Title of Invention	A METHOD OF INTRODUCING RESTRICTION ENDONUCLEASE RECOGNITION SITE INTERNAL TO A GENE
Abstract	We Claim 1.An improved circulating hot fluid type of apparatus for treatment of Mennorrhagia comprising of a device for removal of dissolved air from the circulating hot fluid having a chamber with at least three ports two of which are in-line with circulating fluid and third port substantially at right angles to the other two ports.

Full Text

THE PATENT ACT 1970 (39 OF 1970) COMPLETE SPECIFICATION [See Section 10] AN IMPROVED DEVICE USED IN THE TREATMENT OF DYSFUNCTIONAL UTERINE BLEEDING (MENORRHEGIA DUE TO A HORMONAL CAUSE) Vartak Taraprakash Prabhakar 87/1/C, Parvati, Sahakarnagar No.2, Swanand Society, PUNE- 411009 Maharashtra, INDIA An Indian And Vartak Rahul Taraprakash 87/1/C, Parvati, Sahakarnagar No,2, Swanand Society, PUNE-411009 Maharashtra, INDIA An Indian THE FOLLOWING SPECIFICATION PARTICULARLY DESCRIBES AND ASCERTAINS THE NATURE OF THIS INVENTION AND THE MANNER IN WHICH IT IS TO BE PERFORMED 1293/MUM/2003 This Invention relates to an improved device used in the treatment of Dysfunctional Uterine Bleeding Mennorrhagia due to hormonal causes (DUB) In treatment of certain types of DUB the endometrium is subjected to controlled heat for a period of time by using a balloon catheter. This treatment is termed as Thermal Ablation. Many variants of balloon catheters and control systems are available in the market .One type of balloon catheter acts as conduit of hot fluid where fluid is heated outside the catheter and circulated in and out of it. Another type has a heating element in the catheter balloon itself, which heats the fluid inside the balloon itself without circulation of fluid. In both the cases the dissolved air in the fluid, which generally is water or with added salts or sugars, can get entrapped inside the balloon. This air acts as an insulated patch inhibiting the effective transmission of heat from fluid to the balloon surface. This "heat deficient" patch area of the balloon may cause inadequate heating of the endometrial tissue in contact with it. 1293/MUM/2003 In this invention, applicable to circulating fluid type of apparatus, a specially designed air-removing device is incorporated wherein the dissolved air, released due to heating of fluid is diverted out from the circulating fluid before it enters the balloon catheter. The device substantially reduces the introduction of air into the catheter balloon. This results in a uniform temperature profile over the complete balloon surface and thus uniform heating of endometrium. A block diagram Figure 1 shows the general arrangement of the circulating type apparatus. Water is heated in a container 1 which is pumped by pump 2 into catheter inlet 3 and out from outlet 4 . In this invention a specially designed chamber with three or more ports is introduced between the heater and the catheter, preferably between the pumping means and the catheter. The geometry of this chamber ( See Figure 2 ) is designed in such a way that the released air gets a good chance to move upwards irrespective of the speed of circulating fluid. The chamber has a cross section much larger than that of the circulating fluid line, preferably 3 to 4 times of fluid line. Due to this larger cross section the speed of the circulating fluid reduces and the trapped air bubbles tend to rise upwards in the chamber. Air removal is achieved by mounting the inlet /outlet ports 10 and 20 substantially horizontally. 1293/MUM/2003 The fluid containing trapped air enters from port 10 and leaves by port 20 . The port 30 has a substantially vertical branch 50 . When hot fluid moves from port 10 to port 20 , the trapped air bubbles tend to rise up on upwardly tapered surfaces 40 and escape to the vertical branch 50 through port 30. This Invention specifically relates to the above mentioned device. The Novel features that increases the efficiency of this device are as follows: In this invention a specially designed chamber with three ports is introduced near to and inline with the hot fluid source. The geometry of this chamber is designed in such a way that the chamber has a larger cross section than the fluid lines due to which the speed of the circulating fluid reduces. The chamber has upwardly tapering surfaces so that released air that enters the chamber gets a good chance to move upwards irrespective to the speed of fluid. This chamber has an internal cross section of at least 3 to 4 times than that of the fluid line ID The two ports of this three-way chamber are connected to the fluid line. The third port faces upwards to which a tube-like extension is given where the air bubbles are trapped . 1293/MUM/2003 The application of this air-removing device is not limited to treatment of DUB. It can also be used wherever a hot fluid is used with a balloon catheter for thermal treatment of any body cavity. 1293/MUM/2003 We Claim 1. An improved circulating hot fluid type of apparatus for treatment of Mennorrhagia comprising of a device for removal of dissolved air from the circulating hot fluid having a chamber with at least three ports two of which are in-line with circulating fluid and third port substantially at right angles to the other two ports. 2. A device as claimed in claim 1 wherein the chamber has cross section preferably 3 to 4 times that of the fluid line. 3. A device as claimed in claim 1 wherein the chamber has walls tapering towards the third port. 4. A device as claimed in claim 1 wherein the third port has an attached tube like means mounted substantially vertically to trap the air bubbles. Dated this 16th June 2004

Documents:

1323-mum-2003-cancelled pages(4-12-2006).pdf

1323-mum-2003-claims(granted)-(4-12-2006).doc

1323-mum-2003-claims(granted)-(4-12-2006).pdf

1323-mum-2003-correspondence 1(16-12-2004).pdf

1323-mum-2003-correspondence 2(4-12-2006).pdf

1323-mum-2003-correspondence(ipo)-(1-5-2007).pdf

1323-mum-2003-drawing(4-12-2006).pdf

1323-mum-2003-form 1(23-11-2005).pdf

1323-mum-2003-form 1(29-12-2003).pdf

1323-mum-2003-form 13(4-12-2006).pdf

1323-mum-2003-form 2(granted)-(4-12-2006).doc

1323-mum-2003-form 2(granted)-(4-12-2006).pdf

1323-mum-2003-form 3(23-5-2006).pdf

1323-mum-2003-form 3(29-12-2003).pdf

1323-mum-2003-form 5(23-11-2004).pdf

1323-mum-2003-power of authority(29-12-2003).pdf

1323-mum-2003-power of authority(4-12-2006).pdf

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