Title of Invention	HOLLOW FIBER MEMBRANE SEPARATION DEVICE
Abstract	The present invention refers to a hollow fiber membrane separation device (10) with two flow spaces, of which a first space is formed by the capillary tube passages of a hollow- fiber bundle (14) cast at its ends into a sealing compound (16), and a second space is formed by a housing (12) enclosing the fiber bundle (14), wherein the first space is sealed off by caps (18), placed on the sealing compound (16), with seals running over the peripheral areas of the sealing compounds (16), and wherein the housing (12), into which the hollow-fiber bundle (14) is drawn, at each end of its casing has tooth-like or pinnacle- like projections (22) formed by axial notches or indentations running out freely. According to the invention, the housing (12) has, between the tooth-like or pinnacle-like projections (22), extensions (26) extending from said projections (22) and extending to the adjacent tooth-like or pinnacle like projection (22).

Title of Invention

HOLLOW FIBER MEMBRANE SEPARATION DEVICE

Abstract

The present invention refers to a hollow fiber membrane separation device (10) with two flow spaces, of which a first space is formed by the capillary tube passages of a hollow- fiber bundle (14) cast at its ends into a sealing compound (16), and a second space is formed by a housing (12) enclosing the fiber bundle (14), wherein the first space is sealed off by caps (18), placed on the sealing compound (16), with seals running over the peripheral areas of the sealing compounds (16), and wherein the housing (12), into which the hollow-fiber bundle (14) is drawn, at each end of its casing has tooth-like or pinnacle- like projections (22) formed by axial notches or indentations running out freely. According to the invention, the housing (12) has, between the tooth-like or pinnacle-like projections (22), extensions (26) extending from said projections (22) and extending to the adjacent tooth-like or pinnacle like projection (22).

Full Text	Fresenius Medical Care Deutschland GmbH D-61352 Bad Homburg v.d.H. Hollow Fiber Membrane Separation Device The present invention refers to a hollow fiber membrane separation device according to the generic part of claim 1. Hollow fiber membrane separation devices of said kind are for instance known from EP-A-0 844 015. In said hollow fiber membrane separation devices, two flow spaces are formed, of which a first space is formed by the capillary tube passages of a hollow-fiber bundle cast at its ends into a sealing compound, and a second space is formed by a housing enclosing the fiber bundle. The first space is sealed off by caps, placed on the sealing compounds, with seals running over the peripheral areas of the sealing compounds. The respective hollow-fiber bundle is drawn into the housing. At each end of its casing, the housing has tooth-like or pinnacle-like projections formed by axial notches or indentations running out freely. The outer areas of the projections are embedded in the sealing compounds so that the free inner areas of the notches or indentations form flow passages for the fluid. Since the housing, which is pipe-section-shaped and is preferably provided with a circular cross-section, consists of a material having elastic properties, such as polycarbonate, wreath-shaped edges consisting of flexible tongues are formed by the notches or indentations, said edges being at least partially enclosed by the sealing compound. When the sealing compound hardens to form disks, said disks can shrink essentially free of stress, wherein the flexible tongues offer no significant resistance to this shrinking. Thereby, the disks formed by the sealing compounds are firmly joined to the ends of the tubular housing so that the two flow spaces can then be reliably separated from one another by the two caps overlapping one another, with the appropriate sealing means. Said housings which are formed with the tooth-like or pinnacle-like projections have, however, the drawback that, during the manufacture of the hollow fiber membrane separation device, individual hollow fibers or hollow-fiber bundles can press through through the gaps of the axially directed pinnacles. Consequently, the outer hollow fibers or hollow-fiber bundles can protrude out in the gap between the tooth-like or pinnacle-like projections. This is inconvenient during the manufacturing process. Therefore, it is the object of the present invention to further develop a hollow fiber membrane separation device of the generic type such that it can be manufactured in a simpler way and free of troubles. The solution of said object is a new design of the housing of the hollow fiber membrane separation device according to the combination of the features of claim 1. Starting out from a hollow fiber membrane separation device of the above indicated generic type, the housing of this hollow fiber membrane separation device has extensions between the tooth-like or pinnacle-like projections, said extensions extending from said projections and extending to the adjacent tooth-like or pinnacle- like projection. The extensions between the tooth-like or pinnacle-like projections form cross-struts, so to speak, which prevent a passing through of the outer hollow fibers of the hollow-fiber bundle through the gaps between two adjacent tooth-like or pinnacle-like projections. Said extensions extend from a tooth-like or pinnacle-like projection. In a first aspect of the invention, two adjacent pinnacles are connected by means of the extensions, wherein the extensions have such a geometrical design (e.g. wavelike or zigzagged) that they are no hindrance to a change of distance between two pinnacles or to their moveability. In a second aspect of the invention, the extensions are not connected to an adjacent projection. Both aspects of the invention guarantee the desired elasticity which serves to form a stress-free connection with the shrinking sealing compound. Advantageous further developments of the invention result from the subclaims following the main claim. Accordingly, the extensions extending from the projections are preferably formed as arch-shaped or sickle-shaped hooks. Said sickle-shaped hooks bring about an even better connection with the sealing compound surrounding the projections. The risk of breaking of the material is additionally clearly reduced. According to a particularly advantageous further development of the invention, over the height of a tooth-like or pinnacle-like projection and extending therefrom two extensions are branched towards each side. The housing can be formed in one piece by injection moulding of a flexible plastic material. BRIEF DESCRIPTION OF THE ACCOMPANYING DRAWING Further features, details and advantages of the invention result from the embodiment represented in the drawing, wherein Fig. 1 shows a longitudinal section through one side of the inventive hollow fiber membrane separation device; Fig. 2 shows a detail of an end part of the housing of the hollow fiber membrane separation device; Fig. 3 shows a detail of the hollow fiber membrane separation device housing; and Fig. 4 Fig. 5 shows representations of the housing of the hollow fiber membrane separation device prior to the insertion of the fiber bundle and prior to the mounting of the caps. The hollow fiber membrane separation device 10 consists of a pipe-section-shaped housing 12 made of plastic material, for instance polycarbonate. A hollow- fiber bundle is inserted into the housing. The ends of said hollow fiber membrane bundle 14 are embedded in a sealing compound 16, for instance consisting of PU, which has a disk shape after its hardening. By means of the sealing compound 16, the hollow fibers 14 are joined to the housing 12. A cap 18 is placed on the housing, said cap being sealed off by means of a seal 20. The exact structure and the function of such hollow fiber membrane separation devices have already been described in detail in EP-A-0 844 015 which is enclosed herewith by reference. At each end of its casing, the pipe-section-shaped housing 12 has axial notches or indentations running out freely which are formed between tooth-like or pinnacle-like projections 22 (see figures 1 through 5). The gap 24 existing between the pinnacles 22 is bridged according to the present invention by extensions 26 extending from the projections 22. As can be seen in particular in figures 2 and 3, said extensions are formed as arch-shaped or sickle-shaped hooks which do not touch the adjacent tooth-like or pinnacle-like projections 22. In the embodiment represented here, two extensions 26 being arranged one above the other are arranged on each side of the projection 22. Due to said arrangement, an intensive connection with the sealing compound (see figure 1) is obtained. Due to the maintained flexibility between the adjacent tooth-like or pinnacle-like projections, which are precisely not connected with each other by means of the extensions 26, a stress-free connection with the strongly shrinking sealing material made of polyurethane can be formed. During the manufacturing process, the hollow fiber bundles 16 are introduced into the housing 12. A protruding of the individual hollow fibers from the gap between the projections 22 can be reliably avoided by the extensions 26 provided according to the invention. Moreover, the sickle-shaped design of the extensions 26 renders possible a simple and cost-advantageous design of the injection mould, as said geometrical form can be forcibly removed from the mould in axial direction in one step. In particular due to the fact that the extensions 26 are relatively flexible and can bend in the direction of the tooth-like or pinnacle-like projection also during removal from the mould, they can be manufactured by means of an injection mould despite the fact that in the final state they represent an undercut. WE CLAIM 1. Hollow fiber membrane separation device (10) with two flow spaces, of which a first space is formed by the capillary tube passages of a hollow-fiber bundle (14) cast at its ends into a sealing compound (16), and a second space is formed by a housing (12) enclosing the fiber bundle (14), wherein the first space is sealed off by caps (18) placed on the sealing compounds (16), and wherein the housing (12), into which the hollow-fiber bundle (14) is drawn, at each end of its casing has tooth-like or pinnacle-like projections (22) formed by axial notches or indentations running out freely, characterized in that, between the tooth-like or pinnacle-like projections (22), the housing (12) has extensions (26) extending from said projections (22) and extending to the adjacent tooth-like or pinnacle-like projection (22). 2. Hollow fiber membrane separation device as claimed in claim 1, wherein the extensions are formed as arch-shaped or sickle-shaped hooks. 3. Hollow fiber membrane separation device as claimed in claim 1 or 2, wherein over the height of a tooth-like or pinnacle-like projection and extending therefrom two extensions branch towards each side. 4. Hollow fiber membrane separation device as claimed in anyone of claims 1 through 3, wherein the extensions extending from the tooth-like or pinnacle-like projections are not connected to the adjacent tooth-like or pinnacle-like projections. 5. Hollow fiber membrane separation device as claimed in anyone of claims 1 through 3, wherein the extensions extending from the tooth-like or pinnacle-like projections are connected to the adjacent tooth-like or pinnacle-like projections. 6. Hollow fiber membrane separation device as claimed in anyone of claims 1 through 5, wherein the housing is made in one piece by injection moulding of a flexible plastic material. 7. Housing of a hollow fiber membrane separation device as claimed in anyone of claims 1 through 6, comprising between its tooth-like or pinnacle-like projections provided at its ends, extensions respectively extending from said projections and each extending to the adjacent tooth-like or pinnacle-like projection. ABSTRACT HOLLOW FIBER MEMBRANE SEPARATION DEVICE The present invention refers to a hollow fiber membrane separation device (10) with two flow spaces, of which a first space is formed by the capillary tube passages of a hollow- fiber bundle (14) cast at its ends into a sealing compound (16), and a second space is formed by a housing (12) enclosing the fiber bundle (14), wherein the first space is sealed off by caps (18), placed on the sealing compound (16), with seals running over the peripheral areas of the sealing compounds (16), and wherein the housing (12), into which the hollow-fiber bundle (14) is drawn, at each end of its casing has tooth-like or pinnacle- like projections (22) formed by axial notches or indentations running out freely. According to the invention, the housing (12) has, between the tooth-like or pinnacle-like projections (22), extensions (26) extending from said projections (22) and extending to the adjacent tooth-like or pinnacle like projection (22).

Full Text

Fresenius Medical Care Deutschland GmbH
D-61352 Bad Homburg v.d.H.
Hollow Fiber Membrane Separation Device
The present invention refers to a hollow fiber membrane separation device
according to the generic part of claim 1.
Hollow fiber membrane separation devices of said kind are for instance
known from EP-A-0 844 015. In said hollow fiber membrane separation devices,
two flow spaces are formed, of which a first space is formed by the capillary tube
passages of a hollow-fiber bundle cast at its ends into a sealing compound, and a
second space is formed by a housing enclosing the fiber bundle. The first space is
sealed off by caps, placed on the sealing compounds, with seals running over the
peripheral areas of the sealing compounds. The respective hollow-fiber bundle is
drawn into the housing. At each end of its casing, the housing has tooth-like or
pinnacle-like projections formed by axial notches or indentations running out freely.
The outer areas of the projections are embedded in the sealing compounds so that
the free inner areas of the notches or indentations form flow passages for the fluid.
Since the housing, which is pipe-section-shaped and is preferably provided
with a circular cross-section, consists of a material having elastic properties, such
as polycarbonate, wreath-shaped edges consisting of flexible tongues are formed
by the notches or indentations, said edges being at least partially enclosed by the
sealing compound. When the sealing compound hardens to form disks, said disks
can shrink essentially free of stress, wherein the flexible tongues offer no significant
resistance to this shrinking. Thereby, the disks formed by the sealing compounds
are firmly joined to the ends of the tubular housing so that the two flow spaces can
then be reliably separated from one another by the two caps overlapping one
another, with the appropriate sealing means.

Said housings which are formed with the tooth-like or pinnacle-like
projections have, however, the drawback that, during the manufacture of the hollow
fiber membrane separation device, individual hollow fibers or hollow-fiber bundles
can press through through the gaps of the axially directed pinnacles. Consequently,
the outer hollow fibers or hollow-fiber bundles can protrude out in the gap between
the tooth-like or pinnacle-like projections. This is inconvenient during the
manufacturing process.
Therefore, it is the object of the present invention to further develop a hollow
fiber membrane separation device of the generic type such that it can be
manufactured in a simpler way and free of troubles.
The solution of said object is a new design of the housing of the hollow fiber
membrane separation device according to the combination of the features of claim
1. Starting out from a hollow fiber membrane separation device of the above
indicated generic type, the housing of this hollow fiber membrane separation device
has extensions between the tooth-like or pinnacle-like projections, said extensions
extending from said projections and extending to the adjacent tooth-like or pinnacle-
like projection.
The extensions between the tooth-like or pinnacle-like projections form
cross-struts, so to speak, which prevent a passing through of the outer hollow fibers
of the hollow-fiber bundle through the gaps between two adjacent tooth-like or
pinnacle-like projections. Said extensions extend from a tooth-like or pinnacle-like
projection. In a first aspect of the invention, two adjacent pinnacles are connected
by means of the extensions, wherein the extensions have such a geometrical
design (e.g. wavelike or zigzagged) that they are no hindrance to a change of
distance between two pinnacles or to their moveability. In a second aspect of the
invention, the extensions are not connected to an adjacent projection. Both aspects
of the invention guarantee the desired elasticity which serves to form a stress-free
connection with the shrinking sealing compound.

Advantageous further developments of the invention result from the subclaims
following the main claim. Accordingly, the extensions extending from the projections are
preferably formed as arch-shaped or sickle-shaped hooks. Said sickle-shaped hooks bring
about an even better connection with the sealing compound surrounding the projections.
The risk of breaking of the material is additionally clearly reduced.
According to a particularly advantageous further development of the invention, over
the height of a tooth-like or pinnacle-like projection and extending therefrom two
extensions are branched towards each side.
The housing can be formed in one piece by injection moulding of a flexible plastic
material.
BRIEF DESCRIPTION OF THE ACCOMPANYING DRAWING
Further features, details and advantages of the invention result from the
embodiment represented in the drawing, wherein
Fig. 1 shows a longitudinal section through one side of the inventive hollow fiber
membrane separation device;
Fig. 2 shows a detail of an end part of the housing of the hollow fiber membrane
separation device;
Fig. 3 shows a detail of the hollow fiber membrane separation device housing; and
Fig. 4
Fig. 5 shows representations of the housing of the hollow fiber membrane
separation device prior to the insertion of the fiber bundle and prior to the
mounting of the caps.
The hollow fiber membrane separation device 10 consists of a pipe-section-shaped
housing 12 made of plastic material, for instance polycarbonate. A hollow-

fiber bundle is inserted into the housing. The ends of said hollow fiber membrane
bundle 14 are embedded in a sealing compound 16, for instance consisting of PU,
which has a disk shape after its hardening. By means of the sealing compound 16,
the hollow fibers 14 are joined to the housing 12.
A cap 18 is placed on the housing, said cap being sealed off by means of a
seal 20.
The exact structure and the function of such hollow fiber membrane
separation devices have already been described in detail in EP-A-0 844 015 which
is enclosed herewith by reference.
At each end of its casing, the pipe-section-shaped housing 12 has axial
notches or indentations running out freely which are formed between tooth-like or
pinnacle-like projections 22 (see figures 1 through 5).
The gap 24 existing between the pinnacles 22 is bridged according to the
present invention by extensions 26 extending from the projections 22. As can be
seen in particular in figures 2 and 3, said extensions are formed as arch-shaped or
sickle-shaped hooks which do not touch the adjacent tooth-like or pinnacle-like
projections 22. In the embodiment represented here, two extensions 26 being
arranged one above the other are arranged on each side of the projection 22. Due
to said arrangement, an intensive connection with the sealing compound (see figure
1) is obtained. Due to the maintained flexibility between the adjacent tooth-like or
pinnacle-like projections, which are precisely not connected with each other by
means of the extensions 26, a stress-free connection with the strongly shrinking
sealing material made of polyurethane can be formed.
During the manufacturing process, the hollow fiber bundles 16 are introduced
into the housing 12. A protruding of the individual hollow fibers from the gap
between the projections 22 can be reliably avoided by the extensions 26 provided
according to the invention.

Moreover, the sickle-shaped design of the extensions 26 renders possible a
simple and cost-advantageous design of the injection mould, as said geometrical
form can be forcibly removed from the mould in axial direction in one step. In
particular due to the fact that the extensions 26 are relatively flexible and can bend
in the direction of the tooth-like or pinnacle-like projection also during removal from
the mould, they can be manufactured by means of an injection mould despite the
fact that in the final state they represent an undercut.

WE CLAIM
1. Hollow fiber membrane separation device (10) with two flow spaces, of which a first
space is formed by the capillary tube passages of a hollow-fiber bundle (14) cast at
its ends into a sealing compound (16), and a second space is formed by a housing
(12) enclosing the fiber bundle (14), wherein the first space is sealed off by caps
(18) placed on the sealing compounds (16), and wherein the housing (12), into
which the hollow-fiber bundle (14) is drawn, at each end of its casing has tooth-like
or pinnacle-like projections (22) formed by axial notches or indentations running out
freely,
characterized in
that, between the tooth-like or pinnacle-like projections (22), the housing (12) has
extensions (26) extending from said projections (22) and extending to the adjacent
tooth-like or pinnacle-like projection (22).
2. Hollow fiber membrane separation device as claimed in claim 1, wherein the
extensions are formed as arch-shaped or sickle-shaped hooks.
3. Hollow fiber membrane separation device as claimed in claim 1 or 2, wherein over
the height of a tooth-like or pinnacle-like projection and extending therefrom two
extensions branch towards each side.
4. Hollow fiber membrane separation device as claimed in anyone of claims 1 through
3, wherein the extensions extending from the tooth-like or pinnacle-like projections
are not connected to the adjacent tooth-like or pinnacle-like projections.
5. Hollow fiber membrane separation device as claimed in anyone of claims 1 through
3, wherein the extensions extending from the tooth-like or

pinnacle-like projections are connected to the adjacent tooth-like or pinnacle-like
projections.
6. Hollow fiber membrane separation device as claimed in anyone of claims 1 through
5, wherein the housing is made in one piece by injection moulding of a flexible
plastic material.
7. Housing of a hollow fiber membrane separation device as claimed in anyone of
claims 1 through 6, comprising between its tooth-like or pinnacle-like projections
provided at its ends, extensions respectively extending from said projections and
each extending to the adjacent tooth-like or pinnacle-like projection.

ABSTRACT

HOLLOW FIBER MEMBRANE SEPARATION DEVICE
The present invention refers to a hollow fiber membrane separation device (10) with two
flow spaces, of which a first space is formed by the capillary tube passages of a hollow-
fiber bundle (14) cast at its ends into a sealing compound (16), and a second space is
formed by a housing (12) enclosing the fiber bundle (14), wherein the first space is sealed
off by caps (18), placed on the sealing compound (16), with seals running over the
peripheral areas of the sealing compounds (16), and wherein the housing (12), into which
the hollow-fiber bundle (14) is drawn, at each end of its casing has tooth-like or pinnacle-
like projections (22) formed by axial notches or indentations running out freely. According
to the invention, the housing (12) has, between the tooth-like or pinnacle-like projections
(22), extensions (26) extending from said projections (22) and extending to the adjacent
tooth-like or pinnacle like projection (22).

Documents:

01053-kolnp-2008-abstract.pdf

01053-kolnp-2008-claims.pdf

01053-kolnp-2008-correspondence others.pdf

01053-kolnp-2008-description complete.pdf

01053-kolnp-2008-drawings.pdf

01053-kolnp-2008-form 1.pdf

01053-kolnp-2008-form 2.pdf

01053-kolnp-2008-form 3.pdf

01053-kolnp-2008-form 5.pdf

01053-kolnp-2008-international exm report.pdf

01053-kolnp-2008-international publication.pdf

01053-kolnp-2008-international search report.pdf

01053-kolnp-2008-pct priority document notification.pdf

01053-kolnp-2008-pct request form.pdf

1053-KOLNP-2008-(01-11-2012)-CORRESPONDENCE.pdf

1053-KOLNP-2008-(17-05-2013)-ABSTRACT.pdf

1053-KOLNP-2008-(17-05-2013)-ANNEXURE TO FORM 3.pdf

1053-KOLNP-2008-(17-05-2013)-CLAIMS.pdf

1053-KOLNP-2008-(17-05-2013)-CORRESPONDENCE.pdf

1053-KOLNP-2008-(17-05-2013)-OTHERS.pdf

1053-KOLNP-2008-(17-05-2013)-PETITION UNDER RULE 137.pdf

1053-KOLNP-2008-CORRESPONDENCE 1.1.pdf

1053-KOLNP-2008-CORRESPONDENCE OTHERS-1.1.pdf

1053-KOLNP-2008-CORRESPONDENCE.pdf

1053-KOLNP-2008-EXAMINATION REPORT.pdf

1053-KOLNP-2008-FORM 18-1.1.pdf

1053-KOLNP-2008-FORM 18.pdf

1053-KOLNP-2008-FORM 26.pdf

1053-KOLNP-2008-GRANTED-ABSTRACT.pdf

1053-KOLNP-2008-GRANTED-CLAIMS.pdf

1053-KOLNP-2008-GRANTED-DESCRIPTION (COMPLETE).pdf

1053-KOLNP-2008-GRANTED-DRAWINGS.pdf

1053-KOLNP-2008-GRANTED-FORM 1.pdf

1053-KOLNP-2008-GRANTED-FORM 2.pdf

1053-KOLNP-2008-GRANTED-FORM 3.pdf

1053-KOLNP-2008-GRANTED-FORM 5.pdf

1053-KOLNP-2008-GRANTED-SPECIFICATION-COMPLETE.pdf

1053-KOLNP-2008-INTERNATIONAL PUBLICATION.pdf

1053-KOLNP-2008-INTERNATIONAL SEARCH REPORT & OTHERS.pdf

1053-KOLNP-2008-OTHERS.pdf

1053-KOLNP-2008-PA.pdf

1053-KOLNP-2008-PETITION UNDER RULE 137.pdf

1053-KOLNP-2008-REPLY TO EXAMINATION REPORT.pdf

1053-KOLNP-2008-TRANSLATED COPY OF PRIORITY DOCUMENT.pdf

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Patent Number

258638

Indian Patent Application Number

1053/KOLNP/2008

PG Journal Number

05/2014

Publication Date

31-Jan-2014

Grant Date

27-Jan-2014

Date of Filing

11-Mar-2008

Name of Patentee

FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

Applicant Address

ELSE-KRONER-STRASSE 1, 61352 BAD HOMBURG V.D.H.

Inventors:

#	Inventor's Name	Inventor's Address
1	WITTHAUS, FRIEDRICH	ZUM GEHREN 10, 66640 NAMBORN
2	BREITH, GERHARD	AM STEINEN 8A, 66606 ST. WENDEL

PCT International Classification Number

B01D 63/02

PCT International Application Number

PCT/EP2006/005507

PCT International Filing date

2006-06-08

PCT Conventions:

#	PCT Application Number	Date of Convention	Priority Country
1	10 2005 043 321.9	2005-09-12	Germany