| Title of Invention | PARICLES COATED WITH GRANULATED CRYSTALLINE IBUPROFEN |
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| Abstract | The invention concerns coated particles based on granulated microcystals of ibuprofen, its pharmaceutically acceptable isomers and salts, characterised in that they comprise a coating obtained in a fluidised bed apparatus with a hydroalcoholic dispersion consisting of a mixture comprising : A) 5 to 50wt% of ethylcellulose relative to ibuprofen; B) 10 to 60wt.% of hydroxypeoplylmethylcellulose relative to the ethylcellulose; and C)0.1 to 40 wt.% of silica with antistatic and permeabilising properties relative to the ethylcellulose; the resulting coating, whereof at least one of the constituents can be used for granulating the ibuprofen microcrystals resulting in said particles, thereby masking the unpleasant taste of ibuprofen and significantly reducing its irritating effect on the throat after deglutition and substantially immediate release of ibuprofen when the particles are placed in an aqueous medium. |
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in-pct-2001-00453-kol-granted-abstract.pdf
in-pct-2001-00453-kol-granted-claims.pdf
in-pct-2001-00453-kol-granted-correspondence.pdf
in-pct-2001-00453-kol-granted-description (complete).pdf
in-pct-2001-00453-kol-granted-form 1.pdf
in-pct-2001-00453-kol-granted-form 18.pdf
in-pct-2001-00453-kol-granted-form 2.pdf
in-pct-2001-00453-kol-granted-form 3.pdf
in-pct-2001-00453-kol-granted-form 5.pdf
in-pct-2001-00453-kol-granted-form 6.pdf
in-pct-2001-00453-kol-granted-letter patent.pdf
in-pct-2001-00453-kol-granted-pa.pdf
in-pct-2001-00453-kol-granted-priority document.pdf
in-pct-2001-00453-kol-granted-reply to examination report.pdf
in-pct-2001-00453-kol-granted-specification.pdf
in-pct-2001-00453-kol-granted-translated copy of priority document.pdf
IN-PCT-2001-453-KOL-(03-11-2011)-OTHER PATENT DOCUMENTS.pdf
IN-PCT-2001-453-KOL-CORRESPONDENCE 1.1.pdf
IN-PCT-2001-453-KOL-CORRESPONDENCE.pdf
IN-PCT-2001-453-KOL-FORM 27 1.1.pdf
IN-PCT-2001-453-KOL-FORM 27.pdf
| Patent Number | 218715 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Indian Patent Application Number | IN/PCT/2001/453/KOL | ||||||||||||
| PG Journal Number | 15/2008 | ||||||||||||
| Publication Date | 11-Apr-2008 | ||||||||||||
| Grant Date | 09-Apr-2008 | ||||||||||||
| Date of Filing | 23-Apr-2001 | ||||||||||||
| Name of Patentee | ETHYPHARM | ||||||||||||
| Applicant Address | 21, RUE SAINT MATTHIEU, 78550 HOUDAN, FRANCE. A COMPANY DULY ORGANISED AND EXISTING UNDER THE LAWS OF FRANCE. | ||||||||||||
Inventors:
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| PCT International Classification Number | a61K 9/50,31/19 | ||||||||||||
| PCT International Application Number | PCT/FR99/02682 | ||||||||||||
| PCT International Filing date | 1999-11-03 | ||||||||||||
PCT Conventions:
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