Title of Invention

HUMAN PAPILLOMAVIRUS POLYPEPTIDES AND IMMUNOGENIC COMPOSITIONS

Abstract The present invention provides immunogenic and pharmaceutical compositions for the treatment and prevention of human papillomavirus (HPV)-associaled cancers and in particular, cervical cancer. In particular, this invention relates to fusion proteins, and the nucleic acids encoding these fusion proteins used to generate immune responses against HPV Specifically, this invention provides Tor fusions of HPV E6 and E7 in which the E6 and/or E7 contains one or more mutations .These mulations abrogate the transformation activity of these oncogenic proteins and, thus, confer safety to the E6/E7 fusions In addition, these fusions maintain or increase the immunogenic efficacy of E6 and E7 Any gene or protein delivery method can be used to deliver or package the immunogenic compositions of the present invention.
Full Text

Documents:

00505-kolnp-2005-abstract.pdf

00505-kolnp-2005-assignment.pdf

00505-kolnp-2005-claims.pdf

00505-kolnp-2005-correspondence-1.1.pdf

00505-kolnp-2005-correspondence-1.2.pdf

00505-kolnp-2005-correspondence-1.3.pdf

00505-kolnp-2005-correspondence-1.4.pdf

00505-kolnp-2005-correspondence-1.5.pdf

00505-kolnp-2005-correspondence.pdf

00505-kolnp-2005-description(complete).pdf

00505-kolnp-2005-drawings.pdf

00505-kolnp-2005-form-1.pdf

00505-kolnp-2005-form-13.pdf

00505-kolnp-2005-form-18.pdf

00505-kolnp-2005-form-3-1.1.pdf

00505-kolnp-2005-form-3-1.2.pdf

00505-kolnp-2005-form-3-1.3.pdf

00505-kolnp-2005-form-3.pdf

00505-kolnp-2005-form-5.pdf

00505-kolnp-2005-g.p.a.pdf

00505-kolnp-2005-international publication.pdf

00505-kolnp-2005-international search authority report.pdf

00505-kolnp-2005-others document.pdf

00505-kolnp-2005-pct others.pdf

00505-kolnp-2005-priority document.pdf

505-KOLNP-2005-(29-11-2005)-CORRESPONDENCE.pdf

505-KOLNP-2005-(29-11-2005)-PA.pdf

505-KOLNP-2005-CORRESPONDENCE 1.5.pdf

505-KOLNP-2005-FORM-27.pdf

505-kolnp-2005-granted-abstract.pdf

505-kolnp-2005-granted-assignment.pdf

505-kolnp-2005-granted-claims.pdf

505-kolnp-2005-granted-correspondence.pdf

505-kolnp-2005-granted-description (complete).pdf

505-kolnp-2005-granted-drawings.pdf

505-kolnp-2005-granted-examination report.pdf

505-kolnp-2005-granted-form 1.pdf

505-kolnp-2005-granted-form 13.pdf

505-kolnp-2005-granted-form 18.pdf

505-kolnp-2005-granted-form 3.pdf

505-kolnp-2005-granted-form 5.pdf

505-kolnp-2005-granted-gpa.pdf

505-kolnp-2005-granted-letter patent.pdf

505-kolnp-2005-granted-reply to examination report.pdf

505-kolnp-2005-granted-sequence listing.pdf

505-kolnp-2005-granted-specification.pdf

505-KOLNP-2005-OTHERS PATENT DOCUMENTS.pdf

505-KOLNP-2005-PA.pdf


Patent Number 220842
Indian Patent Application Number 505/KOLNP/2005
PG Journal Number 23/2008
Publication Date 06-Jun-2008
Grant Date 06-Jun-2008
Date of Filing 24-Mar-2005
Name of Patentee WYETH HOLDINGS CORPORATION
Applicant Address FIVE GIRALDA FARMS, MADISON, NJ 07940
Inventors:
# Inventor's Name Inventor's Address
1 SMITH, LARRY 11410 TURTLEBACK LANE, SAN DIEGO, CA 92127
2 CASSETTI, MARIA, CRISTINA 8217 SCOTCH BEND WAY, POTOMAC, MD 20854
3 MCELHINEY, SUSAN, P P.O. BOX 1039, HILLBURN, NY 10931
4 PULLEN, JEFFREY, K C/O WYETH RESEARCH BUILDING, 401 N. MIDDLETOW ROAD, PEARL RIVER, NY 10695
PCT International Classification Number A61K 38/00
PCT International Application Number PCT/US2003/031726
PCT International Filing date 2003-10-02
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 60/415, 929 2002-10-03 U.S.A.