Title of Invention

ENCAPSULATED GAS-INSULATED SWITCHGEAR ASSEMBLY

Abstract The switchgear assembly has a polyphase design and has a gas-filled, modular encapsulation for each phase. Provided as the modules are at least one busbar (51, 52), which is guided redominantly horizontally, a circuit breaker (10) and two combineq disconnecting- earthing switches (71, 72, 73) of identical design and having ~ disconnection and grounding function. A first one (71) of the combined disconnecting-earthing switches supports a section of the busbar (51) and is connected between the busbar (51) and a first current Iterminal (11) of the circuit breaker (10). The second combined disconnecting-earthing switch (73) is connected between an outgoing feeder (60) or a further busbar of the assembly and the second current terminal (12) of the circuit breaker (10). The combined disconnecting- earthing switches (71, 72, 73) are aligned such that two drive apparatuses (81, 82, 83), which are provided for their actuation, point in the same, predominantly horizontal direction. This switchgear assembly is of compact design since the drives of the combined disconnecting-earthing switches are guided in one direction and sections of the assembly which are connected to the I combined disconnecting-earthing switches are guided in the opposite direction. If the drives point towards a control aisle of the assembly, the positions of the drives (81, 82, 83) and therefore the switching positions of the combined disconnecting-earthing switches (71, 72, 73) are visually easily accessible to the operator of the assembly.
Full Text

DESCRIPTION
Encapsulated gas-insulated switchgear assembly
TECHNICAL FIELD
The invention is based on an encapsulated gas-insulated switchgear assembly . in accordance with the precharacterizing clause of patent claim 1. This encapsulation is filled with an -insulating gas, for example nitrogen, air, sulfur hexafloride (SF6) alone or in a mixture, with a pressure of up to a few bar. The assembly is typically operated at voltages of a few hundred kV and contains as the components at least one busbar which is guided predominantly horizontally, a circuit breaker having two current terminals, of which a first current terminal can be connected to the busbar, and two disconnecting switches (combined disconnecting-earthing switches) having a disconnection and grounding function.
The combined disconnecting-earthing switches are preferably of identical design. A first one of the combined disconnecting-earthing switches supports a section of the busbar and is connected between the busbar and the first current terminal. The second combined disconnecting-earthing switch is connected between an outgoing feeder of the . assembly or a horizontally guided second busbar of the assembly and the second current terminal of the circuit breaker. The combined disconnecting-earthing switches make use of the fact that, in switchgear assemblies, the functions of disconnection and grounding are often required at the same location. Correspondingly, the combined disconnecting-earthing switches each have an encapsulating housing which is filled with insulating gas and to which a grounding contact is fixed in the interior. In addition, a disconnector contact, which is fixed to a

current conductor, and a moveable contact element, which can be displaced along an axis and can be brought into or out of engagement either with the disconnector contact or with the grounding device contact, are arranged in the housing interior. Force is applied to the moveable contact element by a drive guided through the housing. By using a single drive it is therefore possible to realize the functions of disconnection and grounding.
PRIOR ART
In the precharacterizing clause, the invention makes reference to a prior art of switchgear assemblies, as is described in EP 1 249 910 A2 . In a switchgear assembly described in figure 3 of this document and having a horizontally guided double busbar, a first current terminal of a circuit breaker can optionally be connected to a first or a second busbar of the double busbar via a first or a second busbar disconnector, which each have a disconnection and grounding function. A coupling panel or feeder described in figure 4 likewise has a horizontally guided double busbar. Each of the two current terminals of the circuit breaker is in each case passed to one of the two busbars of the double busbar via a busbar disconnector having disconnection and grounding functions and having only one drive. The busbar disconnector has an apparatus for grounding one of the two current terminals of the circuit breaker. In addition, it contains an apparatus for disconnecting one of the two busbars from the current terminal which can be grounded. In the case of all of these assemblies, separate drives for the grounding function and for the busbar disconnection and connection function are replaced by a single drive. Owing to the arrangement of the busbars, however, busbar disconnectors having different designs are required for each phase.

Such switching devices are known, for example, from Hitachi Review Vol. 51 (2002) No. 5 pp. 169 to 173 or from EP 1 068 624 Bl. The switching devices described in these prior publications for gas-insulated, metal-encapsulated switchgear assemblies each have a three-position switch, which can implement all of the functions of a disconnecting and grounding switch using a single drive. In this case, a moveable contact element, which is arranged in an encapsulating housing, is displaced along an axis, which axis is passed through a disconnector contact and through a grounding contact. With a linear movement of the contact element, it is therefore possible for three switching positions of the switching device to be reached. In a first one of these three positions, the contact element is in engagement neither with the disconnector contact nor with the grounding device contact (neutral position), i.e. both an elbow disconnector integrated in the switching device and a grounding device integrated in the switching device are open. In a second position, the contact element engages in the disconnector contact. The disconnection switching point of the disconnector is now closed when the grounding device is open. In the third position, the contact element engages in the grounding contact. The grounding device is now closed when the disconnector is. open.
Driving force for the moveable contact element is transmitted transversely with respect to its movement direction. For this purpose, the encapsulating housing requires additional space transversely with respect to the axis (Hitachi Review), or a specially designed current conductor accommodating a lever transmission is required (EP 1 068 624 Bl) .
DESCRIPTION OF THE INVENTION
The invention, as it is defined in the independent patent claim, achieves the obj ect of specifying a

switchgear assembly of the type mentioned initially which is characterized by a compact design and at the same time by considerable operational convenience.
In the switchgear assembly according to the invention, the combined disconnecting-earthing switches are aligned such that at least two drive apparatuses, which are provided for their actuation, point in the same direction. Sections of, the assembly which are connected to the combined disconnecting-earthing switches are arranged in the opposite direction. For these reasons, the housing of the circuit breaker can be shortened, and the assembly may have a compact and clear design. If the drives are aligned towards a control aisle of the assembly, the positions of the drives and therefore also the switching positions of the combined disconnecting-earthing switches are visually accessible to the operator of the assembly. Good operational reliability and a high degree of operational convenience of the assembly are therefore achieved. These advantageous effects occur even if the assembly is equipped only with a single busbar.
The switchgear assembly can be single-phase-encapsulated or three-phase- or generally polyphase-encapsulated. A common drive apparatus is advantageously provided in each case for three phases. In each case a dedicated drive apparatus may also be provided for each phase. A drive apparatus comprises at least one drive unit, which transmits force to at least one switching device. In particular, the drive apparatus - may comprise a lever system or force transmission elements, which transmit the force from a central drive unit to the number of switching devices which corresponds to the number of phases.
All of the drive apparatuses preferably point in the same direction. The drive apparatuses particularly preferably point in the same, predominantly horizontal

direction. The circuit breaker is typically aligned horizontally. The combined disconnecting-earthing switches are advantageously of identical design. The identical design relates in particular to the shape of the housing or disconnector housing with the associated connection openings or connection flanges, but does not necessarily include an identical configuration of the combined disconnecting-earthing switches in the interior as regards their current-carrying elements and current interruption elements.
If the switchgear assembly contains a cross-coupling panel or feeder, i.e. if it also has a second busbar which is guided predominantly horizontally and a housing of the second combined disconnecting-earthing switch supports a housing of this second busbar, it is advantageous to arrange the disconnector housings and the busbars supported by the disconnector housings such that they are offset with respect to one another in the vertical direction. Whilst maintaining a compact design of the switchgear assembly, it is therefore" also ensured in the cross-coupling feeder that the drives and therefore the switching positions of the combined disconnecting-earthing switches can easily be seen.
If the switchgear assembly according to the invention contains a double busbar, i.e. a third busbar is likewise provided which is guided predominantly horizontally but can be connected to the first current terminal via a third combined disconnecting-earthing switch, a housing of the first combined disconnecting-earthing switch supports a section of the first busbar, and a housing of the third combined disconnecting-earthing. switch supports a section of the third busbar. The first and third combined disconnecting-earthing switches are preferably of identical design. If the two disconnector housings are connected to one another via a module which contains a connection node of the first current terminal, the housings of the first and the

third combined disconnecting-earthing- switches and the busbars supported by these housings should expediently be arranged such that they are offset with respect to one another in the vertical direction. Since the drives do not protrude from the busbars on both sides, the busbars can be joined together irrespective of the dimensions of the housing of the circuit breaker, as a result of which the assembly is extremely compact. Despite this high degree of compactness, it is still ensured that the drives and therefore also the switch positions can easily be seen.
The combined disconnecting-earthing switches are each in the form of elbow disconnectors. At least the first of the two limbs of the elbow is arranged predominantly horizontally and has, in a coaxial arrangement, a grounding contact, a drive guided through the grounding contact and two contacts of a disconnector. The above-described advantages can therefore be achieved ih a particularly economical manner. That is to say only a single switch is then required for the functions of disconnection and grounding. Different switches, such as in particular series disconnectors, are then not required.
If, in the case of the second and the third combined disconnecting-earthing switches, the second limb of the elbow is guided in each case predominantly vertically and, in the case of the first combined disconnecting-earthing switch, predominantly horizontally, the third busbar provided in the assembly with a double busbar can be connected to the third combined disconnecting-earthing switch in a particularly space-saving manner. Then, the first busbar is attached to the second limb of the first combined disconnecting-earthing switch and extends in the direction of this limb, and the third busbar is attached to the first limb of the third combined disconnecting-earthing switch and is aligned perpendicularly with respect to the first limb.

A moveable one of the two disconnector contacts advantageously contains two contact parts, which are connected to a retaining element and of which a first contact part forms the mating contact of a grounding device containing the grounding contact and a second contact part forms the mating contact of a stationary contact of the disconnector. These measures make it possible to form three switching devices having the functions of disconnection and grounding, only disconnection or only grounding using only a single basic switching device.' If the contact parts are connected detachably to the retaining element, retrofitting between the three switching devices takes place by means of opening or closing at most two detachable connections. If the retaining element supports both contact parts, the switching device is in the form of a combined disconnecting and grounding switch (combination disconnector). In this case, it is possible for the functions of disconnection and grounding to be carried out in a gas-insulated,. encapsulated switchgear assembly using one switching device, which has only a single drive. However, this means that the disconnection point and grounding point in the assembly are closely adjacent to one another. If the disconnection point and grounding point are far removed from one another and it is only necessary to perform a grounding task or a disconnection task, only one of the contact tubes needs to be removed once one of the two detachable connections has been opened in order to provide a switching device with a disconnector or grounding device function. The electrical functions of disconnection and grounding, only disconnection or only grounding using a single type of switching device can therefore be covered in gas-insulated, encapsulated switchgear assemblies. The costs associated with the storage and fitting of the assembly are therefore reduced.

The node module, which is provided in the assembly according to the invention with a double busbar and contains the connection node, is advantageously in the form of a T and is installed in the assembly such that the arms of the T are aligned vertically and form a predominantly vertical longitudinal connection, such that the base of the T forms a predominantly horizontal transverse connection, and such that the module of the first combined disconnecting-earthing switch is connected to the node module at the horizontally guided base of the T, and the module of the third combined disconnecting-earthing switch is connected to the node module at the upwardly guided arm of the T. This node module makes it possible to install the first and the third combined disconnecting-earthing switches and improves the visibility of the switch positions and the revisability of the assembly in a simple manner by means of misaligning or offsetting the height of the first and the third combined disconnecting-earthing switches and the two busbars. At the same time, the gas chambers of the first and the third combined disconnecting-earthing switches can be shielded from one another by this encapsulating module, with the result that the revisability of the assembly is additionally improved. The housing of the node module may be in the form of a T or in the form of an X; but, irrespective of this, the connection node formed by current conductors is in the form of a T.
If the assembly according to the invention has two or more encapsulated phases, which in particular are single-phase- or polyphase-encapsulated, it is recommended for the combined disconnecting-earthing switches and further switching devices which may be provided and which only act as disconnectors or only as grounding devices to be of identical design and/or to be aligned in identical fashion in all phases. The production costs and maintenance costs of the assembly according to the invention can then be significantly

reduced. This can be achieved, whilst at the same time saving on space, in a particularly advantageous manner by switching devices which are arranged in different phases but perform identical functions being arranged on a diagonal determined by the vertical and horizontal direction or spacing. Correspondingly, lever systems can be arranged on this diagonal which transmit force from a central drive unit to the number of switching devices which number . corresponds to the number of phases.
Further embodiments, advantages and applications cf the
invention result from the dependent claims, the
combinations of claims and from the description now
following and the figures.
DESCRIPTION OF THE DRAWINGS
The invention will be explained below with reference to exemplary embodiments. In the drawings:
figure 1 shows a side view of a three-phase,
single-phase-encapsulated switchgear assembly according to the prior art with a double busbar,
figure 2 shows a circuit diagram representing only one phase of the assembly shown in figure 1,
figure 3 shows a side view of a switchgear assembly
according to the invention performing the same functions as the assembly of figure 1,
figure 4 shows a side view of an embodiment of the
switchgear assembly according to the invention having a single busbar,
figure 5 shows a side view of a section of an
embodiment of the switchgear assembly according to the invention in the form of a cross-coupling panel or feeder,

figure 6 shows a cross-sectional illustration through a combined disconnecting-earthing switch 71 used in the switchgear assembly of figure 3, and
figures 7, 8 show GIS configurations with a double . busbar, in a side view, for a three-phase-encapsulated switchgear assembly according to the invention.
In all of the figures, the same references also denote functionally identical parts.
APPROACHES TO IMPLEMENTING THE INVENTION
The switchgear assembly having a three-phase design illustrated in figure 1 and in accordance with the prior art is single-phase-encapsulated and has a separate metal encapsulation filled with insula ;^r:g gas for each of its three phases. Each encapsulation is of modular design and has the circuit diagram shown in figure 2, in which a circuit breaker having two current terminals 11, 12 is denoted by the reference 10. As can be seen, the current terminal 11 is connected Lo a connection node 13 monitored by a current transformer
21, and the current terminal 12 is connected to a
connection node 14 monitored by a voltage transformer
22. In addition, two busbar disconnectors 31, 32 and a
grounding device 41 are connected to the connection
node 13, and a disconnector 33 and a grounding device
42 are connected to the connection node 14. Those
terminals of the busbar disconnectors 31, 32 which are
remote from the connection node 13 are in each case
connected to one of two horizontally guided busbars 51,
52, whereas that terminal of the disconnector 3 3 which
is remote from the connection node 14 is connected to a
grounding device 43 and an outgoing feeder 6 0 or a
further busbar.

It can be seen from the topology of the assembly given in figure 1 that the circuit breaker 10 is in the form of a horizontally arranged encapsulating module and has a switch housing having two flange attachments representing the current terminals 11 and 12. A vertically guided encapsulating module containing the current transformer 21 is fixed to the flange attachment associated with the current terminal 11. This current transformer module 21 supports a T-shaped module accommodating the connection node 13. In each case one module containing the disconnector 31 or 32, respectively, is attached to each of the two arms of the T of this node module 13. The two disconnector modules 31 and 32 and the busbars 51 and 52 connected to the disconnectors are therefore arranged at the same height. The grounding device 41 is arranged at the upper end of the node module 13. A vertically guided module containing the voltage transformer 22 is fixed to the flange attachment associated with the current terminal 12. This voltage . transformer module 22 supports, in an arrangement in the form of a column, an intermediate module (with no designation) and an L-shaped module accommodating the connection node 14. A horizontally guided encapsulating module of the disconnector 33 is fixed to a horizontally aligned flange attachment of the node module 14. The grounding switch 4 2, which serves the purpose of grounding the connection node 14, is arranged at the switch-side end of the disconnector module 33, and the grounding device 43, which serves the purpose of grounding the outgoing feeder 60, is arranged at the outgoing-feeder-side end of the disconnector module 33.
In the switchgear assembly according to the invention illustrated in figure 3, the same circuitry is realized; as in the switchgear assembly shown in figure 1, but it has a different topology. This is firstly determined by the fact that, in place of the three disconnectors 31, 32 and 33 and two grounding devices 41 and 42 with in

total five drives, only three switching devices having a disconnection and grounding function (combined disconnecting-earthing switches 71, 72, 73) are used which in each case only require a single drive 81, 82, 83 for carrying out the two functions. Secondly, this different topology is also brought about by the fact that the combined disconnecting-earthing switches 71, 72, 73 are aligned such that the three drives 81, 82, 83, which are provided for their actuation, point in the same, in this case predominantly horizontal direction. Furthermore, the disconnector modules 71, 72 and the busbars 51 and 52 supported by them are also arranged such that they are offset with respect to one another in the vertical direction.
*
Owing to the use of the combined disconnecting-earthing switches, the number of drives is reduced from five to three. In place of various types of switches, such as disconnectors and grounding devices, the combined disconnecting-earthing switch is now only used as a single switching device for performing disconnection and grounding tasks. Correspondingly, only a single drive type is now required, this type having a central drive head 85 and a connecting lever system 85 for the drive between the phases, These parts clearly correspond to the corresponding parts of the drive 82. In order to allow for a compact arrangement, the busbars 51 or 52 of different phases are arranged vertically one above the other, as can be seen. The combined disconnecting-earthing switches, for example 71 or 72, which are provided in the three phases but perform identical functions, are arranged on a diagonal determined by the vertical and horizontal direction or spacing and are connected to one another by means of the lever system 86 guided along this diagonal. As can be seen, in all three phases the combined disconnecting-earthing switches 71, 72, 73 are advantageously of identical design and/or are aligned in identical fashion. This also applies to further

switching devices which may be provided and which are only in the form of disconnectors or only in the form of grounding devices.
The uniform alignment of the combined disconnecting-earthing switches 71, 72, 73 in the predominantly horizontal direction makes it possible for all of the drives 81, 82, 83 and therefore also their position indicators to be oriented towards a control aisle of the assembly. From the control aisle, the assembly can therefore be monitored and maintained much more easily. This can also be seen in figure 3. Since the drives of the combined disconnecting-earthing switches 71 and 72 are aligned towards one side and do not protrude on both sides of the busbars 51 and 52 as do the drives of the disconnectors 31 and 32, space is also saved. The advantages according to the invention are even achieved when at least two individual drives of combined disconnecting-earthing switches installed at different locations point in the same, typically horizontal direction.
It can also be seen from figure 3 that the visibility of the drives and the position indicators associated with them is also further improved if the combined disconnecting-earthing switches 71, 72, 73 and the busbars 51 and 52 supported by the combined disconnecting-earthing switches 71 and 72 are arranged such that they are offset with respect to one another in the vertical direction.
In contrast to the previously explained embodiments with the double busbar, the switchgear assembly illustrated in figure 4 has only the horizontally guided busbar 51, which is supported by the housing of the combined disconnecting-earthing switch 71. As a result of the fact that the drives of the combined disconniecting-earthing switches, namely the drive 81 of the combined disconnecting-earthing switch 71 provided

on the busbar side and the drive 83 of the combined disconnecting-earthing switch 73 provided on the outgoing-feeder side, are guided in the horizontal direction and point in the same direction, the operational convenience and accessibility are considerably improved even in the case of this switchgear assembly with a single busbar.
Even in the case . of the cross-coupling feeder illustrated in figure 5 of one embodiment of the switchgear assembly according to the invention, the operational convenience and, accessibility are excellent. As a result of the fact that the two busbars 51 and 53 and, in a corresponding manner, also the two combined disconnecting-earthing switches 71 and 73 are arranged such that they are offset vertically with respect to one another, the drives 81 and 83 can be seen particularly easily and are particularly easily accessible. Owing to the alignment of the drives 81 and 83 in one direction, at the same time space is saved. At the same time, in this case the number of switching devices required having a disconnector and/or grounding device function is halved.
Figure 6 illustrates the combined disconnecting-earthing switch 71, as it is When installed in the switchgear assembly shown in figures 3-5 or else figures 7-8. Reference will be, made to the European priority application which is hereby incorporated/ with its entire disclosure content, in the description. The combined disconnecting-earthing switch 71 or else 72 and 73 has a metal housing 1 which is filled with insulating gas and has three openings 2, 3 and 4, which are each delimited by a flange (with no designation). The flanges in each case serve the purpose of making the connection with a mating flange (not illustrated) of the adjacent module of the switchgear assembly. The openings 2 to 4 are in each case sealed in a gas-tight manner by a barrier insulator (with no designation),

which, in a manner which is electrically insulated from the housing 1, supports in each case one current conductor 5, 6 and 7 which can have a high voltage applied to it.
A predominantly horizontal axis a, which determines the movement direction of a contact element 9 of the switching device which can be displaced by a threaded spindle 8! and a spindle nut 8' and along which the current conductor 6 is guided from the outside into the interior of the housing 1, passes centrally through the opening 3. The openings 2 and 4 are opposite one another in the housing 1 such that the current conductors 5 and 7 are aligned along a line.b which is passed centrally through the openings. The axis a and the line b enclose a right angle with one another and therefore determine the geometry of a current path containing the current conductors 5 and 6. In addition to the conductor 6 and the moveable contact element 9, a grounding contact 2 0 and a disconnector contact 3 0, which is connected to the current conductor 6, are also arranged on the axis.
The current conductor 5 is connected to a section of the busbar 51 which is guided to the right, the current conductor 7 is connected to a section of the busbar 51 which is guided to the left, and the current conductor 6 is connected to the connection node 13. As can be seen, the combined disconnecting-earthing switch 71 is in the form of an elbow disconnector, and the two limbs of the elbow are arranged predominantly horizontally in the assembly. The moveable contact 9 has two contact parts 91, 9'!, which are connected, in particular detachably connected or fixedly connected, to one of the retaining elements (with no designation) or is even integral with said retaining element, and of which a first contact part 9' forms the mating contact o*. a grounding device E containing the grounding contact 2 0 and a second contact part 9' ' forms the mating contact

of a stationary contact of a disconnector T. By-removing one of the parts 9' or 9' ' , it is thus possible for a switching device only having a grounding device function E or only having a disconnector function T to be formed from the , combined disconnecting-earthing switch, which switching device may be installed in the assembly corresponding to the combined disconnecting-earthing switches 71 to 73.
The switch 71 is installed horizontally. The limbs of the elbow, namely the axis a and the busbar 51, which is guided as a longitudinal connection through the switch, extend horizontally. On the other hand, the switches 72 and 73 are installed vertically since only the axis a is guided horizontally, but the line b is guided vertically downwards.
The node module containing the connection node 13 is in the form of a T and is installed in the assembly such that the arms of the T are guided vertically and form a predominantly vertical longitudinal connection. The base of the T forms a predominantly horizontal transverse connection. If the module of the combined disconnecting-earthing switch 72 is now connected to the node module 13 at the upwardly guided arm of the T, and the module of the combined disconnecting-earthing switch 71 is connected to the node module 13 at the horizontally guided base of the T, the horizontal alignment of the drive axes a of the combined disconnecting-earthing switches 71 and 72 and, at the same time, the vertical displacement of the disconnectors is achieved directly, as a result. The housing of the node module 13 may be in the form of a T or in the form of an X, but, irrespective of this, the connection node formed by current conductors is in the -form of a T. If the housing of the node module is in the form of an X, one of the four openings of the X can be closed by a cover or a rupture disk, but may

advantageously also be used for passing through a sensor.
Figure 7 and figure 8 show two exemplary embodiments similar to that in figure 3 with a double busbar in the case of a three-phase-encapsulated switchgear assembly. In figure 7, the drive apparatuses 81, 82 both of the first and the third combined disconnecting-earthing switches 71, 72 and the second combined disconnecting-earthing switch 73, which is arranged at the outgoing feeder, are oriented in the same direction. In other words, the busbar disconnectors 71, 72 and the outgoing-feeder disconnector 73 are oriented'or aligned in identical fashion. In particular, the busbar disconnectors 71, 72 and the outgoing-feeder disconnector 73 have identical housings 1, in particular as described in figure 6, and are installed in the same orientation. In figure 8, the busbar disconnectors 71, 72 or their drive apparatuses 81, 82 are aligned in identical fashion, but in the opposite direction to the outgoing-feeder disconnector 73. The operational convenience, in particular the possibility to read and monitor at the same time, is in this case achieved for the busbar disconnectors 71, 72 alone. In any case, a very compact design is achieved for a gas-insulated switchgear assembly.

LIST OF REFERENCES
1 Encapsulating housing
2,3,4 Openings
5,6,7 Current conductors
8' Threaded spindle
8 f ' Spindle nut
9 Contact element 9',9' Contact parts
10 Circuit breaker 11,12 Current terminals
13,14 Connection node, node module
2 0 Grounding contact
21 Current transformer
22 Voltage transformer
30 Disconnector contact
31,32,33 Disconnectors
41,42,43 Grounding devices
51,52,53 Busbars
60 Outgoing feeder
71,72,73 Combined disconnecting-earthing switches
81,82,83 Drives
85 Drive head, central drive head
a Axis
b Line
E Grounding device
T Disconnector







CLAIMS
1. A promoter for ATP release from erythrocytes, comprising a substance which stabilizes the structure of hemoglobin in erythrocytes in the T-state.
2. The promoter according to claim 1, wherein the substance which stabilizes the structure of hemoglobin in erythrocytes in the T-state is at least one selected from the group consisting of bezafibrate, nitric oxide, carbon dioxide and adenosine.
3. The promoter according to claim 1 or 2, which is capable of releasing ATP extracellularly under an oxygen partial pressure of 100 mmHg or less.
4. A pharmaceutical composition comprising a substance which stabilizes the structure of hemoglobin in erythrocytes in the T-state.
5. The pharmaceutical composition according to claim 4, wherein the substance which stabilizes the structure of hemoglobin in erythrocytes in the T-state is at least one selected from the group consisting of bezafibrate, nitric oxide, carbon dioxide and adenosine.
6. The pharmaceutical composition according to claim 4 or 5, which is capable of releasing ATP extracellularly under an oxygen partial pressure of 100 mmHg or less.
7. The pharmaceutical composition according to any one of claims 4 to 6, which is a vasodilator or a blood flow improver.
8. A method of releasing ATP from erythrocytes, comprising stabilizing the structure of hemoglobin in the erythrocytes in the T-state.
9. The method according to claim 8, wherein ATP is released under an oxygen partial pressure of 100 mmHg or less.

10. An inhibitor against ATP release from erythrocytes, comprising a substance which stabilizes the structure of hemoglobin in erythrocytes in the R-state.
11. The inhibitor according to claim 10, wherein the substance which stabilizes the structure

of hemoglobin in erythrocytes in the R-state is carbon monoxide or sulfonylurea.
12. The inhibitor according to claim 10 or 11, which is capable of inhibiting ATP release under an oxygen partial pressure of 100 mmHg or less.
13. A pharmaceutical composition comprising a substance which stabilizes the structure of hemoglobin in erythrocytes in the R-state.
14. The pharmaceutical composition according to claim 13, wherein the substance which stabilizes the structure of hemoglobin in erythrocytes in the R-state is carbon monoxide or sulfonylurea.
15. The pharmaceutical composition according to claim 13 or 14, which is capable of inhibiting ATP release under an oxygen partial pressure of 100 mmHg or less.
16. The pharmaceutical composition according to any one of claims 13 to 15, which is a vasoconstrictor or a blood flow regulator.
17. A method of inhibiting ATP release from erythrocytes, comprising stabilizing the structure of hemoglobin in the erythrocytes in the R-state.
18. The method of claim 17, wherein ATP release is inhibited under an oxygen partial pressure of 100 mmHg or less.
19. Erythrocytes in which the structure of hemoglobin is stabilized in the T-state.
20. The erythrocytes according to claim 19, which have been treated with at least one substance selected from the group consisting of bezafibrate, nitric oxide, carbon dioxide, adenosine and hydrogen ion.
21. The erythrocytes according to claim 19 or 20, which are capable of releasing ATP under an oxygen partial pressure of 100 mmHg or less.
22. Erythrocytes in which the structure of hemoglobin is stabilized in the R-state.

23. The erythrocytes according to claim 22, which have been treated with carbon monoxide or sulfonylurea.
24. The erythrocytes according to claim 22 or 23, which are capable of inhibiting ATP release under an oxygen partial pressure of 100 mmHg or less.
25. A pharmaceutical composition comprising the erythrocytes according to any one of claims 19 to 21.
26. The pharmaceutical composition according to claim 25, which is for treating ischemic diseases.
27. The pharmaceutical composition according to claim 26, wherein the ischemic disease is at least one selected from the group consisting of hemorrhagic shock, myocardial infarction, angina pectoris, cerebral infarction, intracerebral hemorrhage, obliterative arterial diseases, vascular disorders caused by diabetes, coronary artery stenosis, ischemic diseases of extremities, arteriosclerosis obliterans and ischemic ulcer/necrosis.
28. The pharmaceutical composition according to claim 26, wherein the ischemic disease is ischemia-reperfusion syndrome.
29. The pharmaceutical composition according to claim 28, wherein the ischemia-reperfusion syndrome results from at least one cause selected from the group consisting of post-shock resuscitation, perfusion after cold storage of organs, recanalization of blood flow after surgical operations, and reconstruction of obliterated blood vessels.
30. The pharmaceutical composition according to claim 25, which is for treating acidosis.
31. A pharmaceutical composition comprising the erythrocytes according to any one of claims 22 to 24.
32. The pharmaceutical composition according to claim 31, which is for treating vasodilatory diseases.
33. The pharmaceutical composition according to claim 32, wherein the vasodilatory disease

is septic shock or anaphylactic shock.
34. A method of measuring ATP, comprising quantitatively determining the amount of ATP
released from erythrocytes in an oxygen concentration-dependent manner.
35. A method of enhancing ATP release from erythrocytes, comprising adding adenosine to
an erythrocyte suspension and exposing the resultant suspension to a no oxygen or low oxygen
partial pressure condition.
36. The method according to claim 35, wherein the no oxygen or low oxygen partial pressure condition is a condition where oxygen partial pressure is 0-150 mmHg.
37. A method of enhancing ATP release from erythrocytes, comprising adding adenosine to an erythrocyte suspension and exposing the resultant suspension to a carbon dioxide partial pressure of 60-80 mmHg.
38. The method according to any one of claims 35 to 37, wherein the concentration of
adenosine is 0.1-10 jjmol/L.
39. A method of controlling ATP release from erythrocytes, comprising adding a substance
that inhibits the anion permeation function of band 3 protein to an adenosine-added erythrocyte
suspension.
40. The method of claim 39, wherein the substance that inhibits the anion permeation function of band 3 protein is sulfonylurea.
41. A controller for ATP release from erythrocytes, comprising a substance that inhibits the anion permeation function of band 3 protein.
42. The controller according to claim 41, wherein the substance that inhibits the anion
permeation junction of band 3 protein is sulfonylurea.
43. The controller according to claim 41 or 42, which is for inhibiting ATP release.
Dated this 28 day of August 2006

Documents:

3116-CHENP-2006 AMENDED CLAIMS 08-11-2011.pdf

3116-CHENP-2006 CORRESPONDENCE OTHERS 16-01-2012.pdf

3116-CHENP-2006 EXAMINATION REPORT REPLY RECEIVED 08-11-2011.pdf

3116-CHENP-2006 FORM-3 08-11-2011.pdf

3116-CHENP-2006 FORM-3 16-01-2012.pdf

3116-CHENP-2006 OTHER PATENT DOCUMENT 08-11-2011.pdf

3116-CHENP-2006 POWER OF ATTORNEY 08-11-2011.pdf

3116-CHENP-2006 CLAIMS.pdf

3116-CHENP-2006 CORREPONDENCE OTHERS.pdf

3116-CHENP-2006 CORREPONDENCE PO.pdf

3116-CHENP-2006 CORRESPONDENCE OTHERS 01-03-2011.pdf

3116-CHENP-2006 FORM-18.pdf

3116-chenp-2006-abstract.pdf

3116-chenp-2006-claims.pdf

3116-chenp-2006-correspondnece-others.pdf

3116-chenp-2006-description(complete).pdf

3116-chenp-2006-drawings.pdf

3116-chenp-2006-form 1.pdf

3116-chenp-2006-form 3.pdf

3116-chenp-2006-form 5.pdf

3116-chenp-2006-pct.pdf


Patent Number 250712
Indian Patent Application Number 3116/CHENP/2006
PG Journal Number 04/2012
Publication Date 27-Jan-2012
Grant Date 20-Jan-2012
Date of Filing 28-Aug-2006
Name of Patentee ABB TECHNOLOGY AG
Applicant Address Affolternstrasse 44, CH-8050 Zurich
Inventors:
# Inventor's Name Inventor's Address
1 HOLAUS, Walter Okenstrasse 7, CH-8037 Zurich
2 SOLOGUREN-SANCHEZ, Diego Lindenhof 14, CH-5430 Wettingen
3 MUELLER, Lorenz Rebbergstrasse 17, CH-5412 Gebenstorf
4 BRUCKERT, Michael Bahnhofstrasse 5, CH-8153 Rumlang
PCT International Classification Number H02B13/035
PCT International Application Number PCT/CH2005/000114
PCT International Filing date 2005-02-28
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 04405114.2 2004-02-27 EUROPEAN UNION