Title of Invention

A COMPOUND OF FORMULA (I)

Abstract The invention relates to novel processes for the preparation of para-nitrobenzyl esters and allyl esters useful in the preparation of 3-cyclic-ether-substituted cephalosporins. The invention also relates to novel processes for preparing the above para-nitrobenzyl esters and allyl esters by the use of trimethylphosphine. The invention also relates to 3-cyclic-ether-substituted cephalosporins.These compounds possess certain advantageous properties, such as crystalline form and high enantiomeric excess (e.e.). The 3-cyclic-ether-substituted cephalosporins prepared by the methods of the present invention have prolonged and high levels of antibacterial activity and possess good absorption parentally in humans and animals. The 3-cyclic-ether-substituted cephalosporins prepared by the processes of the present invention contain a cyclic ether substituent at the 3-position of the cephalosporin nucleus.
Full Text

Documents:

686-mumnp-2004-abstract(12-7-2006).pdf

686-MUMNP-2004-ABSTRACT(GRANTED)-(29-6-2011).pdf

686-mumnp-2004-affidavit(22-9-2006).pdf

686-mumnp-2004-cancelled pages(12-7-2006).pdf

686-mumnp-2004-claims(24-11-2004).pdf

686-mumnp-2004-claims(amended)-(12-7-2006).pdf

686-MUMNP-2004-CLAIMS(GRANTED)-(29-6-2011).pdf

686-mumnp-2004-correspondence(17-4-2008).pdf

686-MUMNP-2004-CORRESPONDENCE(IPO)-(29-6-2011).pdf

686-mumnp-2004-correspondence(ipo)-(5-3-2008).pdf

686-mumnp-2004-description(complete)-(24-11-2004).pdf

686-MUMNP-2004-DESCRIPTION(GRANTED)-(29-6-2011).pdf

686-mumnp-2004-form 1(12-7-2006).pdf

686-mumnp-2004-form 1(22-9-2006).pdf

686-mumnp-2004-form 1(24-11-2004).pdf

686-mumnp-2004-form 13(22-9-2006).pdf

686-mumnp-2004-form 18(5-10-2005).pdf

686-mumnp-2004-form 2(24-11-2004).pdf

686-MUMNP-2004-FORM 2(GRANTED)-(29-6-2011).pdf

686-mumnp-2004-form 2(title page)-(24-11-2004).pdf

686-MUMNP-2004-FORM 2(TITLE PAGE)-(GRANTED)-(29-6-2011).pdf

686-mumnp-2004-form 3(12-7-2006).pdf

686-mumnp-2004-form 3(24-11-2004).pdf

686-mumnp-2004-form 5(22-9-2006).pdf

686-mumnp-2004-form 5(24-11-2004).pdf

686-mumnp-2004-general power of attorney(24-11-2004).pdf

686-mumnp-2004-marked copy(12-7-2006).pdf

686-mumnp-2004-petition under rule 137(12-7-2006).pdf

686-mumnp-2004-power of authority(12-7-2006).pdf

686-mumnp-2004-specification(amended)-(12-7-2006).pdf

686-MUMNP-2004-WO INTERNATIONAL PUBLICATION REPORT(24-11-2004).pdf


Patent Number 248242
Indian Patent Application Number 686/MUMNP/2004
PG Journal Number 26/2011
Publication Date 01-Jul-2011
Grant Date 29-Jun-2011
Date of Filing 24-Nov-2004
Name of Patentee PFIZER PRODUCTS, INC.
Applicant Address EASTERN POINT ROAD, GROTON, CONNECTICUT 06340.
Inventors:
# Inventor's Name Inventor's Address
1 JOHN LLOYD TUCKER PFIZER GLOBAL RESEARCH AND DEVELOPMENT, EASTERN POINT ROAD, GROTON, CONNECTICUT 06340.
2 JUAN CARLOS COLBREG PFIZER GLOBAL RESEARCH AND DEVELOPMENT, EASTERN POINT ROAD, GROTON, CONNECTICUT 06340.
3 MAURIZIO ZENONI ACS DOBFAR S.P.A., VIALE ADDETTA 6/8/10, 20067 TRIBIANO, MILANO.
4 GIOVANNI FOGLIATO ACS DOBFAR S.P.A., VIALE ADDETTA 6/8/10, 20067 TRIBIANO, MILANO.
5 ALESSANDRO DONADELLI ACS DOBFAR S.P.A., VIALE ADDETTA 6/8/10, 20067 TRIBIANO, MILANO.
6 HIROMASA MORITA OF AICHI 487-0003.
7 HIDEYUKI MATSUO OF NISHIMATSUURA-GUN, SAGA 844-0012.
8 ISAO NAGAKURA OF TOCHIGI 326-0824.
PCT International Classification Number C07D,501/08
PCT International Application Number PCT/IB01/02181
PCT International Filing date 2001-11-19
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 60/251,018 2000-12-04 U.S.A.