Title of Invention

METHOD FOR ASSEMBLING AND FILLING A DEVICE FLUID DISPENSING PRODUCT

Abstract

A method of assembling and filling a dispenser device for dispensing a fluid substance made up of an active substance and of a propellant, said device comprising a receptacle and a dispenser member, such as a metering valve, for dispensing said fluid substance, said method being characterized in that it comprises the following steps: assembling said dispenser member onto said receptacle in leaktight manner; inserting a determined quantity of propellant into the receptacle and/or into the dispenser member; storing the dispenser device for a determined storage time; checking and/or testing the dispenser devices so as to discard any devices that have defects; and filling the active substance to be dispensed only into those devices which have satisfied said checking and/or testing.

Full Text

FORM 2 THE PATENTS ACT, 1970 [39 OF 1970] COMPLETE SPECIFICATION [See Section 10; Rule 13] "METHOD FOR ASSEMBLING AND FILLING A DEVICE FLUID DISPENSING PRODUCT' VALOIS S.A., of Boite postale G, Le Prieure, F-27110 Le Neubourg, France, The following specification particularly describes the nature of the invention and the manner in which it is to be performed:- The present invention relates to a method of assembling and filling a fluid dispenser device, and it applies more particularly to dispenser devices containing an active substance mixed with or dissolved in a propellant. A dispenser device for dispensing a fluid substance including a propellant generally comprises a receptacle containing both the substance to be dispensed and the propellant, and a dispenser member such as a metering valve mounted on said receptacle and suitable for selectively dispensing the substance contained therein. Between the metering valve and the receptacle, and inside said valve, sealing gaskets seal the device so as to prevent any leakage of the substance and/or of the propellant. The usual method of assembling and filling such a dispenser device consists in fixing the valve to the receptacle, in particular by crimping, in filling the receptacle with the substance to be dispensed and with the propellant, and then in storing the assembled and filled device for a determined duration in order to identify any devices that have sealing defects such as leaks. That method suffers from certain drawbacks. Firstly, the checking for sealing defects is performed on devices that are full of the substance to be dispensed. If a leak is detected, the device in question is discarded so that the active substance that it contains is also lost. That can be a major drawback when the substance is expensive, which-applies in particular to certain pharmaceuticals. Similarly, storing devices filled with the substance can pose cost problems because a device that has a high value is "tied up". In addition, it is frequent for the manufacturer of the device to be different from the manufacturer of the active substance to be dispensed by the dispenser. In which case, the manufacturer of the metering valve delivers its valves to its customer who must then perform all of the remaining steps of the assembling and filling method. In which case, the manufacturer of the substance must have access to the tools appropriate for assembling the device and to the means for storing the devices and for checking them after the storage period. An object of the present invention is to provide a method of assembling and filling a dispenser device for dispensing a fluid substance including a propellant, which method does not suffer from the above-mentioned drawbacks. Another object of the present invention is to provide such an assembling and filling method that is less costly to perform and that increases the efficiency of the line for filling the devices. Another object of the present invention is to provide such an assembling and filling method in which a large proportion of the method, in particular assembly, leak testing, and quality control, is performed on the site of the manufacturer of the dispenser device. The present invention thus provides a method of assembling and filling a dispenser device for dispensing a fluid substance made up of an active substance and of a propellant, said device comprising a receptacle and a dispenser member, such as a metering valve, for dispensing said fluid substance, said method being characterized in that it comprises the following steps: assembling said dispenser member onto said receptacle in leaktight manner; inserting a determined quantity of propellant into the receptacle and/or into the dispenser member; storing the dispenser device for a determined storage time; checking and/or testing the dispenser devices so as to discard any devices that have defects; and filling the active substance to be dispensed only into those devices which have satisfied said checking and/or testing. The method of the present invention thus makes it possible to check the leaktightness of the assembled devices before they are filled with the active substance, which offers a very considerable economic advantage, particularly when the active substances are costly. Thus, the efficiency of the final filling line for filling the device is considerably increased and the losses of said active substance due to sealing defects in the dispenser device are largely eliminated. In addition, if the manufacturer of the substance is not the manufacturer of the dispenser device, then the substance manufacturer handles the filling only, and does not need to have access to the means required for assembling the device. In order to check the leaktightness before the device is finally filled, the present invention makes provision to store the assembled device preferably for a period in the range 7 days to 2 8 days, with a certain determined quantity of propellant, such as hydrofluoro-alkane (HFA) gas, contained in the device. This solution is inexpensive and very effective. The appropriate quantity of propellant is determined to guarantee that the sealing gaskets are put into a sealing condition, and in particular that said gaskets swell when in contact with said propellant during said storage period. By weighing the dispenser devices before and after storage, it is possible to determine which devices have unacceptable leaks. Only those devices which are properly leaktight are then delivered to the active substance manufacturer, who then merely fills the sealed devices with the substance and with the appropriate propellant. Naturally, although a storage period of 28 days is often advantageous, the storage period may be varied in any desired manner. Similarly, the leaktightness of the devices after storage may be checked in any appropriate manner. In addition, during or after the storage period, the device may also be tested to check other characteristics of the device. Thus, the metering accuracy, i.e. the volume dispensed each time the device is actuated, may also be checked. Furthermore, the spray quality achieved when the device is actuated may also be checked. It is also possible to look for any presence of contamination of the substance, such as bacterial contamination of said substance. In this way, only those devices that do not have any defects, i.e. that have passed the various quality tests and checks, are filled with the active substance. Naturally, checks or tests other than those described above may be performed during or after the storage period. Prior to being stored for checking and/or testing purposes, the device may be prepared in various manners. Thus, the receptacle and/or the metering valve may be filled with the determined quantity of propellant before, after, or at the same time as the metering valve is assembled onto the receptacle. In particular, the receptacle is advantageously purged with the propellant before the device is assembled. The metering valve is advantageously assembled onto the receptacle by crimping, but any other suitable assembly technique may also be considered. We CLAIM: 1. A method of assembling and filling a dispenser device for dispensing a fluid substance made up of an active substance and of a propellant, said device comprising a receptacle and a dispenser member, such as a metering valve, for dispensing said fluid substance, said method being characterized in that it comprises the following steps: assembling said dispenser member onto said receptacle in leaktight manner; inserting a determined quantity of propellant into the receptacle and/or into the dispenser member; storing the dispenser device for a determined storage time; checking and/or testing the dispenser devices so as to discard any devices that have defects; and filling the active substance to be dispensed only into those devices which have satisfied said checking and/or testing. 2. A method as claimed in claim 1, in which the step of inserting a determined quantity of propellant is performed before the step of assembling to dispenser member onto the receptacle. 3. A method as claimed in claim 1 or claim 2, in which the step of inserting a determined quantity of propellant comprises purging the receptacle with the propellant. 4. A method as claimed in any preceding claim, in which the storing step is performed for a storage time approximately in the range 7 days to 28 days. 5. A method as claimed in any preceding claim, in which the checking step comprises weighing the dispenser devices before and after the storage time to detect and discard any dispenser devices having sealing defects. 6. A method as claimed in any preceding claim, in which the testing step comprises testing the metering accuracy and/or the spray quality, and/or the presence of any contamination of the substance. 7. A method as claimed in any preceding claim, in which said assembling step is performed by crimping the dispenser member onto the receptacle. 8. A method as claimed in any preceding claim, in which the determined quantity of propellant inserted into the receptacle and/or into the dispenser member before the storage time, and the duration of the storage time are suitable for putting the sealing gaskets into a sealing condition, in particular by said gaskets swelling when in contact with said propellant. Dated this 3rd day of August 2001. JAYANTA PAL) OF REMFRY & SAGAR ATTORNEY FOR THE APPLICANT[S]

Documents:

in-pct-2001-00936-mum-cancelled pages(5-1-2005).pdf

in-pct-2001-00936-mum-claims(granted)-(5-1-2005).doc

in-pct-2001-00936-mum-claims(granted)-(5-1-2005).pdf

in-pct-2001-00936-mum-correspondence(27-3-2006).pdf

in-pct-2001-00936-mum-correspondence(ipo)-(11-10-2006).pdf

in-pct-2001-00936-mum-form 1(3-8-2001).pdf

in-pct-2001-00936-mum-form 19(29-3-2004).pdf

in-pct-2001-00936-mum-form 2(granted)-(5-1-2005).doc

in-pct-2001-00936-mum-form 2(granted)-(5-1-2005).pdf

in-pct-2001-00936-mum-form 3(29-3-2004).pdf

in-pct-2001-00936-mum-form 3(5-1-2005).pdf

in-pct-2001-00936-mum-form 5(29-3-2004).pdf

in-pct-2001-00936-mum-form-pct-ipea-409-(5-1-2005).pdf

in-pct-2001-00936-mum-form-pct-isa-210(5-1-2005).pdf

in-pct-2001-00936-mum-petition under rule 137(5-1-2005).pdf

in-pct-2001-00936-mum-petition under rule 138(5-1-2005).pdf

in-pct-2001-00936-mum-power of authority(3-8-2001).pdf

in-pct-2001-00936-mum-power of authority(5-1-2005).pdf