Title of Invention

AN IMPROVED PROCESS FOR PREPARATON OF 5,6-DIHYDRO-4H-4(S)- ETHYLAMINO-6(S)- METHYLTHIENO [2,3-B] THIOPYRAN-2-SUFONAMIDE-7,7-DIOXIDE

Abstract The present invention relates to resolution of (cis,trans) 5,6 -dihydro -4H-4-ethylamino-6-methylthieno[2,3-b] thiopyran-2-sulfonamide-7,7 -dioxide using dibenzoyl-L-tartaric acid monohydrate or di-p-toluoyl-L-tartaric acid monohydrate as a chiral resolving agent in presence of methanol to obtain hemitartarate salt of 5,6-dihydro-4H-4(S)-ethylamino-6(S) methylthieno [2,3-b] thiopyran-2-sulfonamide -7,7 -dioxide with de of > 95% followed by purification using methanol to obtain hemitartarate salt with de of >99%, Chemical purity >99.5% with cis isomer content of <0.1% and further converting into its pharmaceutically acceptable salts, preferably hydrochloride salt.
Full Text

Documents:

741-MUM-2004-ABSTRACT(6-7-2005).pdf

741-MUM-2004-ABSTRACT(9-7-2004).pdf

741-MUM-2004-ABSTRACT(GRANTED)-(14-6-2011).pdf

741-MUM-2004-CANCELLED PAGES(7-2-2011).pdf

741-MUM-2004-CLAIMS(6-7-2005).pdf

741-MUM-2004-CLAIMS(AMENDED)-(7-2-2011).pdf

741-MUM-2004-CLAIMS(GRANTED)-(14-6-2011).pdf

741-MUM-2004-CLAIMS(MARKED COPY)-(7-2-2011).pdf

741-MUM-2004-CORRESPONDENCE 30-6-2008.pdf

741-MUM-2004-CORRESPONDENCE(1-11-2010).pdf

741-MUM-2004-CORRESPONDENCE(10-12-2008).pdf

741-MUM-2004-CORRESPONDENCE(27-6-2008).pdf

741-MUM-2004-CORRESPONDENCE(7-2-2011).pdf

741-MUM-2004-CORRESPONDENCE(IPO)-(23-6-2011).pdf

741-MUM-2004-DESCRIPTION(COMPLETE)-(6-7-2005).pdf

741-MUM-2004-DESCRIPTION(GRANTED)-(14-6-2011).pdf

741-MUM-2004-DESCRIPTION(PROVISIONAL)-(9-7-2004).pdf

741-MUM-2004-FORM 1(23-8-2004).pdf

741-MUM-2004-FORM 1(23-9-2005).pdf

741-MUM-2004-FORM 1(6-7-2005).pdf

741-MUM-2004-FORM 1(7-2-2011).pdf

741-MUM-2004-FORM 1(9-7-2004).pdf

741-mum-2004-form 13(7-2-2011).pdf

741-MUM-2004-FORM 18 30-6-2008.pdf

741-MUM-2004-FORM 2(COMPLETE)-(6-7-2005).pdf

741-MUM-2004-FORM 2(GRANTED)-(14-6-2011).pdf

741-MUM-2004-FORM 2(PROVISIONAL)-(9-7-2004).pdf

741-MUM-2004-FORM 2(TITLE PAGE)-(7-2-2011).pdf

741-MUM-2004-FORM 2(TITLE PAGE)-(AMENDED)-(7-2-2011).pdf

741-MUM-2004-FORM 2(TITLE PAGE)-(COMPLETE)-(6-7-2005).pdf

741-MUM-2004-FORM 2(TITLE PAGE)-(GRANTED)-(14-6-2011).pdf

741-MUM-2004-FORM 2(TITLE PAGE)-(PROVISIONAL)-(9-7-2004).pdf

741-MUM-2004-FORM 26(23-9-2005).pdf

741-MUM-2004-FORM 26(7-2-2011).pdf

741-MUM-2004-FORM 3(1-11-2010).pdf

741-MUM-2004-FORM 3(23-8-2004).pdf

741-MUM-2004-FORM 3(6-7-2005).pdf

741-MUM-2004-FORM 3(7-2-2011).pdf

741-MUM-2004-FORM 3(9-7-2004).pdf

741-MUM-2004-FORM 5(23-8-2004).pdf

741-MUM-2004-FORM 5(7-2-2011).pdf

741-MUM-2004-FORM 5(9-7-2004).pdf

741-MUM-2004-FORM PCT-IPEA-409(7-2-2011).pdf

741-MUM-2004-OTHER DOCUMENT(7-2-2011).pdf

741-MUM-2004-REPLY TO EXAMINATION REPORT(7-2-2011).pdf


Patent Number 248069
Indian Patent Application Number 741/MUM/2004
PG Journal Number 24/2011
Publication Date 17-Jun-2011
Grant Date 14-Jun-2011
Date of Filing 09-Jul-2004
Name of Patentee FDC LIMITED
Applicant Address 142-148, S.V.ROAD, JOGESHWARI(WEST), MUMBAI 400 102, MHARASHTRA, INDIA
Inventors:
# Inventor's Name Inventor's Address
1 CHANDAVARKAR ANAND MOHAN FDC LIMITED, B-8 MIDC INDUSTRIAL ESTATE, WALUJ-431 136,
2 BAPAT RAJARAM UDAY FDC LIMITED, B-8 MIDC INDUSTRIAL ESTATE, WALUJ-431 136,
3 BADE ANAND ATUL FDC LIMITED, B-8 MIDC INDUSTRIAL ESTATE, WALUJ-431 136,
4 CHAVAN ANAND PANDURANG FDC LIMITED, B-8 MIDC INDUSTRIAL ESTATE, WALUJ-431 136,
PCT International Classification Number C07D 495/04, C07D 495/00, C07D 495/06
PCT International Application Number N/A
PCT International Filing date
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 NA