Title of Invention | AN IMPROVED INHALER |
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Abstract | This insulin (protein) inhaler has a separate drug and propellant storage to avoid inactivation of proteins. The device has a body (7) with a drug (insulin vial) in a reservoir (2) with a piston (3) and a dose counter (12) to deposit the insulin in spray path. Propellant in another can (9) evaporates and sprays the insulin. The body has a long slender mouthpiece (6) widening at its end. The needed drug is deposited in spray path (11), inhaler is kept in mouth and inhaled. The propellant can (9) is pressed. The drug is back sprayed into lungs for absorption. The inhaler gives insulin spray at back of throat with no mouth coating, reliably delivers drugs to lungs for good effect even for children and elders. The dose counter displays the dose and time for correct monitoring. All proteins can be sprayed too for direct lung deposit. |
Full Text | This invention is a novel inhaler for delivering drugs as hormones [e.g. insulin], peptides and proteins[e.g.surfactants] directly to lungs, reliably, efficiently for the first time. Inhalers available now, deliver aerosol drugs to lungs for treatment of asthma, have drugs dissolved in solvents, propellants [HFA or CFC]. Propellants inactivate hormones and proteins and will not work! Also, existing inhalers are bad in design, with no coordination help, too big size [not for kids], difficult to train and use and waste drugs as mouth spray with only 10% efficiency! Existing inhalers are not made for hormone delivery. The new inhaler is smaller in size, has a different air path, with a an air inlet, a alerting whistle [sound] or rotating vanes [visual] to coordinate spray release, a longer mouth piece with jet spray nozzle. The air inlet has a cover, with adjustable opening for deep, slow inhalation, not present in existing inhalers. The alert [sound or visual] alert helps to time the trigger of spray correctly. The spray rod of the spray canister,[ canister has only, the propellant and stabilizers ] deposits a small volume of the propellant in the spray path inside the tube. The spry path then receives the needed drug separately and opens in a jet nozzle at the back of mouth piece! A preloaded syringe with a calibrated piston, deposits the needed dosage in the spray path behind the spray rod. To use, the piston is worked to deposit the needed dosage in the spray path. The inhaler is kept in the mouth, inhaled. The alert helps to time the trigger the spray, spray can is pressed. The propellant in the spray path explosively evaporates, spraying the drug into the wind passages for absorption and action. New dose can be given by adjusting the piston rod if needed. The inhaler has a different spray path, different structure. The alert helps to time the spray release by better coordination for effective delivery. The longer mouth piece with the jet at the back of mouth [existing inhalers deliver the spray outside the lips], decreases the mouth wastage. Smaller size makes it useful and easy for kids. The inhaler has for the first time, separated the drug and the ptopcllant with no damage to the drug but effectivecly sprays the drug direct to the lungs. The drug dose is adjustable too. The inhaler is compact and easy to carry. The inhaler avoids the defects of the existing models with increased efficiency. WE CLAIM: 1. An improved mouth inhaler comprising a body with a long mouthpiece and drug vial part, the said drug vial part has the drug in a vial (2) provided with a piston (3), the said vial fitting a spray path (11), the said spray path has a propellant can (9) with a spray rod on one end and ending in a jet nozzle(8), the said jet nozzle is placed in the outside end of the said long slender diverging mouthpiece(6), the said long mouth piece back spraying into the air passages when inhaled . 2. An improved mouth inhaler as claimed in claim 1 wherein, the said piston (3) has a rotating knob (10) at the top, the said knob engages and rotates a dose counter (12) displaying the dose used. 3. An improved mouth inhaler as claimed in claim 1 wherein, the spray path comprises at one end a propellant can(9) with a spray rod at, the drug insulin vial joining in the middle, the said spray path ending in a jet nozzle (8) of the mouthpiece. 4. An improved mouth inhaler as claimed in claim 1 wherein the said drug vial and the propellant can is placed perpendicular to the long axis of mouthpiece. 5. An improved mouth inhaler as claimed in claim 1, wherein the drug vial and propellant can are placed along the long axis of mouthpiece. 6. An improved mouth inhaler as claimed in claim 1 wherein the body, mouthpiece are made of transparent plastic for visual clue. 7. An improved mouth inhaler as claimed in claim 1 wherein the propellant can has a metal can with a crimped cap covering mouth of can and a valve in the cap. 8. An improved mouth inhaler as claimed in claim 1 wherein the drug may be single or combination of active pharmacological agents described in the specification |
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553-mas-2002 abstract-duplicate.pdf
553-mas-2002 claims-duplicate.pdf
553-mas-2002 correspondnece-others.pdf
553-mas-2002 correspondnece-po.pdf
553-mas-2002 description(compelte).pdf
553-mas-2002 description(complete)-duplicate.pdf
553-mas-2002 description(provisiolnal).pdf
553-mas-2002 drawings-duplicate.pdf
Patent Number | 201632 | ||||||||||||
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Indian Patent Application Number | 553/MAS/2002 | ||||||||||||
PG Journal Number | 08/2007 | ||||||||||||
Publication Date | 23-Feb-2007 | ||||||||||||
Grant Date | 07-Aug-2006 | ||||||||||||
Date of Filing | 23-Jul-2002 | ||||||||||||
Name of Patentee | THIRUMALAI ANANDAMPILLAI APARNA, | ||||||||||||
Applicant Address | 19. 1ST STREET, PARTHASARATHY NAGAR, ADAMBAKKAM, CHENNAI-600 088 | ||||||||||||
Inventors:
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PCT International Classification Number | A61M15/00 | ||||||||||||
PCT International Application Number | N/A | ||||||||||||
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PCT Conventions:
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