Title of Invention

FLASK FOR PREPARING A FIXER-BASED CYTOLOGICAL SUSPENSION

Abstract The invention concerns a flask for preparing a fixer-based cytological suspension, equipped with filtering means (4) at least partly immersed in the suspension, characterized in that the filtering means (4) are in the form of a basket-forming filtering material web, whereof the periphery (5) is fixed on the flask and whereof the center (6) is connected to a tube (7), extending towards the opening (2) of the flask, associated with position-maintaining means (8) in the flask and adapted to allow through a pipette for drawing the suspension.
Full Text

The present invention relates to a flask for preparing a fixer-based cytological suspension.
Flasks of this type are used in the state of the art for preparing cytological suspensions, particularly cervical or vaginal cytological suspensions, for analysis, etc...
Samples, particularly cervical or vaginal samples, are taken by practitioners with the aid of special brushes which are fixed, for example releasably, to manipulating handles.
Once the sample has been taken, the practitioner plunges the brush into the flask and detaches it from the handle so as to allow the sampled cells to be deposited in the fixer.
However, undesirable components may also be deposited in the fixer such as, for example, debris picked up by the brush during the sampling (mucous, aggregations, etc.), or skin scales from the practitioner that are deposited in the flask, particularly during handling of the brush in order to detach it from the handle, etc
These components may be very inconvenient during subsequent analysis of the suspension.
The Applicant has already proposed a particular flask structure to try to solve these problems.
That flask is described in the document FR-A-2 792 331.
According to that document, the flask has an opening for receiving a cytological sampling brush fixed releasably to a manipulating handle and is characterized in that the opening

of the flask comprises abutment means for the brush, enabling the brush to be trapped in the flask and detached from the handle, and at least one portion of perforated web for filtering the suspension during a pouring operation.
However, in use, a flask of this type has also shown some disadvantages particularly with regard to clogging of the portion of perforated suspension-filtering web by the above-mentioned components.
The object of the invention is therefore further to improve these preparation flasks.
For this purpose, the subject of the invention is a flask for preparing a fixer-based cytological suspension, equipped with filtering means at least partially immersed in the suspension, characterized in that the filtering means are in the form of a web of filtering material forming a strainer, whereof the periphery is fixed to the flask and whereof the centre is connected to a tube that extends towards the opening of the flask, is associated with means for holding it in position in the flask, and is adapted to allow through a pipette for extracting the suspension.
According to further characteristics of the invention:
- the upper part of the flask is adapted to receive a cover,
- the cover and the corresponding part of the flask comprise complementary screwing means,
- the cover comprises, facing the corresponding end of the tube, at least one piercable and self-sealing portion through

which the extraction pipette can pass and which is adapted to come to bear against that end of the tube in order to ensure leaktightness between the tube and the remainder of the flask,
- the lower part of the flask comprises means forming a decantation cone,
- the means for holding the tube in the flask comprise position-maintaining arms extending between the flask and the tube,
- one of the arms comprises abutment means for enabling a sampling brush to be detached from a manipulating handle in order for the brush to fall into the strainer, and
- one of the arms comprises barbs for combing a sampling brush in order to cause the elements sampled thereby to fall into the strainer.
The invention will be understood further from a reading of the following description which is given purely by way of example with reference to the appended drawings in which:
Figure 1 is a sectioned, schematic side view of a preparation flask according to the invention,
Figure 2 is a partial schematic view of such a flask from above, and
Figure 3 is a partial, sectioned, schematic side view of a portion of a preparation flask according to the invention.

An embodiment of the flask according to the invention is in fact illustrated in Figures 1 and 2.
The flask is a flask for preparing a fixer-based cytological suspension.
The flask is generally indicated 1 and comprises an opening, generally indicated 2, through which a cytological sampling brush can pass.
The flask is equipped with filtering means at least partially immersed in the suspension.,
The filtering means are generally indicated 3 in this drawing and, according to the invention, take the form of a web of filtering material forming a strainer, generally indicated 4, the periphery 5 of which is fixed to the flask and the centre 6 of which is connected to a tube 7 that extends towards the opening 2 of the flask, is associated with means, generally indicated 8, for holding it in position, for example in a central position, in the flask, and is adapted to allow through a pipette for extracting the suspension.
The upper part of the flask, generally indicated 9 in Figure 1, is adapted to receive a cover, generally indicated 10.
Fixing means such as, for example, complementary screwing means, may be provided between this upper part 9 of the flask and the cover 10.
For this purpose, the upper part of the flask is threaded whereas the corresponding part of the cover 10 is tapped, enabling the cover to be screwed onto the corresponding end

of the flask.
The open end of the tube 7 is thus protected.
Moreover, the lower part of the flask comprises a decantation cone, generally indicated 11.
The means, generally indicated 8, for holding the tube 7 in position in the flask are shown in greater detail in Figure 2.
In fact, these holding means may comprise position-maintaining arms extending between the flask 1 and the tube
7. ■
In the embodiment illustrated, three position-maintaining arms are shown, arranged substantially 120 ° apart.
Naturally other configurations may be provided.
One of the arms such as, for example, the arm 12, may be provided with abutment means for enabling a sampling brush to be detached in conventional manner from a manipulating handle thereof in order for the brush to fall into the strainer-forming web of filtering material.
These abutment means are, for example, formed by a recessed portion 13 of the arm.
The arm and the recessed portion may likewise be provided with barbs forming means for combing a sampling brush, in order to cause the elements sampled and held on the brush to fall into the strainer-like filtering means if it is not

desired to deposit the brush in the strainer-forming means.
It is then intended that the suspension may be extracted, for example, by an extraction pipette introduced into the tube 7, permitting the retrieval of the different levels of the suspension between the filtering means and the decantation cone.
Naturally, other embodiments may also be envisaged.
Thus, for example, a variant of the flask is shown in Figure 3.
The flask, generally indicated 1, and its tube, generally indicated 7, can in fact be seen in Figure 3.
The cover, generally indicated 10, which is adapted to be screwed onto the corresponding end of the flask 1, can also be seen in this drawing.
According to the embodiment shown in Figure 3, the cover 10 comprises, facing the corresponding end of the tube, at least one piercable and self-sealing region or portion through which the extraction pipette can pass.
In the embodiment illustrated, this cover comprises such a region, generally indicated 10a, provided, for example, in the centre of the cover 10, allowing the pipette or any other extraction means to pass through.
Piercable and self-sealing regions of this type are already known per se in the prior art.

They will not therefore be described in greater detail below.
It will likewise be noted that this region is adapted to come to bear against the corresponding end of the tube 7 during the screwing of the cover onto the remainder of the flask 1, to ensure optimal leaktightness between the tube 7 and the remainder of the flask, thus preventing any contamination.
Naturally, yet further embodiments may be envisaged.







CLAIMS
1. Flask for preparing a fixer-based cytological suspension, equipped with filtering means (4) at least partially immersed in the suspension, characterized in that the filtering means (4) are in the form of a web of filtering material forming a strainer, whereof the periphery (5) is fixed to the flask and whereof the centre (6) is connected to a tube (7) that extends towards the opening (2) of the flask, is associated with means (8) for holding it in position in the flask, and is adapted to allow through a pipette for extracting the suspension.
2. Flask according to Claim 1, characterized in that the upper part (9) of the flask is adapted to receive a cover (10) .
3. Flask according to Claim 2, characterized in that the cover (10) and the corresponding part (9) of the flask (1) comprise complementary screwing means.
4. Flask according to Claim 2 or Claim 3, characterized in that the cover (10) comprises, facing the corresponding end of the tube (7)f at least one piercable and self-sealing portion (10a) through which the extraction pipette can pass, and which is adapted to come to bear against that end of the tube (7) in order to ensure leaktightness between the tube (7) and the remainder of the flask (1).
5. Flask according to any one of the preceding claims, characterized in that the lower part of the flask (1) comprises means (11) forming a decantation cone.

6. Flask according to any one of the preceding claims,
characterized in that the means (8) for holding the tube (7)
in the flask comprise position-maintaining arms extending
between the flask (1) and the tube (7).
7. Flask according to Claim 6, characterized in that one (12) of the arms comprises abutment means (13) for enabling a sampling brush to be detached from a manipulating handle in order for the brush to fall into the strainer.
8. Flask according to any one of the preceding claims, characterized in that one of the arms (12) comprises barbs for combing a sampling brush in order to cause the elements sampled thereby to fall into the strainer.


Documents:

2305-chenp-2007 amended pages of specification 01-02-2011.pdf

2305-CHENP-2007 CORRESPONDENCE OTHERS 01-02-2011.pdf

2305-chenp-2007 form-1 01-02-2011.pdf

2305-chenp-2007 form-3 01-02-2011.pdf

2305-CHENP-2007 OTHER PATENT DOCUMENT 01-02-2011.pdf

2305-CHENP-2007 AMENDED CLAIMS 01-09-2010.pdf

2305-CHENP-2007 AMENDED PAGES OF SPECIFICATION 01-09-2010.pdf

2305-CHENP-2007 ASSIGNMENT 12-11-2010.pdf

2305-CHENP-2007 CORRESPONDENCE OTHERS 01-09-2010.pdf

2305-CHENP-2007 CORRESPONDENCE OTHERS 24-06-2010.pdf

2305-chenp-2007 form-3 01-09-2010.pdf

2305-CHENP-2007 FORM-6 12-11-2010.pdf

2305-CHENP-2007 POWER OF ATTORNEY 01-09-2010.pdf

2305-chenp-2007 power of attorney 12-11-2010.pdf

2305-chenp-2007-abstract.pdf

2305-chenp-2007-claims.pdf

2305-chenp-2007-correspondnece-others.pdf

2305-chenp-2007-description(complete).pdf

2305-chenp-2007-drawings.pdf

2305-chenp-2007-form 1.pdf

2305-chenp-2007-form 3.pdf

2305-chenp-2007-form 5.pdf

2305-chenp-2007-form18.pdf

2305-chenp-2007-pct.pdf


Patent Number 246851
Indian Patent Application Number 2305/CHENP/2007
PG Journal Number 12/2011
Publication Date 25-Mar-2011
Grant Date 17-Mar-2011
Date of Filing 29-May-2007
Name of Patentee MACLIP
Applicant Address 161 Bis, Avenue Jean Jaures, 92140 Clamart
Inventors:
# Inventor's Name Inventor's Address
1 PELTIER, Eric 161 bis, avenue Jean Jaurès, F-92140 CLAMART
PCT International Classification Number C12M 1/24
PCT International Application Number PCT/FR05/02953
PCT International Filing date 2005-11-28
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 0412710 2004-11-30 France