Title of Invention

ISOQUINOLINONE CASPASE INHIBITORS

Abstract The present invention relates to compounds of formula (1); usuful as inhibitors of caspases.The present invention also provided pharmaceutically acceptable composition comprising said compounds,process for preparing the compounds,and method of using the compounds and composition in the treatment of various diseases,conditions, or disorders
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Documents:


Patent Number 210369
Indian Patent Application Number 00083/KOLNP/2005
PG Journal Number 40/2007
Publication Date 05-Oct-2007
Grant Date 03-Oct-2007
Date of Filing 24-Jan-2005
Name of Patentee VERTEX PHARMACEUTICALS INCORPORATED
Applicant Address 130 WAVERLY STREET,CAMBRIDGE,MA 02139 UNITED STATES OF AMERICA.
Inventors:
# Inventor's Name Inventor's Address
1 KNEGTEL,RONALD., 92 ANDERSEY WAY,ABINGDON,OXFORDSHIRE OX 1454 NORTHWEST,GREAT BRITAIN.
2 MORTIMORE,MICHAEL. WALRUS HOUSE,156 THE HILL,BURFORD,GREAT BRITAIN.
3 STUDLEY,JOHN. 29 WILLOW BROOK.ABINGDON,OXFORDSHIRE OX 14 1TD,GREAT BRITAIN.
4 MILLAN,DAVID 25 INKERMAN CLOSE,ABINGDON,OXFORDSHIRE OX 14 1NH,GREAT BRITAIN.
PCT International Classification Number C07 D 217/24
PCT International Application Number PCT/US2003/020557
PCT International Filing date 2003-06-27
PCT Conventions:
# PCT Application Number Date of Convention Priority Country
1 60/392,592 2002-06-28 U.S.A.
2 60/435,073 2002-12-20 U.S.A.