Title of Invention

I"NHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3-NS4 PROTEASE"

Abstract The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds (FIG. - nil)
Full Text

Documents:

1504-kolnp-2004-granted-abstract.pdf

1504-kolnp-2004-granted-assignment.pdf

1504-kolnp-2004-granted-claims.pdf

1504-kolnp-2004-granted-correspondence.pdf

1504-kolnp-2004-granted-description (complete).pdf

1504-kolnp-2004-granted-examination report.pdf

1504-kolnp-2004-granted-form 1.pdf

1504-kolnp-2004-granted-form 13.pdf

1504-kolnp-2004-granted-form 18.pdf

1504-kolnp-2004-granted-form 3.pdf

1504-kolnp-2004-granted-form 5.pdf

1504-kolnp-2004-granted-gpa.pdf

1504-kolnp-2004-granted-letter patent.pdf

1504-kolnp-2004-granted-reply to examination report.pdf

1504-kolnp-2004-granted-specification.pdf


Patent Number 219924
Indian Patent Application Number 01504/KOLNP/2004
PG Journal Number 20/2008
Publication Date 16-May-2008
Grant Date 14-May-2008
Date of Filing 08-Oct-2004
Name of Patentee VERTEX PHARMACEUTICAL INCORPORATED
Applicant Address 130, WAVERLY STREET CAMBRIDGE USA.
Inventors:
# Inventor's Name Inventor's Address
1 PITLIK JANOS 1 ROBIN CIRCLE WESTBOROUGH USA.
2 COTTRELL KEVIN M 54 PEARL STREET #3 CAMBRIDE USA
3 FARMER LUC J 19 HOWE LANE FOXBORO USA.
4 PERNI ROBERT B 130 ROBERT ROAD MARLBOROUH USA.
5 COURTNEY LAWARENCE F 5-5 KINGSON WAY MEDWAY USA.
6 VAN DRIE JOHN H 34 STINSON ROAD ANDOVER USA
7 MURCKO MARK A 520 MARSHALL STREET HOLLISTON USA.
PCT International Classification Number C07D403/12
PCT International Application Number PCT/US2003/011459
PCT International Filing date 2003-04-11
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 60/371, 846 2002-04-11 U.S.A.