Title of Invention

DRY POWDER INHALER DEVICE

Abstract The invention is a DRY POWDER INHALER DEVICE. The device is a capsule based single dose reusable DRY POWDER INHALER DEVICE. My "DRY POWDER INHALER DEVICE" is made for those patients, who are suffering from ASTHMA, COPD or any kind of diseases, where drug powder should be inhaled. My DRY POWDER INHALER DEVICE has five parts. A). CAPSULE CHAMBER FRONT NOZZLE (fig-1). B) PUSHER CHAMBER HOUSING (fig-2). C). SPRING(fig-5 ) . D). PUSHER SPINDLE WITH NEEDLE (fig-4 ). E). END CAP(fig-3). The PUSHER SPINDLE WITH NEEDLE can be a single part of my device or may be made of two parts i.e. needle and pusher spindle. My device can be made of four parts also i.e. the END CAP may be the extended part of PUSHER CHAMBER HOUSING. My device can be made up of medical grade POLY CARBON or medical grade STEEL. My DRY POWDER INHALER DEVICE has a CAPSULE CHAMBER, Which takes shape as a capsule chamber when CAPSULE CHAMBER FRONT NOZZLE(fig-1) and PUSHER CHAMBER HOUSING(fig-2) are joined/locked together. Both CAPSULE CHAMBER FRONT NOZZLE and PUSHER CHAMBER HOUSING are having half of capsule chamber. PUSHER CHAMBER HOUSING is a hollow part of my device and has half capsule chamber shape place to it's front side with a threaded outer body front side. The PUSHER CHAMBER HOUSING has a small hole in the middle of halt capsule chamber for the movement of PUSHER SPINDLE WITH NEEDLE (fig-4) by which the poles of installed dry powder capsule's two poles can be pierced. The hind part of PUSHER CHAMBER HOUSING is threaded, by which it can be locked/joined to END CAP. The END CAP(fig-3) is threaded in it's front side, by which it can be loked/joined to the PUSHER CHAMBER HOUSING. The END CAP has a hole in the middle portion of it's back. through which the back portion of PUSHER SPINDLE WITH NEEDLE moves when the pressure is applied. The DEVICE may be of different shapes and sizes but the technology usued behind it is the same.
Full Text FIELD OF INVENTION.
For a long time respiratory diseases like ASTHMA and CHRONIC OBSTRUCTIVE
PULMONARY DISEASE (COPD) are causing severe problems to asthmatics and COPD
patients. Both the diseases are progressive. Therefore patients o these diseases live
compromised lives. Their daily routine is always disturbed due sudden attack of respiratory
distress. The asthma and COPD patients are vulnerable to seasonal changes. Asthma attack
may occur due to external factors or internal factors. Till date cure to asthma and COPD is
yet to be invented. Asthma and COPD patients are to be treated either by reliever or
preventer or by both medicines.
Asthma is chronic inflammatory disease of tracho bronchial tree with reversible broncho
spasm. COPD is irreversible disease of deep lung. To control the inflammation, asthma
patients have to be on steroid. COPD patient's medicines will have to go the deep lung
tissues.
Oral treatment of asthma and COPD is available. Oral treatments are often very effective.
But oral treats are like double edge sword. In one have it is very effective and on the other
hand side effects are huge. So, a new technique of medication was very much awaited.
The new procedure of medication is DRY POWDER INHALER DEVICE. Through this device,
low dose of drug, which is much lesser as against oral dose is required to provide relief to
asthma and COPD patients. So, DRY POWDER INHALER DEVICE effectively sends medicines
to tracho bronchial tree and due to low dose of medicines sides effects are very less
compared to oral treatment.
Page no. 1
INTRODUCTION
Asthma and COPD are two chronic diseases. Only controlling of these is possible till date.
Curative treatment is not found yet. Due to non availability of effective treatment
procedure patients sufferings were higher. I have invented a DRY POWDER INHALER DEVICE
(CAPSULE BASED) which is very much effective in controlling asthma and COPD. In existing
CAPSULE BASED DRY POWDER INHALER DEVICES dry powder is released in vortex chambers.
Patients need inhale that powder with high inspiratory flow. This high flow forces the DRY
POWDER to get accumulated in Oropharyngeal region resulting in less drug deposition in
Lungs.
Therefore, the need for an effective DRY POWDER INHALER was on, to send maximum drugs
in Lungs. The main obstacle to sending drugs to Lungs is ninety degree sharp bend of
Oropharyngeal bend. My DEVICE has overcome that problem. In my DEVICE the capsule
itself is the vortex chamber. When two poles of the installed DRY POWDER CAPSULE is
pierced and inhaled through the front portion of CAPSULE CHAMBER FRONT NOZZLE then
air comes in the capsule from a small hole from PUSHER CHAMBER HOUSING air passages.
The air gets obstructed in the small hole and when air comes in the DRY POWDER CAPSULE
then high turbulence takes place and drug powder moves out from the small hole from the
CAPSULE CHAMBER FRONT NOZZLE SIDE with serpentine movement. Due this movement,
drug powder remains in the air for longer period of time and easily bypasses the ninety
degree sharp bend of Oropharyngeal region resulting in much higher deposition of drugs in
Lungs. Thus provide more relief to the patients.
My device is the most easily maneuverable device. Asthma and COPD patients now can
have normal life style.
page no. 2-
DISADVANTAGES WITH OTHER
EXISTING CAPSULE BASED DRY
POWDER INHALERS
A. Capsules pole side to be specifically inserted in the hole of DRY POWDER INHALER
(DPI) Device.
B. Capsule has to be cut or divided in two parts.
C. Hole of DPI Device should be covered by finger while inhalation.
D. Drug powder has to fall in a large vortex chamber of DPI Device.
E. Inhalation mouth has to tightly lip.
F. Asthma / COPD patients have to notice the drug powder along with capsule parts
movement while inhalation.
G. Capsule parts rotation is a must in the vortex chamber in such DPI Devices.
H. Some powder always remains in cut/divided parts of capsule.
I. Drug powder spreads throughout the inner wall of big/large vortex chamber.
J. For inhalation, asthma/COPD patients inspiratory flow rate should be higher, but
such patients always having low inspiratory flow rates.
K. Wastage of drug powder is very high.
L. Regular maintenance of DPI Devices required.
Page no. ,... 3
VARIOUS PARTS OF DRY POWDER
INHALER DEVICE
FIG- 1: CAPSULE CHAMBER FRONT NOZZLE.
FIG-2: PUSHER CHAMBER HOUSING.
FIG-3:endcap.
FIG-4: pusher spindle with needle.
FIG-5: spring.
FIG-6: assembly & sectional view of dry powder inhaler device.
FIG-7: sectional assembly drawing with dry powder capsule.
Page no. . 4
DESCRIPTION OF PARTS OF DRY
POWDER INHALER DEVICE
FIG-1: CAPSULE CHAMBER FRONT NOZZLE. It is the first part of my DRY POWDER INHALER DEVICE.
Front side of CAPSULE CHAMBER FRONT NOZZLE is a hollow structure with special characteristics.
Front portion is a mouth for inhalation from where drug powder goes out. Middle part of CAPSULE
CHAMBER FRONT NOZZLE is made for capsule chamber in which half portion of DPI capsule can be
held. Back side of CAPSULE CHAMBER FRONT NOZZLE is threaded, by which it is fitted/locked with
PUSHER CHAMBER HOUSING (FIG-2).
FIG-2: PUSHER CHAMBER HOUSING. PUSHER CHAMBER HOUSING is a hollow structure of my DPI
Device with special characteristics. Front portion of PUSHER CHAMBER HOUSING is threaded by
which it can be attached to CAPSULE CHAMBER FRONT NOZZLE (FIG-l) or detached from the same.
Inner side of front portion has the provision for half of DPI capsule installation and called as half
capsule chamber A SPRING (FIG-S) is placed inside the PUSHER CHAMBER HOUSING and a PUSHER
SPINDLE WITH NEEDLE (FIG-4) is placed. The PUSHER SPINDLE WITH NEEDLE moves through SPRING
and other parts of my DRY POWDER INHALER DEVICE but never goes outside of CAPSULE CHAMBER
FRONT NOZZLE. The end portion of PUSHER CHAMBER HOUSING is threaded by which it can be
attached to END CAP (FIG-3) OR DETTACHED FROM THE SAME. PUSHER CHAMBER HOUSING may
have two or more holes on different portion on its body as air passage/s.
FIG-3: END CAP. END CAP is situated at the end of my DRY POWDER INHALER DEVICE. It is the lock
to PUSHER SPINDLE WITH NEEDLE (FIG-4). It has a hole in the middle portion through which the end
portion of PUSHER SPINDLE WITH NEEDLE moves. The front inner side of END CAP is threaded by .
which it can be attached to PUSHER CHAMBER HOUSING or detached from it.
FIG-4: PUSHER SPINDLE WITH NEEDLE. PUSHER SPINDLE WITH NEEDLE is the only part of my DRY
POWDER INHALER DEVICE which moves through all other parts but never goes outside of CAPSULE
CHAMBER FRONT NOZZLE. End portion of PUSHER SPINDLE WITH NEEDLE remains outside of END
CAP. The front portion of PUSHER SPINDIF WITH NFFDLF is in needle shape. This part of PUSHER
SPINDLE WITH NEFDLE pierces the two poles of installed DRY POWDER CAPSULE when push is
applied on the top of hind portion of PUSHER SPINDLE WITH NEEDLE. The PUSHER SPINDLE WITH
NEEDLE comes back to its normal position leaving two holes on the two poles of installed DRY
POWDER CAPSULE when push is lifted from it.
Page no. 5
FIG-S: SPRING. SPRING is placed inside the PUSHER CHAMBER HOUSING (FIG-2). PUSHER SPINDLE
WITH NEEDLE moves through it. The SPRING covers the front portion of PUSHER SPINDLE WITH
NEEDLE to keep it in its normal position. The SPRING helps in the movement of PUSHER SPINDLE
WITH NEEDLE.
FIG-6: ASSEMBLY & SECTIONAL VIEW OF DRY POWDER INHALER DEVICE. The drawing on the top
shows external view of DRY POWDER INHALER DEVICE. The drawing at the button shows the
sectional view of my DRY POWDER INHALER DEVICE.
FIG-7: SECTIONAL ASSEMBLY DRAWING WITH DRY POWDER CAPSULE. This drawing clearly
demonstrates all parts of my DRY POWDER INHALER DEVICE. This drawing shows how the installed
DRY POWDER CAPSULE is pierced in CAPSULE CHAMBER when PUSHER SPINDLE WITH NEEDLE is
pushed. Parts of my DRY POWDER INHALER DEVICE are renumbered due incorporation of DRY
POWDFR CAPSULE in this drawing.
Page no. . 6
When the dry powder capsule is loaded in the capsule chamber of my device then a
push on the back of PUSHER SPINDLE WITH NEEDLE results in two simultaneous holes
on the two poles of installed capsule. The PUSHER SPINDLE WITH NEEDLE comes out
from the pierced capsule when the push is released from the back of PUSHER SPINDLE
WITH NEEDLE. Now the installed dry powder capsule has two holes on it's two poles.
The patient, who needs to inhale medice in his/her tracho bronchial tree should inhale
through CAPSULE CHAMBER FRONT NOZZLE and the medicine/medicines in dry powder
capsule will reach to the site of requirement of LUNGS from the pierced capsule through
CAPSULE CHAMBER FRONT NOZZLE. The empty capsule has to be taken out from the
CAPSULE CHAMBER after inhalation and another dry powder capsule may be installed in
the capaule chamber of my DRY POWDER INHALER DEVICE for in future use.
The CAPSULE CHAMBER FRONT NOZZLE (fig -1), PUSHER CHAMBER
HOUSING(fig-2) and END CAP(fig-3) are joind/locked together. SPRING(fig-5) is
placed inside the PUSHER CHAMBER HOUSING and PUSHER SPINDLE WITH
NEEDLE (fig-4) moves through all these parts of my DRY POWDER INHALER DEVICE.
The CAPSULE CHAMBER FRONT NOZZLE and PUSHER CHAMBER HOUSING
give shape to a capsule chamber when both these are joined/locked together. In this
capsule chamber dry powder capsule is installed for inhalation purpose.
SPRING is placed inside the hollow place of PUSHER CHAMBER HOUSING. PUSHER
SPINDLE WITH NEEDLE is placed and moves through all parts of my DRY POWDER
INHALER DEVICE. The hind portion of PUSHER SPINDLE WITH NEEDLE will always
remain out of device,
but the front portion of PUSHER SPINDLE WITH NEEDLE never come out from
CAPSULE CHAMBER FRONT NOZZLE front portion. The inhalation procedure is very
simple through my device. Only three steps are required to inhale the drug from my DRY
POWDER INHALER DEVICE.. 1. FILL CAPSULE IN THE CAPSULE CHAMBER. 2. PUSH
AND RELEASE THE BACK SIDE OF THE PUSHER SPINDLE WITH NEEDLE. 3. INHALE
THE DRUG POWDER FROM THE FRONT OF CAPSULE CHAMBER FRONT NOZZLE.
Fig. 7 of accomapnying drawings for over all view and Fig. 1 to 5 other drawings for five
respective parts of my DRY POWDER INHALER DEVICE.
Page no.7
I CLAIM
1. A DRY POWDER INHALER DEVICE comprising of CAPSULE CHAMBER FRONT NOZZLE, PUSHER
CHAMBER HOUSING, PUSHER SPINDLE WITH NEEDLE, SPRING and END CAP for DRY
POWDER INHALER DEVICE for Asthma, Chronic Obstructive Pulmonary Disease (COPD) and
other patients who require DRY POWDER DRUGS through inhalation.
2. A Device as claimed in claim no.l, where in a CAPSULE CHAMBER FRONT NOZZLE, which is a
hollow structure with special characteristics like a "half capsule chamber", "inhalation
mouth" and "threaded hind portion". The threaded hind portion is for joining /setting with
PUSHER CHAMBER HOUSING. Front inside portion of PUSHER CHAMBER HOUSING has a half
capsule chamber and the outer part of the front portion is threaded. Theses threaded
portions are for joining the CAPSULE CHAMBER FRONT NOZZLE with PUSHER CHAMBER
HOUSING, after which a full capsule chambers forms. In this capsule chamber a DRY
POWDER capsule is kept for inhalation purpose for patients. The body of PUSHER CHAMBER
HOUSING is hollow and may have two or more holes around. These holes are used as air
passages. The hind portion of PUSHER CHAMBER HOUSING is threaded to get joined/locked
to the threaded portion of END CAP. A PUSHER SPINDLE WITH NEEDLE is placed inside the
PUSHER CHAMBER HOUSING to pierce the installed DRY POWDER CAPSULE. The PUSHER
SPINDLE WITH NEEDLE is placed through a SPRING inside the PUSHER CHAMBER HOUSING.
The SPRING keeps the PUSHER SPINDLE WITH NEEDLE in its normal position after each push
on the back of the PUSHER SPINDLE WITH NEEDLE. The END CAP is fitted/locked to the
threaded hind portion of PUSHER CHAMBER HOUSING. The END CAP is a hollow structure
and has a hole in the middle, through which the pushing end/portion of PUSHER SPINDLE
WITH NEEDLE MOVES.
3. A DEVICE as claimed in claim no.l & 2 , where in the DEVICE adapted / configured to hold
DRY POWDER INHALER capsule inside the CAPSULE CHAMBER and where in , the two poles
of the installed capsule are pierced by PUSHER SPINDLE WITH NEEDLE through a push on the
top of back portion of PUSHER SPINDLE WITH NEEDLE.
4. A DEVICE as claimed in claim no.l, 2, 3, where in the DEVICE is made up of five parts. The
DEVICE is an easily maneuverable DRY POWDER INHALER DEVICE.
5. A DEVICE as claimed in claim no. 1-4, where in the PUSHER SPINDLE WITH NEEDLE can be
made up of single part or two parts.
Page no. 9
6. A DEVICE as claimed in claim no.1-5, where in the materials which can be used to
manufacture the DEVICE can be of surgical/medical grade POLY CARBON and surgical grade
steel or metals.
7. A DEVICE as claimed in claim no. 1-6, where in an installed DRY POWDER CAPSULE in
CAPSULE CHAMBER of my DEVICE can be pierced and Dry Powder can be inhaled by making
a small change of PUSHER CHAMBER HOUSING and PUSHER SPINDLE WITH NEEDLE. In the
body of PUSHER CHAMBER HOUSING an open channel with an extended part in one side of
the channel. The hind portion of PUSHER SPINDLE WITH NEEDLE can be given V shape and
the vertical portion of PUSHER SPINDLE WITH NEEDLE can be placed through the channel of
PUSHER CHAMBER HOUSING. The DEVICE can have same type of functional/operational
activity by a pull instead of push.
8. A DEVICE as claimed in claim no. 1-7, where in an installed DRY POWDER CAPSULE in the
CAPSULE CHAMBER of my DRY POWDER INHALER DEVICE can be pierced and DRY POWDER
can be inhaled by making a small change in design. The different design on same technique
can be done by making a small change i.e. the inside of PUSHER CHAMBER HOUSING and on
the outer portion of PUSHER SPINDLE WITH NEEDLE will threaded and there will be a wheel
like round structure on the hind top of PUSHER SPINDLE WITH NEEDLE. By rotating the
wheel like structure the installed DRY POWDER CAPSULE in the CAPSULE CHAMBER can be
pierced and DRY POWDER can be inhaled through the same technique.
9. A DEVICE as claimed in claim no. 1-8, as described wherein the description and
accompanying drawings.
Date-17.02.2006 (KAKALISENGUPTA)
Page no. 10

The invention is a DRY POWDER INHALER DEVICE. The device is a capsule based single
dose reusable DRY POWDER INHALER DEVICE. My "DRY POWDER INHALER DEVICE" is made
for those patients, who are suffering from ASTHMA, COPD or any kind of diseases, where
drug powder should be inhaled. My DRY POWDER INHALER DEVICE has five parts. A).
CAPSULE CHAMBER FRONT NOZZLE (fig-1). B) PUSHER CHAMBER HOUSING (fig-2). C).
SPRING(fig-5 ) . D). PUSHER SPINDLE WITH NEEDLE (fig-4 ). E). END CAP(fig-3).
The PUSHER SPINDLE WITH NEEDLE can be a single part of my device or may be
made of two parts i.e. needle and pusher spindle. My device can be made of four parts
also i.e. the END CAP may be the extended part of PUSHER CHAMBER HOUSING. My
device can be made up of medical grade POLY CARBON or medical grade STEEL. My
DRY POWDER INHALER DEVICE has a CAPSULE CHAMBER, Which takes shape as a
capsule chamber when CAPSULE CHAMBER FRONT NOZZLE(fig-1) and PUSHER
CHAMBER HOUSING(fig-2) are joined/locked together. Both CAPSULE CHAMBER
FRONT NOZZLE and PUSHER CHAMBER HOUSING are having half of capsule chamber.
PUSHER CHAMBER HOUSING is a hollow part of my device and has half capsule
chamber shape place to it's front side with a threaded outer body front side. The
PUSHER CHAMBER HOUSING has a small hole in the middle of halt capsule chamber
for the movement of PUSHER SPINDLE WITH NEEDLE (fig-4) by which the poles of
installed dry powder capsule's two poles can be pierced. The hind part of PUSHER
CHAMBER HOUSING is threaded, by which it can be locked/joined to END CAP. The
END CAP(fig-3) is threaded in it's front side, by which it can be loked/joined to the
PUSHER CHAMBER HOUSING. The END CAP has a hole in the middle portion of it's
back. through which the back portion of PUSHER SPINDLE WITH NEEDLE moves when
the pressure is applied. The DEVICE may be of different shapes and sizes but the
technology usued behind it is the same.

Documents:

00144-kol-2006-abstract.pdf

00144-kol-2006-claims.pdf

00144-kol-2006-description complete.pdf

00144-kol-2006-drawings.pdf

00144-kol-2006-form 1.pdf

00144-kol-2006-form 2.pdf

144-KOL-2006-ABSTRACT.pdf

144-KOL-2006-CANCELLED PAGES.pdf

144-KOL-2006-CLAIMS.pdf

144-KOL-2006-DESCRIPTION (COMPLETE).pdf

144-KOL-2006-DRAWINGS.pdf

144-kol-2006-examination report.pdf

144-KOL-2006-FORM 1.pdf

144-kol-2006-form 18.pdf

144-KOL-2006-FORM 2.pdf

144-KOL-2006-FORM 3.pdf

144-kol-2006-granted-abstract.pdf

144-kol-2006-granted-claims.pdf

144-kol-2006-granted-description (complete).pdf

144-kol-2006-granted-drawings.pdf

144-kol-2006-granted-form 1.pdf

144-kol-2006-granted-form 2.pdf

144-kol-2006-granted-specification.pdf

144-kol-2006-reply to examination report.pdf


Patent Number 243398
Indian Patent Application Number 144/KOL/2006
PG Journal Number 42/2010
Publication Date 15-Oct-2010
Grant Date 13-Oct-2010
Date of Filing 17-Feb-2006
Name of Patentee KAKALI SENGUPTA
Applicant Address MILAN PARK, MANIKPUR, KOLKATA-700079, P.O. ITALGACHA, P.S. DUMDUM, 24 PGS (N)
Inventors:
# Inventor's Name Inventor's Address
1 KAKALI SENGUPTA MILAN PARK, MANIKPUR, KOLKATA-700079, P.O. ITALGACHA, P.S. DUMDUM, 24 PGS (N)
PCT International Classification Number A61M 15/00
PCT International Application Number N/A
PCT International Filing date
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 NA