Title of Invention

METHOD FOR OBTAINING DERIVATIVES OF [((PYRIDIL SUBSTITUTED) METHYL)THIO] BENZIMIDAZOLE

Abstract The method for obtaining derivatives of [[(pyridil substituted)methyl]thio]benzomidazol (I), where each of R1, R3 and R4, independently of each other, is hydrogen, an alkyl, alkoxy or fluorinated alkoxy of 1 to 6 carbon atoms, and R2 is nitro, halogen, alkoxy or halogenated alkoxy of 1 to 6 carbon atoms, or a group -OR-(CH2)n-OR8, where n is an integer between 1 and 6 and R8 represents hydrogen or an alkyl group with 1 to 6 carbon atoms, which involves (a) reacting an N-oxide of a methylpyridine with an anhydride of activated carboxylic acid or of sulfonic acid, and (b) reacting the intermediate formed in stage (a) with a corresponding mercaptobenzomidazol. The compounds (I) are useful in the synthesis of derivatives of [[(pyridil substituted)methyl]sulfinyl]benzomidazol, such as omeprazol, lansoprazol, rabeprazol or pantoprazol.
Full Text

Documents:

IN-PCT-2002-1272-KOL-CORRESPONDENCE.pdf

IN-PCT-2002-1272-KOL-FORM 27.pdf

in-pct-2002-1272-kol-granted-abstract.pdf

in-pct-2002-1272-kol-granted-claims.pdf

in-pct-2002-1272-kol-granted-correspondence.pdf

in-pct-2002-1272-kol-granted-description (complete).pdf

in-pct-2002-1272-kol-granted-examination report.pdf

in-pct-2002-1272-kol-granted-form 1.pdf

in-pct-2002-1272-kol-granted-form 18.pdf

in-pct-2002-1272-kol-granted-form 3.pdf

in-pct-2002-1272-kol-granted-form 5.pdf

in-pct-2002-1272-kol-granted-gpa.pdf

in-pct-2002-1272-kol-granted-letter patent.pdf

in-pct-2002-1272-kol-granted-priority document.pdf

in-pct-2002-1272-kol-granted-reply to examination report.pdf

in-pct-2002-1272-kol-granted-specification.pdf


Patent Number 220848
Indian Patent Application Number IN/PCT/2002/1272/KOL
PG Journal Number 23/2008
Publication Date 06-Jun-2008
Grant Date 06-Jun-2008
Date of Filing 08-Oct-2002
Name of Patentee ESTEVE QUIMICA S.A.
Applicant Address AVDA. MARE DE DEU DE MONTSERRAT, 12, E-O8024, BARCELONA
Inventors:
# Inventor's Name Inventor's Address
1 COPPI LAURA AVDA, MARE DE DEU DE MONTSERRAT, 12, E-08024, BARCELONA
2 BERENGUER MAIMO RAMON AVDA, MARE DE DEU DE MONTSERRAT, 12, E-08024, BARCELONA
PCT International Classification Number C07D 401/12
PCT International Application Number PCT/ES01/00143
PCT International Filing date 2001-04-10
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 P200000989 2000-04-14 Spain