| Title of Invention | “ANTI-MYOSTATIN ANTIBODIES” |
|---|---|
| Abstract | A neutralizing epitope is identified within amino acids 40-64 of the mature form of human myostatin. Antibodies that bind this epitope with high affinity preferentially bind GDF-8 over GDF-11 and may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen-binding fragments thereof. The antibodies of the invention are useful for increasing muscle mass, increasing bone density, or for the treatment of various disorders in mammalian and avian species. |
| Full Text | The invention is in the field of medicine, particularly in the field of monoclonal antibodies against myostatin. More specifically the invention relates to high affinity chmeric,........... |
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2809-delnp-2008-Abstract-(13-12-2012).pdf
2809-delnp-2008-Claims (08-04-2008).pdf
2809-delnp-2008-Claims (26-12-2008).pdf
2809-delnp-2008-Claims-(13-12-2012).pdf
2809-delnp-2008-Claims-(28-11-2013).pdf
2809-delnp-2008-Correspondence Others-(13-12-2012).pdf
2809-delnp-2008-Correspondence Others-(19-12-2012).pdf
2809-delnp-2008-Correspondence Others-(28-11-2013).pdf
2809-DELNP-2008-Correspondence-Others-(19-05-2010).pdf
2809-delnp-2008-Form-13 (08-04-2008).pdf
2809-delnp-2008-Form-13 (26-12-2008).pdf
2809-DELNP-2008-Form-26-(19-05-2010).pdf
2809-delnp-2008-Form-3-(13-12-2012).pdf
| Patent Number | 258218 | ||||||||||||||||||
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| Indian Patent Application Number | 2809/DELNP/2008 | ||||||||||||||||||
| PG Journal Number | 51/2013 | ||||||||||||||||||
| Publication Date | 20-Dec-2013 | ||||||||||||||||||
| Grant Date | 18-Dec-2013 | ||||||||||||||||||
| Date of Filing | 04-Apr-2008 | ||||||||||||||||||
| Name of Patentee | ELI LILLY AND COMPANY | ||||||||||||||||||
| Applicant Address | Lilly Corporate Center Indianapolis Indiana 46285 US | ||||||||||||||||||
Inventors:
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| PCT International Classification Number | C07K 16/22 | ||||||||||||||||||
| PCT International Application Number | PCT/US2006/038818 | ||||||||||||||||||
| PCT International Filing date | 2006-10-05 | ||||||||||||||||||
PCT Conventions:
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