Title of Invention

CIS-2,4,5-TRIARYL-IMIDAZOLINES

Abstract CIS-2,4,5-TRIARYL-IMIDAZOLINES The present invention provides compounds according to formula (I) having the designation provided herein, and pharmaceutically acceptable salts and ester thereof. These compounds inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity.
Full Text

Documents:

3409-chenp-2005 abstract.pdf

3409-chenp-2005 claims.pdf

3409-CHENP-2005 CORRESPONDENCE OTHERS.pdf

3409-CHENP-2005 CORRESPONDENCE PO.pdf

3409-chenp-2005 correspondence-others.pdf

3409-chenp-2005 correspondence-po.pdf

3409-CHENP-2005 DESCRIPTION (COMPLETE).pdf

3409-chenp-2005 description(complete).pdf

3409-CHENP-2005 FORM 1.pdf

3409-CHENP-2005 FORM 18.pdf

3409-CHENP-2005 FORM 3.pdf

3409-CHENP-2005 FORM 5.pdf

3409-chenp-2005 form-1.pdf

3409-chenp-2005 form-18.pdf

3409-chenp-2005 form-3.pdf

3409-chenp-2005 form-5.pdf

3409-chenp-2005 others.pdf

3409-chenp-2005 pct.pdf

3409-CHENP-2005 PETITIONS.pdf

3409-CHENP-2005 POWER OF ATTORNEY.pdf

3409-chenp-2005.jpg

abs-3409-chenp-2005.jpg


Patent Number 235240
Indian Patent Application Number 3409/CHENP/2005
PG Journal Number 29/2009
Publication Date 17-Jul-2009
Grant Date 29-Jun-2009
Date of Filing 15-Dec-2005
Name of Patentee F. HOFFMANN-LA ROCHE AG
Applicant Address Grenzacherstrasse 124, CH-4070 Basel
Inventors:
# Inventor's Name Inventor's Address
1 HALEY, Gregory, Jay 13121 Ireland Lane, San Diego, California 92129
2 KONG, Norman 12 Klimback Court, West Caldwell, NJ 07006
3 LIU, Emily, Aijun 3133 Frontera Way, Unit 221, Burlingame, California 94010
4 SIMONSEN, Klaus, B. LAESSOEGADE 75, DK-5230 ODENSE
5 VU, Binh, Thanh 1 Willow Lane, North Caldwell, NJ 07006
6 VU, Binh, Thanh 1 Willow Lane, North Caldwell, NJ 07006
7 WEBBER, Stephen, Evan 3531 Millikin Avenue, San Diego, CA 92122 (US).
PCT International Classification Number C07D233/22
PCT International Application Number PCT/EP2004/006176
PCT International Filing date 2004-06-08
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 60/479,351 2003-06-17 U.S.A.