| Title of Invention | " AN ANTI-OSTEOPONTIN ANTIBODY OR AN ANTIBODY FRAGMENT DERIVED THEREFROM" |
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| Abstract | A recombinant antibody in which at least the constant regions in the heavy chain and the light chain have been converted into human-origin regions and which inhibits the binding of an integrin recognizing the RGD sequence to osteopontin or its fragment and inhibits the binding of an integrin recognizing the SVVYGLR sequence or a sequence corresponding thereto to osteopontin or its fragment. This antibody is useful as a remedy for autoimmune diseases and a remedy for rheumatism or rheumatoid arthritis. Thus, a method of treating autoimmune diseases, rheumatism or rheumatoid arthritis is provided. This osteopontin antibody is useful in a diagnostic for rheumatism and a method of diagnosing rheumatism too. (FIG. -) |
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359-kolnp-2004-granted-abstract.pdf
359-kolnp-2004-granted-assignment.pdf
359-kolnp-2004-granted-claims.pdf
359-kolnp-2004-granted-description (complete).pdf
359-kolnp-2004-granted-drawings.pdf
359-kolnp-2004-granted-examination report.pdf
359-kolnp-2004-granted-form 1.pdf
359-kolnp-2004-granted-form 13.pdf
359-kolnp-2004-granted-form 18.pdf
359-kolnp-2004-granted-form 3.pdf
359-kolnp-2004-granted-form 5.pdf
359-kolnp-2004-granted-form 6.pdf
359-kolnp-2004-granted-gpa.pdf
359-kolnp-2004-granted-letter patent.pdf
359-kolnp-2004-granted-reply to examination report.pdf
359-kolnp-2004-granted-sequence listing.pdf
359-kolnp-2004-granted-specification.pdf
359-kolnp-2004-granted-translated copy of priority document.pdf
| Patent Number | 219898 | |||||||||||||||||||||||||||
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| Indian Patent Application Number | 00359/KOLNP/2004 | |||||||||||||||||||||||||||
| PG Journal Number | 20/2008 | |||||||||||||||||||||||||||
| Publication Date | 16-May-2008 | |||||||||||||||||||||||||||
| Grant Date | 14-May-2008 | |||||||||||||||||||||||||||
| Date of Filing | 17-Mar-2004 | |||||||||||||||||||||||||||
| Name of Patentee | IMMUNO-BIOLOGICAL LABORATORIES CO. LTD. AND FUJISAWA PHARMACEUTICAL CO., LTD. | |||||||||||||||||||||||||||
| Applicant Address | 1091-1, NAKA AA HIGASHIDA, FUJIOKA-SHI , GUNMA- JAPAN | |||||||||||||||||||||||||||
Inventors:
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| PCT International Classification Number | C07K16/18 | |||||||||||||||||||||||||||
| PCT International Application Number | PCT/JP02/09868 | |||||||||||||||||||||||||||
| PCT International Filing date | 2002-09-25 | |||||||||||||||||||||||||||
PCT Conventions:
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