Title of Invention

ARYL-AND HETEROARYL-SUBSTITUTED TETRAHYDROISOQUINOLINES OF FORMULA (I)

Abstract The compounds of the present invention are represented by the chemical structure found in Formula (I): wherein: the carbon atom designated * is in the R or S configuration; and X is a fused bicyclic carbocycle or heterocycle selected from the group consisting of benzofuranyl, benzo[b]thiophenyl, benzoisothiazolyl, benzoisoxazolyl, indazoly"1, indolyl, isoindolyl, indolizinyl, benzoimidazolyl, benzooxazolyl, benzothiazolyl, benzotriazolyl, imidazo[1,2-a]pyridinyl, pyrazolo[1,5-a]pyridinyl, [1,2,4]triazolo[4,3­a]pyridinyl, thieno[2,3-b]pyridinyl, thieno[3,2-b]pyridinyl, 1H-pyrrolo[2,3­b]pyridinyl, indenyl, indanyl, dihydrobenzocycloheptenyl, tetrahydrobenzocycloheptenyl, dihydrobenzothiophenyl, dihydrobenzofuranyl, indolinyl, naphthyl, tetrahydronaphthyl, quinolinyl, isoquinolinyl, 4H-quinolizinyl, 9aH-quinolizinyl, quinazolinyl, cinnolinyl, phthalazinyl, quinoxalinyl, benzo[1,2,3]triazinyl, benzo[1,2,4]triazinyl, 2H-chromenyl, 4H-chromenyl, and a fused bicyclic carbocycle or fused bicyclic heterocycle optionally substituted with substituents (1 to 4 in number) as defined in R14; with R1, R2, R3, R4, R5, R6, R7, R8, and R14 defined herein.
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Documents:

660-CHENP-2007 AMENDED PAGES OF SPECIFICATION 03-05-2013.pdf

660-CHENP-2007 AMENDED CLAIMS 03-05-2013.pdf

660-CHENP-2007 OTHER PATENT DOCUMENT 03-05-2013.pdf

660-CHENP-2007 FORM-3 03-05-2013.pdf

660-CHENP-2007 POWER OF ATTORNEY 03-05-2013.pdf

660-CHENP-2007 ASSIGNMENT 03-05-2013.pdf

660-CHENP-2007 FORM-1 03-05-2013.pdf

660-CHENP-2007 OTHER PATENT DOCUMENT 03-05-2013.pdf

660-CHENP-2007 AMENDED CLAIMS 29-07-2013.pdf

660-CHENP-2007 CORRESPONDENCE OTHERS 04-07-2012.pdf

660-CHENP-2007 EXAMINATION REPORT REPLY RECEIVED 03-05-2013.pdf

660-CHENP-2007 FORM-18.pdf

660-CHENP-2007 ABSTRACT.pdf

660-CHENP-2007 ASSIGNMENT.pdf

660-CHENP-2007 CLAIMS.pdf

660-CHENP-2007 CORRESPONDENCE OTHERS 17-08-2012.pdf

660-CHENP-2007 CORRESPONDENCE OTHERS 18-07-2013.pdf

660-CHENP-2007 CORRESPONDENCE OTHERS 29-07-2013.pdf

660-CHENP-2007 CORRESPONDENCE OTHERS.pdf

660-CHENP-2007 DESCRIPTION (COMPLETE).pdf

660-CHENP-2007 FORM-1.pdf

660-CHENP-2007 FORM-3.pdf

660-CHENP-2007 FORM-5.pdf

660-CHENP-2007 FORM-6 04-07-2012.pdf

660-CHENP-2007 PCT.pdf

660-CHENP-2007 POWER OF ATTORNEY 04-07-2012.pdf

660-chenp-2007 assignment 11-06-2007.pdf

660-chenp-2007 correspondence others 11-06-2007.pdf

660-chenp-2007 form-3 11-06-2007.pdf

660-CHENP-2007 OTHER DOCUMENT 04-07-2012.pdf


Patent Number 256875
Indian Patent Application Number 660/CHENP/2007
PG Journal Number 32/2013
Publication Date 09-Aug-2013
Grant Date 06-Aug-2013
Date of Filing 15-Feb-2007
Name of Patentee BRISTOL-MYERS SQUIBB COMPANY
Applicant Address LAWRENCEVILLE-PRINCETON ROAD, PRINCETON, NJ 08543-4000, USA
Inventors:
# Inventor's Name Inventor's Address
1 MOLINO, BRUCE, F 14 CYGNET CIRCLE, SLINGERLANDS, NY 12159, USA
2 LIU, SHUANG 302 POLSIINELLI DRIVE, SCHENECTADY, NY 12303, USA
3 BERKOWITZ, BARRY, A ONE SAGE LANE, FRAMINGHAM, MA 01701, USA
4 GUZZO, PETER, R 1146 MILLINGTON ROAD, NISKAYUNA, NY 12309, USA
5 BECK, JAMES, P DROP CODE 1513, INDIANAPOLIS, IN 46285, USA
6 COHEN, MARLENE 10532 COPPERGATE, CARMEL, IN 46032, USA
PCT International Classification Number C07D217/00
PCT International Application Number PCT/US05/25193
PCT International Filing date 2005-07-15
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 60/588,448 2004-07-15 U.S.A.