - K5[PMoV2O40].xH2O The heteropolyacid catalyst whether used as a free acid or as a salt thereof is suitably supported, preferably on a siliceous support. The siliceous support is suitably in the form of extrudates or pellets. The siliceous support used is most preferably derived from an amorphous, non-porous synthetic silica especially fumed silica, such as those produced by flame hydrolysis of SiCl4. Specific examples of such siliceous supports include Support 350 made by pelletisation of AEROSIL® 200 (both ex Degussa). This pelletisation procedure is suitably carried out by the process described in US Patent 5,086,031 (see especially the Examples) and is incorporated herein by reference. Such a process of pelletisation or extrusion does not involve any steam treatment steps and the porosity of the support is derived from the interstices formed during the pelletisation or extrusion step of the non-porous silica The silica support is suitably in the form of pellets or beads or are globular in shape having an average particle diameter of 2 to 10 mm, preferably 4 to 6 mm. The siliceous support suitably has a pore volume in the range from 0.3-1.2 ml/g, preferably from 0.6-1.0 ml/g. The support suitably has a crush strength of at least 2 Kg force, suitably at least 5 Kg force, preferably at least 6 Kg and more preferably at least 7 Kg. The crush strengths quoted are based on average of that determined for each set of 50 beads/globules on a CHATTILLON tester which measures the minimum force necessary to crush a particle between parallel plates. The bulk density of the support is suitably at least 380 g/1, preferably at least 440 g/1. The support suitably has an average pore radius (prior to use) of 10 to 500A preferably an average pore radius of 30 to l00A. In order to achieve optimum performance, the siliceous support is suitably free of extraneous metals or elements which might adversely affect the catalytic activity of the system. The siliceous support suitably has at least 99% w/w purity, ie the impurities are less than 1% w/w, preferably less than 0.60% w/w and more preferably less than 0.30% w/w. Other pelleted silica supports are the Grace 57 and 1371 grades of silica. In paticular, Grace silica No. 1371 has an average bulk density of about 0.39 g/ml, an average pore volume of about 1.15 ml/g and an average particle size ranging from about 0.1-3.5 mm. These pellets can be used as such or after crushing to an average particle size in the range from 0.5-2 mm and sieving before being used as the support for the heteropolyacid catalyst. The impregnated support is suitably prepared by dissolving the heteropolyacid, which is preferably a tungstosilicic acid, in eg distilled water, and then adding the support to the aqueous solution so formed. The support is suitably left to soak in the acid solution for a duration of several hours, with periodic manual stirring, after which time it is suitably filtered using a Buchner funnel in order to remove any excess acid. The wet catalyst thus formed is then suitably placed in an oven at elevated temperature for several hours to dry, after which time it is allowed to cool to ambient temperature in a desiccator. The weight of the catalyst on drying, the weight of the support used and the weight of the acid on support was obtained by deducting the latter from the former from which the catalyst loading in g/litre was determined. Alternatively, the support may be impregnated with the catalyst using the incipient wetness technique with simultaneous drying on a rotary evaporator. This supported catalyst (measured by weight) can then be used in the esterification process. The amount of heteropolyacid deposited/impregnated on the support for use in the esterification reaction is suitably in the range from 10 to 60% by weight, preferably from 30 to 50% by weight based on the total weight of the heteropolyacid and the support. In the esterification reaction, the olefin reactant used is suitably ethylene, propylene or mixtures thereof. Where a mixture of olefins is used, the resultant product will inevitably a mixture of esters. The source of the olefin reactant used may be a refinery product or a chemical grade olefin which invariably contain some alkanes admixed therewith. The saturated, lower aliphatic mono-carboxylic acid reactant is suitably a C1-C4 carboxylic acid and is preferably acetic acid. The reaction mixture suitably comprises a molar excess of the olefin reactant with respect to the aliphatic mono-carboxylic acid reactant. Thus the mole ratio of olefin to the lower carboxylic acid in the reaction mixture is suitably in the range from 1:1 to 15 : 1, preferably from 10:1 to 14:1. The reaction is carried out in the vapour phase suitably above the dew point of the reactor contents comprising the reactant acid, any alcohol formed in situ, the product ester and water as stated above. The amount of water is in the range from 1-10 mole %, suitably from 1-7 mole %, preferably from 1-5 mole % based on the total amount of olefin, carboxylic acid and water. Dew point is the temperature at which condensation of a vapour of a given sample in air takes place. The dew point of any vaporous sample will depend upon its composition. The supported heteropolyacid catalyst is suitably used as a fixed bed which may be in the form of a packed column. The vapours of the reactant olefins and acids are passed over the catalyst suitably at a GHSV in the range from 100 to 5000 per hour, preferably from 300 to 2000 per hour. The esterification reaction is suitably carried out at a temperature in the range from 150-200°C using a reaction pressure which is at least 400 KPa, preferably from 500-3000 Kpa depending upon the relative mole ratios of olefin to acid reactant and the amount of water used. The water added to the reaction mixture is suitably present in the form of steam and is capable of generating a mixture of esters and alcohols in the process. The products of the reaction are recovered by eg fractional distillation. Where esters are produced, whether singly or as mixture of esters, these may be hydrolysed to the corresponding alcohols or mixture of alcohols in relatively high yields and purity. By using this latter technique the efficiency of the process to produce alcohols from olefins is significantly improved over the conventional process of producing alcohols by hydration of olefins. The present invention is further illustrated with reference to the following Examples and Comparative Tests. EXAMPLES: In all the Examples, the reaction conditions used and the results achieved are tabulated below. In these tables, the following abbreviations have been used: HOS Hours on stream Bed (T/M/B) Bed (top/middle/bottom) HAC Acetic Acid C2H4 Ethylene H2O Water EtAc Ethyl acetate EtOH Ethanol DEE Diethyl ether GHS V Gas hourly space velocity g/Lcat/h Gram per litre of catalyst per hour STP Standard temperature & pressure STY Space time yield Example 1; A. Catalyst Preparations: Catalyst 1: Silica granules (Grace 1371 grade, 530 m2/g, bulk density 0.39 g/ml, pore volume 1.15 ml/g, ca. 1-3 mm, 70 g, ex W R Grace) were soaked over 24 hours with intermittent stirring in a solution of silicotungstic acid [H4SiW12O40H2O] (65.53 g, ex Japan New Metals) dissolved in 250 mlo distilled water in order to impregnate the silica support with the silicophosphoric acid catalyst. After this duration, excess catalyst solution was decanted and filtered off. The resultant catalyst impregnated support was then dried in flowing nitrogen gas overnight at 120°C. The supported catalyst so formed was then left in a desiccator to cool and was finally reweighed. The resultant supported catalyst had a heteropolyacid catalyst loading of 92 g/litre. Catalyst2: Silica granules (Grace 57 grade, surface area 510 m2/g, bulk density 0.649 g/ml, pore volume 1.0267 ml/g, ca. 5-8 mm, 57.7 g, ex W R Grace) was soaked in a solution of 12-tungstosilicic acid [H4SiW12O40.26H2O] (ex Johnson Matthey, 69.4 g dissolved in 200 ml distilled water) for 24 hours with intermittent stirring in order to impregnate the support with the catalyst. Thereafter the excess solution of the silicotungstic acid catalyst was removed by decantation and filtration. The resultant catalyst impregnated support was then dried overnight under flowing nitrogen at 120°C. The dried supported catalyst so formed was cooled in a desiccator and had a heteropolyacid catalyst loading of 190g/litre. Catalyst 3: The above process of Catalyst 2 was repeated and was found to have a heteropolyacid catalyst loading of 192 g/litre. B. Catalyst Forming: All the catalysts produced above were broken down and sieved to obtain the desired pellet size for loading into the esterification reactor. C. Catalyst Testing: The reactor used was a three-zone Severn Sciences reactor constructed of Hastelloy C-276 capable of withstanding glacial acetic acid up to 300°C and 15000 Kpa (150 barg) pressure (length 650 mm, outer diameter 22 mm, internal diameter 16 mm). It had a thermowell running the entire reactor length (5 mm outer diameter) and 1.77 cm outer diameter Swagelock VCR joints at each end. Gas from cylinders of ethylene and nitrogen were taken off at 1000 Kpa (10 barg) and then compressed to 5000-12000 Kpa (50-120 barg), via Haskel boosters, before being regulated and fed to mass-flow controllers. The liquid feed systems had 2 dm3 reservoirs maintained under a nitrogen blanket of 10 KPa-80 KPa (0.1-0.8 barg). A cooling jacket was provided to condense products in the gas stream back to liquids prior to collection in a receiver. The majority of the liquid product was collected at room temperature. A pre-heating zone was located upstream of the catalyst bed. The pre-heating zone was separated from the catalyst bed by a plug of glass wool. Another plug of gas wool was used downstream of the catalyst bed to reduce dead volume and help maintain the catalyst bed in the centre section of the reactor. The reaction was started up by pressurising the reactor to 1000 KPa (10 barg) with nitrogen, establishing the desired flow rate (which is the same as that used later for the olefin feed) and then increasing the reactor temperature to the desired operating conditions (170°C or 180°C) over a one hour period. The liquid pump for the mixture of acetic acid/water mixture was switched on initially at the desired flow rate and the olefin admitted into the reactor on liquid breakthrough at the collection pots, usually after 2 to 3 hours. The flows were then adjusted to give the desired feed molar ratios and GHSVs. The reactor effluent was collected at regular intervals. Liquid product was drained off, weighed and then analysed by GC. The gas stream was sampled downstream of the liquid collection points and also analysed by GC. Total gas out during a test period was measured using a wet-gas meter. The above process/catalysts were used to esterify ethylene with acetic acid. The relative amounts of each of the Catalysts 1 to 3 used, their bed size and bed length in performing the esterfication reaction were as follows: (Table Removed)* Parameters of Catalyst 1 used for the Runs in Table 2 TABLE 1 Run Conditions: (1 Mole % Water added to feed) using Catalyst 1: (Table Removed)* - No added water used in this comparative test (not according to the invention) Product Analysis (Table 1 continued): (Table Removed)TABLE 2 Run Conditions: (1 Mole % Water added to feed) using Catalyst 1: (Table Removed)Product Analysis (Table 2 continued): (Table Removed)TABLE 3 Run Conditions: (1 Mole % Water added to feed) using Catalyst 2: (Table Removed)Product Analysis (Table 3 continued): (Table Removed)TABLE 4 Run Conditions: (5 Mole % Water added to feed) using Catalyst 2: (Table Removed)Product Analysis (Table 4 continued): (Table Removed)TABLE 5 Run Conditions: (5 Mole % Water added to feed) using Catalyst 3: (Table Removed)Product Analysis (Table 5 continued): (Table Removed)TABLE 6 Run Conditions: (5 Mole % Water added to feed) using Catalyst 3: (Table Removed)Product Analysis (Table 6 continued): (Table Removed)TABLE 7 Run Conditions: (5 Mole % Water added to feed) using Catalyst 3: (Table Removed)* co-fed additionally with 2 Mole % DEE. § - No diethyl ether used in this Run Product Analysis (Table 7 continued): (Table Removed)TABLE 8 Run Conditions: (5 Mole % Water + 2 Mole % DEE added to feed) using Catalyst 3: (Table Removed)Product Analysis (Table 8 continued): (Table Removed)TABLE 9 (Table Removed)Example 2: Catalyst Preparations: Catalyst 4. 12-Tungstophosphoric acid [H3PW12O4o.24H2O] (175 g) was dissolved in distilled water (250 ml). Lithium nitrate [LiNO3.2H2O] (0.652 g) was dissolved in distilled water (~ 5ml). The lithium nitrate solution was added dropwise to the tungstophosphoric acid solution to form Solution "A". Solution "A" was added to pelleted silica support ( Grace 1371 grade, 1-3 mm, 99.5 g, ex W R Grace) and left to soak over 24 hours with occasional stirring in order to impregnate the silica with the tungstophosphoric acid catalyst. After this duration, excess solution "A" was decanted and filtered off. The resultant catalyst impregnated support was then dried in flowing nitrogen gas initially at 150 °C for 3 hours and then raised to 200°C and maintained at that temperature for 5 hours. The supported catalyst so formed was then left in a desiccator to cool and was finally reweighed. The resultant supported catalyst had a final weight of 164.4 g, a net catalyst loading of 64.9 g and had the formula Li0.1H2.9PW12O40.24H2O/SiO2 corresponding to a loading of 255 g/1. Catalyst 4. Pelleted silica support (Grace 1371 grade, 1-3 mm, 70 g, ex W R Grace) was soaked in a solution (250 ml) of 12-tungstosilicic acid [H4SiW12O40.26H2O] (65.53 g in distilled water) for 24 hours with intermittent stirring in order to impregnate the support with the catalyst. Thereafter the excess solution of the tungstosilicic acid was removed by decantation and filtration. The resultant catalyst impregnated support was then dried overnight under flowing nitrogen at 120°C. The dried supported catalyst so formed was cooled in a desiccator and had a final weight of 86.2g, a net catalyst loading of 16.2 g and had the formula H4SiW12O40.26H2O/SiO2 corresponding to a loading of 92 g/1. The above catalysts were used to esterify ethylene with acetic acid. The relative amounts of each of these catalysts used, their bed size and bed length in performing the esterfication reaction were as follows: (Table Removed)TABLE 10 (Catalyst 4- 15.5g) Run Conditions: (Table Removed)Product Analysis (Table 10 continued): (Table Removed)TABLE 11 (Catalysts- 11.3g) Run Conditions: (Table Removed)Product Analysis (Table 11 continued): (Table Removed)TABLE 12 (Catalysts- 11.2g) Run Conditions: (Table Removed)Product Analysis (Table 12 continued): (Table Removed) (Catalyst 5 - 11.2 g) Run Conditions. (Table Removed)Product Analysis (Table 13 continued): (Table Removed)TABLE 14 (Catalysts - 11.4g) Run Conditions: (Table Removed)Product Analysis (Table 14 continued): (Table Removed) WE CLAIM: 1. A process for the production of lower aliphatic esters said process comprising reacting a lower olefin selected from ethylene, propylene or mixtures thereof with a saturated lower aliphatic mono-carboxylic acid selected from Cl to C4 carboxylic acid in the vapour phase in the presence of a heteropolyacid catalyst of the kind such as herein described supported on a siliceous support which is in the form of extrudates or pellets wherein an amount of water is present in the reaction mixture in the range from 1-10 mole % based on the total weight of the olefin, aliphatic mono-carboxylic acid and water, and water is added to the reaction mixture during the reaction; and wherein the mole ratio of the olefin to the lower carboxylic acid in the reaction mixture is in the range from 1:1 to 15:1, the reaction mixture suitably having a molar excess of the olefin reactant with respect to the aliphatic mono-carboxylic acid reactant, and the reaction being carried out at a temperature in the range from 150-200oC and at a reaction pressure of at least 400 KPa, and the reaction mixture being optionally dosed with a di-ether suitably in the range from 1 to 6 mole% based on the total reaction mixture comprising the olefin, the aliphatic carboxylic acid, water and di-ether. 2. A Process as claimed in claim 1, wherein the amount of water added is in the range from 1 to 7 mole% based on the total of the olefin, aliphatic mono-carboxylic acid and water. 3. A process as claimed in claim 1, wherein the amount of water added is the range from 1 to 5 mole% based on the total of the olefin, aliphatic mono-carboxylic acid and water. 4. A process as claimed in claim 3, wherein the siliceous support is derived from an amorphous, non-porous synthetic silica. 5. A process as claimed in claim 3, wherein the siliceous support is derived from fumed silica produced by flame hydrolysis of SiCl4. 6. A process as claimed in claim 3, wherein the silica support is in the form of pellets or beads or are globular in shape having an average particle diameter in the range from 2 to 10 mm, a pore volume in the range from 0.3-1.2 ml/g, a crush strength of at least 2Kg force and a bulk density of at least 380 g/1. 7. A process as claimed in claim 3, wherein the siliceous support has at least 99% w/w purity. 8. A process as claimed in claim 3, wherein the siliceous support is a pelleted silica support which has an average bulk density of about 0.39 g/ml, an average pore volume of about 1.15 ml/g and an average particle size ranging from about 0.1-3.5 mm. 9. A process as claimed in claim 8, wherein the pelleted silica support is used as such or after crushing to an average particle size in the range from 0.5-2 mm to support the heteropolyacid catalyst. 10. A process as claimed in claim 1 wherein the heteropolyacids used in the said catalyst is selected from the free acids and co- ordination-type salts thereof in which the anion is a complex, high molecular weight entity and comprises 2-18 oxygen-linked polyvalent metal peripheral atoms surrounding in a symmetrical manner a central atom or ion from Groups I-VIII in the Periodic Table of Elements. 11. A process as claimed in claim 10, wherein the peripheral atom is one or more of molybdenum, tungsten, vanadium, niobium and tantalum and the central atom or ion is selected from silicon; phosphorus; cupric ions; divalent beryllium zinc, cobalt or nickel ions; trivalent boron, aluminium, gallium, iron, cerium, arsenic, antimony, phosphorus, bismuth, chromium or rhodium ions; tetravalent silicon, germanium, tin, titanium, zirconium, vanadium, sulphur, tellurium, manganese nickel, platinum, thorium, hafnium, cerium ions an other rare earth ions; pentavalent phosphorus, arsenic, vanadium, antimony ions, hexavalent tellurium ions; and heptavalent iodine ions. 12. A process as claimed in claim 1, wherein the heteropolyacids have a molecular weight such as in the range from 700-8500 and include dimeric complexes. 13. A process as claimed in claim 1, wherein the heteropolyacid comprises at least one of the following compounds: 12-tungstophosphoric acid - H3[PW12O40].xH20 12-molybdophosphoric acid - H3[PMo12O40].xH2O ].xH20 12-tungstosilicic acid - H3[SiW12O40].xH2O 12-molybdosilicic acid - H4[SiMo12O40].xH2O Potassium tungstophosphate - Ke[P2W18O62]-xHaO Sodium molybdophosphate - Na3[PMo12O40].xH2O Ammonium monybdodiphosphate - (NH4)6[P2Mo18O62].xH2O Sodium tungstonickelate - Na4NiW6O24H6].xH2O Ammonium molybdodicobaltate - (NH4)[Co2Mo10O36].xH2O Cesium hydrogen tungstosilicate - CsaHfSiW 12040].xH2O Potassium molybdodivanado phosphate - K5[PMoV2O40].xH2O 14. A process as claimed in claim 3, wherein the amount of heteropolyacid deposited/impregnated on the support for use in the esterification reaction is in the range from 10 to 60% by weight based on the total weight of the heteropolyacid and the support. 15. A process as claimed in claim 1, wherein the aliphatic mono- carboxylic acid reactant is acetic acid. 16. A process as claimed in claim 1 wherein the mole ratio of olefin to the lower carboxylic acid in the reaction mixture is in the range from 10:1 to 14:1. 17. A process as claimed in claim 1, wherein the reaction is carried out in the vapour phase above the dew point of the reactor contents comprising the reactant acid, any alcohol formed in situ, the product ester and water. 18. A process as claimed in claim 1, wherein the supported heteropolyacid catalyst is used as a fixed bed which is in the form of a packed column. 19. A process as claimed in claim 1, wherein the vapour of the reactant olefins and acids are passed over the catalyst at a Gas Hourly Space Velocity in the range of 100 to 5000 per hour. 20. A process as claimed in claim 1, wherein the di-ether is diethyl ether. 21. A process as claimed in claim 1, wherein the di-ether is an unsymmetrical ether. 22. A process for the production of lower aliphatic esters substantially as herein described with reference to the foregoing examples.

Documents:

2077-del-1996-abstract.pdf

2077-del-1996-claims.pdf

2077-del-1996-correspondence-others.pdf

2077-del-1996-correspondence-po.pdf

2077-del-1996-description (complete).pdf

2077-del-1996-form-1.pdf

2077-del-1996-form-13.pdf

2077-del-1996-form-19.pdf

2077-del-1996-form-2.pdf

2077-del-1996-form-29.pdf

2077-del-1996-form-3.pdf

2077-del-1996-form-4.pdf

2077-del-1996-gpa.pdf

2077-del-1996-petition-137.pdf

2077-del-1996-petition-138.pdf