Title of Invention

CONTAINER WITH HOLLOW NEEDLE

Abstract The present invention relates to a container (1, 1, 1"), for the intake and release of a medicament, in particular a parenteral medicament, the container (1, 1', 1") exhibiting a one-piece integral casing (6, 6') which is sealed , except for an opening (7) for the purpose of releasing the medicament, the container (1, 1', 1") is configured in such a way that a release of the medicament is effected by alteration of at leas tone region of the casing (6, 6"), characterized in that the container exhibits a hollow needle (9, 10) in the region of the opening (7).
Full Text

Description:
The present invention relates to a container for the intake
of a medicament and the release thereof into an
administration device, to the production and use of said
container, and also to the associated administration
device. The medicaments are, for example, medicaments to
be administered parenterally, but they may also be oral or
topical medicaments. The container according to the
invention exhibits a particularly advantageous
configuration of the casing.
In the case of parenteral administration - i.e.
administration by-passing the gut of a mammal - of
medicaments, this generally takes place by injection or
infusion. The term 'injection' is understood to mean the
administration of a liquid sterile medicament by means of a
syringe and a hollow needle directly into the tissue or
vascular system, by-passing the gastro-intestinal tract.
In the case of infusion, it is a question of slow, mostly
dropwise influx of relatively large quantities of (drug-
containing) liquid into the body.
Medicaments - for example, medicaments to be administered
parenterally - are generally decanted, after their
preparation, into a container that is able to receive one
or more portions/doses. This container is designated as
the primary packing.

By way of primary packing, glass ampoules are known that
have to be opened with a special ampoule saw or that are
furnished with a predetermined breaking-point for the
purpose of opening. The contents have to be transferred
from the ampoule into a container that is suitable for the
administration, such as a syringe, for example.
Furthermore, for the most part, residual liquid has to
remain in the ampoule, since otherwise the aspiration of
air may occur disadvantageously in the course of filling
the syringe. Moreover, a later sealing of the ampoule,
with the residual liquid contained therein, is practically
impossible.
A so-called pierceable ampoule (vial) is known from the
state of the art as a further container. Said ampoule is
punctured with a syringe at a point provided for this
purpose, and the syringe is then filled with the liquid
held in the container. This process associated with this
container is very elaborate, since the ampoule cannot be
used immediately for the purpose of administration, but the
contents rather have to be transferred out of the ampoule
into a container that is suitable for the administration,
such as the aforementioned syringe. The opening or
piercing of ampoules, and a subsequent necessary transfer
into a container that is suitable for the administration,
proves to be disadvantageous, for example in emergency
situations in which administration has to be effected under-
time-pressure .
Nowadays, decanting is also effected directly into a
syringe that is furnished with a clipped-on or glued-in
cannula for the purpose of administration. By virtue of
pressure on the plunger which is movably supported in the

syringe container, the liquid is injected, out of the
container through the cannula into the place of
administration. The syringe has the disadvantage that, by
reason of the multi-part structure, it is comparatively
expensive. For the purpose of maintaining operational
capability also after a relatively long period of storage,
the plunger and the syringe container are furnished with
coatings, for example with silicone. Hence a substance is
stored and administered together with the medicament that
has nothing to do with the actual action of the medicament
and that may even have a disadvantageous effect, for
example in the case of medicaments having a high pH value.
Together with the parenteral medicaments - which in general
are decanted into ampoules, vials or ready-to-use syringes,
and also into infusion bottles or infusion bags - non-
parenterally administered medicaments are sometimes also
stored in ampoules or vials, since, for example, they have
to be mixed with water prior to administration.
From US 4,926,915 a container is known in the form of a
collapsible tube. The collapsible tube disclosed therein
represents a simplification of the ampoule or pierceable
ampoule, since a syringe can be directly attached and
filled. By way of means for connection to a collapsible
tube, a surface is proposed tapering conically inwards to a
point.
GB 8 00 455 A discloses the connection of two collapsible
tubes so as to result in a reciprocal ejection of contents.
Connection to an administration device is not provided.
US 4,926,915 A discloses, inter alia, a collapsible-tube-
shaped container with a Luer coupling for connection to an

ampoule. Connection to an administration device is
likewise not provided.
In.US 2003/00107 95 A1 a container is shown that is
configured in such a way that a triggered release of a
liquid is continued independently.
US 4,328,912 describes a collapsible container that is
capable of implementing a release of a liquid independently
by reason of a specific design of a valve.
US 2003/0015605 Al describes a container filled with a
liquid, wherein under the influence of pressure a discharge
is triggered abruptly only after an initial resistance has
been overcome.
Against the background of the disadvantages described
above, it is therefore the object of the present invention
to make available a container for the intake and release of
a medicament or, to be more exact, a container with an
associated administration device that each facilitate the
administration of a medicament and also the connection to
an administration device and that are of comparatively
simple construction.
This object is achieved by means of the container claimed
in Claim 1. Advantageous configurations will become
apparent from the dependent claims. An advantageous
production process and also an advantageous use are
subjects of the associated independent claims.
The container according to the invention for receiving and
releasing a medicament is furnished with an integral casing
which is sealed, except for an opening for the purpose of:

releasing the medicament. The container is furthermore
configured in such a way that a release of the medicament
from the opening is effected by alteration of the whole
casing or of a region of the casing. The medicament is
present, for example, in a solution or other liquid, the
viscosity of which may have been chosen to be variable.
For example, it is a question of a medicament to be
administered parenterally, orally or topically.
In accordance with the invention, the alteration of the
casing is associated with the release of the medicament.
For example, by reason of the choice of material and, in
particular, in the case of' a comparatively large-volume
casing the casing is configured to be collapsing; this
means that at the time of release of the medicament by
means of capillary forces and/or by reason of the effect of
gravity the at. least partial collapse of the casing, and
consequently alteration of the casing, occurs by reason of
the partial vacuum forming in the container.
The concept of 'integrality' is to be understood in such a
way that the casing is not of multi-part construction. The
casing is, for example, made of one material or several
materials and/or exhibits differing compositions in various
regions. In comparison with a multi-part structure, as in
the case of a plunger device, the integrality of the casing
ensures an inexpensive production of the device.
Furthermore, administration is effected in a mariner that is
particularly simple, sterile, rapid and not susceptible to
faults. By reason of the integrality, the number of
product-contacting elements or materials is reduced, for
example in comparison with a structural design having a
moving plunger, so that the compatibility with the

medicament can be ensured advantageously and comparatively
simply.
The container according to the invention further includes a
hollow needle in the region of the opening. In one
embodiment, the hollow needle serves as means for
connection to an administration device or to a container
for a medicinal liquid. By means of the hollow needle the
connection can be made quickly and securely. In the case
of the administration devices to which a liquid-conducting
connection is to be established by means of the needle, it
is a question of means for infusion or injection that, for
example, exhibit a membrane or foil which is penetrated by
the hollow needle for the purpose of emptying the container
into the administration device.
In an advantageous configuration of the device according to
the invention, it is a question of an administration device
- that is to say, an infusion or injection needle or
cannula - that serves for administering the medicament to a
patient via the opening. If the container that is used for
transport and storage is used, at the same time for the
purpose of administering the medicament, a process of
transfer from a transport container into a container that
is intended for the administration is advantageously
dispensed with.
In one configuration, the hollow needle serves for direct
administration, for example by injection. Injection is
effected - depending on the place of administration
intracutaneously, subcutaneously, intramuscularly,
intravenously, intra-arterially, intracardially, intra-
articularly, intrathecally or intralumbarly. In one
embodiment, the hollow needle is manufactured from metal -

for example, medical special steel - and is sharpened, in
order to be employed as an injection or infusion needle in
humans or animals.
According to one embodiment, the hollow needle is inserted
or glued into the casing in the region of the opening.
According to another advantageous embodiment, the casing is
formed integrally with the hollow needle. By virtue of
this, the container can be produced particularly
inexpensively. As a result, in advantageous manner no
further material comes into contact with the medicament in
the course of release of the medicament. During storage
and release, contact with the medicament is limited to one
material or one material composition. In this way it can
be ensured particularly simply that contact with materials
of the container does not have a disadvantageous effect -
for example, altering the pH value - on the medicament
contained in the container. Furthermore, in this way the
container can be produced particularly simply, cost-
effectively and rapidly, which is an advantage from the
point of view of production technology.
In another advantageous configuration of the container
according to the invention, said container is configured in
such a way that the release of the medicament is achieved
or at least triggered by pressure on at least one outer
region of the casing. For example, the casing is designed
in such a manner that a release of the medicament is
brought about by pressure of the thumb on the associated
outer region of the casing. As a result, a particularly
reproducible, dosed release of the medicament - which, for
example, is present in liquid form with highly varying
viscosity - is made possible. For example, the injection

pressure required for an injection is generated by the
pressure acting on the casing; additional means for
generating pressure - for example, a pump - can
consequently be dispensed with advantageously. For
example, the container is of tubular construction. A
pressure on the tubular casing triggers a reduction in
volume. The associated reduction in volume brings about a
displacement out of the container of the medicament
received in the container, and hence an escape and hence a
release via the opening. Depending on the chosen hardness
of the casing, the characteristic of the pressure to be
applied can be advantageously varied.
In another advantageous embodiment, the container is
configured in such a way that after the triggering of the
release by virtue of the pressure the release of the
medicament is continued independently. For example, this
is achieved by means of a configuration in which, when a
certain outer curvature is. attained, a relatively hard and
elastic casing segment jumps in spring-like manner - in
accordance with the jumping-jack principle - into the
opposite curvature, pointing into the interior of the
container, and in this way releases a precisely defined
volume of medicament by reason of the spring characteristic
of the casing segment. By virtue of this, on the one hand
an independent release is achieved, and on the other hand a
well-dosed release.
According to another advantageous embodiment, the container
exhibits a collapsible-tube-shaped casing. "Collapsible-
tube-shaped" in the sense of the invention is to be
understood in such a way that, substantially as a
consequence of the heat sealing, the container tapers to a
point at its end located opposite the opening. By virtue

of this type of configuration, a particularly easy emptying
of the container - and hence release of the medicament - is
achieved. For example, by means of a stroking movement
from the pointed end of the collapsible tube a particularly
effective - i.e. rapid and largely remainder-free -
emptying of the container can be achieved, particularly if
the medicament exhibits a high viscosity in comparison with
aqueous solutions. A collapsible tube is generated, for
example, by means of a tube in which one end is sealed by
flat heat sealing or folding, depending on the material
being used in each instance. In one configuration, the
access - existing prior to the heat sealing or folding - to
the interior of the collapsible-tube-shaped container
advantageously serves in addition as a supply option for
the filling with the medicament which is subsequently
received within the container and which is optionally
released via the opening that is provided in accordance
with the invention.
According to another advantageous embodiment, connection
means are provided for detachable connection of the hollow
needle to the container. The detachabiiity enables the
container to be detached from the administration device, in.
order, for example, to be able to attach a new filled
container quickly. For example, for the purpose of
detachable connection an extension furnished with an
external thread is provided on the container, in which
extension the opening is arranged concentrically. The
hollow needle exhibits, for example, a recess interacting
with the extension and receiving the latter. By virtue of
the internal thread provided in the recess and interacting
with the external thread, a detachable but simultaneously
liquid-tight connection between the container and the
hollow needle is achieved. The detachabiiity, according to

the configuration, of the connection between the container
and the hollow needle ensures that a container can be
easily exchanged for a filled container, as a result of
which the flexibility and rapidity of administration and
hence the user-friendliness are enhanced.
In another advantageous embodiment, the means for
connecting the opening to the administration device include
a locking means for preventing an unintentional loosening
of the connection. For example, a screw device is
furnished with a latching function which additionally
secures the screw connection in the screwed-in state by
means of a latching spring element. A loosening is
possible only after this spring action, associated with the
latching, has been overcome. An unintentional loosening of
the connection is largely prevented in this way.
According to another advantageous embodiment of the
container according to the invention, the means for
detachable connection exhibit two conically-shaped surfaces
complementary to one another. As a result, a simple and -
at the same time - sufficiently tight connection is
achieved. The container is preferably furnished with an
extension having an outer surface tapering conically to the
opening.
According to one embodiment, it is a question of a Luer
coupling (Luer cone or Luer lock). A so-called Luer
coupling is defined in ISO 594/1. In general, it is a
question of a coupling designated as male. By provision of
such a coupling on the container, several working steps are
eliminated in the course of administration of the
medicament.

According to another advantageous configuration, the
connection means are formed, at least partially, integrally
with the container. By virtue of this, the container can
be produced particularly simply, cost-effectively and
quickly, which is an advantage from the point of view of
production technology.
Integrality is achieved, for example, in a single
production step or as follows: in a first step of the
production, two pieces are produced which are subsequently
heat-sealed or joined together. The decanter is then
furnished with an integral part, in order to fill this with
the medicament. If use is. made of existing injection
moulds, a bringing-together of two parts is an advantage in
the case of a production process where plastic hoses or
laminate hoses which form the actual container are heat-
sealed onto a head part with the connection means or if the
connection means exhibit a particular complexity.
In another advantageous configuration, the container
exhibits a volume of less than 5 ml. A volume of less than
5 ml proves to be particularly advantageous, since a
container, in particular a collapsible tube., can be emptied
efficiently and uniformly in one stroke by simple pressure
with the thumb. It has become evident that, as a result,
the handling of the container, and hence the. administration
of the medicament, is particularly simple and efficient.
In another advantageous embodiment, the container consists
of synthetic material, in particular polypropylene, PE,
such as LDPE or PET. Also usable are PVC, PVF etc.
Nowadays, new, heat-sealable synthetic materials are also
being developed that can be employed advantageously for
medicaments. The choice of synthetic materials according

to the invention is restricted only to the extent that the
producibility of the container according to the invention
is guaranteed. As a result, the container can be produced
inexpensively. Furthermore, by reason of the comparatively
low heat-sealing and melting temperature, sealing of the
container after decanting has taken place can be effected
in a manner that is particularly non-damaging to the
medicament. Moreover, in this way the batch information
and/or expiry information can be easily stamped onto the
outer surface of the container. These inscriptions
accordingly have a long life.
In another advantageous embodiment, the container consists
of a laminate. As a result, there are further
compatibility options. For example, an aluminium foil
which itself does not touch the product but constitutes a
heightened oxygen barrier may be inserted into the jacket
of the container, and in this way the stability of the
product is influenced favourably. Furthermore, preprinted
labels, which for their part may again have a barrier
function, may be inserted into the jacket (in-mould
labelling). By virtue of this, even the affixing of -labels
is dispensed with, and no adhesive becomes necessary that;
could get into the product by diffusion.
According to another advantageous embodiment, the container
is designed to be at least partially transparent. As a
result, the filling-level or the emptying can be
advantageously monitored.
According to another advantageous configuration, the
container is coated. For example, the inner surface of the
casing in contact with the medicament is coated with a
chemically neutral coating such as silicon oxide. By

virtue of this, it is ensured that, by reason of the
coating, the container achieves, in this respect, glass-
like properties without exhibiting the disadvantages
associated with glass: for example, risk of injury when
opening glass ampoules and disposing of them, etc.
In another advantageous embodiment, the casing of the
container is designed to be at least partially clastic. By
virtue of this, it is ensured that when the pressure on the
casing is removed the latter is able to regain its original
shape and the container can be emptied intermittently, for
example in several similar movements executed in
succession.' As a result, emptying can be effected
particularly simply.
According to another embodiment, the means for connection
may furthermore interact with a seal intended for them, so
that a particularly easy sealing of the container according
to the invention - in contrast, for example, to the
ampoules described in the introduction - is achieved. The
seal is, for example, a separate plastic injection-moulded
part which is screwed or fitted onto the hollow needle
previously described. In another embodiment, the seal is
integrally connected to the casing and is produced together
with the container in one processing step, in order to
protect the medicament received in the container against
contamination. By virtue of this, the container together
with the seal can be produced simply and cost-effectively.
The sealing means include, for example, screw or plug-in
caps and segments that are heat-sealed onto the casing and
furnished with predetermined breaking-points.
The process according to the invention for producing the
container exhibits a step in which the container is

produced in a plastics injection-moulding step, plastics
injection-blow-moulding step or plastics extrusion-blow-
moulding step. As a result, the container can be produced
inexpensively, optionally together with the seal and/or the
means for detachable connection to the administration
devices. In another production process the jacket and the
head part are produced separately and are heat-sealed to
one another. Furthermore,' the integrality that is
advantageous for the decanter and user can be achieved by
two parts being produced separately by the manufacturer but
being already assembled (e.g. stuck together and
subsequently heat-sealed) to form one piece by said
manufacturer.

With reference to the Figures:
Figures 1a and lb show exemplary embodiments of the
container according to the invention.
Figures 2a and 2b show a form of the container according to
the invention, wherein regions of the casing are themselves
constructed in collapsing manner.
Figure la shows a first embodiment of the container 1
according to the invention with a collapsible-tube-shaped,
one-piece casing 6. A liquid (not represented) containing
a medicament {in general, a parenteral medicament) is
contained in the casing 6. The (in general, parenteral)
medicament or, to be more exact, the liquid is released
from the container 1 via the opening 4 by pressure being
exerted on the casing 6 in the region of 1, for example
with the fingers. The casing 6 is sealed in airtight and
liquid-tight manner on the side located opposite the
opening 4 by a heat seal 2 extending in plane manner, as a
result of which the collapsible-tube shape arises. The
means of connection of the opening 4 of the container to an
administration device which is not shown include a conical
extension 5 formed on the casing. The contour of said
extension is indicated in Fig. la by dashes, since it is
partially surrounded by a sleeve 3 furnished with an
internal thread, which is likewise part of the connection
means. The conical extension may have been provided
without the sleeve, and consequently forms a so-called Luer
male coupling. If the sleeve has been provided with an
internal thread, a structure arises that corresponds to a
so-called Luer-lock coupling. The conically extending
extension 3 as part of the connection means serves, with
connection of a connecting element complementary thereto,

for an infusion needle or injection needle by way of
administration device (not represented in the
illustration), in order to connect said device, on the one
hand, in liquid-conducting manner and, on the other hand,
tightly and detachably.
The opening 4 is, for example, sealed at the outlet with a
predetermined breaking-point, in which connection an
arbitrarily shaped breaking aid 7 is attached by injection
moulding, or with a directly cast-on foil or membrane
which, for example, can be penetrated with a pointed
object.
Fig. lb shows another embodiment 1' of the collapsible-
tube-shaped container according to the invention. Said
container differs from the embodiment 1, above all, by
virtue of the different design of the casing in the region
of the opening. Furthermore, the hollow needle 9 according
to the invention is shown which serves for connection of
the container to an administration device - that is to say,
for the introduction of said container into an infusion
bag, for example. The hollow needle is formed integrally
with the casing.
Figures 2a and 2b show another embodiment 1' of the
container according to the invention. Said container is
furnished with a casing 6' which at the time of release of
the medicament utilises the jumping-jack principle. In
Figure 2b the casing 6' is represented in section. The
upper half of the casing shown in the Figure jumps
elastically inwards after a certain curvature has been
exceeded after initial external pressure; this inwardly
directed spring action brings about a displacement effect
on the medicament held in the casing 6', and results in a

release of the medicament via the opening. By reason of
the predetermined spring action, a release is brought about
in reproducibly independent manner after the first,
triggering pressure on the casing 6'. Consequently the
same quantity of liquid is always ejected. In cross-
section it is evident that the upper half of the casing
fits into the other half after pressure and so is also no
longer able to spring back into its original shape.
Figure 3 shows the embodiment that is shown in Figure 1
with associated infusion needle or injection needle 10.
The connection means 12 attached to the infusion needle or
injection needle 10 exhibits an inner surface which tapers
conically inwards to a point in such a manner that it Ls
complementary to the outer surface 5 of the connection
means of the container 1. By engagement of the two
surfaces of the connection means 5, 12, a detachable
connection between the container 1 and the needle 10 is
established. This connection is additionally fixed by
means of a screw connection between the internal thread of
the casing 3 and the external thread 12 provided on the
connecting part 11 of the needle.
Figure 4 shows the use of the container 1' from Fig. 1b.
The hollow needle 9 serves for connection to an infusion
bag or infusion bottle 14, whereby a foiJ or membrane 13 of
the infusion bag or infusion bottle 14 is penetrated, in
order to introduce the medicament held in the container 1'
into the bag or bottle 14.

We Claims:
1. A container (1, 1, 1"), for the intake and release of a medicament, in particular a
parenteral medicament, the container (1, 1', 1") exhibiting a one-piece integral
casing (6, 6') which is sealed , except for an opening (7) for the purpose of releasing
the medicament, the container (1, 1', 1") is configured in such a way that a release of
the medicament is effected by alteration of at leas tone region of the casing (6, 6"),
characterized in that the container exhibits a hollow needle (9, 10) in the region of
the opening (7).
2. A container as claimed in the preceding claims, wherein the hollow needle (9) is
formed integrally with the casing (6, 6').
3. A container as claimed in the preceding claims, wherein the needle is an infusion
needle or injection needle (10) by way of administration device.
4. A container as claimed in the preceding claims, the container (1,1',1") being
configured in such a way that the release of the medicament is achieved or at least
triggered by pressure on at least one outer region of the casing (6).
5. A container (1, 1, 1") as claimed in the preceding claims, the container (1, 1, 1")
being configured in such a way that after the triggering of the release of the
medicament the release of the medicament is continued independently.
6. A container (1, 1, 1") as claimed in the preceding claims, the container (1, 1, 1")
exhibiting a collapsible-tube-shaped casing (6, 6).

7. A container (1, 1, 1") as claimed in the preceding claims, with connection means (3,
5, 11, 12] for detachable connection of the hollow needle to the container or to the
casing.
8. A container (1, 1, 1") as claimed in the preceding claims, wherein for the purpose of
detachable connection of the hollow needle (10) to the container (1, 1', 1") the
connection means (3, 5, 11, 12) exhibit two conically shaped mutually
complementary surfaces (5, 11)
9. A container (1, 1, 1") as claimed in the preceding claims, wherein for the purpose of
detachable connection of the hollow needle (10) to the container the connection
means (3, 5, 11, 12) include locking means (3, 12) for preventing unintentional
loosening.
10. A container (1, 1, 1") as claimed in the preceding claims, the container (1, 1' ,11)
exhibiting a volume between 0.5 ml to 5 ml.
11. A container (1, 1, 1") as claimed in the preceding claims, the container (1, 1', 1")
consisting of synthetic material, in particular polypropylene, PE, such as LDPE or
PET.
12. A container (1, 1, 1") as claimed in the preceding claims the container (1, 1', 1")
exhibiting a laminate.
13. A container (1, 1, 1") as claimed in the preceding claims, the container (1, 1', 1") is
partially transparent.
container (1, 1, 1") as claimed in the preceding claims, the container (1, 1', 1") is
partially coated.
15. A container (1, 1, 1") as claimed in the preceding claims, wherein the casing (6, 6') of
the container (1, 1', 1") is partially elastic.

16. A process for producing a container (1, 1, 1") as claimed in the preceding claims 1-15,
which includes an injection-moulding step, injection-blow-moulding step or
extrusion-blow-moulding step.
17. A container (1, 1, 1") as claimed in the preceding claims 1-16 for infusion or injection
of a medicament as herein substantially described with reference to Figures 1-4
accompanying the specification.


Abstract

"Container with Hollow Needle".
The present invention relates to a container (1, 1, 1"), for the intake and release of a
medicament, in particular a parenteral medicament, the container (1, 1', 1")
exhibiting a one-piece integral casing (6, 6') which is sealed , except for an opening
(7) for the purpose of releasing the medicament, the container (1, 1', 1") is
configured in such a way that a release of the medicament is effected by alteration of
at leas tone region of the casing (6, 6"), characterized in that the container exhibits a
hollow needle (9, 10) in the region of the opening (7).

Documents:

04442-kolnp-2007-abstract.pdf

04442-kolnp-2007-claims.pdf

04442-kolnp-2007-correspondence others.pdf

04442-kolnp-2007-description complete.pdf

04442-kolnp-2007-drawings.pdf

04442-kolnp-2007-form 1.pdf

04442-kolnp-2007-form 2.pdf

04442-kolnp-2007-form 3.pdf

04442-kolnp-2007-form 5.pdf

04442-kolnp-2007-international publication.pdf

04442-kolnp-2007-international search report.pdf

4442-KOLNP-2007-(22-03-2012)-ABSTRACT.pdf

4442-KOLNP-2007-(22-03-2012)-AMANDED CLAIMS.pdf

4442-KOLNP-2007-(22-03-2012)-DESCRIPTION (COMPLETE).pdf

4442-KOLNP-2007-(22-03-2012)-DRAWINGS.pdf

4442-KOLNP-2007-(22-03-2012)-EXAMINATION REPORT REPLY RECEIVED.pdf

4442-KOLNP-2007-(22-03-2012)-FORM-1.pdf

4442-KOLNP-2007-(22-03-2012)-FORM-2.pdf

4442-KOLNP-2007-(22-03-2012)-FORM-3.pdf

4442-KOLNP-2007-(22-03-2012)-OTHERS.pdf

4442-KOLNP-2007-(22-03-2012)-PETITION UNDER RULE 137.pdf

4442-KOLNP-2007-(31-07-2012)-ABSTRACT.pdf

4442-KOLNP-2007-(31-07-2012)-AMANDED CLAIMS.pdf

4442-KOLNP-2007-(31-07-2012)-CORRESPONDENCE.pdf

4442-KOLNP-2007-CORRESPONDENCE 1.1.pdf

4442-KOLNP-2007-CORRESPONDENCE-1.2.pdf

4442-KOLNP-2007-FORM 26.pdf

4442-KOLNP-2007-OTHERS.pdf

4442-KPLNP-2007-CORRESPONDENCE 1.3.pdf

4442-KPLNP-2007-EXAMINATION REPORT.pdf

4442-KPLNP-2007-FORM 18.pdf

4442-KPLNP-2007-FORM 26.pdf

4442-KPLNP-2007-FORM 3.pdf

4442-KPLNP-2007-FORM 5.pdf

4442-KPLNP-2007-GRANTED-ABSTRACT.pdf

4442-KPLNP-2007-GRANTED-CLAIMS.pdf

4442-KPLNP-2007-GRANTED-DESCRIPTION (COMPLETE).pdf

4442-KPLNP-2007-GRANTED-DRAWINGS.pdf

4442-KPLNP-2007-GRANTED-FORM 1.pdf

4442-KPLNP-2007-GRANTED-FORM 2.pdf

4442-KPLNP-2007-GRANTED-SPECIFICATION.pdf

4442-KPLNP-2007-INTERNATIONAL PUBLICATION.pdf

4442-KPLNP-2007-INTERNATIONAL SEARCH REPORT.pdf

4442-KPLNP-2007-OTHERS 1.1.pdf

4442-KPLNP-2007-REPLY TO EXAMINATION REPORT.pdf

abstract-04442-kolnp-2007.jpg


Patent Number 255466
Indian Patent Application Number 4442/KOLNP/2007
PG Journal Number 09/2013
Publication Date 01-Mar-2013
Grant Date 25-Feb-2013
Date of Filing 19-Nov-2007
Name of Patentee VIFOR (INTERNATIONAL) AG
Applicant Address RECHENSTRASSE 37 9001 ST. GALLEN
Inventors:
# Inventor's Name Inventor's Address
1 LUDWIG WEIBEL-FURER HARSCHWENDI WEST 1069 9104 WALDSTATT
2 DOMINIQUE WEIBEL-FURER HARSCHWENDI WEST 1069 9104 WALDSTATT
PCT International Classification Number A61J 1/06, B65D 1/09
PCT International Application Number PCT/EP2006/062415
PCT International Filing date 2006-05-18
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 05104386.7 2005-05-24 EPO