| Title of Invention | COMPOSITION AS INFLUENZA THERAPEUTIC |
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| Abstract | The present invention provides methods and compositions for inhibiting influenza infection and/or replication based on the phenomenon of RNA interference (RNAi) well as systems for identifying effective siRNAs and shRNAs for inhibiting influenza virus and systems for studying influenza virus infective mechanisms. The invention also provides methods and compositions for inhibiting infection, pathogenicity and/or replication of other infectious agents, particularly those that infect cells that are directly accessible from outside the body, e.g., skin cells or mucosal cells. In addition, the invention provides compositions comprising an RNAi-inducing entity, e.g., an siRNA, shRNA, or RNAi-inducing vector targeted to an influenza virus transcript and any of a variety of delivery agents. The invention further includes methods of use of the compositions for treatment of influenza. |
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753-KOLNP-2005-CORRESPONDENCE.pdf
753-kolnp-2005-granted-abstract.pdf
753-kolnp-2005-granted-assignment.pdf
753-kolnp-2005-granted-claims.pdf
753-kolnp-2005-granted-correspondence.pdf
753-kolnp-2005-granted-description (complete).pdf
753-kolnp-2005-granted-drawings.pdf
753-kolnp-2005-granted-examination report.pdf
753-kolnp-2005-granted-form 1.pdf
753-kolnp-2005-granted-form 13.pdf
753-kolnp-2005-granted-form 18.pdf
753-kolnp-2005-granted-form 3.pdf
753-kolnp-2005-granted-form 5.pdf
753-kolnp-2005-granted-gpa.pdf
753-kolnp-2005-granted-reply to examination report.pdf
753-kolnp-2005-granted-specification.pdf
| Patent Number | 230210 | ||||||||||||
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| Indian Patent Application Number | 753/KOLNP/2005 | ||||||||||||
| PG Journal Number | 09/2009 | ||||||||||||
| Publication Date | 27-Feb-2009 | ||||||||||||
| Grant Date | 25-Feb-2009 | ||||||||||||
| Date of Filing | 28-Apr-2005 | ||||||||||||
| Name of Patentee | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | ||||||||||||
| Applicant Address | FIVE CAMBRIDGE CENTER, CAMBRIDGE, MA 02142-1493 | ||||||||||||
Inventors:
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| PCT International Classification Number | A61K | ||||||||||||
| PCT International Application Number | PCT/US2003/030502 | ||||||||||||
| PCT International Filing date | 2003-09-29 | ||||||||||||
PCT Conventions:
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