| Title of Invention | SUBSTITUTED PYRROLIDINONES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 |
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| Abstract | The present invention discloses novel compounds of Formula I: ( I ) possessing 11β -HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, cognitive disorders, and other conditions associated with 11 β -HSD type 1 activity. |
| Full Text | PLEASE SEE THE SPECIFICATION ATTACHED. |
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2107-MUMNP-2008-PCT-IB-373(1-12-2008).pdf
2107-MUMNP-2008-PCT-ISA-237(1-12-2008).pdf
2107-MUMNP-2008-PCT-OTHER(1-12-2008).pdf
2107-MUMNP-2008-REPLY TO EXAMINATION REPORT(13-5-2011).pdf
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| Patent Number | 250583 | ||||||||||||||||||
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| Indian Patent Application Number | 2107/MUMNP/2008 | ||||||||||||||||||
| PG Journal Number | 02/2012 | ||||||||||||||||||
| Publication Date | 13-Jan-2012 | ||||||||||||||||||
| Grant Date | 11-Jan-2012 | ||||||||||||||||||
| Date of Filing | 01-Oct-2008 | ||||||||||||||||||
| Name of Patentee | ELI LILLY AND COMPANY | ||||||||||||||||||
| Applicant Address | LILLY CORPORATE CENTER, CITY OF INDIANAPOLIS, STATE OF INDIANA 46285. | ||||||||||||||||||
Inventors:
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| PCT International Classification Number | C07D207/27 | ||||||||||||||||||
| PCT International Application Number | PCT/US2007/067200 | ||||||||||||||||||
| PCT International Filing date | 2007-04-23 | ||||||||||||||||||
PCT Conventions:
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