Title of Invention

PREPARATION OF MICROBIOCIDAL CATIONIC QUATERNARY AMMONIUM PRODUCT COMPOSITIONS

Abstract The present invention concerns a process for manufacturing of microbiocidal cross-linked cationic quaternary ammonium compounds poly (oxyethylene (Dialkylimino) ethylene chloride) of the formula Wherein R1 & R2 are alkyl group, where R1 is methyl, ethyl, propyl or isopropyl & R2 is myristyl, lauryl, coco, Oleyl amine, Octyl, palmityl, decyl prepared by condensing a fatty alkyl amine and ammonia or their chlorides with epichlorohydrin and diluted to desired concentrations with water.
Full Text ABSTRACT
The present invention concerns a process for manufacturing of microbiocidal cross-linked cationic quaternary ammonium compounds poly (oxyethylene (Dialkylimino) ethylene chloride) of the formula

Wherein R1 & R2 are alkyl group, where R1 is methyl, ethyl, propyl or isopropyl & R2 is myristyl, lauryl, coco, Oleyl amine, Octyl, palmityl, decyl prepared by condensing a fatty alkyl amine and ammonia or their chlorides with epichlorohydrin and diluted to desired concentrations with water.

FORM-2
THE PATENT ACT, 1970
(39 of 1970)
&
THE PATENT RULES, 2003
COMPLETE SPECIFICATION
(See section 10 and Rule 13)
PREPARATION OF MICROBICIDAL CATIONIC, QUATERNARY AMMONIUM PRODUCT COMPOSITIONS
THERMAX LIMITED
An Indian Company
of D-13, MIDC Industrial Area, R.D. Aga Road,
Chinchwad, Pune-411019,
Maharashtra India.
THE FOLLOWING SPECIFICATION PARTICULARLY DESCRIBES THE INVENTION AND THE MANNER IN WHICH IT IS TO BE PERFORMED.

TITLE
Preparation of microbiocidal cationic, quaternary ammonium product compositions.
FIELD OF INVENTION
This invention relates to a process for manufacturing cross-linked cationic quaternary ammonium compounds of outstanding efficiency in particular as biocides in controlling the growth of bacteria in commercial and industrial cooling and process water.
INTRODUCTION
The degradative effect of micro-organisms in cooling tower treatment is well known. Inhibition of growth of bacteria has been the objective of a large number of research projects and patents. Quaternary ammonium compounds have found utility for the treatment of water used in various commercial and industrial cooling systems and in swimming pools.
This invention relates to cationic, water-soluble, Fatty alkyl amine-epichlorohydrin reaction compositions and to the uses of these products in water treatment as biocides. The cationic products of this invention are also effective in controlling the growth of algae, bacteria in commercial and industrial cooling and process water. Such commercially available products are manufactured by quaternisation reaction fatty alkyl amine with benzyl chloride etc. However these products may require higher dosages to achieve required performance.
Therefore, a principal object of this invention is to provide new cationic, water-soluble, amine-epichlorohydrin reaction. It is another object of our invention to provide methods for preparation of improving biocidal properties in industrial cooling towers.
BACKGROUND OF THE INVENTION
US20060089426A discloses alkoxylated epoxide-amine adducts having a number-average molecular weight of more than 500 g/mol, which are preparable by reacting A) mono- and/or polyepoxides having at least 8
2

carbon atoms with B) primary and/or secondary amines and/or primary and/or secondary alkanolamines and/or secondary alkylalkanolamines, to form an adduct having one or more secondary OH groups, and subsequently alkoxylating the adduct with C) alkylene oxides.
US3904533 discloses certain novel combinations of fabric conditioners and optical brighteners. The novel formulations comprise a mixture containing from 99.5 to 80 parts by weight of a fabric conditioner selected from the group consisting of diethyl amino ethanol-stearamide-ethyl sulfates; the reaction product of an amine having the formula R1 NH2 and an epichlorohydrin.
Adducts of epichlorohydrin with reaction products of polyalkylenepolyamines and aliphatic dicarboxylic acids are described e.g. in British Patent No. 865,727; adducts of epichlorohydrin with reaction products of dicyandiamide and diethylenetriamine or triethylenetetramine are described e.g. in German "Offenlegungsschrift" No. 2,710,061 and in British Patent No. 1,125,486; adducts of epichlorohydrin with reaction products of diethylenetriamine, dicyandiamide and dicarboxylic acids which are free or preferably esterified with lower alkanols, in particular dimethyl adipate, are described e.g. in British Patent No. 1,125,486.
US4956049 discloses an adduct of epichlorohydrin with a reaction product of triethylenetetraamine and dicyandiamide, an adduct of epichlorohydrin with a reaction product of diethylenetriamine, dicyandiamide and dimethyl adipate, a reaction product of diacyandiamide, formaldehyde, ammonium chloride and ethylenediamine, an adduct of epichlorohydrin with a poly-N-methyl diallyl amine, and a copolymer of adipic acid and dimethylaminohydroxypropyl diethylenetriamine.
US3943255 discloses Active microbiocides prepared by reacting a long-chain N alkyl diamine such as cocodiamine in molar amounts with 0.5-3.0 moles of epichlorohydrin under controlled conditions and then terminating the active end groups by reacting with 0.5-3.0 moles of a tri lower alkylamine, such as trimethylamine. The poly quaternary nitrogen
3

compounds produced are effective at 25 ppm levels in recirculating systems against bacteria, such as A. aerogenes. In inhibition tests these compounds have also proved effective against fungi, such as A. niger.
OBJECT OF THE INVENTION
The object of the invention is to provide a process for manufacturing cross-linked cationic quaternary ammonium compounds poly (oxyethylene (Dialkylimino) ethylene chloride).
Another object of the invention is to take advantage of the cationic, quaternary compositions of outstanding efficiency in particular as biocides in controlling the growth of bacteria in commercial and industrial cooling and process water.
SUMMARY OF THE INVENTION
According to this invention, therefore there is provided a process for manufacturing cross-linked cationic quaternary ammonium compounds poly (oxyethylene (Dialkylimino) ethylene chloride) of the formula

Wherein R1 & R2 are alkyl group, where R1 is methyl, ethyl, propyl or isopropyl & R2 is myristyl, lauryl, coco, Oleyl, Octyl, palmityl, decyl etc ; comprising the following steps,
a) mixing fatty alkyl amine, alcohol and water in a predetermined ratio to form an amine solution in the pH range of 4 to 9,
b) stirring and cooling the amine solution to 5 to 40 °C,
c) adding epichlorohydrin drop wise in the amine solution at 5— to 40 °C with cooling to get a reaction mixture,
d) allowing the reaction mixture to stand at 5 to 40 °C for about 10— to 120 min,
4

e) heating the reaction mixture in step d slowly to a temperature in the range of 40 to 100°C, preferably in the range of 45 to 95 °C, more preferably in the range of 55 to 85 °C, most preferably at 60to80 °C and allowing the reaction mixture to stand for 2to 10 hours,
f) cooling the reaction mixture in step e to a temperature in the range of 40to 80 °C and adding water and allowing the reaction mixture to stand at temperature in the range of 40 to 80 °C for 30 to 180 minutes & then cooling the reaction mixture to temperature in the range of 10 to 40°C and in the pH range of 7 to 9 to obtain the cross-linked cationic quaternary ammonium compounds.
In accordance with one embodiment of the invention, the fatty alkyl amine consists of compounds selected from a group of compounds consisting of fatty alkyl amine of the formula R1,R2—(N)X, in which R1 represents methyl, ethyl, propyl or isopropyl and R2 represents myristyl, lauryl, coco, Oleyl, Octyl, palmityl and decyl etc.
Typically, the mass of the Fatty alkyl amine ranges from 45 to 60% of the total mass.
Typically, the molar ratio of fatty alkyl amine compound is preferably in the range of 1: (1.1 to 1.2) moles of epichlorohydrin.
Typically, the molar ratio of fatty alkyl amine mixture with ammonia & ammonium salt is preferably in the range of 1: (1.1 to 1.2) moles of epichlorohydrin.
Typically, the water content is in the range of 20 to 90%, preferably in the range of 30 to 80% of the total mass of the reaction mixture.
In accordance with another embodiment of the invention, the alcohol consists of at least an alcohol selected from a group of alcohols consisting of methyl alcohol, ethyl alcohol and isopropyl alcohol.
Typically, the alcohol content is in the range of 20 to 90%, preferably in the range of
5

30 to 80% of the total mass of the reaction mixture.
DETAILED DESCRIPTION OF THE INVENTION
The invention thus provides a cationic quaternary ammonium product obtained by reaction of Fatty alkyl amine and ammonia & their chloride salts with epichlorohydrin.
The invention provides a cationic quaternary ammonium product obtained by reaction of Fatty alkyl amine (represented by dialkylimino hydroxy ethylene chloride where alkyl group represents myristyldimethylamine, lauryldimethylamine, cocodimethylamine, Oleyl dimethylamine, octyldimethylamine, palmityldimethylamine, decyldimethylamine etc. & mixtures of such amines) with epichlorohydrin. Ammonia & their salts act as a cross linking agents. In absence of ammonia or their salts simple addition compound of fatty alkyl amine & epichlorohydrin is formed.
According to a preferred embodiment of the invention thus provides polycationic, polyquaternary polymers obtained by reaction of an fatty alkyl amines of the formula (R1,R2)N & Ammonia or Ammonium salts with epichlorohydrin.
The fatty alkyl amine are represented by the formula R1,R2—(N)x1, in which R1 represents methyl and R2 represents myristyl, lauryl, coco, Oleyl, Octyl, palmityl, decyl etc. One may use mixtures of such amines in various amounts with epichlorohydrin in the ratio of (1 to 1.2) moles of epichlorohydrin for every mole of compound.
The molar ratio of fatty amine compound or mixture with ammonia & their salt epichlorohydrin is preferably in the range of 1: (1.1 to 1.2) moles, of epichlorohydrin per mole of compound.
The reaction of fatty alkyl amine with epichlorohydrin is preferably carried out in the presence of alcohol & water as solvent media. The alcohols used for this reaction are water soluble alcohol viz. methyl alcohol, ethyl alcohol, isopropyl alcohol and mixtures of such alcohols. This reaction is an addition reaction of the epichlorohydrin to amine, with opening of the epoxy ring. This reaction is exothermic and the reaction temperature is preferably kept
6

below 100°C, more preferably in the range of 40-80 °C with cooling. The epichlorohydrin reacts with the available amine groups of fatty alkyl amine.
The reaction of fatty alkyl amine with epichlorohydrin is carried out suitably in aqueous medium, e.g. at a water content in the range of 20 to 90%, preferably 30 to 80%, referred to the total weight of the aqueous reaction mixture, and preferably with heating, e.g. at a temperature in the range of 40 to 100 °C, preferably 45 to 95°C. During the reaction, at least at the beginning, the basicity of the fatty alkyl amine as per formula R1,R2—(N) is sufficient for the quaternizing alkylation with the chloride where Rl represents methyl and R2 represents myristyl, lauryl, coco, Oleyl, Octyl, palmityl, decyl etc. Mixtures of such amines may be used.
The pH of the reaction mixture is preferably in the range of 4 to 9, at the beginning being preferably in the range of 7 to 9. As reaction proceeds, the alkalinity of the mixture and the concentration of amine diminish. When the reaction has completed or has reached the desired degree, the reaction mixture is suitably diluted by addition of water.
Among the above products (P) the cross-linked ones are preferred. The polymer product (P) can be represented by the formula poly (oxyethylene (Dialkylimino) ethylene chloride) and can be shown by general formula

R1&R2 are alkyl group Where R1 is methyl, ethyl, propyl, isopropyl &R2 is. myristyl, lauryl, coco, Oleyl, Octyl, palmityl, decyl etc.
The so produced compositions are ready for use or may, if desired, be adjusted in polymer product (P) content by dilution with water or evaporation or be desalinated and optionally concentrated by membrane filtration through a semi permeable membrane.
7

The concentration of cationic composition in the aqueous solution as produced is preferably in the range of 10 to 80% by weight, more preferably 20 to 70% by weight.
The degradative effect of micro-organisms in cooling tower treatment is well known. Inhibition of growth of bacteria has been the objective of a large number of research projects and patents. Quaternary ammonium compounds have found utility for the treatment of water used in various commercial and industrial cooling systems and in swimming pools. We have found that the cationic compositions of this invention are effective against bacteria, in water systems even when used in very low concentrations. The products are readily water soluble and can be diluted with water to any desired concentrations. Other advantages are long shelf life, the lack of corrosiveness. Concentrations which are suitable for the control of microorganisms vary from 0.5 to 600 parts per million based on the weight of the water being treated.
It has now surprisingly been found that the above defined cationic, quaternary compositions are of outstanding efficiency in particular as biocides in controlling the growth of, bacteria in commercial and industrial cooling and process water.
In order to disclose the nature of the present invention still more clearly, the following illustrative examples will be given. It is to be understood, however, that the invention is not to be limited to the specific conditions or details set forth in these.
Thus it is apparent that there has been provided, in accordance with the invention, a product and process that fully satisfies the objects, aims, and advantages set forth above. While the invention has been described in conjunction with specific embodiments thereof, it is evident that many alternatives, modifications, and variations will be apparent to those skilled in the art in light of the foregoing description. Accordingly, it is intended to embrace all such alternatives, modifications, and variations as fall within the spirit and broad scope of the appended claims.
8

EXAMPLES
In the following Examples parts and percentages are by weight, if not otherwise indicated; parts by weight relate to parts by volume as grams to millilitres. The temperatures are indicated in degrees Celsius.
Example 1
In a reactor equipped with heating &cooling device, thermometer, condenser; 240 parts of Myristyl dimethyl amine are mixed with 30 parts of isopropyl alcohol and 12 gms of water to form a solution. The pH of the solution was measured on pH meter & it was 9. The mixture is stirred and cooled to 15 °C. 102 parts of epichlorohydrin are added drop wise over one hour at 15-20 °C with cooling. The reaction mixture is held at 15-20 °C for about 30 min. The reaction mixture is heated slowly to 80 °C and held for 4 hours. The mixture is then cooled to 65 °C and 311 parts of water are added. The mixture is held at 65 °C for 1 hour & then cooled to 20 °C. The product is yellow coloured liquid.
This product after serial dilution was dosed in industrial cooling tower sample having initial count as 1.2*107. As a standard biocide commercially available Quat (Myristyl dimethyl benzyammonium chloride) was used .The results of % kill are summarized below in table no1
Table No.1

Dose of Biocide Example 1 product Quat
15 ppm 26% 22. %
20 ppm 28% 26%
40 ppm 56% 52%
9

Example 2
In a reactor equipped with heating & cooling device, thermometer, condenser 168 parts of Myristyl dimethyl amine are mixed with 30 parts of isopropyl alcohol and 42.75 gms of water to form a solution. 16 parts of ammonium chloride are added to this solution. The pH of the solution was measured on pH meter & it was 9. The mixture is stirred and cooled to 15 °C. 102 parts of epichlorohydrin are added drop wise over one hour at 15-20 °C with cooling. The reaction mixture is held at 15-20 °C for about 30 min. The reaction mixture is heated slowly to 80 °C and held for 4 hours. The. viscosity of mixture is increased during this period. The mixture is then cooled to 65 °C and 214.5 parts of water are added. The mixture is held at 65 °C for 1 hour & then cooled to 20 °C.The product is yellow coloured viscous liquid.
This product after serial dilution was dosed in industrial cooling tower sample having initial count as 1.2*107 .As a standard biocide commercially available Quat (Myristyl dimethyl benzyammonium chloride) was used. The results of % kill are summarized below in table no2
Table no.2

Dose of Biocide Example 2 product Quat
15 ppm 66 % 20. %
20 ppm 76 % 29 %
40 ppm >95 % 50%
Example 3
In a reactor equipped with heating &cooling device thermometer, condenser 260 parts of Lauryl dimethyl amine are mixed with 30 parts of isopropyl alcohol and 60.5 Gms of water to form a solution. The pH of solution was measured on pH meter & it was 9. The mixture is stirred and cooled to 15 °C. 102 parts of epichlorohydrin are added drop wise over one hour at 15-
10

20 °C with cooling. The reaction mixture is held at 15-20 °C for about 30 min .The reaction mixture is heated slowly to 80 degree C and held for 4 hours. The mixture is then cooled to 65 °C and 373.5 parts of water are added. The mixture is held at 65 °C for 1 hour & then cooled to 20 °C. The product is yellow coloured liquid.
This product after serial dilution was dosed in industrial cooling tower sample having initial count as 1.2*107. As a standard biocide commercially available Quat (Lauryl dimethyl benzyammonium chloride) was used. The results of % kill are summarised below in table no.3
Table no.3

Dose of Biocide Example 3 product Quat
15 ppm 23% 20. %
20 ppm 32% 29%
40 ppm 54% 50%
Example 4
In a reactor equipped with heating & cooling device, thermometer, condenser 182 parts of lauryl dimethyl amine are mixed with 30 parts of isopropyl alcohol and 50.5 gms of water to form a solution. 38 parts of ammonium chloride are added to this solution. The pH of solution was measured on pH meter & it was 9. The mixture is stirred and cooled to 15 °C. 102 parts of epichlorohydrin are added drop wise over one hour at 15-20 °C with cooling. The reaction mixture is held at 15-20 °C for about 30 min. The reaction mixture is heated slowly to 80 °C and held for 4 hours. The viscosity of mixture is increased during this period. The mixture is then cooled to 65 °C and 241.5 parts of water are added. The mixture is held at 65 °C for 1hour & then cooled to 20 °C. The product is yellow coloured viscous liquid.
11

This products after serial dilution was dosed in industrial cooling tower sample having initial count as 1.2*10sup7 .As a standard biocide commercially available Quat (Lauryl dimethyl benzyammonium chloride) was used. The results are summarized below in table no.4
Table no.4

Dose of Biocide Example 4 product Quat
15 ppm 40% 20. %
20 ppm 61% 29 %
40 ppm 72% 50%
Example 5
In a reactor equipped with heating &cooling device thermometer, condenser 72 parts of Myristyl dimethyl amine are mixed with 30 parts of isopropyl alcohol to form a solution. 47.6 parts of 25% ammonia are added to this solution. The pH of the solution was measured on pH meter &adjusted to 9 using 5% formic acid The mixture is stirred and cooled to 15 °C. 102 parts of epichlorohydrin are added drop wise over one hour at 15-20 °C with cooling. The reaction mixture is held at 15-20 °C for about 30 min. The reaction mixture is heated slowly to 80 °C and held for 4 hours. The viscosity of mixture is increased during this period. The mixture is then cooled to 65 °C and 120 parts of water are added. The mixture is held at 65 °C for 1 hour & then cooled to 20 °C. The product is yellow coloured viscous liquid.
This products after serial dilution was dosed in industrial cooling tower sample having initial count as 1.2*107 .As a standard biocide commercially available Quat (myristyl dimethyl benzyammonium chloride) was used .The results are summarized below in table no.5
12

Table no.5

Dose of Biocide Example 5 product Quat
15 ppm 85 % 20. %
20 ppm >95 % 29 %
40 ppm >95% 50%
Example 6
In a reactor equipped with heating &cooling device thermometer, condenser 72 parts of Myristyl dimethylamine are mixed with 30 parts of isopropyl alcohol and 22.94 Gms of water to form a solution. 37.75 parts of ammonium chloride are added to this solution. The pH of the solution was measured on pH meter &adjusted to 9 using 5% formic acid .The mixture is stirred and cooled to 15 °C. 102 parts of epichlorohydrin are added drop wise over one hour at 15-20 °C with cooling. The reaction mixture is held at 15-20 °C for about 30 min. The reaction mixture is heated slowly to 80 °C and held for 4 hours. The viscosity of mixture is increased during this period. The mixture is then cooled to 65.degree. C. and 196 parts of water are added. The mixture is held at 65 °C for 1 hour & then cooled to 20 °C. The product is yellow coloured viscous liquid.
This product after serial dilution was dosed in industrial cooling tower sample having initial count as 1.2*107. As a standard biocide commercially available Quat (myristyl dimethyl benzyammonium chloride) was used. The results are summarized below in table no. 6.
13

Table no.6

Dose of Biocide Example 6 product Quat
15 ppm 83% 20. %
20 ppm >95% 29 %
40 ppm >95% 50%
Example 7
In a reactor equipped with heating & cooling device, thermometer, condenser 168 parts of Myristyl dimethylamine are mixed with 30 parts of isopropyl alcohol and 23.48 Gms of water to form a solution. 20.4 parts of 25% ammonia are added to this solution. The pH of the solution was measured on pH meter &adjusted with 5% formic acid to 9. The mixture is stirred and cooled to 15 °C. 102 parts of epichlorohydrin are added drop wise over one hour at 15-20°C with cooling. The reaction mixture is held at 15-20 °C for about 30 min. The reaction mixture is heated slowly to 80 °C and held for 4 hours. The viscosity of mixture is increased during this period. The mixture is then cooled to 65 °C and 206.7 parts of water are added. The mixture is held at 65 °C for 1 hour & then cooled to 20 °C.The product is yellow coloured viscous liquid.
This product after serial dilution was dosed in industrial cooling tower sample having initial count as 1.2*107. As a standard biocide commercially available Quat (myristyl dimethyl benzyammonium chloride) was used. The results are summarised below in table no.7
14

Table no.7

Dose of Biocide Example 7 product Quat
15 ppm 46% 20. %
20 ppm 67% 29 %
40 ppm 78% 50%
Example 8
In a reactor equipped with heating &cooling device ,thermometer , condenser 182 parts of Lauryl dimethyl amine are mixed with 30 parts of isopropyl alcohol and 20.6 gms of water to form a solution. 20.4 parts of 25% ammonia are added to this solution. The pH of the solution was measured on pH meter & adjusted with 5% formic acid to 9. The mixture is stirred and cooled to 15 °C. 102 parts of epichlorohydrin are added drop wise over one hour at 15-20 °C with cooling. The reaction mixture is held at 15-20 °C for about 30 min. The reaction mixture is heated slowly to 80 °C and held for 4 hours. The viscosity of mixture is increased during this period. The mixture is then cooled to 65 °C and 214.5 parts of water are added. The mixture is held at 65 °C for 1 hour & then cooled to 20 °C. The product is yellow coloured viscous liquid.
This product after serial dilution was dosed in industrial cooling tower sample having initial count as 1.2*107. As a standard biocide commercially vailable Quat (myristyl dimethyl benzyammonium chloride) was used The results are summarised below in table no.8
15

Table no.8

Dose of Biocide Example 8 product Quat
15 ppm 73% 20. %
20 ppm 80 % 29 %
40 ppm >95 % 50%
Although the invention herein has been described with reference to particular embodiments, it is to be understood that these embodiments are merely illustrative of the principles and applications of the present invention. It is therefore to be understood that numerous modifications may be made to the illustrative embodiments and that other arrangements may be devised without departing from the spirit and scope of the present invention as defined by the appended claims.
16

We Claim:
1. A process for manufacturing cross-linked cationic quaternary ammonium compounds poly (oxyethylene (Dialkylimino) ethylene chloride) of the formula

Wherein R1 & R2 are alkyl group, where R1 is methyl, ethyl, propyl or isopropyl & R2 is myristyl, lauryl, coco, Oleyl, Octyl, palmityl, decyl; comprising the following steps,
a) mixing fatty alkyl amine, alcohol and water in a predetermined ratio to form an amine solution in the pH range of 4 to 9,
b) stirring and cooling the amine solution to 5 to 40 °C,
c) adding epichlorohydrin drop wise in the amine solution at 5 to 40°C with cooling to get a reaction mixture,
d) allowing the reaction mixture to stand at 5to 40 °C for about 10 to 120 min,
e) heating the reaction mixture in step d slowly to a temperature in the range of 40 to 100 °C, preferably in the range of 45 to 95 °C, more preferably in the range of 55to 85 °C, most preferably at 60to 80 °C and allowing the reaction mixture to stand for 2 to 10hours
f) cooling the reaction mixture in step e to a temperature in the range of 40 to 80 °C and adding water and allowing the reaction mixture to stand at temperature in the range of 40 to 80 °C for 30 to 180 minutes and then cooling the reaction mixture to temperature in the range of 10 to 40
17

°C and in the pH range of 7 to 9 to obtain the cross-linked cationic quaternary ammonium compounds.
2. A process for manufacturing cross-linked cationic quaternary ammonium compounds as claimed in claim 1, wherein the fatty alkyl amine consists of compounds selected from a group of compounds consisting of fatty alkyl amine of the formula R1,R2—(N)X1 in which R1 represents methyl, ethyl, propyl or isopropyl and R2 represents myristyl, lauryl, coco, Oleyl, Octyl, palmityl and decyl.
3. A process for manufacturing cross-linked cationic quaternary ammonium compounds as claimed in claim 1, wherein the mass of the Fatty alkyl amine ranges from 45 to 60% of the total mass.
4. A process for manufacturing cross-linked cationic quaternary ammonium compounds as claimed in claim 1, wherein the molar ratio of fatty alkyl amine compound is preferably in the range of 1: (1.1 to 1.2) moles of epichlorohydrin.
5. A process for manufacturing cross-linked cationic quaternary ammonium compounds as claimed in claim 1, wherein the molar ratio of fatty alkyl amine mixture with ammonia & ammonium salt is preferably in the range of 1: (1.1 to 1.2) moles of epichlorohydrin.
6. A process for manufacturing cross-linked cationic quaternary ammonium compounds as claimed in claim 1, wherein the water content is in the range of 20 to 90%, preferably in the range of 30 to 80% of the total mass of the reaction mixture.
7. A process for manufacturing cross-linked cationic quaternary ammonium compounds as claimed in claim 1, wherein the alcohol consists of at least an alcohol selected from a group of alcohols consisting of methyl alcohol, ethyl alcohol and isopropyl alcohol.
8. A process for manufacturing cross-linked cationic quaternary ammonium compounds as claimed in claim 1, wherein the alcohol content is in the
18

range of 20 to 90%, preferably in the range of 30 to 80% of the total mass of the reaction mixture.
9. A process for manufacturing of cross-linked cationic quaternary ammonium compounds substantially as herein described with reference to the examples and figures accompanying the specification.
10. A product prepared by the process for manufacturing cross-linked cationic quaternary ammonium compounds as claimed in claim 1 to 9, substantially as herein described with reference to the examples and figures accompanying the specification
MOHAN DEWAN
OF R.K.DEWAN & COMPANY APPLICANTS' PATENT ATTORNEY
Dated this 30th day of August, 2006
19

Documents:

1368-mum-2006-abstract(30-8-2006).pdf

1368-mum-2006-abstract(granted)-(23-2-2011).pdf

1368-mum-2006-abstract.doc

1368-mum-2006-abstract.pdf

1368-mum-2006-cancelled pages(3-2-2011).pdf

1368-mum-2006-claims(30-8-2006).pdf

1368-MUM-2006-CLAIMS(AMENDED)-(3-2-2011).pdf

1368-mum-2006-claims(granted)-(23-2-2011).pdf

1368-MUM-2006-CLAIMS(MARKED COPY)-(3-2-2011).pdf

1368-mum-2006-claims.doc

1368-mum-2006-claims.pdf

1368-mum-2006-correspondence recieved.pdf

1368-mum-2006-correspondence(22-4-2008).pdf

1368-mum-2006-correspondence(ipo)-(23-2-2011).pdf

1368-mum-2006-description (complete).pdf

1368-mum-2006-description(complete)-(30-8-2006).pdf

1368-mum-2006-description(granted)-(23-2-2011).pdf

1368-mum-2006-form 18(22-4-2008).pdf

1368-mum-2006-form 2(30-8-2006).pdf

1368-mum-2006-form 2(granted)-(23-2-2011).pdf

1368-mum-2006-form 2(title page)-(30-8-2006).pdf

1368-mum-2006-form 2(title page)-(granted)-(23-2-2011).pdf

1368-mum-2006-form-1.pdf

1368-mum-2006-form-2.doc

1368-mum-2006-form-2.pdf

1368-mum-2006-form-26.pdf

1368-mum-2006-form-3.pdf

1368-MUM-2006-POWER OF AUTHORITY(3-2-2011).pdf

1368-MUM-2006-REPLY TO EXAMINATION REPORT(29-6-2010).pdf

1368-MUM-2006-REPLY TO HEARING(3-2-2011).pdf

abstract1.jpg


Patent Number 246292
Indian Patent Application Number 1368/MUM/2006
PG Journal Number 08/2011
Publication Date 25-Feb-2011
Grant Date 23-Feb-2011
Date of Filing 30-Aug-2006
Name of Patentee THERMAX LIMITED
Applicant Address D-13,MIDC INDUSTRIAL AREA, R.D.AGA ROAD,CHINCHWAD, PUNE-411 019,
Inventors:
# Inventor's Name Inventor's Address
1 DESHPANDE KIRAN VASUDEO D-13,MIDC INDUSTRIAL AREA, R.D.AGA ROAD,CHINCHWAD, PUNE-411 019,
2 VAIDYA SEKHAR JAYARAM D-13,MIDC Industrial Area, R.D.Aga Road,Chinchwad, Pune-411 019,
PCT International Classification Number C07D295/00, C07C219/00
PCT International Application Number N/A
PCT International Filing date
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 NA