Title of Invention

COMPOSITIONS FOR CONTROLLING ANIMAL PESTS

Abstract Compositions for controlling animal pests, comprising a synergisticaUy active mixture of clothianidin of the formula (I) and at least one compound from the group consisting of abamectin, emamectin or emamectin benzoate and methiocarb, wherein the weight ratio of active compound is from 0.1 to 95%.
Full Text FORM 2
THE PATENTS ACT 1970 [39 OF 1970]
& THE PATENTS RULES, 2003 COMPLETE SPECIFICATION
[Set Section 10]
'COMPOSITIONS FOR CONTROLLING ANIMAL PESTS"
BAYER CROPSCIENCE AG, Germany of Alfred-Nobel-Str. 50, 40789 Monheim, Germany,
The following specification particularly describes the invention and the manner in which it is to be performed:

GRANTED



9-2-2007

The present invention relates to compositions for controlling animal
pests and a process thereof
The present invention relates to novel combinations of active compounds
comprising, firstly, the known active compound clothianidin and, secondly, at least
one further known insecticidally active compound, which combinations have very good insecticidal and acaricidal properties.
It is already known that clothianidin of the formula


can be used for controlling animal pests, in particular insects (cf. EP-A-376 279 and
EP 375 907). The activity of this compound is good; however, at low application
rates or against individual pests, it is sometimes unsatisfactory.
It is also known that the compounds abamectin (II) (DE 2 717 040), emamectin (III)
or emamectin benzoate (III) (EP 089 202), methiocarb (IV) (US 3,313,684), p-
cyfluthrin (V) (EP 206 149) and lambda-cyhalothrin (VI) (EP 106 469) can be used
for controlling insects and/or acarids.
It has now been found that mixtures, comprising clothianidin of the formula (I)

and at least one of the compounds (II), (III), (IIIa), (IV), (V) and (VI) are
synergistically active and suitable for controlling animal pests. Owing to this

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synergism, it is possible to use considerably smaller amounts of active compounds, i.e. the activity of the mixture is greater than the activity of the individual components.
The ratio of the compound of the formula (I) used to the compounds of the formulae
(II) to (VI), and the total amount of the mixture to be used depends on the nature and the occurrence of the insects and/or acarids. For each application, it is possible to determine the optimum ratios and total amounts to be used in each case by test series.
A preferred mixture according to the invention comprises the active compound
clothianidin of the formula (I) and abamectin (II). Abamectin is also known from "The Pesticide Manual", 11th Edition, British Crop Protection Council, 1997, page 3.
In this mixture, the ratio of the active compounds can be varied within a relatively
wide range. The weight ratio of clothianidin to abamectin is preferably from 1:1 to
50:1, in particular from 5:1 to 25:1.
A further preferred mixture according to the invention comprises the active
compound clothianidin of the formula (I) and emamectin (III) or emamectin benzoate
(IIIa). Emamectin and emamectin salts are also known as MK-244 from the Journal
of Organic Chemistry, Vol. 59 (1994), 7704-7708, US-P-4,4874,794, US-P-5,5,288,710 and EP-00 089 202.
In this mixture, the ratio of the active compounds can be varied within a relatively
wide range. The weight ratio of clothianidin to emamectin or emamectin benzoate is
preferably from 1:1 to 500:1, in particular from 100:1 to 500:1.
A further preferred mixture according to the invention comprises the active
compound clothianidin of the formula (I) and methiocarb (IV). Methiocarb (TV) is
also known from "The Pesticide Manual", 11 Edition, British Crop Protection
Council, 1997, page 813.

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In this mixture, the ratio of the active compounds can be varied within a relatively wide range. The weight ratio of clothianidin to methiocarb is preferably from 1:1 to 1:10, in particular from 1:1 to 1:5.
A further preferred mixture according to the invention comprises the active compound clothianidin of the formula (I) and (3-cyfluthrin (V). (3-cyfluthrin is also known from "The Pesticide Manual", 11th Edition, British Crop Protection Council, 1997, page 295.
In this mixture, the ratio of the active compounds can be varied within a relatively wide range. The weight ratio of clothianidin to (3-cyfluthrin is preferably from 1:1 and 10:1, in particular from 1:1 to 6:1.

A further preferred mixture according to the invention comprises the active
compound clothianidin of the formula (I) and lambda-cyhalothrin (VI). Lambda-cyhalothrin (VI) is also known from "The Pesticide Manual", 11th Edition, British Crop Protection Council, 1997, page 300.
In this mixture, the ratio of the active compounds can be varied within a relatively
wide range. The weight ratio of clothianidin to lambda-cyhalothrin is preferably from 1:1 to 10:1, in particular from 1:1 to 6:1.
The active compound combinations are suitable for controlling animal pests, in
particular insects, arachnids and nematodes, which are encountered in agriculture, in
forestry, in the protection of stored products and of materials, and in the hygiene sector,
and have good plant tolerance and favourable toxicity to warm-blooded animals. They
may be preferably employed as crop protection agents. They are active against
normally sensitive and resistant species and against all or some stages of development.
The abovementioned pests include:


Accordingly there is provided compositions for controlling animal pests, comprising a synergistically active mixture of clothianidin of the formula (I)

and at least one compound from the group consisting of abamectin, emamectin or emamectin benzoate and methiocarb.

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From the order of the Isopoda, for example, Oniscus asellus, Armadillidium vulgare and Porcellio scaber.
From the order of the Diplopoda, for example, Blaniulus guttulatus.
From the order of the Chilopoda, for example, Geophilus carpophagus and Scutigera spp.
ID
From the order of the Symphyla, for example, Scutigerella immaculata.
From the order of the Thysanura, for example, Lepisma saccharina.
From the order of the Collembola, for example, Onychiurus armatus.
From the order of the Orthoptera, for example, Acheta domesticus, Gryllotalpa spp.,
Locusta migratoria migratorioides, Melanoplus spp. and Schistocerca gregaria.
From the order of the Blattaria, for example, Blatta orientalis, Periplaneta americana, Leucophaea maderae, Blattella germanica.
From the order of the Dermaptera, for example, Forficula auricularia.
From the order of the Isoptera, for example, Reticulitermes spp.
From the order of the Phthiraptera, for example, Pediculus humanus corporis,
Haematopinus spp., Linognathus spp., Trichodectes spp. and Damalinia spp.
From the order of the Thysanoptera, for example, Hercinothrips femoralis, Thrips tabaci, Thrips palmi and Frankliniella occidentalis.

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From the order of the Heteroptera, for example, Eurygaster spp., Dysdercus intermedius, Piesma quadrata, Cimex lectularius, Rhodnius prolixus and Triatoma spp.
From the order of the Homoptera, for example, Aleurodes brassicae, Bemisia tabaci,
Trialeurodes vaporariorum, Aphis gossypii, Brevicoryne brassicae, Cryptomyzus ribis,
Aphis fabae, Aphis pomi, Eriosoma lanigerum, Hyalopterus arundinis, Phylloxera
vastatrix, Pemphigus spp., Macrosiphum avenae, Myzus spp., Phorodon humuli,
Rhopalosiphum padi, Empoasca spp., Euscelis bilobatus, Nephotettix cincticeps,
Lecanium corni, Saissetia oleae, Laodelphax striatellus, Nilaparvata lugens, Aonidiella
aurantii, Aspidiotus hederae, Pseudococcus spp. and Psylla spp.
From the order of the Lepidoptera, for example, Pectinophora gossypiella, Bupalus piniarius, Cheimatobia brumata, Lithocolletis blancardella, Hyponomeuta padella, Plutella xylostella, Malacosoma neustria, Euproctis chrysorrhoea, Lymantria spp.,
Bucculatrix thurberiella, Phyllocnistis citrella, Agrotis spp., Euxoa spp., Feltia spp.,
Earias insulana, Heliothis spp., Mamestra brassicae, Panolis flammea, Spodoptera spp., Trichoplusia ni, Carpocapsa pomonella, Pieris spp., Chilo spp., Pyrausta nubilalis, Ephestia kuehniella, Galleria mellonella, Tineola bisselliella, Tinea pellionella, Hofmannophila pseudospretella, Cacoecia podana, Capua reticulana, Choristoneura
fumiferana, Clysia ambiguella, Homona magnanima, Tortrix viridana, Cnaphalocerus
spp. and Oulema oryzae.
From the order of the Coleoptera, for example, Anobium punctatum, Rhizopertha dominica, Bruchidius obtectus, Acanthoscelides obtectus, Hylotrupes bajulus,
Agelastica alni, Leptinotarsa decemlineata, Phaedon cochleariae, Diabrotica spp.,
Psylliodes chrysocephala, Epilachna varivestis, Atomaria spp., Oryzaephilus surinamensis, Anthonomus spp., Sitophilus spp., Otiorrhynchus sulcatus, Cosmopolites sordidus, Ceuthorrhynchus assimilis, Hypera postica, Dermestes spp., Trogoderma spp., Anthrenus spp., Attagenus spp., Lyctus spp., Meligethes aeneus,
Ptinus spp., Niptus hololeucus, Gibbium psylloides, Tribolium spp., Tenebrio molitor,




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Agriotes spp., Conoderus spp., Melolontha melolontha, Amphimallon solstitialis, Costelytra zealandica and Lissorhoptrus oryzophilus.
From the order of the Hymenoptera, for example, Diprion spp., Hoplocampa spp., Lasius spp., Monomorium pharaonis and Vespa spp.
From the order of the Diptera, for example, Aedes spp., Anopheles spp., Culex spp., Drosophila melanogaster, Musca spp., Fannia spp., Calliphora erythrocephala, Lucilia spp., Chrysomyia spp., Cuterebra spp., Gastrophilus spp., Hyppobosca spp., Stomoxys spp., Oestrus spp., Hypoderma spp., Tabanus spp., Tannia spp., Bibio hortulanus, Oscinella frit, Phorbia spp., Pegomyia hyoscyami, Ceratitis capitata, Dacus oleae, Tipula paludosa, Hylemyia spp. and Liriomyza spp.
From the order of the Siphonaptera, for example, Xenopsylla cheopis and
Ceratophyllus spp.
From the class of the Arachnida, for example, Scorpio maurus, Latrodectus mactans,
Acarus siro, Argas spp., Ornithodoros spp., Dermanyssus gallinae, Eriophyes ribis,
Phyllocoptruta oleivora, Boophilus spp., Rhipicephalus spp., Amblyomma spp.,
Hyalomma spp., Ixodes spp., Psoroptes spp., Chorioptes spp., Sarcoptes spp.,
Tarsonemus spp., Bryobia praetiosa, Panonychus spp., Tetranychus spp., Hemitarsonemus spp., and Brevipalpus spp.
The phytoparasitic nematodes include, for example, Pratylenchus spp., Radopholus
similis, Ditylenchus dipsaci, Tylenchulus semipenetrans, Heterodera spp., Globodera
spp., Meloidogyne spp., Aphelenchoides spp., Longidorus spp., Xiphinema spp., Trichodorus spp. and Bursaphelenchus spp.
According to the invention, it is possible to treat all plants and parts of plants. By
plants are to be understood here all plants and plant populations such as desired and
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plants can be plants which can be obtained by conventional breeding and
optimization methods or by biotechnological and genetic engineering methods or
combinations of these methods, including the transgenic plants and including plant
cultivars which can or cannot be protected by plant breeders, rights. Parts of plants
are to be understood as meaning all above-ground and below-ground parts and
organs of plants, such as shoot, leaf, flower and root, examples which may be
mentioned being leaves, needles, stems, trunks, flowers, shoot-bodies, fruits and
seeds and also roots, tubers and rhizomes. Parts of plants also include harvested
plants and vegetative and generative propagation material, for example seedlings,
tubers, rhizomes, cuttings and seeds.
The treatment of the plants and parts of plants according to the invention with the
active compound combinations is carried out directly or by action on their
environment, habitat or storage area according to customary treatment methods, for
example by dipping, spraying, evaporating, atomizing, broadcasting, brushing-on
and, in the case of propagation material, in particular in the case of seeds, furthermore by one- or multi-layer coating.
The active compound combinations can be converted to the customary formulations,
such as solutions, emulsions, wettable powders, suspensions, powders, dusts, pastes,
soluble powders, granules, suspension-emulsion concentrates, natural and synthetic materials impregnated with active compound and microencapsulations in polymeric substances.
These formulations are produced in a known manner, for example by mixing the active
compounds with extenders, that is liquid solvents and/or solid carriers, optionally with the use of surfactants, that is emulsifiers and/or dispersants and/or foam-formers.
If the extender used is water, it is also possible to employ for example organic solvents as auxiliary solvents. Essentially, suitable liquid solvents are: aromatics such as xylene, toluene or alkylnaphthalenes, chlorinated aromatics or chlorinated aliphatic

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hydrocarbons such as chlorobenzenes, chloroethylenes or methylene chloride, aliphatic
hydrocarbons such as cyclohexane or paraffins, for example petroleum fractions,
mineral and vegetable oils, alcohols such as butanol or glycol and also their ethers and
esters, ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or
cyclohexanone, strongly polar solvents such as dimethylformamide and dimethyl
sulphoxide, and also water.
Suitable solid carriers are:
for example ammonium salts and ground natural minerals such as kaolins, clays, talc,
chalk, quartz, attapulgite, montmorillonite or diatomaceous earth, and ground synthetic minerals, such as highly disperse silica, alumina and silicates; suitable solid carriers for granules are: for example crushed and fractionated natural rocks such as calcite, marble, pumice, sepiolite and dolomite, and also synthetic granules of inorganic and organic meals, and granules of organic material such as sawdust, coconut shells, maize cobs and tobacco stalks; suitable emulsifiers and/or foam-formers are: for example nonionic and anionic emulsifiers, such as polyoxyethylene fatty acid esters, polyoxyethylene fatty alcohol ethers, for example alkylaryl polyglycol ethers, alkylsulphonates, alkyl sulphates, arylsulphonates and also protein hydrolysates; suitable dispersants are: for example lignosulphite waste liquors and methylcellulose.
Tackifiers such as carboxymethylcellulose and natural and synthetic polymers in the form of powders, granules or latices, such as gum arabic, polyvinyl alcohol and polyvinyl acetate, as well as natural phospholipids such as cephalins and lecithins, and synthetic phospholipids, can be used in the formulations. Possible other additives are mineral and vegetable oils.
It is possible to use colorants such as inorganic pigments, for example iron oxide,
titanium oxide and Prussian Blue, and organic dyestuffs, such as alizarin dyestuffs, azo
dyestuffs and metal phthalocyanine dyestuffs, and trace nutrients such as salts of iron,
manganese, boron, copper, cobalt, molybdenum and zinc.

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The formulations generally comprise between 0.1 and 95% by weight of active compound, preferably between 0.5 and 90%.
The active compound combinations according to the invention can be present in commercially available formulations and in the use forms, prepared from these formulations, as a mixture with other active compounds, such as insecticides, attractants, sterilizing agents, bactericides, acaricides, nematicides, fungicides, growth-regulating substances or herbicides. The insecticides include, for example, phosphoric acid esters, carbamates, carboxylates, chlorinated hydrocarbons, phenylureas and substances produced by microorganisms, inter alia.
Particularly favourable examples of co-components in mixtures are the following compounds:
Fungicides:
aldimorph, ampropylfos, ampropylfos potassium, andoprim, anilazine, azaconazole,
azoxystrobin,
benalaxyl, benodanil, benomyl, benzamacril, benzamacryl-isobutyl, bialaphos, binapacryl, biphenyl, bitertanol, blasticidin-S, bromuconazole, bupirimate, buthiobate,
calcium polysulphide, capsimycin, captafol, captan, carbendazim, carboxin, carvon,
quinomethionate, chlobenthiazone, chlorfenazole, chloroneb, chloropicrin, chlorothalonil, chlozolinate, clozylacon, cufraneb, cymoxanil, cyproconazole, cyprodinil, cyprofuram,
debacarb, dichlorophen, diclobutrazole, diclofluanid, diclomezine, dicloran,
diethofencarb, difenoconazole, dimethirimol, dimethomorph, diniconazole,

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diniconazole-M, dinocap, diphenylamine, dipyrithione, ditalimfos, dithianon, dodemorph, dodine, drazoxolon,
edifenphos, epoxiconazole, etaconazole, ethirimol, etridiazole,
famoxadon, fenapanil, fenarimol, fenbuconazole, fenfuram, fenitropan, fenpiclonil,
fenpropidin, fenpropimorph, fentin acetate, fentin hydroxide, ferbam, ferimzone,
fluazinam, flumetover, fluoromide, fluquinconazole, flurprimidol, flusilazole,
flusulfamide, flutolanil, flutriafol, folpet, fosetyl-aluminium, fosetyl-sodium, fthalide,
Albendazole, furalaxyl, furametpyr, furcarbonil, furconazole, furconazole-cis,
furmecyclox,
guazatine,
hexachlorobenzene, hexaconazole, hymexazole,
imazalil, imibenconazole, iminoctadine, iminoctadine albesilate, iminoctadine triacetate, iodocarb, ipconazole, iprobenfos (IBP), iprodione, irumamycin, isoprothiolane, isovaledione,

kasugamycin, kresoxim-methyl, copper preparations, such as: copper hydroxide, copper naphthenate, copper oxychloride, copper sulphate, copper oxide, oxine-copper and Bordeaux mixture,
mancopper, mancozeb, maneb, meferimzone, mepanipyrim, mepronil, metalaxyl,
metconazole, methasulfocarb, methfuroxam, metiram, metomeclam, metsulfovax, mildiomycin, myclobutanil, myclozolin,



nickel dimethyldithiocarbamate, nitrothal-isopropyl, nuarimol, ofurace, oxadixyl, oxamocarb, oxolinic acid, oxycarboxim, oxyfenthiin,

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paclobutrazole, pefurazoate, penconazole, pencycuron, phosdiphen, pimaricin, piperalin, polyoxin, polyoxorim, probenazole, prochloraz, procymidone, propamocarb, propanosine-sodium, propiconazole, propineb, pyrazophos, pyrifenox, pyrimethanil, pyroquilon, pyroxyfur,
quinconazole, quintozene (PCNB),
sulphur and sulphur preparations,
tebuconazole, tecloftalam, tecnazene, tetcyclasis, tetraconazole, thiabendazole, thicyofen, thifluzamide, thiophanate-methyl, thiram, tioxymid, tolclofos-methyl, tolylfluanid, triadimefon, triadimenol, triazbutil, triazoxide, trichlamide, tricyclazole, tridemorph, triflumizole, triforine, triticonazole,
uniconazole,

validamycin A, vinclozolin, viniconazole,
zarilamide, zineb, ziram and also
Dagger G,
OK-8705,
OK-8801,
a-( 1,1 -dimethylethyl)-P-(2-phenoxy ethyl)-1H-1,2,4-triazole-1 -ethanol,
a-(2,4-dichlorophenyl)-P-fluoro-(3-propyl- 1H-1,2,4-triazole-1 -ethanol,
a-(2,4-dichlorophenyl)-p-methoxy-a-methyl-lH-l,2,4-triazole-l-ethanol,

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a-(5-methyl-l3-dioxan-5-yl)-(3-[[4-(1xifluoromethyl)-phenyl]-methylene]-lH-l,2,4-triazole-1-ethanol,
(5RS,6RS)-6-hydroxy-2,2,7,7-tetramethyl-5-(lH-l,2,4-triazol-l-yl)-3-octanone,
(E)-a-(methoxyimino)-N-methyl-2-phenoxy-phenylacetamide,
1 -isopropyl {2-methyl-1 -[[[1 -(4-methylphenyl)-ethyl]-amino]-carbonyl]-propyl} -carbamate,
1 -(2,4-dichlorophenyl)-2-( 1H-1,2,4-triazol-1 -yl)-ethanone 0-(phenylmethyl)oxime,
1 -(2-methyl-1 -naphthalenyl)-1 H-pyrrole-2,5-dione,
l-(3,5-dichlorophenyl)-3-(2-propenyl)-2,5-pyrrolidindione,
1 -[(diiodomethyl)-sulphonyl]-4-methylbenzene,
1 -[ [2-(2,4-dichlorophenyl)-1,3 -dioxolan-2-yl] -methyl] -1 H-imidazole,
l-[[2-(4-chlorophenyl)-3-phenyloxiranyl]-methyl]-lH-l,2,4-triazole,
1 - [ 1 - [2- [(2,4-dichlorophenyl)-methoxy] -phenyl]-ethenyl] -1 H-imidazole,
l-methyl-5-nonyl-2-(phenylmethyl)-3-pyrrolidinole,
2;6'-dibromo-2-methyl-4l-trifluoromethoxy-4,-trifluoro-iriethyl-l,3-thiazole-5-carboxanilide,
2,2-dichloro-N-[l-(4-chlorophenyl)ethyl]-l-ethyl-3-methyl-cyclopropanecarboxamide,

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2,6-dichloro-5-(methyltMo)-4-pyrimidinyl-thiocyanate,
2,6-dichloro-N-(4-trifluoromethylbenzyl)benzamide,
2,6-dichloro-N- [ [4-(trifluoromethyl)phenyl]methyl]benzamide,
2-(2,3,3-triiodo-2-propenyl)-2H-tetrazole,
2-[(l-methylethyl)sulphonyl]-5-(trichloromethyl)-l,354-thiadiazole,
2-[[6-deoxy-4-0-(4-0-methyl-P-D-glycopyranosyl)-a-D-glucopyranosyl]-amino] methoxy-1 H-pyrrolo [2,3 -d]pyrimidine-5-carbonitrile,
2-aminobutane,
2-bromo-2-(bromomethyl)pentanedinitrile,
2-cUoro-N-(2,3-dihydro-lJ,3-trimethyl-lH-inden-4-yl)-3-pyridinecarboxamide,
2-chloro-N-(2,6-dimethylphenyl)-N-(isothiocyanatomethyl)acetamide,
2-phenylphenol (OPP),
3,4-dicbloro-l-[4-(difluoromethoxy)phenyl]-lH-pyrrole-2,5-dione,
3,5 -dichloro-N-[cy ano [(1 -methyl-2-propynyl)oxy]methyl]benzamide,
3 -(1,1 -dimethylpropyl-1 -oxo)-1 H-indene-2-carbonitrile,
3-[2-(4-chlorophenyl)-5-ethoxy-3-isoxazolidinyl]pyridine,

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4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1 H-imidazole-1 -sulphonamide,
4-methyl-tetrazolo [ 1,5 -a] quinazolin-5 (4H)-one,
8-(l, 1 -dimethylethyl)-N-ethyl-N-propyl-l ,4-dioxaspiro[4.5]decane-2-methanamine,
8-hydroxyquinoline sulphate,
9H-xanthene-2-[(phenylamino)carbonyl]-9-carboxylic hydrazide,
bis( 1 -methylethyl)-3 -methyl-4-[(3 -methylbenzoyl)oxy] -2,5-thiophenedicarboxylate,
cis-1 -(4-chlorophenyl)-2-( 1H-1,2,4-triazol-1 -yl)cycloheptanol,
cis-4-[3-[4-(l, 1 -dimethylpropyl)phenyl-2-methylpropyl]-2,6-dimethylmorpholine hydrochloride,
ethyl [(4-chlorophenyl)azo]cyanoacetatej,
potassium bicarbonate,
methanetetrathiol-sodium salt,
methyl l-(2,3-dmydro-2,2-dimethyl-lH-inden-l-yl)-lH-imidazole-5-carboxylate,
methyl N-(2,6-dimethylphenyl)-N-(5-isoxazolylcarbonyl)-DL-alaninate,
methyl N-(chloroacetyl)-N-(2,6-dimethylphenyl)-DL-alaninate,
N-(2,3-dichloro-4-hydroxyphenyl)-l-methyl-cyclohexanecarboxamide,

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N-(2,6-dimethylphenyl)-2-methoxy-N-(tetrahydro-2-oxo-3-fiiranyl)acetaimde,
N-(2,6-dimethylphenyl)-2-methoxy-N-(tetrahydro-2-oxo-3-thienyl)acetamide,
N-(2-cMoro-4-rntrophenyl)-4-methyl-3-nitro-berizenesulprionamide,
N-(4-cyclohexylphenyl)-1,4,5,64e1xahydro-2-pyrimidinamine,
N-(4-hexylphenyl)-1,4,5,6-tetrahydro-2-pyrimidinarriine,
N-(5-chloro-2-methylphenyl)-2-methoxy-N-(2-oxo-3-oxazolidinyl)acetamide,
N-(6-methoxy)-3-pyridinyl)cyclopropanecarboxamide,
N-[2,2,24richloro-l-[(chloroacetyl)amino]ethyl]benzamide,
N-[3-cMoro-4,5-bis(2-propinyloxy)phenyl]-N'-methoxymethanrmidamide,
N-formyl-N-hydroxy-DL-alanine-sodium salt,
0,0-diethyl [2-(dipropylamino)-2-oxoethyl]ethylphosphoramidothioate,
O-methyl S-phenyl phenylpropylphosphoramidothioate,
S-methyl 1,2,3-benzotbiadiazole-7-carbothioate, spiro[2H]-1 -benzopyrane-2,1 X3HHsobenzofuran]-3'-one,
Bactericides:

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bronopol, dichlorophen, nitrapyrin, nickel dimethyldithiocarbamate, kasugamycin, octhilinone, furancarboxylic acid, oxytetracyclin, probenazole, streptomycin, tecloftalam, copper sulphate and other copper preparations.
Insecticides / acaricides / nematicides:
abamectin, acephate, acetamiprid, acrinathrin, alanycarb, aldicarb, aldoxycarb, alpha-cypermethrin, alphamethrin, amitraz, avermectin, AZ 60541, azadirachtin, azamethiphos, azinphos A, azinphos M, azocyclotin,

Bacillus popilliae, Bacillus sphaericus, Bacillus subtilis, Bacillus thuringiensis,
baculoviruses, Beauveria bassiana, Beauveria tenella, bendiocarb, benfuracarb,
bensultap, benzoximate, betacyfluthrin, bifenazate, bifenthrin, bioethanomethrin,
biopermethrin, BPMC, bromophosA, bufencarb, buprofezin, butathiofos,
butocarboxim, butylpyridaben,
cadusafos, carbaryl, carbofuran, carbophenothion, carbosulfan, cartap, chloethocarb,
chlorethoxyfos, chlorfenapyr, chlorfenvinphos, chlorfluazuron, chlormephos,
chlorpyrifos, chlorpyrifos M, chlovaporthrin, cis-resmethrin, cispermethrin,
clocythrin, cloethocarb, clofentezine, cyanophos, cycloprene, cycloprothrin,
cyfluthrin, cyhalothrin, cyhexatin, cypermethrin, cyromazine,
deltamethrin, demeton M, demeton S, demeton-S-methyl, diafenthiuron, diazinon,
dichlorvos, diflubenzuron, dimethoate, dimethylvinphos, diofenolan, disulfoton,
docusat-sodium, dofenapyn,
eflusilanate, emamectin, empenthrin, endosulfan, Entomopfthora spp., esfenvalerate, ethiofencarb, ethion, ethoprophos, etofenprox, etoxazole, etrimfos,
fenamiphos, fenazaquin, fenbutatin oxide, fenitrothion, fenothiocarb, fenoxacrim,
fenoxycarb, fenpropathrin, fenpyrad, fenpyrithrin, fenpyroximate, fenvalerate,

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fipronil, fluazinam, fluazuron, flubrocythrinate, flucycloxuron, flucythrinate, fiufenoxuron, flutenzine, fluvalinate, fonophos, fosmethilan, fosthiazate, fubfenprox, furathiocarb,
granulosis viruses,
halofenozide, HCH, heptenophos, hexaflumuron, hexythiazox, hydroprene,
imidacloprid, indoxacarb, isazofos, isofenphos, isoxathion, ivermectin,
nuclear polyhedrosis viruses,
lambda-cyhalothrin, lufenuron,
malathion, mecarbam, metaldehyde, methamidophos, Metharhizium anisopliae,
Metharhizium flavoviride, methidathion, methiocarb, methomyl,. methoxyfenozide, metolcarb, metoxadiazone, mevinphos, milbemectin, monocrotophos,
naled, nitenpyram, nithiazine, novaluron,
omethoate, oxamyl, oxydemethon M,
Paecilomyces fumosoroseus, parathion A, parathion M, permethrin, phenthoate,
phorate, phosalone, phosmet, phosphamidon, phoxim, pirimicarb, pirimiphos A,
pirimiphos M, profenofos, promecarb, propargite, propoxur, prothiofos, prothoate,
pymetrozine, pyraclofos, pyresmethrin, pyrethrum, pyndaben, pyndathion, pyrimidifen, pyriproxyfen,
quinalphos,
ribavirin,

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salithion, sebufos, silafluofen, spinosad, spirodiclofen, spiromesifen, sulfotep, sulprofos,
tau-fluvalinate, tebufenozide, tebufenpyrad, tebupirimiphos, teflubenzuron,
tefluthrin, temephos, temivinphos, terbufos, tetrachlorvinphos, theta-cypermethrin,
thiaclopnd thiamethoxam, thiamethoxam, thiapronil, thiatriphos, thiocyclam
hydrogen oxalate, thiodicarb, thiofanox, thuringiensin, tralocythrin, tralomethrin,
triarathene, tnazamate, triazophos, triazuron, trichlophenidine, tnchlorfon,
triflumuron, trimethacarb,



vamidothion, vaniliprole, Verticillium lecanii,
YI5302,
zeta-cypermethrin, zolaprofos,





(lR-cis)-[5-(phenylmethyl)-3-furanyl]methyl 3-[(dihydro-2-oxo-3(2H)furanylidene)-methyl]-2,2-dimethylcyclopropanecarboxylate,
(3-phenoxyphenyl)methyl2,2,3,3-tetramethylcyclopropanecarboxylate,
l-[(2-chloro-54hiazolyl)methyl]tetrahydro-3,5-dimethyl-N-nitro-l,3,5-triazine-2(lH)-imine,





2-(2-chloro-6-fluorophenyl)-4- [4-( 1,1 -dimethylethyl)phenyl] -4,5 -dihydrooxazole,
2-(acetyloxy)-3 -dodecyl-1,4-naphthalenedione,

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2-chloro-N-[[[4-(2,2-dichloro-1,1 -difluoroethoxy)phenyl]amino]carbonyl]-benzamide,
3-methylphenyl propylcarbamate,
4-[4-(4-ethoxyphenyl)-4-methylpentyl]-l-fluoro-2-phenoxybenzene,
4-chloro-2-(l,l-dimethylethyl)-5-[[2-(2,6-dimethyl-4-phenoxyphenoxy)ethyl]thio]-3 (2H)-pyridazinone,
4-chloro-2-(2-chloro-2-methylpropyl)-5-[(6-iodo-3-pyridinyl)methoxy]-3(2H)-pyridazinone,
4-chloro-5-[(6-chloro-3-pyridinyl)methoxy]-2-(3,4-dichlorophenyl)-3(2H)-pyridazinone,
Bacillus thuringiensis strain EG-2348,
[2-benzoyl-1-(1,1 -dimethylethyl)hydrazinobenzoic acid,
2,2-dimethyl-3 -(2,4-dichlorophenyl)-2-oxo-1 -oxaspiro[4.5]dec-3 -en-4-yl butanoate,
[3-[(6-chloro-3-pyridinyl)methyl]-2-thiazolidinylidene]cyanamide,
dihydro-2-(nitromethylene)-2H-l,3-thiazine-3(4H)carboxaldehyde,
ethyl [2-[[l,6-dihydro-6-oxo-l-(phenylmethyl)-4-pyridazinyl]oxy]ethyl]carbamate,
N-(3,4,4-trifluoro-l-oxo-3-butenyl)glycine,
N-(4-chlorophenyl)-3 - [4-(difluoromethoxy)phenyl] -4,5 -dihydro-4-phenyl-1H-pyrazole-1-carboxamide,

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N-methyl-N'-(l -methyl-2-propenyl)-1,2-hydrazinedicarbothioamide,
N-methyl-N'-2-propenyl-1,2-hydrazinedicarbothioamide,
0,0-diethyl [2-(dipropylamino)-2-oxoethyl]-ethylphosphoramidothioate.
It is also possible to admix other known active compounds, such as herbicides or fertilizers and growth regulators.

When used as insecticides, the active compound combinations according to the
invention can furthermore be present in their commercially available formulations
and in the use forms, prepared from these formulations, as a mixture with synergistic
agents. Synergistic agents are compounds which increase the action of the active
compounds, without it being necessary for the synergistic agent added to be active
itself.
The active compound content of the use forms prepared from the commercially
available formulations can vary within wide limits. The active compound
concentration of the use forms can be from 0.0000001 to 95% by weight of active
compound, preferably between 0.0001 and 1% by weight.
The compounds are employed in a customary manner appropriate for the use forms.
When used against hygiene pests and pests of stored products, the active compound
combinations are distinguished by an excellent residual action on wood and clay as well as a good stability to alkali on limed substrates.
The active compound combinations according to the invention act not only against
plant, hygiene and stored product pests, but also in the veterinary medicine sector
against animal parasites (ectoparasites), such as hard ticks, soft ticks, mange mites,

Le A 35 814-Foreign Countries
leaf mites, flies (biting and licking), parasitic fly larvae, lice, hair lice, feather lice and fleas. These parasites include:
From the order of the Anoplurida, for example, Haematopinus spp., Linognathus spp., Pediculus spp., Phtirus spp. and Solenopotes spp.
From the order of the Mallophagida and the suborders Amblycerina and Ischnocerina, for example, Trimenopon spp., Menopon spp., Trinoton spp., Bovicola spp., Werneckiella spp., Lepikentron spp., Damalina spp., Trichodectes spp. and Felicolaspp.
From the order of the Diptera and the suborders Nematocerina and Brachycerina, for example, Aedes spp., Anopheles spp., Culex spp., Simulium spp., Eusimulium spp., Phlebotomus spp., Lutzomyia spp., Culicoides spp., Chrysops spp., Hybomitra spp., Atylotus spp., Tabanus spp., Haematopota spp., Philipomyia spp., Braula spp., Musca spp., Hydrotaea spp., Stomoxys spp., Haematobia spp., Morellia spp., Fannia spp., Glossina spp., Calliphora spp., Lucilia spp., Chrysomyia spp., Wohlfahrtia spp., Sarcophaga spp., Oestrus spp., Hypoderma spp., Gasterophilus spp., Hippobosca spp., Lipoptena spp. and Melophagus spp.
From the order of the Siphonapterida, for example Pulex spp., Ctenocephalides spp., Xenopsylla spp. and Ceratophyllus spp.
From the order of the Heteropterida, for example, Cimex spp., Triatoma spp., Rhodnius spp. and Panstrongylus spp.
From the order of the Blattarida, for example Blatta orientalis, Periplaneta americana, Blattela germanica and Supella spp.
From the subclass of the Acaria (Acarida) and the orders of the Meta- and Mesostigmata, for example, Argas spp., Ornithodorus spp., Otobius spp., Ixodes spp.,

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Amblyomma spp., Boophilus spp., Dermacentor spp., Haemophysalis spp., Hyalomma spp., Rhipicephalus spp., Dermanyssus spp., Raillietia spp., Pneumonyssus spp., Sternostoma spp. and Varroa spp.
From the order of the Actinedida (Prostigmata) und Acaridida (Astigmata), for
example, Acarapis spp., Cheyletiella spp., Ornithocheyletia spp., Myobia spp.,
Psorergates spp., Demodex spp., Trombicula spp., Listrophorus spp., Acarus spp.,
Tyrophagus spp., Caloglyphus spp., Hypodectes spp., Pterolichus spp., Psoroptes
spp., Chorioptes spp., Otodectes spp., Sarcoptes spp., Notoedres spp.,
Knemidocoptes spp., Cytodites spp. and Laminosioptes spp.
The active compound combinations according to the invention are also suitable for
controlling arthropods which infest agricultural productive livestock, such as, for
example, cattle, sheep, goats, horses, pigs, donkeys, camels, buffalo, rabbits,
chickens, turkeys, ducks, geese and bees, other pets, such as, for example, dogs, cats,
caged birds and aquarium fish, and also so-called test animals, such as, for example,
hamsters, guinea pigs, rats and mice. By controlling these arthropods, cases of death
and reduction in productivity (for meat, milk, wool, hides, eggs, honey, etc.) should
be diminished, so that more economic and easier animal husbandry is possible by use
of the active compounds according to the invention.
The active compound combinations according to the invention are used in the veterinary sector in a known manner by enteral administration in the form of, for example, tablets, capsules, potions, drenches, granules, pastes, boluses, the feed-
through process and suppositories, by parenteral administration, such as, for
example, by injection (intramuscular, subcutaneous, intravenous, intraperitoneal and the like), implants by nasal administration, by dermal use in the form, for example, of dipping or bathing, spraying, pouring on and spotting on, washing and powdering, and also with the aid of moulded articles containing the active compound, such as
collars, ear marks, tail marks, limb bands, halters, marking devices and the like.

Le A 35 814-Foreign Countries
When used for cattle, poultry, pets and the like, the active compounds can be used as formulations (for example powders, emulsions, free-flowing compositions), which comprise the active compounds in an amount of 1 to 80% by weight, directly or after 100 to 10 000-fold dilution, or they can be used as a chemical bath.
It has furthermore been found that the active compound combinations according to the invention also have a strong insecticidal action against insects which destroy industrial materials.
The following insects may be mentioned as examples and as preferred - but without
limitation:
Beetles, such as
Hylotrupes bajulus, Chlorophorus pilosis, Anobium punctatum, Xestobium
rufovillosum, Ptilinus pecticornis, Dendrobium pertinex, Ernobius mollis, Priobium
carpini, Lyctus brunneus, Lyctus africanus, Lyctus planicollis, Lyctus linearis,
Lyctus pubescens, Trogoxylon aequale, Minthes rugicollis, Xyleborus spec.
Tryptodendron spec. Apate monachus, Bostrychus capucins, Heterobostrychus
brunneus, Sinoxylon spec. Dinoderus minutus.
Hymenopterons, such as
Sirex juvencus, Urocerus gigas, Urocerus gigas taignus, Urocerus augur.
Termites, such as
Kalotermes flavicollis, Cryptotermes brevis, Heterotermes indicola, Reticulitermes flavipes, Reticulitermes santonensis, Reticulitermes lucifugus, Mastotermes darwiniensis, Zootermopsis nevadensis, Coptotermes formosanus.
Bristletails, such as Lepisma saccarina.

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Industrial materials in the present connection are to be understood as meaning non¬living materials, such as, preferably, plastics, adhesives, sizes, papers and cards, leather, wood and processed wood products and coating compositions.
Wood and processed wood products are materials to be protected, especially preferably, from insect infestation.
Wood and processed wood products which can be protected by the agent according
to the invention or mixtures comprising this are to be understood as meaning, for
example:
building timber, wooden beams, railway sleepers, bridge components, boat jetties,
wooden vehicles, boxes, pallets, containers, telegraph poles, wood panelling, wooden
windows and doors, plywood, chipboard, joinery or wooden products which are used
quite generally in house-building or in building j oinery.
The active compound combinations can be used as such, in the form of concentrates or in generally customary formulations, such as powders, granules, solutions, suspensions, emulsions or pastes.

The formulations mentioned can be prepared in a manner known per se, for example by mixing the active compounds with at least one solvent or diluent, emulsifier, dispersing agent and/or binder or fixing agent, a water repellent, if appropriate siccatives and UV stabilizers and if appropriate dyestuffs and pigments, and also
other processing auxiliaries.
The insecticidal compositions or concentrates used for the preservation of wood and wood-derived timber products comprise the active compound according to the invention in a concentration of 0.0001 to 95% by weight, in particular 0.001 to 60% by weight.

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The amount of the compositions or concentrates employed depends on the nature and
occurrence of the insects and on the medium. The optimum amount employed can be
determined for the use in each case by a series of tests. In general, however, it is
sufficient to employ 0.0001 to 20% by weight, preferably 0.001 to 10% by weight, of
the active compound, based on the material to be preserved.
Solvents and/or diluents which are used are an organic-chemical solvent or solvent
mixture and/or an oily or oil-like organic-chemical solvent or solvent mixture of low
volatility and/or a polar organic-chemical solvent or solvent mixture and/or water,
and if appropriate an emulsifier and/or wetting agent.
Organic-chemical solvents which are preferably used are oily or oil-like solvents
having an evaporation number above 35 and a flashpoint above 30°C, preferably
above 45°C. Substances which are used as such oily or oil-like water-insoluble
solvents of low volatility are appropriate mineral oils or aromatic fractions thereof, or
solvent mixtures containing mineral oils, preferably white spirit, petroleum and/or alkylbenzene.
Mineral oils having a boiling range from 170 to 220°C, white spirit having a boiling
range from 170 to 220°C, spindle oil having a boiling range from 250 to 350°C,
petroleum and aromatics having a boiling range from 160 to 280°C, terpentine oil and the like, are advantageously employed.
In a preferred embodiment, liquid aliphatic hydrocarbons having a boiling range
from 180 to 210°C or high-boiling mixtures of aromatic and aliphatic hydrocarbons
having a boiling range from 180 to 220°C and/or spindle oil and/or monochloronaphthalene, preferably a-monochloronaphthalene, are used.
The organic oily or oil-like solvents of low volatility which have an evaporation
number above 35 and a flashpoint above 30°C, preferably above 45°C, can be
replaced in part by organic-chemical solvents of high or medium volatility, providing

Le A 35 814-Foreign Countries

that the solvent mixture likewise has an evaporation number above 35 and a flashpoint above 30°C, preferably above 45°C, and that the insecticide/fungicide mixture is soluble or emulsifiable in this solvent mixture.
According to a preferred embodiment, some of the organic-chemical solvent or solvent mixture is replaced by an aliphatic polar organic-chemical solvent or solvent mixture. Aliphatic organic-chemical solvents containing hydroxyl and/or ester and/or ether groups, such as, for example, glycol ethers, esters or the like, are preferably used.

Organic-chemical binders which are used in the context of the present invention are the synthetic resins and/or binding drying oils which are known per se, are water-dilutable and/or are soluble or dispersible or emulsifiable in the orgamc-chemical solvents employed, in particular binders consisting of or comprising an acrylate
resin, a vinyl resin, for example polyvinyl acetate, polyester resin, polycondensation
or polyaddition resin, polyurethane resin, alkyd resin or modified alkyd resin, phenolic resin, hydrocarbon resin, such as indene-curnarone resin, silicone resin, drying vegetable oils and/or drying oils and/or physically drying binders based on a natural and/or synthetic resin.

The synthetic resin used as the binder can be employed in the form of an emulsion, dispersion or solution. Bitumen or bituminous substances can also be used as binders in an amount of up to 10% by weight. Dyestuffs, pigments, water-repelling agents, odour correctants and inhibitors or anticorrosive agents and the like which are known
per se can additionally be employed.
It is preferred according to the invention for the composition or concentrate to
comprise, as the organic-chemical binder, at least one alkyd resin or modified alkyd
resin and/or one drying vegetable oil. Alkyd resins having an oil content of more
than 45% by weight, preferably 50 to 68% by weight, are preferably used according
to the invention.

Le A 35 814-Foreign Countries

All or some of the binder mentioned can be replaced by a fixing agent (mixture) or a plasticizer (mixture). These additives are intended to prevent evaporation of the active compounds and crystallization or precipitation. They preferably replace 0.01 to 30% of the binder (based on 100% of the binder employed).
The plasticizers originate from the chemical classes of phthalic acid esters, such as
dibutyl, dioctyl or benzyl butyl phthalate, phosphoric acid esters, such as tributyl
phosphate, adipic acid esters, such as di-(2-ethylhexyl) adipate, stearates, such as
butyl stearate or amyl stearate, oleates, such as butyl oleate, glycerol ethers or higher
molecular weight glycol ethers, glycerol esters and p-toluenesulphonic acid esters.
Fixing agents are based chemically on polyvinyl alkyl ethers, such as, for example, polyvinyl methyl ether or ketones, such as benzophenone or ethylenebenzophenone.
Possible solvents or diluents are, in particular, also water, if appropriate as a mixture with one or more of the abovementioned organic-chemical solvents or diluents, emulsifiers and dispersing agents.
Particularly effective preservation of wood is achieved by impregnation processes on
a large industrial scale, for example vacuum, double vacuum or pressure processes.
The ready-to-use compositions can also comprise other insecticides, if appropriate, and also one or more fungicides, if appropriate.
The active compound combinations according to the invention can also be used for protecting against colonization of articles, especially ships hulls, screens, nets, constructions, quays and signalling equipment, which come into contact with seawater or brackish water.

Le A 35 814-Foreign Countries





Colonization by sessile Oligochaetae, such as Serpulidae, and by shellfish and species of the group Ledamorpha (goose barnacles), such as various Lepas and Scalpellum species, or by species of the group Balanomorpha (acorn barnacles), such as Balanus or Pollicipes species, increases the frictional resistance of ships and leads as a result, through increased energy consumption and frequent spells in dry dock, to a marked increase in the operating costs.
In addition to colonization by algae, for example Ectocarpus sp. and Ceramium sp.,
particular importance is attached to infestation by sessile Entomostraca groups,
which are comprised under the name Cirripedia (cirriped Crustacea).
Surprisingly, it has now been found that the active compound combinations according to the invention have a good antifouling (anti-colonization) effect.
By using active compound combinations according to the invention it is possible to
dispense with the use of heavy metals, such as, for example, in bis(trialkyltin) sulphides, tri-n-butyltin laurate, tri-«-butyltin chloride, copper(I) oxide, triethyltin chloride, tri-n-butyl(2-phenyl-4-chlorophenoxy)tin, tributyltin oxide, molybdenum disulphide, antimony oxide, polymeric butyl titanate, phenyl(bispyridine)bismuth
chloride, tri-n-butyltin fluoride, manganese ethylenebisthiocarbamate, zinc dimethyl-
dithiocarbamate, zinc ethylenebisthiocarbamate, the zinc and copper salts of 2-pyridinethiol 1-oxide, bisdimethyldithiocarbamoylzinc ethylenebisthiocarbamate, zinc oxide, copper(I) ethylenebisdithiocarbamate, copper thiocyanate, copper naphthenate and tributyltin halides, or substantially to reduce the concentration of
these compounds.
If appropriate, the ready-to-use antifouling paints may comprise yet further active compounds, preferably algicides, fungicides, herbicides, molluscicides or other active antifouling active compounds.

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Preferred co-components for the antifouling compositions according to the invention are:
algicides such as
2-tert-butylamino-4-cyclopropylamino-6-methylthio-l,3,5-triazine, dichlorophen, diuron, endothal, fentin acetate, isoproturon, methabenzthiazuron, oxyfluorfen, quinoclamine and terbutryn;
fungicides such as
cyclohexylbenzo[b]thiophenecarboxamide S,S-dioxide, dichlofluanid, fluorfolpet, 3-
iodo-2-propinyl butylcarbamate, tolylfluanid and azoles such as azaconazole, cyproconazole, epoxyconazole, hexaconazole, metconazole, propiconazole and tebuconazole;
molluscicides such as
Fe-chelating agents fentin acetate, metaldehyde, methiocarb, niclosamid, thiodicarb
and trimethacarb;
or customary active antifouling compounds such as
4,5-dichloro-2-octyl-4-isothiazolin-3-one, diiodomethyl paratryl sulfone, 2-(N,N-
dimethylthiocarbamoylthio)-5-nitrothiazyl, potassium, copper, sodium and zinc salts
of 2-pyridinethiole 1-oxide, pyridine triphenylborane, tetrabutyldistannoxane,
2,3,5,6-tetrachloro-4-(methylsulphonyl)-pyridine, 2,4,5,6-
tetrachloroisophthalonitrile, tetramethylthiuram disulphide and 2,4,6-
trichlorophenylmaleimide.
The antifouling compositions used comprise the active compound in a concentration of from 0,001 to 50% by weight, in particular from 0.01 to 20% by weight.
The antifouling compositions furthermore comprise the customary components as
described, for example, in Ungerer, Chem. Ind. 1985, 37, 730-732 and Williams,
Antifouling Marine Coatings, Noyes, Park Ridge, 1973.

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In addition to the algicidal, fungicidal, molluscicidal and insecticidal active compounds, antifouling coating compositions comprise, in particular, binders.
Examples of acknowledged binders are polyvinyl chloride in a solvent system,
chlorinated rubber in a solvent system, acrylic resins in a solvent system especially in
an aqueous system, vinyl chloride/vinyl acetate copolymer systems in the form of
aqueous dispersions or in the form of organic solvent systems,
butadiene/styrene/acrylonitrile rubbers, drying oils, such as linseed oil, resin esters or
modified hard resins in combination with tar or bitumen, asphalt and also epoxy
compounds, small amounts of chlorinated rubber, chlorinated polypropylene and vinyl resins.
The coating compositions also optionally include inorganic pigments, organic
pigments or dyestuffs, which are preferably insoluble in salt water. The coating
compositions may also comprise materials such as rosin, for a controlled release of
the active compounds. The coats may also include plasticizers, modifying agents
which influence the rheological properties, and other conventional constituents. The
active compound combinations according to the invention can also be incorporated
into self-polishing antifouling systems.
The active compounds are also suitable for controlling animal pests, in particular
insects, arachnids and mites, which are encountered in closed rooms, such as, for
example, flats, factory halls, offices, vehicle cabins and the like. They can be used on
their own or in combination with other active compounds and auxiliaries in
household insecticidal products for controlling these pests. They are active against sensitive and resistant species and against all development stages. These pests include:
From the order of the Scorpionidea, for example, Buthus occitanus.

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From the order of the Acarina, for example, Argas persicus, Argas reflexus, Bryobia ssp., Dermanyssus gallinae, Glyciphagus domesticus, Ornithodorus moubat, Rhipicephalus sanguineus, Trombicula alfreddugesi, Neutrombicula autumnalis, Dermatophagoides pteronissimus, Dermatophagoides forinae.
From the order of the Araneae, for example, Aviculariidae, Araneidae.
From the order of the Opiliones, for example, Pseudoscorpiones chelifer, Pseudoscorpiones cheiridium, Opiliones phalangium.

From the order of the Isopoda, for example, Oniscus asellus, Porcellio scaber.
From the order of the Diplopoda, for example, Blaniulus guttulatus, Polydesmus spp.
From the order of the Chilopoda, for example, Geophilus spp.
From the order of the Zygentoma, for example, Ctenolepisma spp., Lepisma saccharina, Lepismodes inquilinus.
From the order of the Blattaria, for example, Blatta orientalies, Blattella germanica,
Blattella asahinai, Leucophaea maderae, Panchlora spp., Parcoblatta spp., Periplaneta australasiae, Periplaneta americana, Periplaneta brunnea, Periplaneta fuliginosa, Supella longipalpa.
From the order of the Saltatoria, for example, Acheta domesticus.
From the order of the Dermaptera, for example, Forficula auricularia.
From the order of the Isoptera, for example, Kalotermes spp., Reticulitermes spp.
From the order of the Psocoptera, for example, Lepinatus spp., Liposcelis spp.

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From the order of the Coleptera, for example, Anthrenus spp., Attagenus spp., Dermestes spp., Latheticus oryzae, Necrobia spp., Ptinus spp., Rhizopertha dominica, Sitophilus granarius, Sitophilus oryzae, Sitophilus zeamais, Stegobium paniceum.

From the order of the Diptera, for example, Aedes aegypti, Aedes albopictus, Aedes
taeniorhynchus, Anopheles spp., Calliphora erythrocephala, Chrysozona pluvialis,
Culex quinquefasciatus, Culex pipiens, Culex tarsalis, Drosophila spp., Fannia
canicularis, Musca domestica, Phlebotomus spp., Sarcophaga carnaria, Simulium
spp., Stomoxys calcitrans, Tipula paludosa.
From the order of the Lepidoptera, for example, Achroia grisella, Galleria mellonella, Plodia interpunctella, Tinea cloacella, Tinea pellionella, Tineola bisselliella.
From the order of the Siphonaptera, for example, Ctenocephalides canis,
Ctenocephalides felis, Pulex irritans, Tunga penetrans, Xenopsylla cheopis.
From the order of the Hymenoptera, for example, Camponotus herculeanus, Lasius
fuliginosus, Lasius niger, Lasius umbratus, Monomorium pharaonis, Paravespula
spp., Tetramorium caespitum.
From the order of the Anoplura, for example, Pediculus humanus capitis, Pediculus humanus corporis, Phthirus pubis.
From the order of the Heteroptera, for example, Cimex hemipterus, Cimex
lectularius, Rhodinus prolixus, Triatoma infestans. In the field of the household insecticides, they are used on their own or in combination with other suitable active compounds, such as phosphoric acid esters, carbamates, pyrethroids, growth regulators or active compounds from other known
classes of insecticides.

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Application is carried out in the form of aerosols, unpressurized sprays, for example pump and atomizer sprays, nebulizers, foggers, foams, gels, vaporizer products with vaporizer tablets made of cellulose or plastic, liquid vaporizers, gel and membrane vaporizers, propeller-operated vaporizers, energyless or passive vaporizer systems, moth papers, moth sachets and moth gels, as granules or dusts, in baits for scattering or bait stations.
When using the active compound combinations according to the invention, the
application rates can be varied within a relatively wide range, depending on the kind
of application. In the treatment of parts of plants, the application rates of the active
compound combination are generally between 0.1 and 10 000 g/ha, preferably between 10 and 1 000 g/ha.
The good insecticidal and acaricidal activity of the active compound combinations
according to the invention is evident from the examples below. While the individual
active compounds exhibit weaknesses with regard to activity, the combinations have an activity which exceeds a simple addition of activities.
A synergistic effect of insecticides and acaricides is always present when the activity
of the active compound combinations exceeds the total of the activities of the active
compounds when applied individually.

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Formula for the calculation of the synergistic activity of a combination of two active compounds
The expected activity for a given combination of two active compounds can be calculated as follows (cf. Carpenter, C.S., "Mammalian Toxicity of 1-naphthyl-iV-methylcarbamate [Sevin Insecticide]", Agricultural and Food Chemistry, Vol. 9, No. 1, pages 30-39,1961):
If
Pa is the proportion of active compound A in the mixture,
Pb is the proportion of active compound B in the mixture,
LC50 (or 95) a is the concentration at which 50% (or 95%) of the animals treated with active compound A are killed and
LC50 (or 95) b is the concentration at which 50% (or 95%) of the animals treated with active compound B are killed,
1
the expected LC 50 (0r 95) (comb.) =
Pa Pb
+
LC 50(or 95) & LC 50(or 95) b
If the calculated LC 50 (or 95) exceeds the value actually obtained and is higher than the confidence interval, the activity of the combination is superadditive, i.e. a synergistic effect exists.

Le A 35 814-Foreign Countries
Use Examples
Example A
Heliothis armigera test
Solvent: 7 parts by weight of dimethylforrnamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Soya bean shoots (glycine max) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with Heliothis armigera caterpillars while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed. The determined kill rates are inserted into Carpenter's formula (see preceding page).
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries
Table A Plant-damaging insects Heliothis armigera test
Active compounds LC50 after 6 days
P-cy fluthrin 0.15 9ppm
clothianidin 0.997 ppm
P-cy fluthrin + clothianidin (1:6)
according to the invention
calc.**0.569 ppm found* O.lppm
found* = activity found
calc.** = activity calculated using Carpenter's formula

Le A 35 814-Foreign Countries
Example B
Myzus test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea), which are heavily infested by the green peach aphid (Myzus persicae) are treated by being dipped into the preparation of active compound of the desired concentration.
After the desired period of time, the killed in % is determined. 100% means that all aphids have been killed. The determined kill rates are inserted into Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries
Table B
Plant-damaging insects
Myzus test
Active compounds LC50 after 6 days
P-cyfluthrin 2.583 ppm
clothianidin 1.013 ppm
p-cyfluthrin + clothianidin (1:1.2) according to the invention
calc.** 1.399 ppm found*0.224 ppm

found* = calc.** =

activity found
activity calculated using Carpenter's formula

Le A 35 814-Foreign Countries
Example C
Plutella test, sensitive strain
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with caterpillars of the diamondback moths (Plutella xylostella, sensitive strain) while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed. The determined kill rates are inserted in Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries
Table C
plant-damaging insects
Plutella test, sensitive strain
Active compounds LC95 after 6 days
p-cyfluthrin 0.699 ppm
clothianidin 42.493 ppm
P-cyfluthrin + clothianidin (1:6) according to the invention
calc.**4.444 ppm found* 0.19 ppm

found* calc.**

activity found
activity calculated using Carpenters formula

Le A 35 814-Foreign Countries
Example D
Phaedon larvae test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with larvae of the mustard beetle (Phaedon cochleariae) while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all beetle larvae have been killed; 0% means that none of the beetle larvae have been killed. The determined kill rates are inserted in Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries
Table D
Plant-damaging insects
Phaedon larvae test
Active compounds LC50 after 6 days
P-cyfluthrin 0.646 ppm
clothianidin 6.708 ppm
P-cyfluthrin + clothianidin (1:6)
according to the invention
calc.**2.865 ppm found*0.389ppm
found* = activity found
calc.** = activity calculated using Carpenter's formula

Le A 35 814-Foreign Countries
Example E
Spodoptera frugiperda test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active
compound is mixed with the stated amounts of solvent and emulsifier, and the
concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with caterpillars of the armyworm (Spodoptera frugiperda) while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed. The determined kill rates are inserted in Carpenter's formula.
In this test, the following combination of active compounds in accordance with the
present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries
Table E
Plant-damaging insects
Spodoptera frugiperda test
Active compounds LC95 after 3 days
P-cyfluthrin 1.113 ppm
clothianidin 6.099 ppm
P-cyfluthrin + clothianidin (1:6) according to the invention
calc.**3.717 ppm found* 0.5 ppm
found* = activity found
calc.** = activity calculated using Carpenter's formula

Le A 35 814-Foreign Countries



Example F
Heliothis armigera test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Soya bean shoots (glycine max) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with Heliothis armigera caterpillars while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed. The determined kill rates are inserted into Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries





Table F Plant-damaging insects Heliothis armigera test

Active compounds

LC50 after 6 days



avermeetin

0.094 ppm



clothianidin

15.0 ppm





avermeetin + clothianidin (1:25)
according to the invention
found* = activity found
calc.** = activity calculated using Carpenter's formula

calc.**2.137 ppm found*0.094ppm

Le A 35 814-Foreign Countries
Example G
Phaedon larvae test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with larvae of the mustard beetle (Phaedon cochleariae) while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all beetle larvae have been killed; 0% means that none of the beetle larvae have been killed. The determined kill rates are inserted in Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries
Table G
Plant-damaging insects
Phaedon larvae test
Active compounds LC95 after 6 days
avermectin 1.431 ppm
clothianidin 11.234 ppm
avermectin + clothianidin (1:25)
according to the invention
calc.**8.850 ppm found*0.449 ppm
found* = activity found
cal
c.** = activity calculated using Carpenter's formula

Le A 35 814-Foreign Countries
Example H
Myzus test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea), which are heavily infested by the green peach aphid (Myzus persicae) are treated by being dipped into the preparation of active compound of the desired concentration.
After the desired period of time, the killed in % is determined. 100% means that all aphids have been killed; 0% means that none of the aphids have been killed. The determined kill rates are inserted into Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries

Table H
Plant-damaging insects
Myzus test
Active compounds LC95 after 1 day
methiocarb 75.000 ppm
clothianidin 5.988 ppm
methiocarb + clothianidin (5:1)
according to the invention
calc.**25.641 ppm found* 1.25 5ppm
found* = activity found
calc.** = activity calculated using Carpenter's formula

Le A 35 814-Foreign Countries
Example I
Spodoptera frugiperda test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with caterpillars of the armyworm (Spodoptera frugiperda) while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed. The determined kill rates are inserted in Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries



Table I
Plant-damaging insects
Spodoptera frugiperda test
LCso after 6 days
Active compounds

methiocarb 51.649 ppm

clothianidin 2.450 ppm
methiocarb + ciothiamdin (1:1)
according to the invention
calc.**4.673 ppm found*0.993 ppm

found* = activity found
calc.** = activity calculated using Carpenter's formula

Le A 35 814-Foreign Countries

Exampie J
Heliothis armigera test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active
compound is mixed with the stated amounts of solvent and emulsifier, and the
concentrate is diluted with emulsifier-containing water to the desired concentration.
Soya bean shoots (glycine max) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with Heliothis armigera caterpillars while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed. The determined kill rates are inserted into Carpenter's formula.
| In this test, the following combination of active compounds in accordance with the
present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries
Table J Plant-damaging insects Heliothis armigera test
Active compounds LC50 after 6 days
emamectin benzoate 0.007 ppm
clothianidin 3.527 ppm
emamectin benzoate + clothianidin (1:500)
according to the invention
calc.**1.757 ppm found*0.004ppm
found* = activity found
calc.** = activity calculated using Carpenter's formula

Le A 35 814-Foreign Countries
Example K
Phaedon larvae test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with larvae of the mustard beetle (Phaedon cochleariae) while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all beetle larvae have been killed; 0% means that none of the beetle larvae have been killed. The determined kill rates are inserted in Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries
Table K
Plant-damaging insects
Phaedon larvae test

Active compounds

LC95 after 6 days



emamectin benzoate

0.072 ppm



clothianidin

17.504 ppm



emamectin benzoate + clothianidin (1:100)
according to the invention
found* = activity found
calc.** = activity calculated using Carpenter's formula

calc. **5.102 ppm found*0.082 ppm

Le A 35 814-Foreign Countries
Example L
Plutella test, sensitive strain
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with caterpillars of the diamondback moths (Plutella xylostella, sensitive strain) while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed. The determined kill rates are inserted in Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries
Table L
Plant-damaging insects
Plutella test, sensitive strain
Active compounds LC95 after 6 days
emamectin benzoate 0.0009 ppm
clothianidin 9.045 ppm
Emamectin benzoate + clothianidin (1:500)
according to the invention
calc.**0.429 ppm found*0.0027 ppm
found* = activity found
calc.** = activity calculated using Carpenter's formula

L6 A35 814 Foreign Countries
Example M
Plutella test, resistant strain
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with caterpillars of the diamondback moths (Plutella xylostella, resistant strain) while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed. The determined kill rates are inserted in Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries
Table M
Plant-damaging insects
Plutella test, resistant strain
Active compounds LC50 after 6 days
emamectin benzoate 0.0012 ppm
clothianidin 27.271 ppm
emamectin benzoate + clothianidin (1:500)
according to the invention
calc.**0.587 ppm found*0.0008 ppm
found* = activity found
calc.** = activity calculated using Carpenter's formula

Le A 35 814-Foreign Countries
Example N
Spodoptera frugiperda test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active
compound is mixed with the stated amounts of solvent and emulsifier, and the
concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with caterpillars of the armyworm (Spodoptera frugiperda) while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed. The determined kill rates are inserted in Carpenter's formula.
In this test, the following combination of active compounds in accordance with the
present application showed a synergisticaily enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries

Table N
Plant-damaging insects
Spodoptera frugiperda test

Active compounds

LC50 after 6 days



emamectin benzoate

0.003 ppm



clothianidin

0.178 ppm





emamectin benzoate + clothianidin (1:500)
according to the invention
found* = activity found
calc.** = activity calculated using Carpenter's formula

calc. **0.159 ppm found*0.0027 ppm

Le A 35 814-Foreign Countries
Example O
Aphis gossypii test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cotton leaves (Gossypium hirsutum), which are heavily infested by the cotton aphid (Aphis gossypii) are treated by being dipped into the preparation of active compound of the desired concentration.
After the desired period of time, the killed in % is determined. 100% means that all aphids have been killed; 0% means that none of the aphids have been killed. The determined kill rates are inserted into Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Table O
Plant-damaging insects
Aphis gossypii test
Active compounds LC95 after 6 days
lambda-cyhalothrin 10.545ppm
clothianidin 4.954ppm
lambda-cyhalothrin + clothianidin (1:1)
according to the invention
calc.**6.757ppm found* found* = activity found
calc.** = activity calculated using Carpenter's formula

Le A 35 814-Foreign Countries
Example P Myzus test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent and emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea), which are heavily infested by the green peach aphid (Myzus persicae) are treated by being dipped into the preparation of active compound of the desired concentration.
After the desired period of time, the killed in % is determined. 100% means that all aphids have been killed; 0% means that none of the aphids have been killed. The determined kill rates are inserted into Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries





Table P
Plant-damaging insects
Myzus test

Active compounds

LC95 after 1 day



lambda-cyhalothrin

11.234ppm



clothianidin

1.303ppm



lambda-cyhalothrin + clothianidin (1:1)
according to the invention
found* = activity found
calc.** = activity calculated using Carpenter's formula

calc.**2.331ppm found* 0.6ppm

Le A 35 814-Foreign Countries

Example Q
Phaedon larvae test
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with the stated amounts of solvent emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation of active compound of the desired concentration and are populated with larvae of the mustard beetle (Phaedon cochleariae) while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all beetle larvae have been killed; 0% means that none of the beetle larvae have been killed. The determined kill rates are inserted in Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries
Table Q
Plant-damaging insects
Phaedon larvae test
Active compounds LC95 after 6 days
lambda-cyhalothrin 11.234ppm
clothianidin 7.690ppm
lambda-cyhalothrin + clothianidin (1:1)
according to the invention
calc.**9.09ppm found* 0.6ppm
found* = activity found
calc.** = activity calculated using Carpenter's formula

Le A 35 814-Foreign Countries
Example R
Plutella test, sensitive strain
Solvent: 7 parts by weight of dimethylformamide
Emulsifier: 2 parts by weight of alkylaryl polyglycol ether
To produce a suitable preparation of active compound, 1 part by weight of active
compound is mixed with the stated amounts of solvent emulsifier, and the concentrate is diluted with emulsifier-containing water to the desired concentration.
Cabbage leaves (Brassica oleracea) are treated by being dipped into the preparation
of active compound of the desired concentration and are populated with caterpillars
of the diamondback moths (Plutella xylostella, sensitive strain) while the leaves are still moist.
After the desired period of time, the kill in % is determined. 100% means that all caterpillars have been killed; 0% means that none of the caterpillars have been killed. The determmed kill rates are inserted in Carpenter's formula.
In this test, the following combination of active compounds in accordance with the present application showed a synergistically enhanced activity compared to the active compounds applied individually:

Le A 35 814-Foreign Countries
Table R
Plant-damaging insects
Plutella test, sensitive strain
Active compounds LC95 after 6 days
lambda-cyhalothrin 0.09ppm
clothianidin 28.46ppm
lambda-cyhalothrin + clothianidin (1:125)
according to the invention
calc.**8.065ppm found* 0.22ppm
found* = activity found
calc.** = activity calculated using Carpenter's formula

Documents:

39-mum-2003-cancelled pages(09-07-2007).pdf

39-mum-2003-claims(granted)-(09-02-2007).doc

39-mum-2003-claims(granted)-(09-02-2007).pdf

39-mum-2003-correspondence(09-02-2007).pdf

39-mum-2003-correspondence(ipo)-(05-10-2007).pdf

39-mum-2003-form 1(19-09-2006).pdf

39-mum-2003-form 18(30-11-2005).pdf

39-mum-2003-form 2(granted)-(09-02-2007).doc

39-mum-2003-form 2(granted)-(09-02-2007).pdf

39-mum-2003-form 3(13-01-2003).pdf

39-mum-2003-form 3(14-02-2003).pdf

39-mum-2003-form 3(18-09-2006).pdf

39-mum-2003-form 5(13-01-2003).pdf

39-mum-2003-form-pct-isa-210-(13-01-2003).pdf

39-mum-2003-petition under rule 137(19-09-2006).pdf

39-mum-2003-petition under rule 138(19-09-2006).pdf

39-mum-2003-power of authority(19-09-2006).pdf


Patent Number 210512
Indian Patent Application Number 39/MUM/2003
PG Journal Number 42/2008
Publication Date 17-Oct-2008
Grant Date 05-Oct-2007
Date of Filing 13-Jan-2003
Name of Patentee BAYER CROPSCIENCE AG
Applicant Address ALFRED-NOBEL-STR. 50, 40789 MONHEIM,
Inventors:
# Inventor's Name Inventor's Address
1 WOLFRAM ANDERSCH SCHLODDERDICHER WEG 77, 51469 BERGISCH GLADBACH,
2 CHRISTOPH ERDELEN UNTERBUSCHERHOF 15, 42799 LEICHLINGEN
3 PETER JESCHKE KALMUNTENER STRASSE 44A, 51467 BERGISCH GLADBACH,
PCT International Classification Number A01N 51/00
PCT International Application Number N/A
PCT International Filing date
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 10203688.8 2002-01-31 Germany