Title of Invention | DRY POWDER INHALER DEVICE |
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Abstract | The invention is a DRY POWDER INHALER DEVICE. The device is a capsule based single dose reusable DRY POWDER INHALER DEVICE. My "DRY POWDER INHALER DEVICE" is made for those patients, who are suffering from ASTHMA, COPD or any kind of diseases, where drug powder should be inhaled. My DRY POWDER INHALER DEVICE has five parts. A). CAPSULE CHAMBER FRONT NOZZLE (fig-1). B) PUSHER CHAMBER HOUSING (fig-2). C). SPRING(fig-5 ) . D). PUSHER SPINDLE WITH NEEDLE (fig-4 ). E). END CAP(fig-3). The PUSHER SPINDLE WITH NEEDLE can be a single part of my device or may be made of two parts i.e. needle and pusher spindle. My device can be made of four parts also i.e. the END CAP may be the extended part of PUSHER CHAMBER HOUSING. My device can be made up of medical grade POLY CARBON or medical grade STEEL. My DRY POWDER INHALER DEVICE has a CAPSULE CHAMBER, Which takes shape as a capsule chamber when CAPSULE CHAMBER FRONT NOZZLE(fig-1) and PUSHER CHAMBER HOUSING(fig-2) are joined/locked together. Both CAPSULE CHAMBER FRONT NOZZLE and PUSHER CHAMBER HOUSING are having half of capsule chamber. PUSHER CHAMBER HOUSING is a hollow part of my device and has half capsule chamber shape place to it's front side with a threaded outer body front side. The PUSHER CHAMBER HOUSING has a small hole in the middle of halt capsule chamber for the movement of PUSHER SPINDLE WITH NEEDLE (fig-4) by which the poles of installed dry powder capsule's two poles can be pierced. The hind part of PUSHER CHAMBER HOUSING is threaded, by which it can be locked/joined to END CAP. The END CAP(fig-3) is threaded in it's front side, by which it can be loked/joined to the PUSHER CHAMBER HOUSING. The END CAP has a hole in the middle portion of it's back. through which the back portion of PUSHER SPINDLE WITH NEEDLE moves when the pressure is applied. The DEVICE may be of different shapes and sizes but the technology usued behind it is the same. |
Full Text | FIELD OF INVENTION. For a long time respiratory diseases like ASTHMA and CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) are causing severe problems to asthmatics and COPD patients. Both the diseases are progressive. Therefore patients o these diseases live compromised lives. Their daily routine is always disturbed due sudden attack of respiratory distress. The asthma and COPD patients are vulnerable to seasonal changes. Asthma attack may occur due to external factors or internal factors. Till date cure to asthma and COPD is yet to be invented. Asthma and COPD patients are to be treated either by reliever or preventer or by both medicines. Asthma is chronic inflammatory disease of tracho bronchial tree with reversible broncho spasm. COPD is irreversible disease of deep lung. To control the inflammation, asthma patients have to be on steroid. COPD patient's medicines will have to go the deep lung tissues. Oral treatment of asthma and COPD is available. Oral treatments are often very effective. But oral treats are like double edge sword. In one have it is very effective and on the other hand side effects are huge. So, a new technique of medication was very much awaited. The new procedure of medication is DRY POWDER INHALER DEVICE. Through this device, low dose of drug, which is much lesser as against oral dose is required to provide relief to asthma and COPD patients. So, DRY POWDER INHALER DEVICE effectively sends medicines to tracho bronchial tree and due to low dose of medicines sides effects are very less compared to oral treatment. Page no. 1 INTRODUCTION Asthma and COPD are two chronic diseases. Only controlling of these is possible till date. Curative treatment is not found yet. Due to non availability of effective treatment procedure patients sufferings were higher. I have invented a DRY POWDER INHALER DEVICE (CAPSULE BASED) which is very much effective in controlling asthma and COPD. In existing CAPSULE BASED DRY POWDER INHALER DEVICES dry powder is released in vortex chambers. Patients need inhale that powder with high inspiratory flow. This high flow forces the DRY POWDER to get accumulated in Oropharyngeal region resulting in less drug deposition in Lungs. Therefore, the need for an effective DRY POWDER INHALER was on, to send maximum drugs in Lungs. The main obstacle to sending drugs to Lungs is ninety degree sharp bend of Oropharyngeal bend. My DEVICE has overcome that problem. In my DEVICE the capsule itself is the vortex chamber. When two poles of the installed DRY POWDER CAPSULE is pierced and inhaled through the front portion of CAPSULE CHAMBER FRONT NOZZLE then air comes in the capsule from a small hole from PUSHER CHAMBER HOUSING air passages. The air gets obstructed in the small hole and when air comes in the DRY POWDER CAPSULE then high turbulence takes place and drug powder moves out from the small hole from the CAPSULE CHAMBER FRONT NOZZLE SIDE with serpentine movement. Due this movement, drug powder remains in the air for longer period of time and easily bypasses the ninety degree sharp bend of Oropharyngeal region resulting in much higher deposition of drugs in Lungs. Thus provide more relief to the patients. My device is the most easily maneuverable device. Asthma and COPD patients now can have normal life style. page no. 2- DISADVANTAGES WITH OTHER EXISTING CAPSULE BASED DRY POWDER INHALERS A. Capsules pole side to be specifically inserted in the hole of DRY POWDER INHALER (DPI) Device. B. Capsule has to be cut or divided in two parts. C. Hole of DPI Device should be covered by finger while inhalation. D. Drug powder has to fall in a large vortex chamber of DPI Device. E. Inhalation mouth has to tightly lip. F. Asthma / COPD patients have to notice the drug powder along with capsule parts movement while inhalation. G. Capsule parts rotation is a must in the vortex chamber in such DPI Devices. H. Some powder always remains in cut/divided parts of capsule. I. Drug powder spreads throughout the inner wall of big/large vortex chamber. J. For inhalation, asthma/COPD patients inspiratory flow rate should be higher, but such patients always having low inspiratory flow rates. K. Wastage of drug powder is very high. L. Regular maintenance of DPI Devices required. Page no. ,... 3 VARIOUS PARTS OF DRY POWDER INHALER DEVICE FIG- 1: CAPSULE CHAMBER FRONT NOZZLE. FIG-2: PUSHER CHAMBER HOUSING. FIG-3:endcap. FIG-4: pusher spindle with needle. FIG-5: spring. FIG-6: assembly & sectional view of dry powder inhaler device. FIG-7: sectional assembly drawing with dry powder capsule. Page no. . 4 DESCRIPTION OF PARTS OF DRY POWDER INHALER DEVICE FIG-1: CAPSULE CHAMBER FRONT NOZZLE. It is the first part of my DRY POWDER INHALER DEVICE. Front side of CAPSULE CHAMBER FRONT NOZZLE is a hollow structure with special characteristics. Front portion is a mouth for inhalation from where drug powder goes out. Middle part of CAPSULE CHAMBER FRONT NOZZLE is made for capsule chamber in which half portion of DPI capsule can be held. Back side of CAPSULE CHAMBER FRONT NOZZLE is threaded, by which it is fitted/locked with PUSHER CHAMBER HOUSING (FIG-2). FIG-2: PUSHER CHAMBER HOUSING. PUSHER CHAMBER HOUSING is a hollow structure of my DPI Device with special characteristics. Front portion of PUSHER CHAMBER HOUSING is threaded by which it can be attached to CAPSULE CHAMBER FRONT NOZZLE (FIG-l) or detached from the same. Inner side of front portion has the provision for half of DPI capsule installation and called as half capsule chamber A SPRING (FIG-S) is placed inside the PUSHER CHAMBER HOUSING and a PUSHER SPINDLE WITH NEEDLE (FIG-4) is placed. The PUSHER SPINDLE WITH NEEDLE moves through SPRING and other parts of my DRY POWDER INHALER DEVICE but never goes outside of CAPSULE CHAMBER FRONT NOZZLE. The end portion of PUSHER CHAMBER HOUSING is threaded by which it can be attached to END CAP (FIG-3) OR DETTACHED FROM THE SAME. PUSHER CHAMBER HOUSING may have two or more holes on different portion on its body as air passage/s. FIG-3: END CAP. END CAP is situated at the end of my DRY POWDER INHALER DEVICE. It is the lock to PUSHER SPINDLE WITH NEEDLE (FIG-4). It has a hole in the middle portion through which the end portion of PUSHER SPINDLE WITH NEEDLE moves. The front inner side of END CAP is threaded by . which it can be attached to PUSHER CHAMBER HOUSING or detached from it. FIG-4: PUSHER SPINDLE WITH NEEDLE. PUSHER SPINDLE WITH NEEDLE is the only part of my DRY POWDER INHALER DEVICE which moves through all other parts but never goes outside of CAPSULE CHAMBER FRONT NOZZLE. End portion of PUSHER SPINDLE WITH NEEDLE remains outside of END CAP. The front portion of PUSHER SPINDIF WITH NFFDLF is in needle shape. This part of PUSHER SPINDLE WITH NEFDLE pierces the two poles of installed DRY POWDER CAPSULE when push is applied on the top of hind portion of PUSHER SPINDLE WITH NEEDLE. The PUSHER SPINDLE WITH NEEDLE comes back to its normal position leaving two holes on the two poles of installed DRY POWDER CAPSULE when push is lifted from it. Page no. 5 FIG-S: SPRING. SPRING is placed inside the PUSHER CHAMBER HOUSING (FIG-2). PUSHER SPINDLE WITH NEEDLE moves through it. The SPRING covers the front portion of PUSHER SPINDLE WITH NEEDLE to keep it in its normal position. The SPRING helps in the movement of PUSHER SPINDLE WITH NEEDLE. FIG-6: ASSEMBLY & SECTIONAL VIEW OF DRY POWDER INHALER DEVICE. The drawing on the top shows external view of DRY POWDER INHALER DEVICE. The drawing at the button shows the sectional view of my DRY POWDER INHALER DEVICE. FIG-7: SECTIONAL ASSEMBLY DRAWING WITH DRY POWDER CAPSULE. This drawing clearly demonstrates all parts of my DRY POWDER INHALER DEVICE. This drawing shows how the installed DRY POWDER CAPSULE is pierced in CAPSULE CHAMBER when PUSHER SPINDLE WITH NEEDLE is pushed. Parts of my DRY POWDER INHALER DEVICE are renumbered due incorporation of DRY POWDFR CAPSULE in this drawing. Page no. . 6 When the dry powder capsule is loaded in the capsule chamber of my device then a push on the back of PUSHER SPINDLE WITH NEEDLE results in two simultaneous holes on the two poles of installed capsule. The PUSHER SPINDLE WITH NEEDLE comes out from the pierced capsule when the push is released from the back of PUSHER SPINDLE WITH NEEDLE. Now the installed dry powder capsule has two holes on it's two poles. The patient, who needs to inhale medice in his/her tracho bronchial tree should inhale through CAPSULE CHAMBER FRONT NOZZLE and the medicine/medicines in dry powder capsule will reach to the site of requirement of LUNGS from the pierced capsule through CAPSULE CHAMBER FRONT NOZZLE. The empty capsule has to be taken out from the CAPSULE CHAMBER after inhalation and another dry powder capsule may be installed in the capaule chamber of my DRY POWDER INHALER DEVICE for in future use. The CAPSULE CHAMBER FRONT NOZZLE (fig -1), PUSHER CHAMBER HOUSING(fig-2) and END CAP(fig-3) are joind/locked together. SPRING(fig-5) is placed inside the PUSHER CHAMBER HOUSING and PUSHER SPINDLE WITH NEEDLE (fig-4) moves through all these parts of my DRY POWDER INHALER DEVICE. The CAPSULE CHAMBER FRONT NOZZLE and PUSHER CHAMBER HOUSING give shape to a capsule chamber when both these are joined/locked together. In this capsule chamber dry powder capsule is installed for inhalation purpose. SPRING is placed inside the hollow place of PUSHER CHAMBER HOUSING. PUSHER SPINDLE WITH NEEDLE is placed and moves through all parts of my DRY POWDER INHALER DEVICE. The hind portion of PUSHER SPINDLE WITH NEEDLE will always remain out of device, but the front portion of PUSHER SPINDLE WITH NEEDLE never come out from CAPSULE CHAMBER FRONT NOZZLE front portion. The inhalation procedure is very simple through my device. Only three steps are required to inhale the drug from my DRY POWDER INHALER DEVICE.. 1. FILL CAPSULE IN THE CAPSULE CHAMBER. 2. PUSH AND RELEASE THE BACK SIDE OF THE PUSHER SPINDLE WITH NEEDLE. 3. INHALE THE DRUG POWDER FROM THE FRONT OF CAPSULE CHAMBER FRONT NOZZLE. Fig. 7 of accomapnying drawings for over all view and Fig. 1 to 5 other drawings for five respective parts of my DRY POWDER INHALER DEVICE. Page no.7 I CLAIM 1. A DRY POWDER INHALER DEVICE comprising of CAPSULE CHAMBER FRONT NOZZLE, PUSHER CHAMBER HOUSING, PUSHER SPINDLE WITH NEEDLE, SPRING and END CAP for DRY POWDER INHALER DEVICE for Asthma, Chronic Obstructive Pulmonary Disease (COPD) and other patients who require DRY POWDER DRUGS through inhalation. 2. A Device as claimed in claim no.l, where in a CAPSULE CHAMBER FRONT NOZZLE, which is a hollow structure with special characteristics like a "half capsule chamber", "inhalation mouth" and "threaded hind portion". The threaded hind portion is for joining /setting with PUSHER CHAMBER HOUSING. Front inside portion of PUSHER CHAMBER HOUSING has a half capsule chamber and the outer part of the front portion is threaded. Theses threaded portions are for joining the CAPSULE CHAMBER FRONT NOZZLE with PUSHER CHAMBER HOUSING, after which a full capsule chambers forms. In this capsule chamber a DRY POWDER capsule is kept for inhalation purpose for patients. The body of PUSHER CHAMBER HOUSING is hollow and may have two or more holes around. These holes are used as air passages. The hind portion of PUSHER CHAMBER HOUSING is threaded to get joined/locked to the threaded portion of END CAP. A PUSHER SPINDLE WITH NEEDLE is placed inside the PUSHER CHAMBER HOUSING to pierce the installed DRY POWDER CAPSULE. The PUSHER SPINDLE WITH NEEDLE is placed through a SPRING inside the PUSHER CHAMBER HOUSING. The SPRING keeps the PUSHER SPINDLE WITH NEEDLE in its normal position after each push on the back of the PUSHER SPINDLE WITH NEEDLE. The END CAP is fitted/locked to the threaded hind portion of PUSHER CHAMBER HOUSING. The END CAP is a hollow structure and has a hole in the middle, through which the pushing end/portion of PUSHER SPINDLE WITH NEEDLE MOVES. 3. A DEVICE as claimed in claim no.l & 2 , where in the DEVICE adapted / configured to hold DRY POWDER INHALER capsule inside the CAPSULE CHAMBER and where in , the two poles of the installed capsule are pierced by PUSHER SPINDLE WITH NEEDLE through a push on the top of back portion of PUSHER SPINDLE WITH NEEDLE. 4. A DEVICE as claimed in claim no.l, 2, 3, where in the DEVICE is made up of five parts. The DEVICE is an easily maneuverable DRY POWDER INHALER DEVICE. 5. A DEVICE as claimed in claim no. 1-4, where in the PUSHER SPINDLE WITH NEEDLE can be made up of single part or two parts. Page no. 9 6. A DEVICE as claimed in claim no.1-5, where in the materials which can be used to manufacture the DEVICE can be of surgical/medical grade POLY CARBON and surgical grade steel or metals. 7. A DEVICE as claimed in claim no. 1-6, where in an installed DRY POWDER CAPSULE in CAPSULE CHAMBER of my DEVICE can be pierced and Dry Powder can be inhaled by making a small change of PUSHER CHAMBER HOUSING and PUSHER SPINDLE WITH NEEDLE. In the body of PUSHER CHAMBER HOUSING an open channel with an extended part in one side of the channel. The hind portion of PUSHER SPINDLE WITH NEEDLE can be given V shape and the vertical portion of PUSHER SPINDLE WITH NEEDLE can be placed through the channel of PUSHER CHAMBER HOUSING. The DEVICE can have same type of functional/operational activity by a pull instead of push. 8. A DEVICE as claimed in claim no. 1-7, where in an installed DRY POWDER CAPSULE in the CAPSULE CHAMBER of my DRY POWDER INHALER DEVICE can be pierced and DRY POWDER can be inhaled by making a small change in design. The different design on same technique can be done by making a small change i.e. the inside of PUSHER CHAMBER HOUSING and on the outer portion of PUSHER SPINDLE WITH NEEDLE will threaded and there will be a wheel like round structure on the hind top of PUSHER SPINDLE WITH NEEDLE. By rotating the wheel like structure the installed DRY POWDER CAPSULE in the CAPSULE CHAMBER can be pierced and DRY POWDER can be inhaled through the same technique. 9. A DEVICE as claimed in claim no. 1-8, as described wherein the description and accompanying drawings. Date-17.02.2006 (KAKALISENGUPTA) Page no. 10 The invention is a DRY POWDER INHALER DEVICE. The device is a capsule based single dose reusable DRY POWDER INHALER DEVICE. My "DRY POWDER INHALER DEVICE" is made for those patients, who are suffering from ASTHMA, COPD or any kind of diseases, where drug powder should be inhaled. My DRY POWDER INHALER DEVICE has five parts. A). CAPSULE CHAMBER FRONT NOZZLE (fig-1). B) PUSHER CHAMBER HOUSING (fig-2). C). SPRING(fig-5 ) . D). PUSHER SPINDLE WITH NEEDLE (fig-4 ). E). END CAP(fig-3). The PUSHER SPINDLE WITH NEEDLE can be a single part of my device or may be made of two parts i.e. needle and pusher spindle. My device can be made of four parts also i.e. the END CAP may be the extended part of PUSHER CHAMBER HOUSING. My device can be made up of medical grade POLY CARBON or medical grade STEEL. My DRY POWDER INHALER DEVICE has a CAPSULE CHAMBER, Which takes shape as a capsule chamber when CAPSULE CHAMBER FRONT NOZZLE(fig-1) and PUSHER CHAMBER HOUSING(fig-2) are joined/locked together. Both CAPSULE CHAMBER FRONT NOZZLE and PUSHER CHAMBER HOUSING are having half of capsule chamber. PUSHER CHAMBER HOUSING is a hollow part of my device and has half capsule chamber shape place to it's front side with a threaded outer body front side. The PUSHER CHAMBER HOUSING has a small hole in the middle of halt capsule chamber for the movement of PUSHER SPINDLE WITH NEEDLE (fig-4) by which the poles of installed dry powder capsule's two poles can be pierced. The hind part of PUSHER CHAMBER HOUSING is threaded, by which it can be locked/joined to END CAP. The END CAP(fig-3) is threaded in it's front side, by which it can be loked/joined to the PUSHER CHAMBER HOUSING. The END CAP has a hole in the middle portion of it's back. through which the back portion of PUSHER SPINDLE WITH NEEDLE moves when the pressure is applied. The DEVICE may be of different shapes and sizes but the technology usued behind it is the same. |
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00144-kol-2006-description complete.pdf
144-KOL-2006-CANCELLED PAGES.pdf
144-KOL-2006-DESCRIPTION (COMPLETE).pdf
144-kol-2006-examination report.pdf
144-kol-2006-granted-abstract.pdf
144-kol-2006-granted-claims.pdf
144-kol-2006-granted-description (complete).pdf
144-kol-2006-granted-drawings.pdf
144-kol-2006-granted-form 1.pdf
144-kol-2006-granted-form 2.pdf
144-kol-2006-granted-specification.pdf
144-kol-2006-reply to examination report.pdf
Patent Number | 243398 | ||||||||
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Indian Patent Application Number | 144/KOL/2006 | ||||||||
PG Journal Number | 42/2010 | ||||||||
Publication Date | 15-Oct-2010 | ||||||||
Grant Date | 13-Oct-2010 | ||||||||
Date of Filing | 17-Feb-2006 | ||||||||
Name of Patentee | KAKALI SENGUPTA | ||||||||
Applicant Address | MILAN PARK, MANIKPUR, KOLKATA-700079, P.O. ITALGACHA, P.S. DUMDUM, 24 PGS (N) | ||||||||
Inventors:
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PCT International Classification Number | A61M 15/00 | ||||||||
PCT International Application Number | N/A | ||||||||
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