Title of Invention

INTERMEDIATES OF ARYL OF HETEROARYL FUSED IMIDOZOLE COMPOUNDS

Abstract This invention provides a compound of the formula (I): or the pharmaceutically acceptable salts thereof, wherein Y1, Y2, Y3, and Y4 are independently selected from N, CH, etc.; R1 is H, C1-8 alkyl, etc.; Q1 is a 5-12 membered monocyclic or bicyclic aromatic ring optionally containing up to 4 heteroatoms selected from O, N and S, etc.; A is a 5-6 membered monocyclic aromatic ring optionally containing up to 3 heteroatoms selected from O, N and S, etc.; B is C1-6 alkylene optionally substituted with an oxo group, etc.; W is NH, O, etc.; R2 is H, C 1-4 alkyl, etc.; Z is a 5-12 membered monocyclic or bicyclic aromatic ring optionally containing up to 3 heteroatoms selected from O, N and S, etc.; L is halo, C1-4 alkyl, etc.; m is o,1 or 2; R3 and R4 are independently selected from H and C1-4 alkyl; R5 is H, C1-4 alkyl, etc.; Q2 is a 5-12 membered monocyclic or bicyclic aromatic ring or tricyclic ring optionally containing up to 3 heteroatoms selected from O, N and S, etc. These compounds are useful for the treatment of medical conditions mediated by prostaglamndin such as pain, fever or inflammation, etc. This invention also provides a pharmaceutical composition comprising the above compound.
Full Text

Documents:

518-MUMNP-2006-ABSTRACT(18-12-2012).pdf

518-MUMNP-2006-CANADA DOCUMENT(18-12-2012).pdf

518-MUMNP-2006-CLAIMS(AMENDED)-(18-12-2012).pdf

518-mumnp-2006-claims(complete)-(8-5-2006).pdf

518-mumnp-2006-claims.pdf

518-mumnp-2006-correspondance-recieved.pdf

518-mumnp-2006-correspondence(6-1-2009).pdf

518-MUMNP-2006-CORRESPONDENCE(6-5-2009).pdf

518-MUMNP-2006-CORRESPONDENCE(9-1-2009).pdf

518-mumnp-2006-deed of assignment(9-1-2009).pdf

518-mumnp-2006-description (complete).pdf

518-mumnp-2006-description(complete)-(8-5-2006).pdf

518-MUMNP-2006-EP DOCUMENT(18-12-2012).pdf

518-MUMNP-2006-FORM 1(8-5-2006).pdf

518-mumnp-2006-form 13(6-5-2009).pdf

518-mumnp-2006-form 18(5-6-2006).pdf

518-mumnp-2006-form 2(complete)-(8-5-2006).pdf

518-mumnp-2006-form 2(title page)-(complete)-(8-5-2006).pdf

518-mumnp-2006-form 3(13-6-2006).pdf

518-MUMNP-2006-FORM 3(18-12-2012).pdf

518-mumnp-2006-form 3(8-5-2006).pdf

518-mumnp-2006-form 5(8-5-2006).pdf

518-mumnp-2006-form 6(9-1-2009).pdf

518-mumnp-2006-form-1.pdf

518-mumnp-2006-form-2.pdf

518-MUMNP-2006-JP DOCUMENT(18-12-2012).pdf

518-MUMNP-2006-OTHER DOCUMENT(9-1-2009).pdf

518-MUMNP-2006-PETITION UNDER RULE-137(18-12-2012).pdf

518-MUMNP-2006-POWER OF ATTORNEY(18-12-2012).pdf

518-mumnp-2006-power of authority(8-5-2006).pdf

518-MUMNP-2006-POWER OF AUTHORITY(9-1-2009).pdf

518-MUMNP-2006-REPLY TO EXAMINATION REPORT(18-12-2012).pdf

518-MUMNP-2006-US DOCUMENT(18-12-2012).pdf

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Patent Number 256982
Indian Patent Application Number 518/MUMNP/2006
PG Journal Number 34/2013
Publication Date 23-Aug-2013
Grant Date 21-Aug-2013
Date of Filing 08-May-2006
Name of Patentee PFIZER INC.
Applicant Address 235 EAST 42ND STREET, NEW YORK, NEW YORK 10017.
Inventors:
# Inventor's Name Inventor's Address
1 KAZUNARI NAKAO PFIZER GLOBAL RESEARCH & DEVELOPMENT, 2-AZA 5-GOCHI, TAKETOYO-CHO, CHITA-GUN, AICHI-KEN 470-2393.
2 YOSHIYUKI OKUMURA PFIZER GLOBAL RESEARCH & DEVELOPMENT, 2-AZA 5-GOCHI, TAKETOYO-CHO, CHITA-GUN, AICHI-KEN 470-2393.
3 MIYAKO MATSUMIZU PFIZER GLOBAL RESEARCH & DEVELOPMENT, 2-AZA 5-GOCHI, TAKETOYO-CHO, CHITA-GUN, AICHI-KEN 470-2393.
4 NAOMI UENO PFIZER GLOBAL RESEARCH & DEVELOPMENT, 2-AZA 5-GOCHI, TAKETOYO-CHO, CHITA-GUN, AICHI-KEN 470-2393.
5 YOSHINOBU HASHIZUME PFIZER GLOBAL RESEARCH & DEVELOPMENT, 2-AZA 5-GOCHI, TAKETOYO-CHO, CHITA-GUN, AICHI-KEN 470-2393.
6 TOMOKI KATO PFIZER GLOBAL RESEARCH & DEVELOPMENT, 2-AZA 5-GOCHI, TAKETOYO-CHO, CHITA-GUN, AICHI-KEN 470-2393.
7 AKIYOSHI KAWAI PFIZER GLOBAL RESEARCH & DEVELOPMENT, 2-AZA 5-GOCHI, TAKETOYO-CHO, CHITA-GUN, AICHI-KEN 470-2393.
8 SEIJI NUKUI PFIZER GLOBAL RESEARCH & DEVELOPMENT, 2-AZA 5-GOCHI, TAKETOYO-CHO, CHITA-GUN, AICHI-KEN 470-2393.
9 KATSUHIRO SHINJYO PFIZER GLOBAL RESEARCH & DEVELOPMENT, 2-AZA 5-GOCHI, TAKETOYO-CHO, CHITA-GUN, AICHI-KEN 470-2393.
10 KANA TANIGUCHI PFIZER GLOBAL RESEARCH & DEVELOPMENT, 2-AZA 5-GOCHI, TAKETOYO-CHO, CHITA-GUN, AICHI-KEN 470-2393.
11 YORIKO MIYAKE PFIZER GLOBAL RESEARCH & DEVELOPMENT, 2-AZA 5-GOCHI, TAKETOYO-CHO, CHITA-GUN, AICHI-KEN 470-2393.
PCT International Classification Number A61K 31/00
PCT International Application Number PCT/IB01/01940
PCT International Filing date 2001-10-15
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 60/241,825 2000-10-19 U.S.A.