| Title of Invention | 3- AMNOPY RROLIDINE COMPOUNDS |
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| Abstract | The present invention relates to 3-aminopyrrolidine derivatives of the formula I: X~Y /Z I (wherein R1, R2, R3, R4, R5, R6, R7, R8, X, Y and X are as defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of chemokine receptors and more specifically as a modulator of the CCR2 and/or CCR5 receptor. The compounds and compositions of the invention may bind to chemokine receptors, e.g., the CCR2 and/or CCR5 chemokine receptors, and are useful for treating diseases associated with chemokine, e.g., CCR2 and/or CCR5, activity, such as atherosclerosis, restenosis, lupus, organ transplant rejection and rheumatoid arthritis. |
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01051-kolnp-2005-description complete.pdf
01051-kolnp-2005-international publication.pdf
1051-kolnp-2005-granted-abstract.pdf
1051-kolnp-2005-granted-assignment.pdf
1051-kolnp-2005-granted-claims.pdf
1051-kolnp-2005-granted-correspondence.pdf
1051-kolnp-2005-granted-description (complete).pdf
1051-kolnp-2005-granted-examination report.pdf
1051-kolnp-2005-granted-form 1.pdf
1051-kolnp-2005-granted-form 18.pdf
1051-kolnp-2005-granted-form 3.pdf
1051-kolnp-2005-granted-form 5.pdf
1051-kolnp-2005-granted-gpa.pdf
1051-kolnp-2005-granted-letter patent.pdf
1051-kolnp-2005-granted-reply to examination report.pdf
1051-kolnp-2005-granted-specification.pdf
| Patent Number | 219919 | |||||||||||||||||||||||||||
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| Indian Patent Application Number | 01051/KOLNP/2005 | |||||||||||||||||||||||||||
| PG Journal Number | 20/2008 | |||||||||||||||||||||||||||
| Publication Date | 16-May-2008 | |||||||||||||||||||||||||||
| Grant Date | 14-May-2008 | |||||||||||||||||||||||||||
| Date of Filing | 02-Jun-2005 | |||||||||||||||||||||||||||
| Name of Patentee | INCYTE CORPORATION | |||||||||||||||||||||||||||
| Applicant Address | 3160 PORTER DRIVE, PALO ALTO, CA 94304, U.S.A | |||||||||||||||||||||||||||
Inventors:
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| PCT International Classification Number | A61K | |||||||||||||||||||||||||||
| PCT International Application Number | PCT/US2003/037946 | |||||||||||||||||||||||||||
| PCT International Filing date | 2003-11-26 | |||||||||||||||||||||||||||
PCT Conventions:
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